NO163899C - Fremgangsmaate for fremstilling av diisopropyletersolvatetav beclometason-17,21-dipropionat. - Google Patents

Fremgangsmaate for fremstilling av diisopropyletersolvatetav beclometason-17,21-dipropionat.

Info

Publication number
NO163899C
NO163899C NO852948A NO852948A NO163899C NO 163899 C NO163899 C NO 163899C NO 852948 A NO852948 A NO 852948A NO 852948 A NO852948 A NO 852948A NO 163899 C NO163899 C NO 163899C
Authority
NO
Norway
Prior art keywords
diisopropyleters
beclometason
dipropionate
solvates
procedure
Prior art date
Application number
NO852948A
Other languages
English (en)
Other versions
NO163899B (no
NO852948L (no
Inventor
Philip Ronald Page
William Heggie
Original Assignee
Hovione Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT7897284A external-priority patent/PT78972A/pt
Priority claimed from PT8079685A external-priority patent/PT80796B/pt
Application filed by Hovione Int Ltd filed Critical Hovione Int Ltd
Publication of NO852948L publication Critical patent/NO852948L/no
Publication of NO163899B publication Critical patent/NO163899B/no
Publication of NO163899C publication Critical patent/NO163899C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
NO852948A 1984-07-25 1985-07-24 Fremgangsmaate for fremstilling av diisopropyletersolvatetav beclometason-17,21-dipropionat. NO163899C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT7897284A PT78972A (en) 1984-07-25 1984-07-25 Preparation process of a 17,21-dipropionate beclomethasona di-isopropylic ether solution and its utilization
PT8079685A PT80796B (pt) 1985-07-11 1985-07-11 Processo para a preparacao de solvatos etoericos de beclometasona 17,21-dipropionato e utilizacao dos mesmos

Publications (3)

Publication Number Publication Date
NO852948L NO852948L (no) 1986-01-27
NO163899B NO163899B (no) 1990-04-30
NO163899C true NO163899C (no) 1990-08-08

Family

ID=26653439

Family Applications (1)

Application Number Title Priority Date Filing Date
NO852948A NO163899C (no) 1984-07-25 1985-07-24 Fremgangsmaate for fremstilling av diisopropyletersolvatetav beclometason-17,21-dipropionat.

Country Status (12)

Country Link
US (1) US4913892A (no)
EP (1) EP0172672B1 (no)
KR (1) KR880001237B1 (no)
AU (1) AU566318B2 (no)
CA (1) CA1274503A (no)
DE (1) DE3561321D1 (no)
DK (1) DK336485A (no)
HK (1) HK58789A (no)
IE (1) IE59086B1 (no)
IL (1) IL75903A (no)
NO (1) NO163899C (no)
NZ (1) NZ212877A (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
MX9304585A (es) 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
CN1245982C (zh) * 1996-05-09 2006-03-22 阿姆瑞德手术有限公司 哮喘和气道疾病的治疗
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
AU2008214205B2 (en) 2007-02-11 2014-04-24 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
EP0039369B1 (en) * 1980-05-02 1983-06-15 Schering Corporation Beclomethasone ester solvates, process for their preparation, and preparation of a formulation
GB2107715B (en) * 1981-10-19 1985-11-13 Glaxo Group Ltd Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it

Also Published As

Publication number Publication date
NO163899B (no) 1990-04-30
IL75903A0 (en) 1985-12-31
DK336485D0 (da) 1985-07-24
DK336485A (da) 1986-01-26
EP0172672B1 (en) 1988-01-07
IL75903A (en) 1989-10-31
DE3561321D1 (en) 1988-02-11
EP0172672A1 (en) 1986-02-26
KR860001122A (ko) 1986-02-22
US4913892A (en) 1990-04-03
CA1274503A (en) 1990-09-25
AU566318B2 (en) 1987-10-15
KR880001237B1 (ko) 1988-07-12
NZ212877A (en) 1988-03-30
AU4530585A (en) 1986-01-30
HK58789A (en) 1989-07-28
IE59086B1 (en) 1994-01-12
NO852948L (no) 1986-01-27

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