NO160712C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser.

Info

Publication number
NO160712C
NO160712C NO850045A NO850045A NO160712C NO 160712 C NO160712 C NO 160712C NO 850045 A NO850045 A NO 850045A NO 850045 A NO850045 A NO 850045A NO 160712 C NO160712 C NO 160712C
Authority
NO
Norway
Prior art keywords
benzotiazepine
compounds
preparation
therapeutically active
analogue procedure
Prior art date
Application number
NO850045A
Other languages
English (en)
Other versions
NO850045L (no
NO160712B (no
Inventor
Hirosada Sugihara
Kohei Nishikawa
Katsumi Ito
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1984/000119 external-priority patent/WO1985004402A1/ja
Priority claimed from PCT/JP1984/000172 external-priority patent/WO1985004657A1/ja
Priority claimed from US06/599,187 external-priority patent/US4564612A/en
Priority claimed from PCT/JP1984/000363 external-priority patent/WO1986000618A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO850045L publication Critical patent/NO850045L/no
Priority to NO871049A priority Critical patent/NO871049D0/no
Publication of NO160712B publication Critical patent/NO160712B/no
Publication of NO160712C publication Critical patent/NO160712C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO850045A 1984-03-24 1985-01-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser. NO160712C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO871049A NO871049D0 (no) 1984-03-24 1987-03-13 Kondenserte 7-leddete forbindelser og fremgangsmaate for deres fremstilling.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP1984/000119 WO1985004402A1 (en) 1984-03-24 1984-03-24 Fused 7-membered ring compounds and process for their preparation
PCT/JP1984/000172 WO1985004657A1 (en) 1984-04-06 1984-04-06 Fused 7-membered ring compounds and process for their preparation
US06/599,187 US4564612A (en) 1983-04-22 1984-04-11 Condensed, seven-membered ring compounds and their use
PCT/JP1984/000363 WO1986000618A1 (en) 1984-07-13 1984-07-13 Condensed 7-membered ring compounds and process for their preparation

Publications (3)

Publication Number Publication Date
NO850045L NO850045L (no) 1985-09-23
NO160712B NO160712B (no) 1989-02-13
NO160712C true NO160712C (no) 1989-05-24

Family

ID=27466903

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850045A NO160712C (no) 1984-03-24 1985-01-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser.

Country Status (8)

Country Link
EP (1) EP0156455A3 (no)
JP (1) JPH0215060A (no)
ES (2) ES8702389A1 (no)
FI (1) FI82465C (no)
IE (1) IE850148L (no)
IL (1) IL74004A (no)
NO (1) NO160712C (no)
PH (1) PH23261A (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657707B2 (ja) * 1987-05-25 1994-08-03 吉富製薬株式会社 ピペリジン化合物
EP0359004A1 (en) * 1988-09-05 1990-03-21 Takeda Chemical Industries, Ltd. Transdermal therapeutic composition for the treatment of hypertension
ATE107517T1 (de) * 1989-05-25 1994-07-15 Takeda Chemical Industries Ltd Transdermales therapeutisches mittel.
JPH0338583A (ja) * 1989-07-04 1991-02-19 Nippon Soda Co Ltd 1‐(4‐テトラヒドロピラニル)‐1‐ブテン‐3‐オンの製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
DE3260831D1 (en) * 1981-06-05 1984-10-31 Merck & Co Inc Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
US4564612A (en) * 1983-04-22 1986-01-14 Takeda Chemical Industries, Ltd. Condensed, seven-membered ring compounds and their use
IT1176345B (it) * 1983-06-29 1987-08-18 Mitsui Toatsu Chemicals Derivati benzotiazepinici e loro metodo di preparazione
IL72523A (en) * 1983-08-12 1988-06-30 Takeda Chemical Industries Ltd 3-amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives,their production and pharmaceutical compositions containing them
DE3426720A1 (de) * 1984-07-20 1986-01-23 Hoechst Ag, 6230 Frankfurt Benzthiazepinon- und benzthiazocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Also Published As

Publication number Publication date
IL74004A0 (en) 1985-04-30
FI851154L (fi) 1985-09-23
EP0156455A3 (en) 1987-07-22
EP0156455A2 (en) 1985-10-02
NO850045L (no) 1985-09-23
JPH0215060A (ja) 1990-01-18
FI851154A0 (fi) 1985-03-22
ES8702389A1 (es) 1987-01-01
NO160712B (no) 1989-02-13
ES557636A0 (es) 1988-02-16
IL74004A (en) 1991-12-15
FI82465C (fi) 1991-03-11
PH23261A (en) 1989-06-16
ES540548A0 (es) 1987-01-01
ES8801653A1 (es) 1988-02-16
IE850148L (en) 1985-09-22
JPH0563468B2 (no) 1993-09-10
FI82465B (fi) 1990-11-30

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