NO20090780L - Human Glp-1 mimetistoff, sammensetninger, fremgangsmater og anvendelser - Google Patents
Human Glp-1 mimetistoff, sammensetninger, fremgangsmater og anvendelserInfo
- Publication number
- NO20090780L NO20090780L NO20090780A NO20090780A NO20090780L NO 20090780 L NO20090780 L NO 20090780L NO 20090780 A NO20090780 A NO 20090780A NO 20090780 A NO20090780 A NO 20090780A NO 20090780 L NO20090780 L NO 20090780L
- Authority
- NO
- Norway
- Prior art keywords
- mimetic
- methods
- glp
- compositions
- applications
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 101100337060 Caenorhabditis elegans glp-1 gene Proteins 0.000 title 1
- 101001032756 Rattus norvegicus Granzyme-like protein 1 Proteins 0.000 abstract 3
- 241000699660 Mus musculus Species 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
- Plant Pathology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
Abstract
Foreliggende oppfinnelse angår minst ett forbedret, humant GLP-I-mimetistoff eller spesifisert del eller variant som inkluderer isolerte nukleinsyrer som koder minst ett GLP-I-mimetistoff eller spesifisert del eller variant, GLP-I-mimetistoff eller spesifisert del eller varianter, vektorer, vertsceller, transgene mus eller planter og fremgangsmåter for fremstilling og anvendelse derav som inkluderer terapeutiske sammensetninger, fremgangsmåter og innretninger.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83170406P | 2006-07-18 | 2006-07-18 | |
PCT/US2007/073752 WO2008011446A2 (en) | 2006-07-18 | 2007-07-18 | Human glp-1 mimetibodies, compositions, methods and uses |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090780L true NO20090780L (no) | 2009-04-03 |
Family
ID=38596585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090780A NO20090780L (no) | 2006-07-18 | 2009-02-18 | Human Glp-1 mimetistoff, sammensetninger, fremgangsmater og anvendelser |
Country Status (18)
Country | Link |
---|---|
US (2) | US8071103B2 (no) |
EP (1) | EP2049567A2 (no) |
JP (1) | JP2010500868A (no) |
KR (1) | KR20090039787A (no) |
CN (1) | CN101535341A (no) |
AR (1) | AR061930A1 (no) |
AU (1) | AU2007275294A1 (no) |
BR (1) | BRPI0714334A2 (no) |
CA (1) | CA2658286A1 (no) |
CR (1) | CR10619A (no) |
EA (1) | EA200970131A1 (no) |
EC (1) | ECSP099079A (no) |
MX (1) | MX2009000748A (no) |
NO (1) | NO20090780L (no) |
TW (1) | TW200821386A (no) |
UY (1) | UY30494A1 (no) |
WO (1) | WO2008011446A2 (no) |
ZA (1) | ZA200901132B (no) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2298378T3 (es) * | 2001-06-28 | 2008-05-16 | Novo Nordisk A/S | Formulacion estable de glp-1 modificado. |
MY149546A (en) | 2007-11-02 | 2013-09-13 | Novartis Ag | Improved nogo-a binding molecules and pharmaceutical use tereof |
CA2727147A1 (en) * | 2008-06-17 | 2009-12-23 | Otsuka Chemical Co., Ltd. | Glycosylated glp-1 peptide |
JO2870B1 (en) | 2008-11-13 | 2015-03-15 | ميرك شارب اند دوهم كورب | Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes |
SI2373681T1 (sl) | 2008-12-10 | 2017-05-31 | Glaxosmithkline Llc Corporation Service Company | Farmacevtski sestavki albiglutida |
WO2010096394A2 (en) | 2009-02-17 | 2010-08-26 | Redwood Biosciences, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
MX2011012043A (es) * | 2009-05-13 | 2012-03-29 | Protein Delivery Solutions Llc | Sistema farmaceutico para suministro transmembrana. |
RU2550508C2 (ru) | 2009-09-02 | 2015-05-10 | Мерк Шарп И Доум Корп. | Аминотетрагидропираны в качестве ингибиторов дипептидилпептидазы-iv для лечения или предупреждения диабета |
EP2538783B1 (en) | 2010-02-22 | 2016-06-01 | Merck Sharp & Dohme Corp. | Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
US8426186B2 (en) | 2010-04-16 | 2013-04-23 | Centocor Ortho Biotech Inc. | Engineered potato virus A nuclear inclusion protein |
JP2013525491A (ja) * | 2010-05-04 | 2013-06-20 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 心血管障害を治療または予防し心血管保護を提供する方法 |
WO2011146358A1 (en) | 2010-05-21 | 2011-11-24 | Merck Sharp & Dohme Corp. | Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
RU2606016C2 (ru) | 2011-01-14 | 2017-01-10 | Редвуд Байосайнс, Инк. | Меченые альдегидом полипептиды иммуноглобулина и способы их применения |
JP2015519309A (ja) | 2012-04-16 | 2015-07-09 | カネック ファーマ インコーポレイテッド | Ptp−1bインヒビター前駆体としての縮合芳香族ホスホナート誘導体 |
CN103204944B (zh) * | 2013-03-26 | 2014-05-28 | 江苏健德生物药业有限公司 | 用于治疗糖尿病的长效免疫融合蛋白 |
CN109071634A (zh) | 2016-04-26 | 2018-12-21 | R.P.谢勒技术有限责任公司 | 抗体偶联物及其制备和使用方法 |
WO2019036859A1 (zh) * | 2017-08-21 | 2019-02-28 | 中国科学院动物研究所 | 分泌glp-1及其衍生物的蛋白表达***及其制备方法和用途 |
PE20211202A1 (es) | 2017-08-24 | 2021-07-05 | Novo Nordisk As | Composiciones de glp-1 y sus usos |
TWI639987B (zh) * | 2017-10-11 | 2018-11-01 | 奇美醫療財團法人奇美醫院 | 具有位置感知的穿刺輔助教學裝置 |
TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
US11713345B2 (en) * | 2018-10-22 | 2023-08-01 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (GLP1)-growth differentiation factor 15 (GDF15) fusion proteins and uses thereof |
WO2021144476A1 (en) | 2020-02-18 | 2021-07-22 | Novo Nordisk A/S | Pharmaceutical formulations |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5118666A (en) | 1986-05-05 | 1992-06-02 | The General Hospital Corporation | Insulinotropic hormone |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
US5545618A (en) | 1990-01-24 | 1996-08-13 | Buckley; Douglas I. | GLP-1 analogs useful for diabetes treatment |
US5705483A (en) | 1993-12-09 | 1998-01-06 | Eli Lilly And Company | Glucagon-like insulinotropic peptides, compositions and methods |
US5512549A (en) | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
US5723125A (en) | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
CA2468374C (en) | 1996-08-30 | 2010-12-21 | Novo-Nordisk A/S | Glp-1 derivatives |
US6849719B2 (en) * | 1997-09-17 | 2005-02-01 | Human Genome Sciences, Inc. | Antibody to an IL-17 receptor like protein |
JP2000319297A (ja) * | 1999-03-30 | 2000-11-21 | Noguchi Inst | 酵素的に安定な複合糖ペプチドの調製法 |
SI1180121T1 (en) | 1999-05-17 | 2004-04-30 | Conjuchem, Inc. | Long lasting insulinotropic peptides |
ATE424413T1 (de) * | 2000-06-16 | 2009-03-15 | Lilly Co Eli | Analoge des glucagon-ähnlichen peptids-1 |
ES2311560T3 (es) | 2000-12-07 | 2009-02-16 | Eli Lilly And Company | Proteinas de fusion glp-1. |
CN1363654A (zh) | 2001-07-19 | 2002-08-14 | 上海华谊生物技术有限公司 | 生产促胰岛素分泌肽glp-1(7-36)的基因工程菌以及生产glp-1(7-36)的方法 |
EP1575499A2 (en) | 2002-06-28 | 2005-09-21 | Centocor, Inc. | Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses |
AU2003272970B2 (en) * | 2002-10-11 | 2009-05-28 | Sanwa Kagaku Kenkyusho Co. Ltd. | GLP-1 derivatives and transmicosal absorption preparations thereof |
WO2005005604A2 (en) | 2003-06-30 | 2005-01-20 | Centocor, Inc. | Engineered anti-target immunoglobulin derived proteins, compositions, methods and uses |
EA011583B1 (ru) * | 2004-03-31 | 2009-04-28 | Сентокор, Инк. | Миметические антитела glp-1 человека, композиции, способы и применения |
-
2007
- 2007-07-18 EP EP07799669A patent/EP2049567A2/en not_active Withdrawn
- 2007-07-18 WO PCT/US2007/073752 patent/WO2008011446A2/en active Application Filing
- 2007-07-18 BR BRPI0714334-6A patent/BRPI0714334A2/pt not_active IP Right Cessation
- 2007-07-18 CA CA002658286A patent/CA2658286A1/en not_active Abandoned
- 2007-07-18 US US11/779,316 patent/US8071103B2/en not_active Expired - Fee Related
- 2007-07-18 JP JP2009520970A patent/JP2010500868A/ja active Pending
- 2007-07-18 US US12/305,034 patent/US20090325873A1/en not_active Abandoned
- 2007-07-18 EA EA200970131A patent/EA200970131A1/ru unknown
- 2007-07-18 AR ARP070103214A patent/AR061930A1/es unknown
- 2007-07-18 AU AU2007275294A patent/AU2007275294A1/en not_active Abandoned
- 2007-07-18 KR KR1020097003122A patent/KR20090039787A/ko not_active Application Discontinuation
- 2007-07-18 CN CNA2007800342628A patent/CN101535341A/zh active Pending
- 2007-07-18 TW TW096126255A patent/TW200821386A/zh unknown
- 2007-07-18 MX MX2009000748A patent/MX2009000748A/es unknown
- 2007-07-19 UY UY30494A patent/UY30494A1/es unknown
-
2009
- 2009-01-19 EC EC2009009079A patent/ECSP099079A/es unknown
- 2009-02-17 ZA ZA200901132A patent/ZA200901132B/xx unknown
- 2009-02-18 CR CR10619A patent/CR10619A/es not_active Application Discontinuation
- 2009-02-18 NO NO20090780A patent/NO20090780L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2658286A1 (en) | 2008-01-24 |
US20090325873A1 (en) | 2009-12-31 |
BRPI0714334A2 (pt) | 2013-05-14 |
CN101535341A (zh) | 2009-09-16 |
AR061930A1 (es) | 2008-10-01 |
CR10619A (es) | 2009-06-04 |
EA200970131A1 (ru) | 2009-08-28 |
JP2010500868A (ja) | 2010-01-14 |
ZA200901132B (en) | 2010-10-27 |
KR20090039787A (ko) | 2009-04-22 |
US8071103B2 (en) | 2011-12-06 |
US20080044411A1 (en) | 2008-02-21 |
WO2008011446A3 (en) | 2008-09-18 |
TW200821386A (en) | 2008-05-16 |
UY30494A1 (es) | 2008-01-31 |
ECSP099079A (es) | 2009-02-27 |
EP2049567A2 (en) | 2009-04-22 |
MX2009000748A (es) | 2009-03-31 |
WO2008011446A2 (en) | 2008-01-24 |
AU2007275294A1 (en) | 2008-01-24 |
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