NO20082656L - N-sulfamoyl-N'-benzopyranpiperidiner som inhibitorer av karbonsyreanhydraser - Google Patents

N-sulfamoyl-N'-benzopyranpiperidiner som inhibitorer av karbonsyreanhydraser

Info

Publication number
NO20082656L
NO20082656L NO20082656A NO20082656A NO20082656L NO 20082656 L NO20082656 L NO 20082656L NO 20082656 A NO20082656 A NO 20082656A NO 20082656 A NO20082656 A NO 20082656A NO 20082656 L NO20082656 L NO 20082656L
Authority
NO
Norway
Prior art keywords
sulfamoyl
benzopyran
piperidines
inhibitors
carboxylic acid
Prior art date
Application number
NO20082656A
Other languages
English (en)
Inventor
Jochen Antel
Harald Waldeck
Uwe Schoen
Peter-Colin Gregory
Michael Wurl
Michael Firnges
Dania Reiche
Uwe Reinecker
Holger Sann
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of NO20082656L publication Critical patent/NO20082656L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Den foreliggende oppfinnelse vedrører nye N-sulfamoyl-N'-benzopyranpiperidiner med generell formel (I) og deres fysiologisk akseptable syreaddisjonssalter, farmasøytiske preparater som omfatter dem, fremgangsmåter for deres fremstilling, og deres anvendelse til profylakse og/eller behandling og/eller forebyggelse og/eller inhibering av glaukom, epilepsi, bipolare forstyrrelser, migrene, neuropatisk smerte, overvekt, sukkersyke av type II, metabolsk syndrom, alkoholavhengighet og/eller kreft, og deres ledsagende og/eller sekundære sykdommer eller tilstander.
NO20082656A 2005-11-14 2008-06-13 N-sulfamoyl-N'-benzopyranpiperidiner som inhibitorer av karbonsyreanhydraser NO20082656L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05110724 2005-11-14
PCT/EP2006/068416 WO2007054580A1 (en) 2005-11-14 2006-11-14 N-sulfamoyl-n’-benzopyranpiperidines as inhbitors of carbonic anhydrases

Publications (1)

Publication Number Publication Date
NO20082656L true NO20082656L (no) 2008-08-13

Family

ID=35788569

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082656A NO20082656L (no) 2005-11-14 2008-06-13 N-sulfamoyl-N'-benzopyranpiperidiner som inhibitorer av karbonsyreanhydraser

Country Status (17)

Country Link
EP (1) EP1951725B1 (no)
JP (1) JP2009515928A (no)
KR (1) KR20080068099A (no)
CN (1) CN101309923A (no)
AT (1) ATE486876T1 (no)
AU (1) AU2006313725A1 (no)
BR (1) BRPI0618539A2 (no)
CA (1) CA2629864A1 (no)
DE (1) DE602006018053D1 (no)
ES (1) ES2356841T3 (no)
NO (1) NO20082656L (no)
PL (1) PL1951725T3 (no)
PT (1) PT1951725E (no)
RU (1) RU2008123395A (no)
UA (1) UA94596C2 (no)
WO (1) WO2007054580A1 (no)
ZA (1) ZA200803809B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2106260T3 (no) * 2007-01-25 2018-05-05
MX2019006920A (es) * 2016-12-14 2019-11-28 89Bio Ltd Derivados de la espiropiperidina.
CN110872302B (zh) * 2018-08-31 2022-09-27 沈阳中化农药化工研发有限公司 含嘧啶的螺环类化合物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2189634A1 (en) * 1994-05-06 1995-11-16 John J. Baldwin Combinatorial dihydrobenzopyran library
WO2004092179A1 (ja) * 2003-04-14 2004-10-28 Nippon Soda Co. Ltd. スピロ誘導体、製造法および抗酸化薬
JP2005119987A (ja) * 2003-10-15 2005-05-12 Ajinomoto Co Inc アシルスルホンアミド誘導体

Also Published As

Publication number Publication date
PT1951725E (pt) 2011-01-14
KR20080068099A (ko) 2008-07-22
JP2009515928A (ja) 2009-04-16
WO2007054580A1 (en) 2007-05-18
ATE486876T1 (de) 2010-11-15
CN101309923A (zh) 2008-11-19
EP1951725A1 (en) 2008-08-06
BRPI0618539A2 (pt) 2011-09-06
PL1951725T3 (pl) 2011-04-29
DE602006018053D1 (de) 2010-12-16
UA94596C2 (ru) 2011-05-25
EP1951725B1 (en) 2010-11-03
CA2629864A1 (en) 2007-05-18
ES2356841T3 (es) 2011-04-13
AU2006313725A1 (en) 2007-05-18
ZA200803809B (en) 2009-10-28
RU2008123395A (ru) 2009-12-27

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