NO871477D0 - Fremgangsmaate for fremstilling av human plasminogenaktivator. - Google Patents

Fremgangsmaate for fremstilling av human plasminogenaktivator.

Info

Publication number
NO871477D0
NO871477D0 NO871477A NO871477A NO871477D0 NO 871477 D0 NO871477 D0 NO 871477D0 NO 871477 A NO871477 A NO 871477A NO 871477 A NO871477 A NO 871477A NO 871477 D0 NO871477 D0 NO 871477D0
Authority
NO
Norway
Prior art keywords
procedure
plasminogen activator
human plasminogen
manufacturing human
manufacturing
Prior art date
Application number
NO871477A
Other languages
English (en)
Other versions
NO168055C (no
NO871477L (no
NO168055B (no
Inventor
Daniel Thomas Connolly
Joseph Feder
Nicholaos Konstantinos Harakas
Jon Peter Schaumann
Arthur John Wittwer
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of NO871477D0 publication Critical patent/NO871477D0/no
Publication of NO871477L publication Critical patent/NO871477L/no
Publication of NO168055B publication Critical patent/NO168055B/no
Publication of NO168055C publication Critical patent/NO168055C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
NO871477A 1986-04-09 1987-04-08 Fremgangsmaate for fremstilling av human vevplasminogenaktivator og urokinase-type plasminogenaktivator. NO168055C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/849,933 US5132214A (en) 1986-04-09 1986-04-09 Large scale production of plasminogen activator from normal human colon cells

Publications (4)

Publication Number Publication Date
NO871477D0 true NO871477D0 (no) 1987-04-08
NO871477L NO871477L (no) 1987-10-12
NO168055B NO168055B (no) 1991-09-30
NO168055C NO168055C (no) 1992-01-08

Family

ID=25306874

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871477A NO168055C (no) 1986-04-09 1987-04-08 Fremgangsmaate for fremstilling av human vevplasminogenaktivator og urokinase-type plasminogenaktivator.

Country Status (13)

Country Link
US (1) US5132214A (no)
EP (1) EP0241448A3 (no)
JP (1) JPS6322187A (no)
KR (1) KR900002345B1 (no)
AU (1) AU590918B2 (no)
CA (1) CA1282726C (no)
DK (1) DK178487A (no)
ES (1) ES2002685A4 (no)
FI (1) FI871536A (no)
NO (1) NO168055C (no)
NZ (1) NZ219920A (no)
PT (1) PT84637B (no)
ZA (1) ZA872530B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960702A (en) * 1985-09-06 1990-10-02 Codon Methods for recovery of tissue plasminogen activator
AU2921289A (en) * 1987-12-09 1989-07-19 Invitron Corporation Human cell life extension
US4957863A (en) * 1988-01-26 1990-09-18 Monsanto Company Method of increasing yield of t-PA in cell culture
US5089409A (en) * 1989-09-28 1992-02-18 Monsanto Company Method of increasing specific activity of t-pa
DE3942142A1 (de) * 1989-12-20 1991-06-27 Boehringer Mannheim Gmbh Stabilisierung von glykosyliertem t-pa
MX2009002576A (es) * 2006-09-08 2009-03-20 Wyeth Corp Lavado de arginina en purificacion de proteina utilizando cromatografia de afinidad.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904480A (en) * 1972-10-24 1975-09-09 Lilly Co Eli Enhanced production of plasminogen activator
US4190708A (en) * 1978-05-24 1980-02-26 Monsanto Company Production of urokinase
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
GR79202B (no) * 1982-05-05 1984-10-22 Genentech Inc
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
IE56716B1 (en) * 1983-01-19 1991-11-20 Genentech Inc Method for producing human tpa and expression vectors therefor
JPS59187779A (ja) * 1983-04-08 1984-10-24 Wakamoto Pharmaceut Co Ltd ウロキナ−ゼ精製用吸着体
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
US4661453A (en) * 1984-06-19 1987-04-28 American Biogenetic Sciences, Inc. Production of tissue plasminogen activator factor
US4751084A (en) * 1986-02-26 1988-06-14 Monsanto Company Tissue plasminogen activator from normal human colon cells

Also Published As

Publication number Publication date
AU7130287A (en) 1987-10-15
JPS6322187A (ja) 1988-01-29
NO168055C (no) 1992-01-08
KR900002345B1 (ko) 1990-04-12
PT84637A (en) 1987-05-01
NO871477L (no) 1987-10-12
NZ219920A (en) 1989-08-29
CA1282726C (en) 1991-04-09
EP0241448A3 (en) 1988-01-07
DK178487A (da) 1987-10-10
ZA872530B (en) 1988-01-27
PT84637B (pt) 1989-11-30
KR870010182A (ko) 1987-11-30
AU590918B2 (en) 1989-11-23
ES2002685A4 (es) 1988-10-01
US5132214A (en) 1992-07-21
DK178487D0 (da) 1987-04-08
FI871536A (fi) 1987-10-10
FI871536A0 (fi) 1987-04-08
NO168055B (no) 1991-09-30
EP0241448A2 (en) 1987-10-14

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