NO764039L - - Google Patents

Info

Publication number: NO764039L
Authority: NO; Norway
Prior art keywords: formula; hydrogen; stands; compounds; group
Prior art date: 1975-12-03

Application number

NO764039A

Other languages

English (en)

Norwegian (no)

Inventor

P Neumann

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-03

Filing date

1976-11-25

Publication date

1977-06-06

1975-12-03 Priority claimed from CH1571675A external-priority patent/CH605934A5/de

1975-12-22 Priority claimed from CH1664575A external-priority patent/CH605858A5/de

1976-11-25 Application filed by Sandoz Ag filed Critical Sandoz Ag

1977-06-06 Publication of NO764039L publication Critical patent/NO764039L/no

Links

229910052739 hydrogen Inorganic materials 0.000 claims description 24
239000001257 hydrogen Substances 0.000 claims description 24
150000001875 compounds Chemical class 0.000 claims description 21
150000002431 hydrogen Chemical class 0.000 claims description 13
125000000217 alkyl group Chemical group 0.000 claims description 12
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 11
125000004432 carbon atom Chemical group C* 0.000 claims description 11
239000002253 acid Substances 0.000 claims description 10
150000003839 salts Chemical class 0.000 claims description 9
125000003545 alkoxy group Chemical group 0.000 claims description 7
125000004414 alkyl thio group Chemical group 0.000 claims description 7
229910052736 halogen Inorganic materials 0.000 claims description 7
150000002367 halogens Chemical class 0.000 claims description 7
238000000034 method Methods 0.000 claims description 7
125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 6
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 6
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 5
239000005864 Sulphur Substances 0.000 claims description 5
125000001424 substituent group Chemical group 0.000 claims description 5
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
229910052760 oxygen Inorganic materials 0.000 claims description 3
239000001301 oxygen Substances 0.000 claims description 3
238000002360 preparation method Methods 0.000 claims description 3
238000006798 ring closing metathesis reaction Methods 0.000 claims description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 13
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 8
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
239000000243 solution Substances 0.000 description 7
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
239000002244 precipitate Substances 0.000 description 6
239000000203 mixture Substances 0.000 description 5
HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 4
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 4
239000000706 filtrate Substances 0.000 description 4
238000010992 reflux Methods 0.000 description 4
239000007858 starting material Substances 0.000 description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
-1 2-oxazolin-2-yl-amino Chemical group 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 3
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 3
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
150000007513 acids Chemical class 0.000 description 3
239000002585 base Substances 0.000 description 3
238000009835 boiling Methods 0.000 description 3
229910052801 chlorine Inorganic materials 0.000 description 3
239000000460 chlorine Substances 0.000 description 3
238000001953 recrystallisation Methods 0.000 description 3
229910052708 sodium Inorganic materials 0.000 description 3
239000011734 sodium Substances 0.000 description 3
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
235000011114 ammonium hydroxide Nutrition 0.000 description 2
239000008346 aqueous phase Substances 0.000 description 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
229910052794 bromium Inorganic materials 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
IUWFVAFJSDJKGN-UHFFFAOYSA-N n-(4-chloro-1h-indazol-5-yl)-4,5-dihydro-1,3-oxazol-2-amine Chemical compound C1=CC=2NN=CC=2C(Cl)=C1NC1=NCCO1 IUWFVAFJSDJKGN-UHFFFAOYSA-N 0.000 description 2
CEIIXWCAJZTSDA-UHFFFAOYSA-N n-(6-methyl-1h-indazol-5-yl)-4,5-dihydro-1,3-thiazol-2-amine Chemical compound CC1=CC=2NN=CC=2C=C1NC1=NCCS1 CEIIXWCAJZTSDA-UHFFFAOYSA-N 0.000 description 2
XTEGVFVZDVNBPF-UHFFFAOYSA-N naphthalene-1,5-disulfonic acid Chemical compound C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1S(O)(=O)=O XTEGVFVZDVNBPF-UHFFFAOYSA-N 0.000 description 2
150000002894 organic compounds Chemical class 0.000 description 2
KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Inorganic materials [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 2
FRASJONUBLZVQX-UHFFFAOYSA-N 1,4-naphthoquinone Chemical compound C1=CC=C2C(=O)C=CC(=O)C2=C1 FRASJONUBLZVQX-UHFFFAOYSA-N 0.000 description 1
YDTDKKULPWTHRV-UHFFFAOYSA-N 1H-indazol-3-amine Chemical class C1=CC=C2C(N)=NNC2=C1 YDTDKKULPWTHRV-UHFFFAOYSA-N 0.000 description 1
SQXFTQVMTPNQEW-UHFFFAOYSA-N 7-isothiocyanato-1-methylindazole Chemical compound C1=CC(N=C=S)=C2N(C)N=CC2=C1 SQXFTQVMTPNQEW-UHFFFAOYSA-N 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
GHVZOJONCUEWAV-UHFFFAOYSA-N [K].CCO Chemical compound [K].CCO GHVZOJONCUEWAV-UHFFFAOYSA-N 0.000 description 1
239000003513 alkali Substances 0.000 description 1
229910001854 alkali hydroxide Inorganic materials 0.000 description 1
229910052783 alkali metal Inorganic materials 0.000 description 1
150000001340 alkali metals Chemical class 0.000 description 1
229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 description 1
230000002152 alkylating effect Effects 0.000 description 1
235000019270 ammonium chloride Nutrition 0.000 description 1
150000007514 bases Chemical class 0.000 description 1
230000036772 blood pressure Effects 0.000 description 1
239000002775 capsule Substances 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
239000008298 dragée Substances 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
229910052731 fluorine Inorganic materials 0.000 description 1
239000011737 fluorine Substances 0.000 description 1
IYWCBYFJFZCCGV-UHFFFAOYSA-N formamide;hydrate Chemical compound O.NC=O IYWCBYFJFZCCGV-UHFFFAOYSA-N 0.000 description 1
239000008187 granular material Substances 0.000 description 1
239000012433 hydrogen halide Substances 0.000 description 1
229910000039 hydrogen halide Inorganic materials 0.000 description 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
239000012442 inert solvent Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
229910052740 iodine Inorganic materials 0.000 description 1
229940046892 lead acetate Drugs 0.000 description 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
239000011976 maleic acid Substances 0.000 description 1
QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
229910052753 mercury Inorganic materials 0.000 description 1
BRMYZIKAHFEUFJ-UHFFFAOYSA-L mercury diacetate Chemical compound CC(=O)O[Hg]OC(C)=O BRMYZIKAHFEUFJ-UHFFFAOYSA-L 0.000 description 1
BQPIGGFYSBELGY-UHFFFAOYSA-N mercury(2+) Chemical compound [Hg+2] BQPIGGFYSBELGY-UHFFFAOYSA-N 0.000 description 1
229940098779 methanesulfonic acid Drugs 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
230000003285 pharmacodynamic effect Effects 0.000 description 1
238000000746 purification Methods 0.000 description 1
238000007363 ring formation reaction Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000003826 tablet Substances 0.000 description 1
ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO764039A 1975-12-03 1976-11-25 NO764039L (ja)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
CH1571675A CH605934A5 (en)	1975-12-03	1975-12-03	Myotonolytic oxazolinyl- and thiazolinyl-amino-indazole derivs.
CH1664575A CH605858A5 (en)	1975-12-22	1975-12-22	Myotonolytic oxazolinyl- and thiazolinyl-amino-indazole derivs.
CH927976		1976-07-20
CH931276		1976-07-21

Publications (1)

Publication Number	Publication Date
NO764039L true NO764039L (ja)	1977-06-06

Family

ID=27429211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO764039A NO764039L (ja)	1975-12-03	1976-11-25

Country Status (20)

Country	Link
US (1)	US4086353A (ja)
JP (1)	JPS5268177A (ja)
AU (1)	AU510820B2 (ja)
BE (1)	BE848962A (ja)
CA (1)	CA1082714A (ja)
DE (1)	DE2653005A1 (ja)
DK (1)	DK528976A (ja)
ES (1)	ES453861A1 (ja)
FI (1)	FI763385A (ja)
FR (1)	FR2333504A1 (ja)
GB (1)	GB1564327A (ja)
IE (1)	IE44316B1 (ja)
IL (1)	IL51028A (ja)
NL (1)	NL7613317A (ja)
NO (1)	NO764039L (ja)
NZ (1)	NZ182779A (ja)
PH (1)	PH12642A (ja)
PT (1)	PT65918B (ja)
SE (1)	SE424553B (ja)
YU (1)	YU293876A (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4436913A (en) *	1980-09-05	1984-03-13	Siegfried Aktiengesellschaft	1H- and 2H- indazole derivatives
ES2357502T3 (es) *	2001-09-26	2011-04-27	Pfizer Italia S.R.L.	Derivados de aminoindazol activos como inhibidores de quinasa, procedimiento para su preparación y composiciones farmaceuticas que los contienen.
SE0402763D0 (sv) *	2004-11-11	2004-11-11	Astrazeneca Ab	Nitro indazole derivatives
SE0402762D0 (sv) *	2004-11-11	2004-11-11	Astrazeneca Ab	Indazole sulphonamide derivatives
US8648087B2 (en) *	2005-11-15	2014-02-11	Array Biopharma, Inc.	N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
WO2007075847A2 (en) *	2005-12-20	2007-07-05	Takeda Pharmaceutical Company Limited	Glucokinase activators
SI2178870T1 (sl) *	2007-08-17	2018-11-30	Lg Chem, Ltd.	Indolne in indazolne spojine kot inhibitor celične nekroze
US20100291533A1 (en) *	2008-01-04	2010-11-18	Soon Ha Kim	Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect
KR101404151B1 (ko) *	2011-11-25	2014-06-05	가톨릭대학교 산학협력단	안과 질환의 예방 및 치료용 약학 조성물
US10221172B2 (en)	2015-01-13	2019-03-05	Vanderbilt University	Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
WO2016115282A1 (en)	2015-01-13	2016-07-21	Vanderbilt University	Benzoisoxazole-substituted compounds as mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
WO2016123629A1 (en)	2015-01-30	2016-08-04	Vanderbilt University	Indazole and azaindazole substituted compounds as mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3759903A (en) *	1971-07-28	1973-09-18	Squibb & Sons Inc	Thiazolinyl and thiazinyl derivatives of indazoles

1976
- 1976-11-22 DE DE19762653005 patent/DE2653005A1/de not_active Withdrawn
- 1976-11-24 FI FI763385A patent/FI763385A/fi not_active Application Discontinuation
- 1976-11-24 DK DK528976A patent/DK528976A/da not_active Application Discontinuation
- 1976-11-25 SE SE7613195A patent/SE424553B/xx unknown
- 1976-11-25 NO NO764039A patent/NO764039L/no unknown
- 1976-11-26 US US05/745,303 patent/US4086353A/en not_active Expired - Lifetime
- 1976-11-30 NL NL7613317A patent/NL7613317A/xx not_active Application Discontinuation
- 1976-11-30 GB GB49834/76A patent/GB1564327A/en not_active Expired
- 1976-12-01 IE IE2637/76A patent/IE44316B1/en unknown
- 1976-12-01 JP JP51143543A patent/JPS5268177A/ja active Pending
- 1976-12-01 NZ NZ182779A patent/NZ182779A/xx unknown
- 1976-12-01 BE BE172887A patent/BE848962A/xx unknown
- 1976-12-01 PH PH19181A patent/PH12642A/en unknown
- 1976-12-01 ES ES453861A patent/ES453861A1/es not_active Expired
- 1976-12-01 IL IL51028A patent/IL51028A/xx unknown
- 1976-12-02 FR FR7636296A patent/FR2333504A1/fr active Granted
- 1976-12-02 YU YU02938/76A patent/YU293876A/xx unknown
- 1976-12-02 PT PT65918A patent/PT65918B/pt unknown
- 1976-12-02 CA CA267,015A patent/CA1082714A/en not_active Expired
- 1976-12-03 AU AU20252/76A patent/AU510820B2/en not_active Expired

Also Published As

Publication number	Publication date
IL51028A0 (en)	1977-02-28
FI763385A (ja)	1977-06-04
PH12642A (en)	1979-07-11
PT65918A (fr)	1977-01-01
AU2025276A (en)	1978-06-08
JPS5268177A (en)	1977-06-06
FR2333504A1 (fr)	1977-07-01
IE44316L (en)	1977-06-03
US4086353A (en)	1978-04-25
SE424553B (sv)	1982-07-26
SE7613195L (sv)	1977-06-04
FR2333504B1 (ja)	1980-08-29
AU510820B2 (en)	1980-07-17
DE2653005A1 (de)	1977-06-08
IL51028A (en)	1980-06-30
PT65918B (fr)	1978-07-05
CA1082714A (en)	1980-07-29
NL7613317A (nl)	1977-06-07
DK528976A (da)	1977-06-04
YU293876A (en)	1982-05-31
IE44316B1 (en)	1981-10-21
NZ182779A (en)	1979-08-31
GB1564327A (en)	1980-04-10
ES453861A1 (es)	1978-03-01
BE848962A (fr)	1977-06-01

Publication	Publication Date	Title
NO120426B (ja)	1970-10-19
SU493966A3 (ru)	1975-11-28	Способ получени производных 4-/2имидазолин-2-иламино/-2,1,3-бензотиадиазола
NO764039L (ja)	1977-06-06
US4076709A (en)	1978-02-28	Thienothiazines
NO762661L (ja)	1977-02-01
NO146096B (no)	1982-04-19	Analogifremgangsmaate ved fremstilling av thienothiazinderivater
SU557758A3 (ru)	1977-05-05	Способ получени 4-азабензимидазолов или их солей
NO136360B (ja)	1977-05-16
SU566524A3 (ru)	1977-07-25	Способ получени производных пиридо(1,2-а)-пиримидина или их солей
Zinnes et al.	1973	1, 2-Benzothiazines. 6. 3-Carbamoyl-4-hydroxy-2H-1, 2-benzothiazine 1, 1-dioxides as antiinflammatory agents
US3847934A (en)	1974-11-12	7-(imidazolinyl-(2)-amino)-indazoles
NO845169L (no)	1985-06-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater
NO124430B (ja)	1972-04-17
NO811667L (no)	1981-11-20	Fremgangsmaate ved fremstilling av substituerte pyrazinyl-1,2,4-oxadiazoler
NO803160L (no)	1978-08-07	Pyrimidin-derivater.
US3244723A (en)	1966-04-05	Certain 4-aminothiazole compounds and their preparation
NO130329B (ja)	1974-08-12
US2839529A (en)	1958-06-17	Isothiazole compounds
DK156059B (da)	1989-06-19	Analogifremgangsmaade til fremstilling af guanidinderivater
SU419028A3 (ru)	1974-03-05	Способ получения 2-
NO162156B (no)	1989-08-07	Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske tiadiazinonderivater
NO821725L (no)	1982-11-29	Fremgangsmaate for fremstilling av heterocykliske amidoxim-derivater.
US4118501A (en)	1978-10-03	Thiazolidine derivatives
NO762821L (ja)	1977-02-23
US3378592A (en)	1968-04-16	Process for the production of 3, 4-dihydroxybenzyloxyaminehydrobromide