NO20005838D0 - Pharmaceutical multiparticulate form with programmed and controlled release, as well as manufacture thereof - Google Patents

Pharmaceutical multiparticulate form with programmed and controlled release, as well as manufacture thereof

Info

Publication number
NO20005838D0
NO20005838D0 NO20005838A NO20005838A NO20005838D0 NO 20005838 D0 NO20005838 D0 NO 20005838D0 NO 20005838 A NO20005838 A NO 20005838A NO 20005838 A NO20005838 A NO 20005838A NO 20005838 D0 NO20005838 D0 NO 20005838D0
Authority
NO
Norway
Prior art keywords
active principle
polymer
hours
programmed
manufacture
Prior art date
Application number
NO20005838A
Other languages
Norwegian (no)
Other versions
NO330501B1 (en
NO20005838L (en
Inventor
Edouard Gendrot
Gerard Cousin
Francoise Ragot
Marie-Christine Clee-Bouvet
Original Assignee
Prographarm Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prographarm Lab filed Critical Prographarm Lab
Publication of NO20005838D0 publication Critical patent/NO20005838D0/en
Publication of NO20005838L publication Critical patent/NO20005838L/en
Publication of NO330501B1 publication Critical patent/NO330501B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

The invention concerns a mutliparticulate pharmaceutical form with delayed and timed release for starting to make the active principle available 4 to 8 hours after said pharmaceutical form has been ingested, then for gradually releasing the totality of the active principle within the following 8 to 20 hours. The invention is characterised in that it is free of organic acid and it is in the form of medicated spheroids consisting of a neutral spherical carrier comprising a first coating based on a mixture of at least a water soluble polymer and at least a water insoluble polymer wherein are uniformly distributed particles constituting an active principle, the whole comprising a second coating based on at least two independent pH polymers, having degrees of permeability with respect to different gastric and intestinal environments, optionally at least a dependent pH polymer, at least a plasticising agent and at least an inert filler distributed in said coating.
NO20005838A 1998-05-20 2000-11-17 Pharmaceutical multi-particle delayed and pulsed release form, as well as preparation thereof NO330501B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9806384A FR2778848B1 (en) 1998-05-20 1998-05-20 MULTIPARTICULATE PHARMACEUTICAL FORMULA WITH PULSED RELEASE AND ITS PREPARATION METHOD
PCT/FR1999/001201 WO1999059557A1 (en) 1998-05-20 1999-05-20 Multiparticulate pharmaceutical form with programmed and timed release and preparation method

Publications (3)

Publication Number Publication Date
NO20005838D0 true NO20005838D0 (en) 2000-11-17
NO20005838L NO20005838L (en) 2001-01-10
NO330501B1 NO330501B1 (en) 2011-05-02

Family

ID=9526556

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005838A NO330501B1 (en) 1998-05-20 2000-11-17 Pharmaceutical multi-particle delayed and pulsed release form, as well as preparation thereof

Country Status (25)

Country Link
EP (1) EP1077687B1 (en)
JP (1) JP2002515423A (en)
KR (1) KR100583065B1 (en)
CN (1) CN1186014C (en)
AT (1) ATE214598T1 (en)
AU (1) AU758299B2 (en)
BG (1) BG64764B1 (en)
BR (1) BR9910606A (en)
CA (1) CA2333188C (en)
DE (1) DE69901062T2 (en)
DK (1) DK1077687T3 (en)
ES (1) ES2173739T3 (en)
FR (1) FR2778848B1 (en)
GE (1) GEP20022750B (en)
HK (1) HK1033271A1 (en)
HU (1) HU224193B1 (en)
IL (1) IL139774A (en)
MX (1) MXPA00011364A (en)
NO (1) NO330501B1 (en)
NZ (1) NZ508392A (en)
PL (1) PL192950B1 (en)
PT (1) PT1077687E (en)
TR (1) TR200100107T2 (en)
WO (1) WO1999059557A1 (en)
ZA (1) ZA200006768B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
CA2584957C (en) 2004-10-21 2015-08-25 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
AU2013273835B2 (en) * 2005-05-02 2016-07-07 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008136016A1 (en) * 2007-05-08 2008-11-13 Medreich Limited A stable controlled release oral solid dosage form composition and a process thereof
WO2011067667A2 (en) 2009-12-02 2011-06-09 Eurand Pharmaceuticals Limited Fexofenadine microcapsules and compositions containing them
FR2999432B1 (en) 2012-12-17 2014-12-12 Ethypharm Sa ORODISPERSIBLE COMPRESSES OBTAINED BY COMPRESSION MOLDING

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2558396B2 (en) * 1990-06-28 1996-11-27 田辺製薬株式会社 Controlled release formulation
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
FR2754710B1 (en) * 1996-10-22 1998-12-31 Prographarm Lab PROCESS FOR THE PREPARATION OF A MULTIPARTICULAR PHARMACEUTICAL FORM WITH CONTROLLED RELEASE PLURISEQUENTIELLE

Also Published As

Publication number Publication date
WO1999059557A1 (en) 1999-11-25
NO330501B1 (en) 2011-05-02
IL139774A0 (en) 2002-02-10
EP1077687B1 (en) 2002-03-20
ES2173739T3 (en) 2002-10-16
DK1077687T3 (en) 2002-06-17
AU758299B2 (en) 2003-03-20
HUP0102027A3 (en) 2002-12-28
PT1077687E (en) 2002-09-30
KR20010052370A (en) 2001-06-25
NZ508392A (en) 2002-09-27
DE69901062D1 (en) 2002-04-25
BR9910606A (en) 2001-10-02
AU3830299A (en) 1999-12-06
JP2002515423A (en) 2002-05-28
MXPA00011364A (en) 2008-09-09
HUP0102027A2 (en) 2002-03-28
ZA200006768B (en) 2001-11-20
EP1077687A1 (en) 2001-02-28
FR2778848B1 (en) 2001-11-23
GEP20022750B (en) 2002-08-26
HK1033271A1 (en) 2001-08-24
TR200100107T2 (en) 2001-06-21
CN1186014C (en) 2005-01-26
CA2333188C (en) 2010-07-06
BG104963A (en) 2001-07-31
PL344314A1 (en) 2001-10-22
FR2778848A1 (en) 1999-11-26
NO20005838L (en) 2001-01-10
CA2333188A1 (en) 1999-11-25
PL192950B1 (en) 2006-12-29
ATE214598T1 (en) 2002-04-15
DE69901062T2 (en) 2002-10-31
HU224193B1 (en) 2005-06-28
IL139774A (en) 2005-09-25
KR100583065B1 (en) 2006-06-08
CN1305371A (en) 2001-07-25
BG64764B1 (en) 2006-03-31

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Legal Events

Date Code Title Description
MK1K Patent expired