NO2716304T3 - - Google Patents

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Publication number
NO2716304T3
NO2716304T3 NO12790050A NO12790050A NO2716304T3 NO 2716304 T3 NO2716304 T3 NO 2716304T3 NO 12790050 A NO12790050 A NO 12790050A NO 12790050 A NO12790050 A NO 12790050A NO 2716304 T3 NO2716304 T3 NO 2716304T3
Authority
NO
Norway
Application number
NO12790050A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2716304T3 publication Critical patent/NO2716304T3/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/31Combination therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/32Special delivery means, e.g. tissue-specific
NO12790050A 2011-05-23 2012-05-22 NO2716304T3 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011114946 2011-05-23
PCT/JP2012/063082 WO2012161196A1 (ja) 2011-05-23 2012-05-22 チミジル酸合成酵素に対するshRNA分子を含むリポソームおよびその用途

Publications (1)

Publication Number Publication Date
NO2716304T3 true NO2716304T3 (no) 2018-03-10

Family

ID=47217272

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12790050A NO2716304T3 (no) 2011-05-23 2012-05-22

Country Status (14)

Country Link
US (1) US20120301537A1 (no)
EP (1) EP2716304B1 (no)
JP (1) JP5941460B2 (no)
CN (1) CN103561775B (no)
DK (1) DK2716304T3 (no)
ES (1) ES2653923T3 (no)
HK (1) HK1190325A1 (no)
HR (1) HRP20171919T1 (no)
HU (1) HUE037803T2 (no)
NO (1) NO2716304T3 (no)
PL (1) PL2716304T3 (no)
PT (1) PT2716304T (no)
TW (1) TWI442927B (no)
WO (1) WO2012161196A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6049712B2 (ja) 2011-07-08 2016-12-21 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill 抗癌治療及び画像化並びに骨障害治療のための金属ビスホスホネートナノ粒子
US20140255471A1 (en) 2013-03-11 2014-09-11 Wake Forest University Health Sciences Method of treating brain tumors
HUE040425T2 (hu) 2013-04-30 2019-03-28 Delta Fly Pharma Inc Liposzóma topikális adagoláshoz és alkalmazása
JP6590802B2 (ja) * 2013-11-06 2019-10-16 ザ ユニバーシティ オブ シカゴThe University Of Chicago 化学療法用薬剤、核酸及び光増感剤の送達又は共送達のためのナノスケール輸送体
RU2016138020A (ru) * 2014-02-26 2018-03-29 Этрис Гмбх Композиции для введения phk в желудочно-кишечный тракт
ES2809460T3 (es) * 2014-10-30 2021-03-04 Delta Fly Pharma Inc Nuevo método de producción de lipoplejo para administración local y fármaco antitumoral que utiliza lipoplejo
JP7090034B2 (ja) 2016-05-20 2022-06-23 ザ ユニバーシティ オブ シカゴ 化学療法、標的療法、光線力学療法、免疫療法及びそれらの任意の組み合わせのためのナノ粒子
WO2018136002A1 (en) * 2017-01-18 2018-07-26 Temasek Life Sciences Laboratory Limited Hyperstabilized liposomes increase targeting of mitotic cells
WO2019012107A1 (en) * 2017-07-13 2019-01-17 Danmarks Tekniske Universitet CATIONIC LIPOSOMES
WO2019028250A1 (en) 2017-08-02 2019-02-07 The University Of Chicago NOMOGENEOUS ORGANOMETALLIC ORGANOMETRIC ORGANOMETRIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF
JP6297737B1 (ja) 2017-09-25 2018-03-20 ジェイ−ネットワーク,インコーポレイテッド 正に帯電した荷電ニオソームの調製方法及び荷電ニオソーム
CN114557964B (zh) * 2022-03-17 2024-03-12 西安艾领克生物科技有限公司 一种可载rna的阳离子梭型柔性脂质体及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202846B2 (en) * 2000-03-16 2012-06-19 Cold Spring Harbor Laboratory Methods and compositions for RNA interference
JP4543188B2 (ja) * 2004-03-10 2010-09-15 学校法人日本医科大学 ヒトチミジル酸合成酵素に対するRNAiとして作用するRNA配列
CA2604441A1 (en) * 2005-04-12 2006-10-19 Intradigm Corporation Composition and methods of rnai therapeutics for treatment of cancer and other neovascularization diseases
CA2649630C (en) * 2006-04-20 2016-04-05 Silence Therapeutics Ag Lipoplex formulations for specific delivery to vascular endothelium
WO2008035461A1 (fr) * 2006-09-22 2008-03-27 Taiho Pharmaceutical Co., Ltd. Chimiothérapie adjuvante post-opératoire pour un cancer gastrique
AU2009238175C1 (en) * 2008-04-15 2023-11-30 Arbutus Biopharma Corporation Novel lipid formulations for nucleic acid delivery
US8927207B2 (en) * 2008-06-05 2015-01-06 Research Foundation Of State University Of New York miRNAs as therapeutic targets in cancer
ES2599153T3 (es) * 2009-03-31 2017-01-31 Delta-Fly Pharma, Inc. Molécula de ARNi para la timidilato sintasa y uso de la misma
JP5446781B2 (ja) 2009-11-26 2014-03-19 トヨタ自動車株式会社 左右独立駆動車両の駆動ユニット冷却装置

Also Published As

Publication number Publication date
PT2716304T (pt) 2018-01-03
EP2716304A1 (en) 2014-04-09
US20120301537A1 (en) 2012-11-29
HK1190325A1 (zh) 2014-07-04
EP2716304A4 (en) 2014-10-29
TW201300113A (zh) 2013-01-01
TWI442927B (zh) 2014-07-01
HUE037803T2 (hu) 2018-09-28
PL2716304T3 (pl) 2018-03-30
EP2716304B1 (en) 2017-10-11
CN103561775B (zh) 2016-08-17
WO2012161196A1 (ja) 2012-11-29
JPWO2012161196A1 (ja) 2014-07-31
ES2653923T3 (es) 2018-02-09
CN103561775A (zh) 2014-02-05
JP5941460B2 (ja) 2016-06-29
HRP20171919T1 (hr) 2018-02-09
DK2716304T3 (da) 2017-11-27

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