NL7805652A - PROCEDURE FOR PREPARING PHARMACEUTICAL PREPARATIONS WITH NARCOTIC ANTAGONISTIC ACTION. - Google Patents

PROCEDURE FOR PREPARING PHARMACEUTICAL PREPARATIONS WITH NARCOTIC ANTAGONISTIC ACTION.

Info

Publication number
NL7805652A
NL7805652A NL7805652A NL7805652A NL7805652A NL 7805652 A NL7805652 A NL 7805652A NL 7805652 A NL7805652 A NL 7805652A NL 7805652 A NL7805652 A NL 7805652A NL 7805652 A NL7805652 A NL 7805652A
Authority
NL
Netherlands
Prior art keywords
procedure
pharmaceutical preparations
preparing pharmaceutical
antagonistic action
narcotic antagonistic
Prior art date
Application number
NL7805652A
Other languages
Dutch (nl)
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of NL7805652A publication Critical patent/NL7805652A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL7805652A 1966-01-19 1978-05-24 PROCEDURE FOR PREPARING PHARMACEUTICAL PREPARATIONS WITH NARCOTIC ANTAGONISTIC ACTION. NL7805652A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52170866A 1966-01-19 1966-01-19
US677727A US3393197A (en) 1966-01-19 1967-10-24 Nu-substituted-14-hydroxydihydronormorphines

Publications (1)

Publication Number Publication Date
NL7805652A true NL7805652A (en) 1978-09-29

Family

ID=27060549

Family Applications (2)

Application Number Title Priority Date Filing Date
NL6618022.A NL165744C (en) 1966-01-19 1966-12-22 PROCESS FOR PREPARING 14-HYDROXY 7,8-DIHYDRONOR MORPHINE DERIVATIVES.
NL7805652A NL7805652A (en) 1966-01-19 1978-05-24 PROCEDURE FOR PREPARING PHARMACEUTICAL PREPARATIONS WITH NARCOTIC ANTAGONISTIC ACTION.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL6618022.A NL165744C (en) 1966-01-19 1966-12-22 PROCESS FOR PREPARING 14-HYDROXY 7,8-DIHYDRONOR MORPHINE DERIVATIVES.

Country Status (13)

Country Link
US (1) US3393197A (en)
AT (1) AT292206B (en)
CH (1) CH493522A (en)
DE (2) DE1670616C3 (en)
DK (1) DK115631B (en)
ES (1) ES334942A1 (en)
FR (1) FR6112M (en)
GB (1) GB1119270A (en)
IL (1) IL26896A (en)
LU (1) LU52650A1 (en)
NL (2) NL165744C (en)
NO (1) NO120368B (en)
SE (1) SE329402B (en)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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US3476757A (en) * 1966-04-18 1969-11-04 Syntex Corp Tetrahydropyranyl and tetrahydrofuranyl ethers of benzomorphans and morphanans
US4161597A (en) * 1976-12-20 1979-07-17 Research Corporation N-alkyl-14-hydroxymorphinans and derivatives
GB1587831A (en) * 1977-03-23 1981-04-08 Reckitt & Colmann Prod Ltd Morphine derivatives
GB1593191A (en) * 1977-03-23 1981-07-15 Reckitt & Colmann Prod Ltd Derivatives of morphine
US4218454A (en) * 1977-07-08 1980-08-19 Sri International N-αMethylcyclopropylmethyl derivatives of normorphine and noroodeine, and analgesic compositions and methods employing the normorphine derivatives
US4269843A (en) * 1978-05-24 1981-05-26 Sri International N-Sec-alkyl analogs of norcodeine and normorphine and analgesic compositions and methods employing the normorphine derivatives
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4236008A (en) * 1978-09-19 1980-11-25 E. I. Du Pont De Nemours And Company Fluorination of precursors for fluorine analogs of hydrocodone and oxycodone
US4241065A (en) * 1979-07-02 1980-12-23 E. I. Du Pont De Nemours And Company Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both
US4237140A (en) * 1979-05-18 1980-12-02 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetaminophen
US4282215A (en) * 1980-06-17 1981-08-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetylsalicylic acid, derivative or salt thereof
US4366159A (en) * 1981-09-08 1982-12-28 Michael Richard Magruder Nalbuphine-narcotic analgesic composition and method of producing analgesia
US4407804A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and indomethacin
US4404211A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and flurbiprofen
US4404208A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4407805A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and zomepirac
US4404209A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and sulindac
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4402962A (en) * 1982-06-30 1983-09-06 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
AU565634B2 (en) * 1982-06-30 1987-09-24 E.I. Du Pont De Nemours And Company Synergistic compositions of nalbuphine and non-narcotic analgesic compounds
US4477457A (en) * 1982-10-28 1984-10-16 E. I. Du Pont De Nemours And Company Method for inducing anorexia using nalmetrene
US4478840A (en) * 1983-10-11 1984-10-23 E. I. Du Pont De Nemours And Company Appetite suppressing compositions and methods
US4668685A (en) * 1984-07-05 1987-05-26 E.I. Du Pont De Nemours And Company Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists
CA1280695C (en) * 1985-04-29 1991-02-26 Benigno M. Sulit, Jr. Nalbuphine-local anesthetic analgesic composition and method of producing analgesia
DE4132159A1 (en) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-HYDROXY-N- (2-METHOXYETHYL) -7,8-DIHYDROMORPHINE AND -NORISOMORPHINE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DRUG
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
ES2127532T3 (en) * 1994-05-31 1999-04-16 Mallinckrodt Chemical Inc PREPARATION OF NALBUPHINE WITH LOW LEVELS OF THE EPIMERAL BETA.
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US20030138508A1 (en) * 2001-12-18 2003-07-24 Novack Gary D. Method for administering an analgesic
EP1392262A1 (en) 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
BR0205721A (en) * 2001-07-06 2003-09-30 Endo Pharmaceuticals Inc Controlled Release Oxymorphone Formulations
US8329216B2 (en) * 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
US20030129234A1 (en) * 2001-07-06 2003-07-10 Penwest Pharmaceuticals Company Methods of making sustained release formulations of oxymorphone
EP1429730A4 (en) * 2001-09-26 2010-06-16 Penwest Pharmaceuticals Compan Opioid formulations having reduced potential for abuse
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
EP1625334B9 (en) 2003-05-21 2012-07-25 Alexza Pharmaceuticals, Inc. Percussively ignited self-contained heating unit
JP2007526217A (en) * 2003-06-04 2007-09-13 アルカーメス，インコーポレイテッド Polymorphic form of naltrexone
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
AU2004322756B2 (en) 2004-08-12 2011-04-14 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
US20070093517A1 (en) * 2005-10-24 2007-04-26 Gary Newton Local anesthetic compositions
US20070212414A1 (en) * 2006-03-08 2007-09-13 Penwest Pharmaceuticals Co. Ethanol-resistant sustained release formulations
AU2007240680B2 (en) * 2006-04-21 2013-05-02 Nektar Therapeutics Stereoselective reduction of a morphinone
ES2594867T3 (en) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
AU2008231127B2 (en) * 2007-03-23 2013-05-02 SpecGx LLC Improved preparation of oxymorphone from oripavine
WO2008130553A1 (en) * 2007-04-16 2008-10-30 Mallinckrodt Inc. Novel opiate reduction utilizing catalytic hydrogen transfer reaction
US20090124650A1 (en) * 2007-06-21 2009-05-14 Endo Pharmaceuticals, Inc. Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
US8067596B2 (en) 2007-12-17 2011-11-29 Mallinckrodt Llc Processes for the production of (+)- “Nal” morphinan compounds
WO2017046814A1 (en) * 2015-09-14 2017-03-23 Rusan Pharma Limited A safe and environment friendly process for producing nalbuphine or its pharmaceutically acceptable salts thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320262A (en) * 1964-09-22 1967-05-16 Lewenstein 14 hydroxy morphine and codeine carboxymethyloximes

Also Published As

Publication number Publication date
DE1795707C3 (en) 1979-12-20
NL165744C (en) 1981-05-15
LU52650A1 (en) 1967-02-20
NL165744B (en) 1980-12-15
NL6618022A (en) 1967-07-20
ES334942A1 (en) 1968-03-01
SE329402B (en) 1970-10-12
DE1795707A1 (en) 1973-10-11
DK115631B (en) 1969-10-27
NO120368B (en) 1970-10-12
AT292206B (en) 1971-08-25
IL26896A (en) 1970-11-30
DE1670616C3 (en) 1978-06-29
DE1795707B2 (en) 1979-04-19
FR6112M (en) 1968-06-17
DE1670616A1 (en) 1970-09-10
US3393197A (en) 1968-07-16
CH493522A (en) 1970-07-15
GB1119270A (en) 1968-07-10
DE1670616B2 (en) 1977-11-10

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Legal Events

Date Code Title Description
BV The patent application has lapsed