NO820701L - PROCEDURE FOR THE PREPARATION OF 1- (1,3-BENZODIOKSOL-5-YL) -2-PYRROLIDINON. - Google Patents
PROCEDURE FOR THE PREPARATION OF 1- (1,3-BENZODIOKSOL-5-YL) -2-PYRROLIDINON.Info
- Publication number
- NO820701L NO820701L NO820701A NO820701A NO820701L NO 820701 L NO820701 L NO 820701L NO 820701 A NO820701 A NO 820701A NO 820701 A NO820701 A NO 820701A NO 820701 L NO820701 L NO 820701L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- benzodioksol
- pyrrolidinon
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Forbindelsen med formel (I),. og syreaddisjonssalter derav er verdifulle innen medisinen ved behandlingen eller profylaksen av smerte, betennelse eller feber. Forbindelsen og dens salter kan administreres alene eller i form av et farmasøytisk preparat. Forbindelsen kan fremstilles ved fremgangsmåter som er analoge med kjente fremgangsmåter, eller f.eks. ved å ring-slutte et 4-halo-N-(3,4-metylendioksyfenyl)butyra-mid i nærvær av vandig natriumhydroksyd og en fase-overføringskatalysator slik som trietylbenzyl-ammoniumklorid.The compound of formula (I),. and acid addition salts thereof are valuable in medicine in the treatment or prophylaxis of pain, inflammation or fever. The compound and its salts may be administered alone or in the form of a pharmaceutical composition. The compound can be prepared by methods analogous to known methods, or e.g. by cyclizing a 4-halo-N- (3,4-methylenedioxyphenyl) butyramide in the presence of aqueous sodium hydroxide and a phase transfer catalyst such as triethylbenzylammonium chloride.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8107090 | 1981-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO820701L true NO820701L (en) | 1982-09-07 |
Family
ID=10520195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO820701A NO820701L (en) | 1981-03-06 | 1982-03-05 | PROCEDURE FOR THE PREPARATION OF 1- (1,3-BENZODIOKSOL-5-YL) -2-PYRROLIDINON. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4431662A (en) |
| EP (1) | EP0065082B1 (en) |
| JP (1) | JPS57167983A (en) |
| KR (1) | KR830009080A (en) |
| AR (1) | AR231981A1 (en) |
| AT (1) | AT381703B (en) |
| AU (1) | AU549146B2 (en) |
| CA (1) | CA1178280A (en) |
| DD (1) | DD202024A5 (en) |
| DE (1) | DE3268215D1 (en) |
| DK (1) | DK97682A (en) |
| ES (2) | ES8305759A1 (en) |
| FI (1) | FI70893C (en) |
| GR (1) | GR75887B (en) |
| IL (1) | IL65178A (en) |
| IT (1) | IT1200921B (en) |
| MC (1) | MC1455A1 (en) |
| NO (1) | NO820701L (en) |
| NZ (1) | NZ199929A (en) |
| PL (1) | PL137717B1 (en) |
| PT (1) | PT74538B (en) |
| SU (1) | SU1241992A3 (en) |
| ZA (1) | ZA821490B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123288A (en) * | 1982-07-16 | 1984-02-01 | Wellcome Found | Anti-thrombotic agent |
| JPS5965071A (en) * | 1982-09-02 | 1984-04-13 | ザ・ウエルカム・フアウンデ−シヨン・リミテツド | Analgesic antiinflammatory |
| NZ255097A (en) * | 1992-07-24 | 2001-04-27 | Univ California | Heterocyclic derivatives (such as 1-(1,4-bgenzodioxan-5-ylcarbonyl)-1,2,3,6-tetrahydropyridine) and medicaments that enhance synaptic responses |
| US5852008A (en) * | 1995-01-24 | 1998-12-22 | The Regents Of The University Of California | Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors |
| EP1219306A1 (en) | 2000-12-29 | 2002-07-03 | Nicox S.A. | Compositions comprising cyclodextrins and NO- releasing drugs |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4110105A (en) * | 1975-03-28 | 1978-08-29 | Stauffer Chemical Company | Aromatic N-substituted halo-substituted-2-pyrrolidinones and their utility as herbicides |
| CA1115212A (en) * | 1978-02-10 | 1981-12-29 | Emilio Kyburz | Pyrrolidine derivatives |
| FR2431489A1 (en) * | 1978-07-18 | 1980-02-15 | Unicler | 3- or 4-Methoxy-phenyl-imino-methyl pyridine derivs. - useful as analgesics with good gastric tolerance, and in some cpds. cases as sedatives |
| EP0022737B1 (en) * | 1979-07-16 | 1982-06-09 | Laboratoires Sarget S.A. | Imines derived from 5-amino-1,3-benzodioxole useful as medicines, and their preparation |
| US4263038A (en) * | 1979-10-01 | 1981-04-21 | Stauffer Chemical Company | Synergistic herbicidal compositions |
-
1982
- 1982-02-26 US US06/353,007 patent/US4431662A/en not_active Expired - Fee Related
- 1982-03-05 AR AR288648A patent/AR231981A1/en active
- 1982-03-05 ZA ZA821490A patent/ZA821490B/en unknown
- 1982-03-05 ES ES510181A patent/ES8305759A1/en not_active Expired
- 1982-03-05 EP EP82101746A patent/EP0065082B1/en not_active Expired
- 1982-03-05 FI FI820780A patent/FI70893C/en not_active IP Right Cessation
- 1982-03-05 GR GR67508A patent/GR75887B/el unknown
- 1982-03-05 DK DK97682A patent/DK97682A/en not_active Application Discontinuation
- 1982-03-05 DD DD82237911A patent/DD202024A5/en unknown
- 1982-03-05 SU SU823402605A patent/SU1241992A3/en active
- 1982-03-05 KR KR1019820000954A patent/KR830009080A/en unknown
- 1982-03-05 IL IL65178A patent/IL65178A/en unknown
- 1982-03-05 IT IT47929/82A patent/IT1200921B/en active
- 1982-03-05 NO NO820701A patent/NO820701L/en unknown
- 1982-03-05 PT PT74538A patent/PT74538B/en unknown
- 1982-03-05 AT AT0089182A patent/AT381703B/en not_active IP Right Cessation
- 1982-03-05 AU AU81149/82A patent/AU549146B2/en not_active Ceased
- 1982-03-05 DE DE8282101746T patent/DE3268215D1/en not_active Expired
- 1982-03-05 JP JP57035013A patent/JPS57167983A/en active Pending
- 1982-03-05 CA CA000397756A patent/CA1178280A/en not_active Expired
- 1982-03-05 NZ NZ199929A patent/NZ199929A/en unknown
- 1982-03-05 PL PL1982235332A patent/PL137717B1/en unknown
- 1982-03-05 MC MC821578A patent/MC1455A1/en unknown
-
1983
- 1983-01-10 ES ES518868A patent/ES8501760A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ATA89182A (en) | 1986-04-15 |
| MC1455A1 (en) | 1983-02-01 |
| DE3268215D1 (en) | 1986-02-13 |
| NZ199929A (en) | 1985-01-31 |
| SU1241992A3 (en) | 1986-06-30 |
| AU8114982A (en) | 1982-09-09 |
| US4431662A (en) | 1984-02-14 |
| IL65178A0 (en) | 1982-05-31 |
| FI70893B (en) | 1986-07-18 |
| IT1200921B (en) | 1989-01-27 |
| FI820780L (en) | 1982-09-07 |
| PT74538A (en) | 1982-04-01 |
| AR231981A1 (en) | 1985-04-30 |
| AT381703B (en) | 1986-11-25 |
| GR75887B (en) | 1984-08-02 |
| ES518868A0 (en) | 1984-12-01 |
| EP0065082A3 (en) | 1983-03-16 |
| PL137717B1 (en) | 1986-07-31 |
| ES8501760A1 (en) | 1984-12-01 |
| IT8247929A0 (en) | 1982-03-05 |
| PT74538B (en) | 1984-11-19 |
| DK97682A (en) | 1982-09-07 |
| EP0065082A2 (en) | 1982-11-24 |
| DD202024A5 (en) | 1983-08-24 |
| ES510181A0 (en) | 1983-04-16 |
| AU549146B2 (en) | 1986-01-16 |
| CA1178280A (en) | 1984-11-20 |
| ES8305759A1 (en) | 1983-04-16 |
| IL65178A (en) | 1986-02-28 |
| JPS57167983A (en) | 1982-10-16 |
| ZA821490B (en) | 1983-10-26 |
| FI70893C (en) | 1986-10-27 |
| PL235332A1 (en) | 1983-07-18 |
| KR830009080A (en) | 1983-12-17 |
| EP0065082B1 (en) | 1986-01-02 |
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