NO20161568A1 - A new drug delivery system for treatment of cancer - Google Patents

A new drug delivery system for treatment of cancer

Info

Publication number
NO20161568A1
NO20161568A1 NO20161568A NO20161568A NO20161568A1 NO 20161568 A1 NO20161568 A1 NO 20161568A1 NO 20161568 A NO20161568 A NO 20161568A NO 20161568 A NO20161568 A NO 20161568A NO 20161568 A1 NO20161568 A1 NO 20161568A1
Authority
NO
Norway
Prior art keywords
cancer
treatment
delivery system
drug delivery
new drug
Prior art date
Application number
NO20161568A
Other languages
Norwegian (no)
Other versions
NO342271B1 (en
Inventor
Per Stenstad
Yrr Mørch
Heidi Johnsen
Rune Hansen
Ruth Schmid
Original Assignee
Sintef Tto As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sintef Tto As filed Critical Sintef Tto As
Priority to NO20161568A priority Critical patent/NO342271B1/en
Priority to CN201780073657.2A priority patent/CN110022860A/en
Priority to PCT/EP2017/074798 priority patent/WO2018060437A1/en
Priority to CA3040016A priority patent/CA3040016A1/en
Priority to JP2019517040A priority patent/JP2019529488A/en
Priority to US16/338,152 priority patent/US20200023073A1/en
Priority to EP17784222.6A priority patent/EP3518900A1/en
Publication of NO20161568A1 publication Critical patent/NO20161568A1/en
Publication of NO342271B1 publication Critical patent/NO342271B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20161568A 2016-09-29 2016-09-29 A new drug delivery system for treatment of cancer NO342271B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
NO20161568A NO342271B1 (en) 2016-09-29 2016-09-29 A new drug delivery system for treatment of cancer
CN201780073657.2A CN110022860A (en) 2016-09-29 2017-09-29 For treating the new drug delivery system of disease
PCT/EP2017/074798 WO2018060437A1 (en) 2016-09-29 2017-09-29 A new drug delivery system for treatment of disease
CA3040016A CA3040016A1 (en) 2016-09-29 2017-09-29 A new drug delivery system for treatment of disease
JP2019517040A JP2019529488A (en) 2016-09-29 2017-09-29 Novel drug delivery system for treating disease
US16/338,152 US20200023073A1 (en) 2016-09-29 2017-09-29 A new drug delivery system for treatment of disease
EP17784222.6A EP3518900A1 (en) 2016-09-29 2017-09-29 A new drug delivery system for treatment of disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO20161568A NO342271B1 (en) 2016-09-29 2016-09-29 A new drug delivery system for treatment of cancer

Publications (2)

Publication Number Publication Date
NO20161568A1 true NO20161568A1 (en) 2018-03-30
NO342271B1 NO342271B1 (en) 2018-04-30

Family

ID=62091609

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20161568A NO342271B1 (en) 2016-09-29 2016-09-29 A new drug delivery system for treatment of cancer

Country Status (1)

Country Link
NO (1) NO342271B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3773471A1 (en) 2018-03-27 2021-02-17 Sintef Tto As Poly (alkyl cyanoacrylate) nanoparticles for use in treatment of cancer

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1701745A1 (en) * 2003-12-22 2006-09-20 Bracco Research S.A. Gas-filled microvesicle assembly for contrast imaging
US20110200530A1 (en) * 2008-10-07 2011-08-18 Bracco Research S.A. or Bracco Suisse S.A. Targeting construct comprising anti-polymer antibody and contrast/therapeutic agents binding to the same
WO2012094541A2 (en) * 2011-01-05 2012-07-12 The Regents Of The University Of California Acoustically responsive particles with decreased cavitation threshold
EP2508207A1 (en) * 2011-03-31 2012-10-10 BioAlliance Pharma Nanoparticles loaded with chemotherapeutic antitumoral Drug
US20130183244A1 (en) * 2010-09-10 2013-07-18 The Johns Hopkins University Rapid Diffusion of Large Polymeric Nanoparticles in the Mammalian Brain
US20140212502A1 (en) * 2013-01-31 2014-07-31 National Yang-Ming University Nano- and micro-bubbles with ultrasound-triggered release and imaging functionalities
WO2014191502A1 (en) * 2013-05-28 2014-12-04 Sinvent As Process for preparing stealth nanoparticles

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1701745A1 (en) * 2003-12-22 2006-09-20 Bracco Research S.A. Gas-filled microvesicle assembly for contrast imaging
US20110200530A1 (en) * 2008-10-07 2011-08-18 Bracco Research S.A. or Bracco Suisse S.A. Targeting construct comprising anti-polymer antibody and contrast/therapeutic agents binding to the same
US20130183244A1 (en) * 2010-09-10 2013-07-18 The Johns Hopkins University Rapid Diffusion of Large Polymeric Nanoparticles in the Mammalian Brain
WO2012094541A2 (en) * 2011-01-05 2012-07-12 The Regents Of The University Of California Acoustically responsive particles with decreased cavitation threshold
EP2508207A1 (en) * 2011-03-31 2012-10-10 BioAlliance Pharma Nanoparticles loaded with chemotherapeutic antitumoral Drug
US20140212502A1 (en) * 2013-01-31 2014-07-31 National Yang-Ming University Nano- and micro-bubbles with ultrasound-triggered release and imaging functionalities
WO2014191502A1 (en) * 2013-05-28 2014-12-04 Sinvent As Process for preparing stealth nanoparticles

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
Baghirov, Habib, et al. Focused ultrasound-mediated transport of poly(alkyl) cyanoacrylate nanoparticles across the blood-brain barrier in a melanoma brain metastasis model. Cancer Research, (2016) Vol. 76, No. 14, Supp. Supplement. Abstract Number: 2073. Meeting Info: 107th Annual Meeting of the American Association for Cancer Research, AACR 2016. New Orleans, LA, United States. 16 Apr 2016-20 Apr 2016. ISSN: 1538-7445, Dated: 01.01.0001 *
Chaudhari K. R., et al. Targeting effiency and biodistribution of zoledronate conjugated docetaxel loaded PBCA nanoparticles for bone metastasis. Adv. Funct. Mater. 2012, 22, 4101-4114., Dated: 01.01.0001 *
De Cock, Ine, et al. Sonoprinting and the importance of microbuble loading for the ultrasound mediated cellular delivery of nanoparticles. Biomaterials, 1 Mar 2016 Vol. 83, pp. 294-307. ISSN: 0142-9612; E-ISSN: 1878-5905., Dated: 01.01.0001 *
Hansen, Rune; Stenstad, Per; Morch, Yrr. Ultrasound mediated delivery of a novel nanoparticle microbubble platform. Cancer Research, (15 Apr 2013) Vol. 73, No. 8, Supp. SUPPL. 1. Abstract Number: 5618. Meeting Info: 104th Annual Meeting of the American Association for Cancer Research, AACR 2013. Washington, DC, United States. 06 Apr 2013-10 Apr 2013. ISSN: 0008-5472 DIGITAL OBJECT ID: 10.1158/1538-7445.AM2013-5618., Dated: 01.01.0001 *
Liu, Zhe et al. Iron oxide nanoparticle-containing microbubble composites as contrast agents for MR and ultrasound dual-modality imaging, Biomaterials (2011.05.05) vol. 32. no. 26. pp. 6155-6163., Dated: 01.01.0001 *
Moon, Hyungwon, et al. Multifunctional theranostic contrast agent for photoacoustics- and ultrasound-based tumor diagnosis and ultrasound-stimulated local tumor therapy. Journal of Controlled Release, 28 Nov 2015 Vol. 218, pp. 63-71. ISSN: 0168-3659; E-ISSN: 1873-4995, Dated: 01.01.0001 *
Morch, Yrr et al. Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery. Contrast Media and Molecular Imaging, (September/October 2015) Vol. 10, No. 5, pp. 356-366. ISSN: 1555-4309; E-ISSN: 1555-4317, Dated: 01.01.0001 *
Wang, Jiayu, et al. A novel microbubble capable of ultrasound -triggered release of drug -loaded nanoparticles. Journal of Biomedical Nanotechnology, (March 2016) Vol. 12, No. 3, pp. 516-524. ISSN: 1550-7033; E-ISSN: 1550-7041, Dated: 01.01.0001 *
Zhang, Yu et al.Preparation, characterization and biocompatability of poly(ethylene glycol)-poly(n-butyl cyanoacrylate) nanocapsules with oil core via miniemulsion polymerization. European Polymer Journal 44 (2008) 1654-1661, Dated: 01.01.0001 *

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