NO171344C - Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator - Google Patents

Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator

Info

Publication number
NO171344C
NO171344C NO862095A NO862095A NO171344C NO 171344 C NO171344 C NO 171344C NO 862095 A NO862095 A NO 862095A NO 862095 A NO862095 A NO 862095A NO 171344 C NO171344 C NO 171344C
Authority
NO
Norway
Prior art keywords
procedure
preparation
pharmaceutical preparations
plasminogen activator
tissue plasminogen
Prior art date
Application number
NO862095A
Other languages
English (en)
Norwegian (no)
Other versions
NO171344B (no
NO862095L (no
Inventor
Michael Denis Johnston
Henry Berger
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858513358A external-priority patent/GB8513358D0/en
Priority claimed from GB858521704A external-priority patent/GB8521704D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO862095L publication Critical patent/NO862095L/no
Publication of NO171344B publication Critical patent/NO171344B/no
Publication of NO171344C publication Critical patent/NO171344C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
NO862095A 1985-05-28 1986-05-27 Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator NO171344C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858513358A GB8513358D0 (en) 1985-05-28 1985-05-28 Formulation
GB858521704A GB8521704D0 (en) 1985-08-31 1985-08-31 Formulation

Publications (3)

Publication Number Publication Date
NO862095L NO862095L (no) 1986-12-01
NO171344B NO171344B (no) 1992-11-23
NO171344C true NO171344C (no) 1993-03-03

Family

ID=26289289

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862095A NO171344C (no) 1985-05-28 1986-05-27 Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator

Country Status (22)

Country Link
US (1) US5112609A (fi)
AT (1) AT391812B (fi)
AU (1) AU569429B2 (fi)
BE (1) BE904831A (fi)
CA (1) CA1297008C (fi)
CH (1) CH664495A5 (fi)
DE (1) DE3617753A1 (fi)
DK (1) DK163174C (fi)
ES (1) ES8706443A1 (fi)
FI (1) FI85334C (fi)
FR (1) FR2593393B1 (fi)
GB (1) GB2176703B (fi)
GR (1) GR861365B (fi)
HU (1) HU200695B (fi)
IL (1) IL78937A (fi)
IT (1) IT1191925B (fi)
LU (1) LU86445A1 (fi)
NL (1) NL8601354A (fi)
NO (1) NO171344C (fi)
NZ (1) NZ216306A (fi)
PT (1) PT82647B (fi)
SE (1) SE462893B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR840004781A (ko) * 1982-05-05 1984-10-24 월터 에이치·드레거 인체의 조직 플라스미노겐 활성화제
US5185259A (en) * 1982-05-05 1993-02-09 Genentech, Inc. Truncated human tissue plasminogen activator
FI831484L (fi) * 1982-05-05 1983-11-06 Genentech Inc Plasminogen aktivator foer maenskovaevnad
AU593794B2 (en) * 1985-03-06 1990-02-22 Survival Technology Inc. Protein absorption enhancing agent
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5034225A (en) * 1985-12-17 1991-07-23 Genentech Inc. Stabilized human tissue plasminogen activator compositions
NL8701113A (nl) * 1986-05-12 1987-12-01 Wellcome Found Nieuwe farmaceutische toepassing.
US4976959A (en) * 1986-05-12 1990-12-11 Burroughs Wellcome Co. T-PA and SOD in limiting tissue damage
GB8619098D0 (en) * 1986-08-05 1986-09-17 Wellcome Found Combination
US5149533A (en) * 1987-06-04 1992-09-22 Zymogenetics, Inc. Modified t-PA with kringle-/replaced by another kringle
US5270198A (en) * 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
GB8814604D0 (en) * 1988-06-20 1988-07-27 Wellcome Found Medicaments
WO1990001334A1 (en) * 1988-08-05 1990-02-22 Codon Formulations for plasminogen activator using aspartate
GB8819607D0 (en) * 1988-08-17 1988-09-21 Wellcome Found Novel combination
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
DE3942142A1 (de) * 1989-12-20 1991-06-27 Boehringer Mannheim Gmbh Stabilisierung von glykosyliertem t-pa
GB9000629D0 (en) * 1990-01-11 1990-03-14 Porton Prod Ltd Tissue plasminogen activator
CA2129660C (en) * 1992-06-03 2005-06-28 William F. Bennett Tissue plasminogen activator glycosylation variants with improved therapeutic properties
US6139838A (en) * 1996-09-06 2000-10-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Tissue plasminogen activator medicinal composition
US7544500B2 (en) 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US20030077682A1 (en) * 2001-09-07 2003-04-24 Hung Paul Porwen Human tissue urokinase type plasminogen activator formulation
MX2010013282A (es) * 2008-06-04 2010-12-21 Talecris Biotherapeutics Inc Composicion, metodo y kit para la preparacion de plasmina.
PL2403865T3 (pl) 2009-03-03 2016-01-29 Grifols Therapeutics Inc Sposoby wytwarzania plazminogenu

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
FR2252842B1 (fi) * 1973-12-03 1977-11-04 Fabre Sa Pierre
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
US4314994A (en) * 1979-07-27 1982-02-09 Pierre Fabre S.A. Process for obtaining a plasminogen activator
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
GR79202B (fi) * 1982-05-05 1984-10-22 Genentech Inc
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
CH660742A5 (de) * 1982-10-29 1987-06-15 Mitsui Toatsu Chemicals Plasminogen-aktivator, verfahren zu seiner herstellung und diesen enthaltendes thrombolytisches agens.
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
EP0112122B1 (en) * 1982-12-14 1991-08-28 South African Inventions Development Corporation Plasminogen activator
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
DE3439980A1 (de) * 1984-11-02 1986-05-07 Behringwerke Ag, 3550 Marburg Verfahren zur reinigung sowie pasteurisierung von urokinase
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法
DE59009964D1 (de) * 1989-09-13 1996-01-25 Rieter Ag Maschf Verfahren zum Starten eines Arbeitsablaufs eines Bedienungsautomaten an einer Textilmaschine

Also Published As

Publication number Publication date
NL8601354A (nl) 1986-12-16
US5112609A (en) 1992-05-12
FI85334C (fi) 1992-04-10
NO171344B (no) 1992-11-23
BE904831A (fr) 1986-11-27
IL78937A0 (en) 1986-09-30
GB2176703A (en) 1987-01-07
LU86445A1 (fr) 1986-12-05
HUT42330A (en) 1987-07-28
DK246886A (da) 1986-11-29
IT8648064A0 (it) 1986-05-27
PT82647A (en) 1986-06-01
FI862226A0 (fi) 1986-05-27
IT1191925B (it) 1988-03-31
DE3617753A1 (de) 1986-12-04
ES555352A0 (es) 1987-07-01
FR2593393B1 (fr) 1989-06-02
AT391812B (de) 1990-12-10
SE462893B (sv) 1990-09-17
AU569429B2 (en) 1988-01-28
DK163174B (da) 1992-02-03
NO862095L (no) 1986-12-01
HU200695B (en) 1990-08-28
ATA141186A (de) 1990-06-15
GB8612781D0 (en) 1986-07-02
DE3617753C2 (fi) 1988-06-30
GR861365B (en) 1986-09-29
DK246886D0 (da) 1986-05-27
FR2593393A1 (fr) 1987-07-31
CH664495A5 (de) 1988-03-15
SE8602404D0 (sv) 1986-05-27
FI85334B (fi) 1991-12-31
SE8602404L (sv) 1986-11-29
ES8706443A1 (es) 1987-07-01
CA1297008C (en) 1992-03-10
IL78937A (en) 1990-11-29
DK163174C (da) 1992-06-22
NZ216306A (en) 1989-10-27
GB2176703B (en) 1988-12-07
FI862226A (fi) 1986-11-29
AU5796586A (en) 1986-12-04
PT82647B (pt) 1989-01-30

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