NO305436B1 - 8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a - Google Patents
8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation aInfo
- Publication number
- NO305436B1 NO305436B1 NO944487A NO944487A NO305436B1 NO 305436 B1 NO305436 B1 NO 305436B1 NO 944487 A NO944487 A NO 944487A NO 944487 A NO944487 A NO 944487A NO 305436 B1 NO305436 B1 NO 305436B1
- Authority
- NO
- Norway
- Prior art keywords
- methyl
- preparation
- piperidylidene
- cyclohepta
- benzo
- Prior art date
Links
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09302460A ES2087818B1 (en) | 1993-11-24 | 1993-11-24 | 8-CHLORINE-11- (1 - ((5-METHYL-3-PIRIDYL) METHYL) -4-PIPERIDYLIDEN) -6,11-DIHYDRO-5H-BENZO- (5,6) CYCLOHEPTAL (1,2-B) PIRIDINE, SMOKING. |
Publications (3)
Publication Number | Publication Date |
---|---|
NO944487D0 NO944487D0 (en) | 1994-11-23 |
NO944487L NO944487L (en) | 1995-05-26 |
NO305436B1 true NO305436B1 (en) | 1999-05-31 |
Family
ID=8283716
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO944487A NO305436B1 (en) | 1993-11-24 | 1994-11-23 | 8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a |
NO2014001C NO2014001I2 (en) | 1993-11-24 | 2014-01-23 | Rupatadine fumarate |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO2014001C NO2014001I2 (en) | 1993-11-24 | 2014-01-23 | Rupatadine fumarate |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2087818B1 (en) |
NO (2) | NO305436B1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2120899B1 (en) * | 1996-10-07 | 1999-06-16 | Uriach & Cia Sa J | PROCEDURE FOR THE PREPARATION OF 8-CHLORO-6, 11-DIHYDRO-11- (1- (5-METHYL-3-PIRIDINYL) METHYL) -4-PIPERIDINYLIDENE) -5H-BENZO (5,6) CYCLOHEPTA (1, 2-B) PIRIDINE. |
WO2006114676A2 (en) * | 2005-04-27 | 2006-11-02 | Cadila Pharmaceuticals Limited | A process for the preparation of rupatadine |
CN101531654B (en) * | 2009-04-13 | 2013-07-17 | 浙江赐富医药有限公司 | Preparation method for Rupatadine |
CA2798028A1 (en) | 2010-06-30 | 2012-01-05 | J. Uriach Y Compania S.A. | Liquid formulations of rupatadine fumarate |
ES2471840T3 (en) * | 2010-06-30 | 2014-06-27 | J. Uriach Y Compa��A S.A. | Rupatadine derivative as an antihistamine agent |
CN102807562A (en) * | 2012-07-31 | 2012-12-05 | 东莞达信生物技术有限公司 | Method for preparing rupatadine and salt thereof |
CN103804357B (en) * | 2014-01-02 | 2016-03-23 | 珠海金鸿药业股份有限公司 | A kind of Rupatadine fumarate compound, its synthetic method and pharmaceutical composition thereof |
CN109734702B (en) * | 2019-03-01 | 2020-07-03 | 南京工业大学 | Method for preparing rupatadine fumarate by adopting micro-channel reaction device |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
IL98572A (en) * | 1990-06-22 | 1995-07-31 | Schering Corp | Bis-benzo or benzopyrido cyclohepta piperidene, piperidylidene and piperazine compositions an methods of use |
ES2042421B1 (en) * | 1992-05-22 | 1994-08-01 | Uriach & Cia Sa J | PROCEDURE FOR OBTAINING 8-CHLORINE-11- * 1 - * (5-METHYL-3-PIRIDIL) METHYL * -4-PIPERIDILIDEN * -6,11-DIHYDRO-5H-BENZO * 5,6 * CYCLOHEPTA * 1 , 2-B * PIRIDINE. |
-
1993
- 1993-11-24 ES ES09302460A patent/ES2087818B1/en not_active Expired - Fee Related
-
1994
- 1994-11-23 NO NO944487A patent/NO305436B1/en active Protection Beyond IP Right Term
-
2014
- 2014-01-23 NO NO2014001C patent/NO2014001I2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO944487L (en) | 1995-05-26 |
ES2087818B1 (en) | 1997-03-16 |
ES2087818A1 (en) | 1996-07-16 |
NO2014001I1 (en) | 2014-06-02 |
NO2014001I2 (en) | 2015-08-24 |
NO944487D0 (en) | 1994-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: J URIACH Y COMPANIA SA, ES |
|
MK1K | Patent expired | ||
SPCG | Granted supplementary protection certificate |
Free format text: PRODUCT NAME: RUPAFIN, 10 MG TABLETTER; REG.NO/DATE: 13-9499 2013.10.21; FIRST REG.NO/DATE: 16630 2001.07.04 Spc suppl protection certif: 2014001 Filing date: 20140123 Extension date: 20160704 |