NO20074679L - Adjuvanssammensetning omfattende aluminiumforfat og 3D-MPL - Google Patents

Adjuvanssammensetning omfattende aluminiumforfat og 3D-MPL

Info

Publication number
NO20074679L
NO20074679L NO20074679A NO20074679A NO20074679L NO 20074679 L NO20074679 L NO 20074679L NO 20074679 A NO20074679 A NO 20074679A NO 20074679 A NO20074679 A NO 20074679A NO 20074679 L NO20074679 L NO 20074679L
Authority
NO
Norway
Prior art keywords
adjuvant
mpl
adjuvant composition
aluminum scaffold
deasylated
Prior art date
Application number
NO20074679A
Other languages
English (en)
Inventor
Derek O'hagan
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Publication of NO20074679L publication Critical patent/NO20074679L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

En immunogen sammensetning omfattende: (i) et antigen; (ii) en aluminiumfiosfiat adjuvans; og (iii) en 3-0-deasylert monofiosfioiyl lipid A adjuvans. Komponent (ii) og (iii) kan også bli anvendt som et atskilt adjuvanssystem. En rekke trekk ved sammensetningene er beskrevet, inkludert at minst 50% av 3-0-deasylert monofiosfioiyl lipid A adjuvans adsorberes til aluminiumfiosfiat adjuvansen. Adjuvansblandingen er spesielt anvendbar med hepatitt B overflate antigen.
NO20074679A 2005-02-16 2007-09-13 Adjuvanssammensetning omfattende aluminiumforfat og 3D-MPL NO20074679L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65374105P 2005-02-16 2005-02-16
PCT/GB2006/000557 WO2006087563A2 (en) 2005-02-16 2006-02-16 Adjuvant composition comprising aluminium phosphate and 3d-mpl

Publications (1)

Publication Number Publication Date
NO20074679L true NO20074679L (no) 2007-09-13

Family

ID=36916823

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074679A NO20074679L (no) 2005-02-16 2007-09-13 Adjuvanssammensetning omfattende aluminiumforfat og 3D-MPL

Country Status (18)

Country Link
US (1) US20090214592A1 (no)
EP (1) EP1850871A2 (no)
JP (1) JP2008530195A (no)
KR (1) KR20070110513A (no)
CN (1) CN101146551A (no)
AP (1) AP2007004151A0 (no)
AU (1) AU2006215419B2 (no)
BE (1) BE1016991A6 (no)
BR (1) BRPI0608430A2 (no)
CA (1) CA2598079A1 (no)
EA (1) EA012212B1 (no)
IL (1) IL185346A0 (no)
MX (1) MX2007009961A (no)
NO (1) NO20074679L (no)
NZ (1) NZ560930A (no)
SG (1) SG160328A1 (no)
WO (1) WO2006087563A2 (no)
ZA (1) ZA200707089B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ565512A (en) * 2005-08-02 2011-08-26 Novartis Vaccines & Diagnostic Reducing interference between oil-containing adjuvants and surfactant-containing antigens
EP1862176A1 (de) * 2006-05-31 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
EP1862177A1 (de) * 2006-06-01 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
EP2066344B2 (en) * 2006-09-07 2016-06-29 GlaxoSmithKline Biologicals S.A. Inactivated Poliovirus combination vaccine
US20120058149A1 (en) * 2009-03-05 2012-03-08 Mccloskey Jenny Colleen Treatment of infection
CN102526724B (zh) * 2011-01-14 2015-07-22 四川大学 氢氧化铝凝胶-多糖复合免疫佐剂及其制备方法和用途
AU2012279154A1 (en) * 2011-07-01 2014-02-20 The Regents Of The University Of California Herpes virus vaccine and methods of use
CN103330936B (zh) * 2013-07-18 2016-01-27 北京民海生物科技有限公司 一种磷酸铝佐剂原位法制备乙肝疫苗的方法
RU2016141621A (ru) * 2014-03-25 2018-04-25 Зэ Гавермент Оф Зэ Юнайтед Стэйтс Оф Америка Эс Репрезентед Бай Зэ Секретари Оф Зэ Арми Способы усиления эффективности иммуностимуляции адсорбированных на соли алюминия вакцин

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Publication number Priority date Publication date Assignee Title
US4707542A (en) * 1983-08-22 1987-11-17 Merck & Co., Inc. Immunogenic HbsAg derived from transformed yeast
GB8508685D0 (en) * 1985-04-03 1985-05-09 Minor P D Peptides
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5084282A (en) * 1990-08-16 1992-01-28 J.C. Steele & Sons Apparatus for forming bricks having a textured edge
DE59100033D1 (de) * 1991-04-26 1993-03-04 Lingl Anlagenbau Verfahren und vorrichtung zum kerben eines tonstrangstueckes.
US6620414B2 (en) * 1992-03-27 2003-09-16 Smithkline Beecham Biologicals (S.A.) Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A
WO1994021292A1 (en) * 1993-03-23 1994-09-29 Smithkline Beecham Biologicals (S.A.) Vaccine compositions containing 3-o deacylated monophosphoryl lipid a
US6488934B1 (en) * 1995-02-25 2002-12-03 Smithkline Beecham Biologicals S.A. Hepatitis B vaccine
GB9503863D0 (en) * 1995-02-25 1995-04-19 Smithkline Beecham Biolog Vaccine compositions
US20010053365A1 (en) * 1995-04-25 2001-12-20 Smithkline Beecham Biologicals S.A. Vaccines
GB9718901D0 (en) * 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
EP2266604A3 (en) * 1998-10-16 2011-05-11 GlaxoSmithKline Biologicals S.A. Adjuvant systems and vaccines
GB9822714D0 (en) * 1998-10-16 1998-12-09 Smithkline Beecham Sa Vaccines
GB9921146D0 (en) * 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition
US7030094B2 (en) * 2002-02-04 2006-04-18 Corixa Corporation Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and QS-21

Also Published As

Publication number Publication date
US20090214592A1 (en) 2009-08-27
AU2006215419B2 (en) 2012-03-08
EP1850871A2 (en) 2007-11-07
EA012212B1 (ru) 2009-08-28
CN101146551A (zh) 2008-03-19
WO2006087563A2 (en) 2006-08-24
AU2006215419A1 (en) 2006-08-24
ZA200707089B (en) 2008-11-26
EA200701743A1 (ru) 2008-02-28
WO2006087563A3 (en) 2007-03-15
BRPI0608430A2 (pt) 2009-12-29
AP2007004151A0 (en) 2007-10-31
JP2008530195A (ja) 2008-08-07
SG160328A1 (en) 2010-04-29
BE1016991A6 (fr) 2007-11-06
NZ560930A (en) 2011-06-30
IL185346A0 (en) 2008-02-09
KR20070110513A (ko) 2007-11-19
CA2598079A1 (en) 2006-08-24
MX2007009961A (es) 2008-01-29

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