NO20070820L - Oktahydropyrrolo (2,3,C)pyridin-derivanter og farmasoytisk anvendelse derav. - Google Patents
Oktahydropyrrolo (2,3,C)pyridin-derivanter og farmasoytisk anvendelse derav.Info
- Publication number
- NO20070820L NO20070820L NO20070820A NO20070820A NO20070820L NO 20070820 L NO20070820 L NO 20070820L NO 20070820 A NO20070820 A NO 20070820A NO 20070820 A NO20070820 A NO 20070820A NO 20070820 L NO20070820 L NO 20070820L
- Authority
- NO
- Norway
- Prior art keywords
- octahydropyrrolo
- diseases
- pyridine derivatives
- pharmaceutical use
- fibrosis
- Prior art date
Links
- 150000003222 pyridines Chemical class 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 208000005069 pulmonary fibrosis Diseases 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Abstract
Den foreliggende oppfinnelse vedrører oktahydropyrrolo[2,3,c]pyridin-derivater med formel (I) og anvendelse derav, spesielt for behandling og/eller profylakse av autoimmunsykdommer, inflammatoriske sykdommer, kardiovaskulære sykdommer, nevrodegenerative sykdommer, kreft, luftveisykdommer og fibrose, innbefattet multippel sclerose, artritt, emfysem, kronisk obstruktiv lungesykdom, lever- og lungefibrose.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58962104P | 2004-07-21 | 2004-07-21 | |
EP04103483 | 2004-07-21 | ||
PCT/EP2005/053501 WO2006008303A1 (en) | 2004-07-21 | 2005-07-20 | Octahydropyrrolo[2, 3, c]pyridine derivatives and pharmaceutical use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20070820L true NO20070820L (no) | 2007-02-13 |
Family
ID=34929357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20070820A NO20070820L (no) | 2004-07-21 | 2007-02-13 | Oktahydropyrrolo (2,3,C)pyridin-derivanter og farmasoytisk anvendelse derav. |
Country Status (11)
Country | Link |
---|---|
US (1) | US7932389B2 (no) |
EP (1) | EP1768979B1 (no) |
JP (1) | JP5069108B2 (no) |
AT (1) | ATE482956T1 (no) |
AU (1) | AU2005263762C1 (no) |
CA (1) | CA2572047C (no) |
DE (1) | DE602005023874D1 (no) |
ES (1) | ES2349940T3 (no) |
IL (1) | IL180681A0 (no) |
NO (1) | NO20070820L (no) |
WO (1) | WO2006008303A1 (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011528013A (ja) | 2008-07-14 | 2011-11-10 | ノバルティス アーゲー | ヒドロキサム酸系の選択的mmp−12およびmmp−13阻害剤 |
LV15384B (lv) | 2017-07-24 | 2019-05-20 | Latvijas Organiskās Sintēzes Institūts | 1-Acetil-5-nitro-4-fenil-3-pirolin-2-ons pielietošanai vēža ārstēšanā |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2748026B1 (fr) * | 1996-04-26 | 1998-06-05 | Adir | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU6228499A (en) * | 1998-10-22 | 2000-05-08 | Akzo Nobel N.V. | Tetrahydropyridopyridine derivatives and intermediates for producing the same |
AR022423A1 (es) * | 1999-01-27 | 2002-09-04 | American Cyanamid Co | Compuestos derivados de acidos 2,3,4,5-tetrahidro-1h-[1,4]benzodiazepina-3-hidroxamicos, composicion farmaceutica que los comprenden, y el uso de losmismos para la manufactura de un medicamento |
WO2001083461A1 (fr) | 2000-04-28 | 2001-11-08 | Shionogi & Co., Ltd. | Derives de thiazole et d'oxazole |
FR2821842B1 (fr) * | 2001-03-07 | 2003-05-09 | Servier Lab | Nouveaux derives d'inhibiteurs de mettalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO2003016248A2 (en) * | 2001-08-17 | 2003-02-27 | Bristol-Myers Squibb Company Patent Department | Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or tnf-$g(a) converting enzyme (tace) |
JP4160357B2 (ja) * | 2001-11-13 | 2008-10-01 | 株式会社資生堂 | アザビシクロ化合物及びマトリックスメタロプロテアーゼ阻害物、皮膚外用剤 |
-
2005
- 2005-07-20 AT AT05777726T patent/ATE482956T1/de not_active IP Right Cessation
- 2005-07-20 AU AU2005263762A patent/AU2005263762C1/en not_active Ceased
- 2005-07-20 WO PCT/EP2005/053501 patent/WO2006008303A1/en active Application Filing
- 2005-07-20 JP JP2007521948A patent/JP5069108B2/ja not_active Expired - Fee Related
- 2005-07-20 CA CA2572047A patent/CA2572047C/en not_active Expired - Fee Related
- 2005-07-20 US US11/658,084 patent/US7932389B2/en not_active Expired - Fee Related
- 2005-07-20 EP EP05777726A patent/EP1768979B1/en active Active
- 2005-07-20 DE DE602005023874T patent/DE602005023874D1/de active Active
- 2005-07-20 ES ES05777726T patent/ES2349940T3/es active Active
-
2007
- 2007-01-11 IL IL180681A patent/IL180681A0/en unknown
- 2007-02-13 NO NO20070820A patent/NO20070820L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP5069108B2 (ja) | 2012-11-07 |
CA2572047A1 (en) | 2006-01-26 |
ES2349940T3 (es) | 2011-01-13 |
IL180681A0 (en) | 2007-06-03 |
JP2008506752A (ja) | 2008-03-06 |
EP1768979A1 (en) | 2007-04-04 |
DE602005023874D1 (de) | 2010-11-11 |
AU2005263762A1 (en) | 2006-01-26 |
EP1768979B1 (en) | 2010-09-29 |
AU2005263762C1 (en) | 2012-03-01 |
US20080146806A1 (en) | 2008-06-19 |
AU2005263762B2 (en) | 2011-08-25 |
US7932389B2 (en) | 2011-04-26 |
WO2006008303A1 (en) | 2006-01-26 |
CA2572047C (en) | 2014-04-08 |
ATE482956T1 (de) | 2010-10-15 |
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Legal Events
Date | Code | Title | Description |
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CREP | Change of representative |
Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS |
|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |