NO20072206L - Fremgangsmate for a undersoke Alzheimers sykdom og diagnostisk reagens - Google Patents
Fremgangsmate for a undersoke Alzheimers sykdom og diagnostisk reagensInfo
- Publication number
- NO20072206L NO20072206L NO20072206A NO20072206A NO20072206L NO 20072206 L NO20072206 L NO 20072206L NO 20072206 A NO20072206 A NO 20072206A NO 20072206 A NO20072206 A NO 20072206A NO 20072206 L NO20072206 L NO 20072206L
- Authority
- NO
- Norway
- Prior art keywords
- disease
- alzheimer
- amyloid
- investigating
- procedures
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
- G01N33/541—Double or second antibody, i.e. precipitating antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004314639 | 2004-10-28 | ||
JP2005052003 | 2005-02-25 | ||
PCT/JP2005/019787 WO2006046644A1 (ja) | 2004-10-28 | 2005-10-27 | アルツハイマー病の検定方法及び診断試薬 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20072206L true NO20072206L (no) | 2007-07-30 |
Family
ID=36227886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20072206A NO20072206L (no) | 2004-10-28 | 2007-04-30 | Fremgangsmate for a undersoke Alzheimers sykdom og diagnostisk reagens |
Country Status (13)
Country | Link |
---|---|
US (1) | US20080199879A1 (de) |
EP (1) | EP1813947A4 (de) |
JP (1) | JPWO2006046644A1 (de) |
KR (1) | KR20070073778A (de) |
CN (1) | CN101048662A (de) |
AU (1) | AU2005297854A1 (de) |
BR (1) | BRPI0516674A (de) |
CA (1) | CA2585148A1 (de) |
IL (1) | IL182540A0 (de) |
MX (1) | MX2007005053A (de) |
NO (1) | NO20072206L (de) |
RU (1) | RU2007119535A (de) |
WO (1) | WO2006046644A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
PT2289909E (pt) | 2005-11-30 | 2015-02-10 | Abbvie Inc | Método de rastreio, processo de purificação de globulómeros a-beta não difundíveis, anticorpos selectivos contra os referidos globulómeros a-beta não difundíveis e processo para o fabrico dos referidos anticorpos |
RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
EP2361638B1 (de) | 2005-12-12 | 2014-01-15 | AC Immune S.A. | A beta 1-42 spezifische monoklonale Antikörper mit therapeutischen Eigenschaften |
ES2409058T3 (es) * | 2006-04-13 | 2013-06-24 | Eidia Co., Ltd. | Método para someter a prueba la enfermedad de Alzheimer midiendo la tasa de degradación de beta-amiloide en sangre y reactivo de diagnóstico |
MX2009000476A (es) | 2006-07-14 | 2009-01-28 | Ac Immune Sa | Anticuerpo humanizado contra beta amiloide. |
JP4683298B2 (ja) * | 2006-08-21 | 2011-05-18 | アイシン精機株式会社 | 被検物質の免疫測定方法、及び免疫結合親和性解析の制御方法 |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
JP5930573B2 (ja) | 2007-03-01 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤の新規使用 |
WO2008128985A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thiourea derivatives as glutaminyl cyclase inhibitors |
US8048420B2 (en) * | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
WO2009016734A1 (ja) * | 2007-07-31 | 2009-02-05 | University Of Tsukuba | 軽度認知機能障害の検定方法 |
BRPI0818623A2 (pt) * | 2007-10-05 | 2017-05-23 | Ac Immune Sa | composição farmacêutica, e, métodos para reduzir a carga da placa na camada de célula de gânglio retinal de um animal, para reduzir a quantidade de placas na camada de célula de gânglio retinal de um animal, para diminuir a quantidade total de amilóide-beta solúvel na camada de célula de gânglio retinal de um animal, para prevenir, tratar e/ou aliviar os efeitos de uma doença ocular associada com anormalidades patológicas/mudanças no tecido do sistema visual, para monitorar doença ocular residual mínima associada com anormalidades patológicas/mudanças nos tecidos do sistema visual, para predizer responsividade de um paciente, e para reter ou diminuir a pressão ocular nos olhos de um animal |
ES2445590T3 (es) | 2007-10-05 | 2014-03-04 | Genentech, Inc. | Uso de anticuerpo anti-amiloide beta en enfermedades oculares |
US8445649B2 (en) * | 2007-10-29 | 2013-05-21 | Tao Health Life Pharma Co., Ltd. | Antibody and use thereof |
EP2344881A4 (de) * | 2008-09-26 | 2012-03-07 | Univ Melbourne | Biomarker für morbus alzheimer |
ES2548913T3 (es) | 2009-09-11 | 2015-10-21 | Probiodrug Ag | Derivados heterocíclicos como inhibidores de glutaminil ciclasa |
AU2010329844B2 (en) | 2009-12-11 | 2015-07-16 | Araclon Biotech, S.L. | Methods and reagents for improved detection of amyloid beta peptides |
WO2011092796A1 (ja) * | 2010-01-28 | 2011-08-04 | パナソニック株式会社 | アミロイドβ測定方法 |
EP2542549B1 (de) | 2010-03-03 | 2016-05-11 | Probiodrug AG | Glutaminylcyclase-hemmer |
EA022420B1 (ru) | 2010-03-10 | 2015-12-30 | Пробиодруг Аг | Гетероциклические ингибиторы глутаминилциклазы (qc, ec 2.3.2.5) |
ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
CA2806909C (en) | 2010-07-30 | 2019-12-17 | Ac Immune S.A. | Safe and functional humanized antibodies |
CA2808187A1 (en) | 2010-08-14 | 2012-02-23 | Abbvie Inc. | Amyloid-beta binding proteins |
US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
US20140302532A1 (en) | 2011-04-12 | 2014-10-09 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury |
EP2511296A1 (de) | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Antikörper, Kit und Verfahren zur Bestimmung von Amyloidpeptiden |
WO2012142300A2 (en) * | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury resulting from a hypoxic event |
US9541561B2 (en) | 2012-06-14 | 2017-01-10 | Electronics And Telecommunications Research Institute | Method for diagnosing Alzheimer's disease using biomaterial |
JP5991666B2 (ja) * | 2012-07-04 | 2016-09-14 | 公立大学法人大阪市立大学 | アルツハイマー病を検出する方法及びキット |
JP2016103980A (ja) * | 2013-03-08 | 2016-06-09 | パナソニックヘルスケア株式会社 | ハイブリドーマ及びモノクローナル抗体 |
US11360098B2 (en) * | 2015-09-28 | 2022-06-14 | Quest Diagnostics Investments Llc | Amyloid beta detection by mass spectrometry |
JP6875623B2 (ja) * | 2016-02-15 | 2021-05-26 | ノーベルファーマ株式会社 | 遺伝性疾患に関わるタンパク質の測定方法及び測定キット |
EP3242134A1 (de) * | 2016-05-04 | 2017-11-08 | Euroimmun Medizinische Labordiagnostika AG | Assay zur diagnose einer neurologischen krankheit |
EP3461819B1 (de) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Hemmer der glutaminylcyclase |
CN113311153B (zh) * | 2021-05-12 | 2023-05-26 | 华中科技大学 | 一种用于阿尔茨海默病诊疗一体化的多功能的纳米粒子 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0411974A1 (de) * | 1989-07-05 | 1991-02-06 | N.V. Innogenetics S.A. | Monoklonale Antikörper gegen neurofibrillisches Gewirrantigen |
US6610493B1 (en) * | 1993-06-17 | 2003-08-26 | Brigham And Women's Hospital | Screening compounds for the ability to alter the production of amyloid-β peptide |
US5786180A (en) * | 1995-02-14 | 1998-07-28 | Bayer Corporation | Monoclonal antibody 369.2B specific for β A4 peptide |
EP1270592B1 (de) * | 2001-06-12 | 2004-09-29 | Wiltfang, Jens | Monoklonaler Antikörper, mbAb 1E8, welcher für die zwei ersten N-terminalen Aminosäuren von Amyloid-beta-Peptiden spezifisch ist und dessen Verwendung zum Nachweis von Amyloid-beta Peptiden und/oder sAPPa |
EP1427439A4 (de) * | 2001-08-10 | 2004-11-17 | Merck & Co Inc | Gamma-drei-protease |
EP2292247A3 (de) * | 2002-03-05 | 2011-10-05 | Ramot at Tel Aviv University Ltd. | Immunisierende zusammensetzung und verfahren zur auslösung einer immunantwort gegen die beta-secretase-cleavage-stelle von amyloid-vorläuferprotein |
-
2005
- 2005-10-27 MX MX2007005053A patent/MX2007005053A/es unknown
- 2005-10-27 RU RU2007119535/15A patent/RU2007119535A/ru unknown
- 2005-10-27 WO PCT/JP2005/019787 patent/WO2006046644A1/ja active Application Filing
- 2005-10-27 CA CA002585148A patent/CA2585148A1/en not_active Abandoned
- 2005-10-27 EP EP05799253A patent/EP1813947A4/de not_active Withdrawn
- 2005-10-27 AU AU2005297854A patent/AU2005297854A1/en not_active Abandoned
- 2005-10-27 CN CNA2005800368046A patent/CN101048662A/zh not_active Withdrawn
- 2005-10-27 US US11/665,816 patent/US20080199879A1/en not_active Abandoned
- 2005-10-27 BR BRPI0516674-8A patent/BRPI0516674A/pt not_active Application Discontinuation
- 2005-10-27 JP JP2006543248A patent/JPWO2006046644A1/ja not_active Withdrawn
- 2005-10-27 KR KR1020077008426A patent/KR20070073778A/ko not_active Application Discontinuation
-
2007
- 2007-04-12 IL IL182540A patent/IL182540A0/en unknown
- 2007-04-30 NO NO20072206A patent/NO20072206L/no unknown
Also Published As
Publication number | Publication date |
---|---|
IL182540A0 (en) | 2007-09-20 |
EP1813947A4 (de) | 2008-06-11 |
MX2007005053A (es) | 2007-06-19 |
CA2585148A1 (en) | 2006-05-04 |
US20080199879A1 (en) | 2008-08-21 |
WO2006046644A1 (ja) | 2006-05-04 |
CN101048662A (zh) | 2007-10-03 |
JPWO2006046644A1 (ja) | 2008-05-22 |
RU2007119535A (ru) | 2008-12-10 |
AU2005297854A1 (en) | 2006-05-04 |
KR20070073778A (ko) | 2007-07-10 |
EP1813947A1 (de) | 2007-08-01 |
BRPI0516674A (pt) | 2008-09-16 |
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