NO20032482D0 - Compounds specific for adenosine A1, A2A and A <N> 3 receptor, and use thereof - Google Patents

Compounds specific for adenosine A1, A2A and A <N> 3 receptor, and use thereof

Info

Publication number: NO20032482D0
Authority: NO; Norway
Prior art keywords: adenosine; receptor; compounds specific; compounds; specific
Prior art date: 2000-12-01

Application number

NO20032482A

Other languages

Norwegian (no)

Other versions

NO327207B1 (en

NO20032482L (en

Inventor

Arlindo Lucas Castelhano

Bryan Mckibben

David J Witter

Original Assignee

Osi Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-01

Filing date

2003-06-02

Publication date

2003-06-02

2000-12-01 Priority claimed from US09/728,616 external-priority patent/US7160890B2/en

2000-12-01 Priority claimed from US09/728,607 external-priority patent/US6664252B2/en

2000-12-01 Priority claimed from US09/728,316 external-priority patent/US6680322B2/en

2003-06-02 Application filed by Osi Pharm Inc filed Critical Osi Pharm Inc

2003-06-02 Publication of NO20032482D0 publication Critical patent/NO20032482D0/en

2003-07-28 Publication of NO20032482L publication Critical patent/NO20032482L/en

2009-05-11 Publication of NO327207B1 publication Critical patent/NO327207B1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hematology (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Immunology (AREA)
Psychology (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20032482A 2000-12-01 2003-06-02 Compounds specific for adenosine A1, A2A and A3 receptor as well as their use in the preparation of drugs and methods for the preparation of the compounds NO327207B1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US09/728,616 US7160890B2 (en)	1999-12-02	2000-12-01	Compounds specific to adenosine A3 receptor and uses thereof
US09/728,607 US6664252B2 (en)	1999-12-02	2000-12-01	4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof
US09/728,316 US6680322B2 (en)	1999-12-02	2000-12-01	Compounds specific to adenosine A1 receptors and uses thereof
PCT/US2001/045280 WO2002057267A1 (en)	2000-12-01	2001-11-30	Compounds specific to adenosine a1, a2a, and a3 receptor and uses thereof

Publications (3)

Publication Number	Publication Date
NO20032482D0 true NO20032482D0 (en)	2003-06-02
NO20032482L NO20032482L (en)	2003-07-28
NO327207B1 NO327207B1 (en)	2009-05-11

Family

ID=27419112

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20032482A NO327207B1 (en)	2000-12-01	2003-06-02	Compounds specific for adenosine A1, A2A and A3 receptor as well as their use in the preparation of drugs and methods for the preparation of the compounds

Country Status (20)

Country	Link
EP (1)	EP1347980A4 (en)
JP (1)	JP4579497B2 (en)
CN (1)	CN1263757C (en)
AP (1)	AP1893A (en)
AU (1)	AU2002248151B2 (en)
BR (1)	BR0115847A (en)
CA (1)	CA2430577A1 (en)
CZ (1)	CZ20031831A3 (en)
EA (1)	EA007254B1 (en)
HU (1)	HUP0400692A3 (en)
IL (1)	IL155962A0 (en)
ME (1)	MEP35308A (en)
MX (1)	MXPA03004717A (en)
NO (1)	NO327207B1 (en)
NZ (1)	NZ525885A (en)
OA (1)	OA13295A (en)
PL (1)	PL363245A1 (en)
WO (1)	WO2002057267A1 (en)
YU (1)	YU42703A (en)
ZA (1)	ZA200303729B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5090531A (en) *	1990-01-10	1992-02-25	Lord Corporation	Electrophoretic fluid differential
AR020590A1 (en)	1998-06-02	2002-05-22	Cadus Pharmaceutical Corp	7-DIAZAPURINA-N-6 REPLACED, A METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND IT
US6680324B2 (en)	2000-12-01	2004-01-20	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine A1 receptors and uses thereof
DE10148883A1 (en)	2001-10-04	2003-04-10	Merck Patent Gmbh	New fused bi- or tricyclic pyrimidine derivatives, are phosphodiesterase V inhibitors useful e.g. for treating impotence, cardiovascular disorders, inflammation or tumors
CA2468673C (en) *	2001-11-30	2011-01-25	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine a1 and a3 receptors and uses thereof
EP2198867A1 (en) *	2001-12-07	2010-06-23	Vertex Pharmaceuticals, Inc.	Pyrimidine-based compounds useful as GSK-3 inhibitors
KR20040068317A (en)	2001-12-20	2004-07-30	오에스아이 파마슈티컬스, 인코포레이티드	Pyrimidine a2b selective antagonist compounds, their synthesis and use
US20030229067A1 (en)	2001-12-20	2003-12-11	Arlindo Castelhano	Pyrrolopyrimidine A2b selective antagonist compounds, their synthesis and use
AU2003270701B2 (en) *	2002-10-31	2009-11-12	Amgen Inc.	Antiinflammation agents
HUP0203976A3 (en) *	2002-11-15	2004-08-30	Sanofi Aventis	Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them
UY29177A1 (en)	2004-10-25	2006-05-31	Astex Therapeutics Ltd	SUBSTITUTED DERIVATIVES OF PURINA, PURINONA AND DEAZAPURINA, COMPOSITIONS THAT CONTAIN METHODS FOR THEIR PREPARATION AND ITS USES
MY179032A (en)	2004-10-25	2020-10-26	Cancer Research Tech Ltd	Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
EP3421471B1 (en)	2006-04-25	2021-05-26	Astex Therapeutics Limited	Purine and deazapurine derivatives as pharmaceutical compounds
US20070260203A1 (en) *	2006-05-04	2007-11-08	Allergan, Inc.	Vasoactive agent intraocular implant
TW200808819A (en) *	2006-06-19	2008-02-16	Solvay Pharm Gmbh	Use of adenosine A1 antagonists in radiocontrast media induced nephrophaty
CN101861321B (en)	2007-10-11	2013-02-06	阿斯利康(瑞典)有限公司	Pyrrolo [2, 3 -D] pyrimidin derivatives as protein kinase B inhibitors
AR070127A1 (en)	2008-01-11	2010-03-17	Novartis Ag	PIRROLO - PIRIMIDINAS AND PIRROLO -PIRIDINAS
NZ586642A (en)	2008-01-11	2012-04-27	Natco Pharma Ltd	Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents
BR112013025410A2 (en)	2011-04-01	2016-12-20	Astrazeneca Ab	therapeutic treatment
MX367640B (en)	2011-11-30	2019-08-29	Astrazeneca Ab	Combination treatment of cancer.
AU2013204533B2 (en)	2012-04-17	2017-02-02	Astrazeneca Ab	Crystalline forms
BR112014030416A2 (en) *	2012-06-07	2017-06-27	Hoffmann La Roche	compound, methods for tankyrase 1 inhibition and cancer treatment, use of a compound, composition and invention.
JP6599852B2 (en) *	2013-06-21	2019-10-30	ゼニス・エピジェネティクス・リミテッド	Novel substituted bicyclic compounds as bromodomain inhibitors
NZ714669A (en)	2013-06-21	2021-07-30	Zenith Epigenetics Ltd	Novel bicyclic bromodomain inhibitors
AU2014298051B2 (en)	2013-07-31	2018-11-15	Zenith Epigenetics Ltd.	Novel quinazolinones as bromodomain inhibitors
US10179125B2 (en)	2014-12-01	2019-01-15	Zenith Epigenetics Ltd.	Substituted pyridines as bromodomain inhibitors
WO2016087936A1 (en)	2014-12-01	2016-06-09	Zenith Epigenetics Corp.	Substituted pyridinones as bromodomain inhibitors
CN107207474B (en)	2014-12-11	2021-05-07	恒翼生物医药科技(上海)有限公司	Substituted heterocycles as bromodomain inhibitors
EP3233846A4 (en)	2014-12-17	2018-07-18	Zenith Epigenetics Ltd.	Inhibitors of bromodomains
EP3248980B1 (en) *	2015-01-20	2023-09-06	Wuxi Fortune Pharmaceutical Co., Ltd	Jak inhibitor
EP3290418B1 (en)	2015-04-29	2019-05-15	Wuxi Fortune Pharmaceutical Co., Ltd	Janus kinase (jak) inhibitors
KR102081272B1 (en)	2015-05-29	2020-02-25	우시 포춘 파마슈티컬 컴퍼니 리미티드	Janus kinase inhibitor
CN105771672B (en) *	2016-04-18	2018-03-02	天津工业大学	A kind of antipollution antibiotic aromatic polyamide reverse osmosis composite film and preparation method
WO2018161910A1 (en) *	2017-03-07	2018-09-13	广州再极医药科技有限公司	Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof
CN108017584B (en) *	2017-06-20	2021-03-23	南开大学	A3Small molecule antagonists of adenosine receptors
KR20210033444A (en) *	2018-06-04	2021-03-26	엑스사이언티아 엘티디	Pyrazolopyrimidine compounds as adenosine receptor antagonists
CN110128316B (en) *	2019-05-22	2021-08-31	北京大学深圳研究生院	Preparation method of 5-substituted beta-proline and derivatives thereof
CN110272373B (en) *	2019-07-02	2022-07-29	天津国际生物医药联合研究院	Selective adenosine A 1 Receptor antagonists and uses thereof
CN114085178A (en) *	2021-12-29	2022-02-25	苏州楚凯药业有限公司	Preparation method of 4-methyl-1-propyl-2-amino-1H-pyrrole-3-nitrile

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2895961B2 (en) *	1992-12-17	1999-05-31	フアイザー・インコーポレイテツド	Pyrrolopyrimidines as CRF antagonists
US5780450A (en) *	1995-11-21	1998-07-14	Alcon Laboratories, Inc.	Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
AR020590A1 (en) *	1998-06-02	2002-05-22	Cadus Pharmaceutical Corp	7-DIAZAPURINA-N-6 REPLACED, A METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND IT
JP2003519102A (en) *	1999-12-02	2003-06-17	オーエスアイ・ファーマスーティカルズ・インコーポレーテッド	Compounds specific for the adenosine A 1 lower, 2 A lower and 3 A lower receptors and uses thereof
CA2468673C (en) *	2001-11-30	2011-01-25	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine a1 and a3 receptors and uses thereof

2001
- 2001-11-30 EA EA200300628A patent/EA007254B1/en not_active IP Right Cessation
- 2001-11-30 CN CNB018224601A patent/CN1263757C/en not_active Expired - Fee Related
- 2001-11-30 YU YU42703A patent/YU42703A/en unknown
- 2001-11-30 HU HU0400692A patent/HUP0400692A3/en unknown
- 2001-11-30 EP EP01997029A patent/EP1347980A4/en not_active Ceased
- 2001-11-30 CA CA002430577A patent/CA2430577A1/en not_active Abandoned
- 2001-11-30 AU AU2002248151A patent/AU2002248151B2/en not_active Ceased
- 2001-11-30 NZ NZ525885A patent/NZ525885A/en active IP Right Revival
- 2001-11-30 MX MXPA03004717A patent/MXPA03004717A/en active IP Right Grant
- 2001-11-30 OA OA1200300148A patent/OA13295A/en unknown
- 2001-11-30 PL PL01363245A patent/PL363245A1/en not_active Application Discontinuation
- 2001-11-30 ME MEP-353/08A patent/MEP35308A/en unknown
- 2001-11-30 AP APAP/P/2003/002807A patent/AP1893A/en active
- 2001-11-30 JP JP2002557944A patent/JP4579497B2/en not_active Expired - Fee Related
- 2001-11-30 WO PCT/US2001/045280 patent/WO2002057267A1/en active IP Right Grant
- 2001-11-30 BR BR0115847-3A patent/BR0115847A/en not_active Application Discontinuation
- 2001-11-30 CZ CZ20031831A patent/CZ20031831A3/en unknown
- 2001-11-30 IL IL15596201A patent/IL155962A0/en unknown
2003
- 2003-05-14 ZA ZA200303729A patent/ZA200303729B/en unknown
- 2003-06-02 NO NO20032482A patent/NO327207B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EA007254B1 (en)	2006-08-25
MXPA03004717A (en)	2004-06-30
AU2002248151B2 (en)	2008-02-21
NO327207B1 (en)	2009-05-11
WO2002057267A1 (en)	2002-07-25
EA200300628A1 (en)	2003-12-25
PL363245A1 (en)	2004-11-15
HUP0400692A3 (en)	2007-09-28
JP2004517896A (en)	2004-06-17
OA13295A (en)	2007-04-13
JP4579497B2 (en)	2010-11-10
CA2430577A1 (en)	2002-07-25
MEP35308A (en)	2011-02-10
CZ20031831A3 (en)	2004-05-12
EP1347980A1 (en)	2003-10-01
HUP0400692A2 (en)	2004-07-28
BR0115847A (en)	2004-02-25
NZ525885A (en)	2005-01-28
CN1489590A (en)	2004-04-14
IL155962A0 (en)	2003-12-23
EP1347980A4 (en)	2005-02-09
CN1263757C (en)	2006-07-12
AP1893A (en)	2008-09-23
AP2003002807A0 (en)	2003-06-30
NO20032482L (en)	2003-07-28
YU42703A (en)	2006-03-03
ZA200303729B (en)	2004-05-14

Legal Events

Date	Code	Title	Description
2011-06-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO20032482L (en)	2003-07-28	Compounds specific for adenosine A1, A2A and A <N> 3 receptor, and use thereof
PT1056759E (en)	2003-01-31	2- (PURIN-9-YL) -TETRAHYDROFURANE-3,4-DIOLE DERIVATIVES
DE60007127D1 (en)	2004-01-22	N-PYRAZOLE A2A RECEPTOR AGONISTS
DE60002722D1 (en)	2003-06-18	C-PYRAZOLE A2A RECEPTOR AGONISTS
MA26878A1 (en)	2004-12-20	ADENOSINE RECEPTOR REGULATORS
NO20032735L (en)	2003-08-06	Diphenyllazetidinone derivatives, process for their preparation, drugs containing these compounds and their use
MXPA03001775A (en)	2003-06-04	Nucleoside derivatives.
DK1283839T3 (en)	2005-07-25	Adenosine A2a receptor antagonists
NO20022573D0 (en)	2002-05-30	N6 heterocyclic, 8-modified adenosine derivatives
MXPA03000078A (en)	2003-08-19	Purine derivatives.
PT1192170E (en)	2003-09-30	PROPARGILFENILETER A2A RECEPTOR AGONISTS
DE60209251D1 (en)	2006-04-20	ADENOSINE A2A RECEPTOR ANTAGONISTS
DE69934814D1 (en)	2007-02-22	NON-CIRCULAR MICRO-DRILLING
NO20032483L (en)	2003-07-30	Condensed purine derivatives as A <N> 1 <N /> - adenosine receptor antagonists
ID28539A (en)	2001-05-31	IMIDAZO (1,2A) AZINA SUBSTITUTED AS A COX-2 SELECTIVE HOLDER
AU2001247227A1 (en)	2001-09-03	2-thioether a2a receptor agonists
ATE308460T1 (en)	2005-11-15	TRANSFER MECHANISM
IT247441Y1 (en)	2002-08-22	PANIC HANDLE.
GB0010292D0 (en)	2000-06-14	A adenosine receptor agonists
IT1308149B1 (en)	2001-11-29	MODIFIED TOOL HOLDER.
ES1030353Y (en)	1996-02-01	HAND FOR MORTAR, IMPROVED.
ZA200204153B (en)	2004-11-24	Compounds specific to adenosine A3, A2A, and A3 receptor and uses thereof.
ES1040494Y (en)	2000-02-01	ISOTHERMIC BAG FOR BOTTLES.
ES1041367Y (en)	1999-11-16	DEVICE FOR HOLDING PANELS.
ES1043295Y (en)	2000-05-01	PERFECTED HANDLE MECHANISM.