NO840350L - Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere, og anvendelsen av de saaledes dannede forbindelser til fremstilling av karboksyalkyldipeptider - Google Patents

Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere, og anvendelsen av de saaledes dannede forbindelser til fremstilling av karboksyalkyldipeptider

Info

Publication number
NO840350L
NO840350L NO840350A NO840350A NO840350L NO 840350 L NO840350 L NO 840350L NO 840350 A NO840350 A NO 840350A NO 840350 A NO840350 A NO 840350A NO 840350 L NO840350 L NO 840350L
Authority
NO
Norway
Prior art keywords
dipptides
bicycleic
racemat
alfa
imino
Prior art date
Application number
NO840350A
Other languages
English (en)
Other versions
NO166641B (no
NO166641C (no
Inventor
Rolf Geiger
Volker Teetz
Dietrich Langner
Hansjoerg Urbach
Reiner Henning
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19833303139 external-priority patent/DE3303139A1/de
Priority claimed from DE19833303112 external-priority patent/DE3303112A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO840350L publication Critical patent/NO840350L/no
Priority to NO903546A priority Critical patent/NO171976C/no
Publication of NO166641B publication Critical patent/NO166641B/no
Publication of NO166641C publication Critical patent/NO166641C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54Spiro-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO840350A 1983-01-31 1984-01-30 Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere. NO166641C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO903546A NO171976C (no) 1983-01-31 1990-08-13 Optisk aktive bicykliske imino-alfa-karboksylsyreestere ogsalter derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833303139 DE3303139A1 (de) 1983-01-31 1983-01-31 Verfahren zur herstellung von carboxyalkyldipeptiden
DE19833303112 DE3303112A1 (de) 1983-01-31 1983-01-31 Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren

Publications (3)

Publication Number Publication Date
NO840350L true NO840350L (no) 1984-08-01
NO166641B NO166641B (no) 1991-05-13
NO166641C NO166641C (no) 1991-08-21

Family

ID=25807929

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840350A NO166641C (no) 1983-01-31 1984-01-30 Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere.

Country Status (17)

Country Link
EP (1) EP0115345B1 (no)
JP (1) JPH0788358B2 (no)
KR (1) KR910001438B1 (no)
AU (1) AU566589B2 (no)
CA (2) CA1283249C (no)
DE (1) DE3468415D1 (no)
DK (1) DK174386B1 (no)
ES (2) ES529272A0 (no)
FI (1) FI88153C (no)
GR (1) GR82650B (no)
HU (1) HU191120B (no)
IE (1) IE56654B1 (no)
IL (1) IL70830A (no)
MA (1) MA20020A1 (no)
NO (1) NO166641C (no)
NZ (1) NZ206980A (no)
PT (1) PT78036B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500713A (en) * 1982-09-23 1985-02-19 Usv Pharmaceutical Corporation Therapeutic dipeptides
DE3345355A1 (de) * 1983-12-15 1985-06-27 Hoechst Ag, 6230 Frankfurt Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester
WO1986000896A1 (en) * 1984-07-30 1986-02-13 Schering Corporation NOVEL PROCESS FOR THE PREPARATION OF CIS, ENDOOCTAHYDROCYCLOPENTA ADb BDPYRROLE-2-CARBOXYLATE
HU192914B (en) * 1985-02-11 1987-07-28 Richter Gedeon Vegyeszet Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
US6407262B1 (en) 2001-11-21 2002-06-18 Brantford Chemicals Inc. Process for the preparation of Ramipril
WO2006059347A2 (en) * 2004-12-01 2006-06-08 Morepen Laboratories Limited Improved process for preparation of ramipril
ES2686298T3 (es) 2010-04-20 2018-10-17 Chiral Quest, Inc. Procedimiento enantioselectivo para alaninas beta sustituidas con cicloalquenilo

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids

Also Published As

Publication number Publication date
NZ206980A (en) 1988-05-30
HU191120B (en) 1987-01-28
MA20020A1 (fr) 1984-10-01
PT78036B (de) 1986-05-30
EP0115345B1 (de) 1988-01-07
ES8500228A1 (es) 1984-10-01
GR82650B (no) 1985-02-07
CA1283249C (en) 1991-04-16
KR910001438B1 (ko) 1991-03-07
IL70830A (en) 1988-02-29
FI840350A0 (fi) 1984-01-27
DK41584A (da) 1984-08-01
AU2393384A (en) 1984-08-02
HUT34159A (en) 1985-02-28
IE840210L (en) 1984-07-31
DK41584D0 (da) 1984-01-30
FI840350A (fi) 1984-08-01
AU566589B2 (en) 1987-10-22
NO166641B (no) 1991-05-13
JPH0517439A (ja) 1993-01-26
PT78036A (de) 1984-02-01
ES529272A0 (es) 1984-10-01
DK174386B1 (da) 2003-01-27
EP0115345A1 (de) 1984-08-08
FI88153B (fi) 1992-12-31
DE3468415D1 (en) 1988-02-11
IE56654B1 (en) 1991-10-23
ES531284A0 (es) 1984-12-01
FI88153C (fi) 1993-04-13
CA1317067C (en) 1993-04-27
JPH0788358B2 (ja) 1995-09-27
NO166641C (no) 1991-08-21
ES8501759A1 (es) 1984-12-01
IL70830A0 (en) 1984-04-30

Similar Documents

Publication Publication Date Title
NO159928C (no) Fremgangsmaate til fremstilling av optisk aktive 1-,4-dihydropyridinkarboksylsyreestere.
NO164418C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive naftyridin- og kinolin-karboksylsyre-forbindelser.
PT76937A (en) Process for the preparation of piperidyl esters and/or n-piperydilamides of substituted benzoic acids or dicarbocyclic or heterocyclic carboxylic acids
NO162862C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre.
NO862408D0 (no) Fremgangsmaate for fremstilling av thiazolidin-4(s)-karboksylsyrederivater.
NO801046L (no) Penem-3-karboksylsyrederivater og fremgangsmaate til fremstilling av samme
NO162619C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater
NO840350L (no) Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere, og anvendelsen av de saaledes dannede forbindelser til fremstilling av karboksyalkyldipeptider
NO172051C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksylsyreesterderivater og deglukoteicoplanin
NO883046D0 (no) Fremgangsmaate til fremstilling av chinolonkarboksylsyrer.
DK576784D0 (da) Fremgangsmaade til fremstilling af optisk aktive 3-aminocarboxylsyreestere
DK472388A (da) Fremgangsmaade til fremstilling af carboxylsyreestere
NO833806L (no) Fremgangsmaate for fremstilling av karboksylsyrer og estere derav.
DK558985A (da) Fremgangsmaade til fremstilling af carboxylsyrer
NO170930C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-okso-3-kinolinkarboksylsyrer
NO169231C (no) Fremgangsmaate ved fremstilling av karboksylsyreamider.
PL246322A1 (en) Method of obtaining optically active alpha-chiral carboxylic acid esters
NO903546L (no) Fremgangsmaate til racematoppdeling av optisk aktive bicykliske imino-alfa-karboksylsyreestere, og anvendelsen av de saaledes dannede forbindelser til fremstilling av karboksyalkyldipeptider.
NO168825C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-pyrrolidinyltio-1-azabicyklo (3.2.0) hept-2-en-2-karboksylsyrederivater
NO160446C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive penemkarboksylsyreestere.
NO151618C (no) Fremgangsmaate for fremstilling av cyklopropan-karboksylsyreester-derivater
NO165396C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridin-5-karboksylsyre-estere.
DK196883D0 (da) Fremgangsmade til fremstilling af cyanhydrincarboxylsyreestere
NO905559D0 (no) Forbedret fremgangsmaate til fermentering av karboksylsyrer
ES515476A0 (es) "procedimiento para la preparacion de esteres de acidos n-clorocarbonil-aminocarboxilicos".

Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN