NO20023577L - Fremgangsmåte for fremstilling av acetyl-amidinofenylalanyl- cykloheksylglycyl-pyridinioalaninamider - Google Patents

Fremgangsmåte for fremstilling av acetyl-amidinofenylalanyl- cykloheksylglycyl-pyridinioalaninamider

Info

Publication number: NO20023577L
Authority: NO; Norway
Prior art keywords: pyridinioalanine; amidinophenylalanyl; cyclohexylglycyl; amides; acetyl
Prior art date: 2000-01-28

Application number

NO20023577A

Other languages

English (en)

Other versions

NO20023577D0 (no

Inventor

Gerhard Breipohl

Wolfgang Holla

Heiner Jendralla

Gerhard Beck

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-28

Filing date

2002-07-26

Publication date

2002-08-28

2002-07-26 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2002-07-26 Publication of NO20023577D0 publication Critical patent/NO20023577D0/no

2002-08-28 Publication of NO20023577L publication Critical patent/NO20023577L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)

NO20023577A 2000-01-28 2002-07-26 Fremgangsmåte for fremstilling av acetyl-amidinofenylalanyl- cykloheksylglycyl-pyridinioalaninamider NO20023577L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10003586		2000-01-28
PCT/EP2001/000523 WO2001055175A2 (en)	2000-01-28	2001-01-18	Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides

Publications (2)

Publication Number	Publication Date
NO20023577D0 NO20023577D0 (no)	2002-07-26
NO20023577L true NO20023577L (no)	2002-08-28

Family

ID=7628946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20023577A NO20023577L (no)	2000-01-28	2002-07-26	Fremgangsmåte for fremstilling av acetyl-amidinofenylalanyl- cykloheksylglycyl-pyridinioalaninamider

Country Status (30)

Country	Link
US (2)	US20010031858A1 (no)
EP (1)	EP1254159B9 (no)
JP (1)	JP4778181B2 (no)
KR (1)	KR100758141B1 (no)
CN (1)	CN1176104C (no)
AR (1)	AR027246A1 (no)
AT (1)	ATE325810T1 (no)
AU (1)	AU779722B2 (no)
BR (1)	BR0107804A (no)
CA (1)	CA2398497C (no)
CZ (1)	CZ20022583A3 (no)
DE (1)	DE60119491T2 (no)
DK (1)	DK1254159T3 (no)
EE (1)	EE200200410A (no)
ES (1)	ES2262632T3 (no)
HK (1)	HK1051866A1 (no)
HR (1)	HRP20020631A2 (no)
HU (1)	HUP0301986A2 (no)
IL (2)	IL150897A0 (no)
MX (1)	MXPA02006762A (no)
NO (1)	NO20023577L (no)
NZ (1)	NZ520427A (no)
PL (1)	PL356801A1 (no)
PT (1)	PT1254159E (no)
RU (1)	RU2250212C2 (no)
SK (1)	SK10842002A3 (no)
TW (1)	TWI236481B (no)
WO (1)	WO2001055175A2 (no)
YU (1)	YU51202A (no)
ZA (1)	ZA200205990B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH695999A5 (de)	2002-02-28	2006-11-15	Wilex Ag	Verfahren zur Herstellung von 3- Amidinophenylalanin-Derivaten.
CA2632714A1 (en) *	2005-12-07	2007-06-14	Technische Universitaet Muenchen	Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
CN101774942B (zh) *	2010-01-27	2012-08-22	宁波武盛化学有限公司	制备n-乙酰基-dl-环己基甘氨酸的方法
ES2686298T3 (es) *	2010-04-20	2018-10-17	Chiral Quest, Inc.	Procedimiento enantioselectivo para alaninas beta sustituidas con cicloalquenilo
CN103249484B (zh) *	2010-11-29	2015-09-30	高砂香料工业株式会社	不对称氢化催化剂和利用它制备光学活性的羰基化合物的方法
CN115068469B (zh) *	2022-07-08	2024-02-27	深圳市小分子新药创新中心有限公司	Tigit抑制剂及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2916711A1 (de)	1979-04-25	1980-11-06	Behringwerke Ag	Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4440679A (en)	1980-03-05	1984-04-03	Cutter Laboratories, Inc.	Pasteurized therapeutically active protein compositions
US4623717A (en)	1980-03-05	1986-11-18	Miles Laboratories, Inc.	Pasteurized therapeutically active protein compositions
US5849510A (en)	1994-04-26	1998-12-15	Selectide Corporation	Factor Xa inhibitors
ZA953361B (en) *	1994-04-26	1996-01-12	Selectide Corp	Factor Xa inhibitors
AU717995B2 (en) *	1995-12-20	2000-04-06	Aventis Pharmaceuticals Inc.	Novel process for preparing N-acetyl(L)-4-cyanophenylalanine Ac-(l)-Phe(4-CN)-OH and N-Acetyl-(L)-p-amidinophenylalanine -cyclohexylglycine-beta-(3-N-methylpyridinium)-alanine Ac- (L)-pAph-Cgh-PalMe(3)-NH2
DE19856443A1 (de)	1998-12-08	2000-06-21	Centeon Pharma Gmbh	Stabilisiertes Antithrombin III-Präparat

2001
- 2001-01-18 HU HU0301986A patent/HUP0301986A2/hu unknown
- 2001-01-18 EE EEP200200410A patent/EE200200410A/xx unknown
- 2001-01-18 DK DK01911497T patent/DK1254159T3/da active
- 2001-01-18 EP EP01911497A patent/EP1254159B9/en not_active Expired - Lifetime
- 2001-01-18 ES ES01911497T patent/ES2262632T3/es not_active Expired - Lifetime
- 2001-01-18 RU RU2002123046/04A patent/RU2250212C2/ru not_active IP Right Cessation
- 2001-01-18 IL IL15089701A patent/IL150897A0/xx active IP Right Grant
- 2001-01-18 BR BR0107804-6A patent/BR0107804A/pt not_active Application Discontinuation
- 2001-01-18 PT PT01911497T patent/PT1254159E/pt unknown
- 2001-01-18 AR ARP010100225A patent/AR027246A1/es unknown
- 2001-01-18 CA CA2398497A patent/CA2398497C/en not_active Expired - Fee Related
- 2001-01-18 DE DE60119491T patent/DE60119491T2/de not_active Expired - Lifetime
- 2001-01-18 KR KR1020027009583A patent/KR100758141B1/ko not_active IP Right Cessation
- 2001-01-18 CZ CZ20022583A patent/CZ20022583A3/cs unknown
- 2001-01-18 WO PCT/EP2001/000523 patent/WO2001055175A2/en not_active Application Discontinuation
- 2001-01-18 AT AT01911497T patent/ATE325810T1/de active
- 2001-01-18 SK SK1084-2002A patent/SK10842002A3/sk unknown
- 2001-01-18 JP JP2001561027A patent/JP4778181B2/ja not_active Expired - Fee Related
- 2001-01-18 MX MXPA02006762A patent/MXPA02006762A/es active IP Right Grant
- 2001-01-18 PL PL01356801A patent/PL356801A1/xx unknown
- 2001-01-18 AU AU40516/01A patent/AU779722B2/en not_active Ceased
- 2001-01-18 CN CNB018041523A patent/CN1176104C/zh not_active Expired - Fee Related
- 2001-01-18 NZ NZ520427A patent/NZ520427A/en unknown
- 2001-01-18 YU YU51202A patent/YU51202A/sh unknown
- 2001-01-26 US US09/769,487 patent/US20010031858A1/en not_active Abandoned
- 2001-03-07 TW TW090101207A patent/TWI236481B/zh not_active IP Right Cessation
2002
- 2002-07-24 IL IL150897A patent/IL150897A/en not_active IP Right Cessation
- 2002-07-25 HR HRP20020631 patent/HRP20020631A2/hr not_active Application Discontinuation
- 2002-07-26 NO NO20023577A patent/NO20023577L/no unknown
- 2002-07-26 ZA ZA200205990A patent/ZA200205990B/en unknown
2003
- 2003-06-11 HK HK03104146A patent/HK1051866A1/xx not_active IP Right Cessation
2004
- 2004-06-17 US US10/869,076 patent/US7084250B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IL150897A0 (en)	2003-02-12
TWI236481B (en)	2005-07-21
AU4051601A (en)	2001-08-07
YU51202A (sh)	2005-11-28
CA2398497C (en)	2011-04-26
JP2003523364A (ja)	2003-08-05
EP1254159B9 (en)	2006-06-28
EE200200410A (et)	2003-12-15
CN1396928A (zh)	2003-02-12
KR20030019306A (ko)	2003-03-06
RU2002123046A (ru)	2004-01-10
WO2001055175A3 (en)	2002-02-21
US7084250B2 (en)	2006-08-01
US20010031858A1 (en)	2001-10-18
SK10842002A3 (sk)	2003-04-01
DE60119491T2 (de)	2006-11-16
RU2250212C2 (ru)	2005-04-20
PL356801A1 (en)	2004-07-12
HK1051866A1 (en)	2003-08-22
CA2398497A1 (en)	2001-08-02
HRP20020631A2 (en)	2004-12-31
JP4778181B2 (ja)	2011-09-21
BR0107804A (pt)	2002-10-22
IL150897A (en)	2008-08-07
EP1254159B1 (en)	2006-05-10
NO20023577D0 (no)	2002-07-26
NZ520427A (en)	2004-02-27
DK1254159T3 (da)	2006-09-11
DE60119491D1 (de)	2006-06-14
CN1176104C (zh)	2004-11-17
AU779722B2 (en)	2005-02-10
EP1254159A2 (en)	2002-11-06
AR027246A1 (es)	2003-03-19
CZ20022583A3 (cs)	2002-10-16
ZA200205990B (en)	2003-04-30
ES2262632T3 (es)	2006-12-01
ATE325810T1 (de)	2006-06-15
HUP0301986A2 (hu)	2003-09-29
US20040225109A1 (en)	2004-11-11
WO2001055175A2 (en)	2001-08-02
MXPA02006762A (es)	2002-10-23
KR100758141B1 (ko)	2007-09-13
PT1254159E (pt)	2006-07-31

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