NL7800753A - Nieuw gesubstitueerd propylamine, werkwijze voor de bereiding, alsmede toepassing daarvan. - Google Patents

Nieuw gesubstitueerd propylamine, werkwijze voor de bereiding, alsmede toepassing daarvan.

Info

Publication number
NL7800753A
NL7800753A NL7800753A NL7800753A NL7800753A NL 7800753 A NL7800753 A NL 7800753A NL 7800753 A NL7800753 A NL 7800753A NL 7800753 A NL7800753 A NL 7800753A NL 7800753 A NL7800753 A NL 7800753A
Authority
NL
Netherlands
Prior art keywords
preparation
new
substituted propylamine
propylamine
substituted
Prior art date
Application number
NL7800753A
Other languages
English (en)
Other versions
NL189258B (nl
NL189258C (nl
Original Assignee
Europ De Rech Mauvernay Sa Cen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europ De Rech Mauvernay Sa Cen filed Critical Europ De Rech Mauvernay Sa Cen
Publication of NL7800753A publication Critical patent/NL7800753A/nl
Publication of NL189258B publication Critical patent/NL189258B/nl
Application granted granted Critical
Publication of NL189258C publication Critical patent/NL189258C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7800753,A 1977-01-25 1978-01-20 Zout van 3-isobutoxy-2-pyrrolidino-n-fenyl-n-benzyl-propylamine met cardiovasculaire eigenschappen, alsmede geneesmiddel dat dit zout bevat. NL189258C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702058A FR2378024A1 (fr) 1977-01-25 1977-01-25 Nouvelle propylamine substituee, obtention et application

Publications (3)

Publication Number Publication Date
NL7800753A true NL7800753A (nl) 1978-07-27
NL189258B NL189258B (nl) 1992-09-16
NL189258C NL189258C (nl) 1993-02-16

Family

ID=9185890

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7800753,A NL189258C (nl) 1977-01-25 1978-01-20 Zout van 3-isobutoxy-2-pyrrolidino-n-fenyl-n-benzyl-propylamine met cardiovasculaire eigenschappen, alsmede geneesmiddel dat dit zout bevat.

Country Status (12)

Country Link
JP (1) JPS5392764A (nl)
AU (1) AU516479B2 (nl)
BE (1) BE863214A (nl)
CH (1) CH628889A5 (nl)
DE (1) DE2802864C2 (nl)
ES (1) ES466237A1 (nl)
FR (1) FR2378024A1 (nl)
GB (1) GB1595031A (nl)
IL (1) IL53816A0 (nl)
NL (1) NL189258C (nl)
PT (1) PT67556B (nl)
ZA (1) ZA78426B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE32715T1 (de) * 1981-12-28 1988-03-15 Carter Wallace Verfahren zur herstellung von b-((2methylpropoxy)-methyl>-n-phenyl-n-(phenylmethyl - 1-pyrrolidinethanamin.
DK156396C (da) * 1983-09-27 1990-01-08 Cerm Cent Europ Rech Mauvernay 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse
AU568704B2 (en) * 1983-11-11 1988-01-07 Akzo N.V. Ether of n-propanolamine derivative
GB8330197D0 (en) * 1983-11-11 1983-12-21 Akzo Nv Ether of n-propanolamine derivative
FR2558161B1 (fr) * 1984-01-18 1987-01-23 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino) n-furylmethyl ou n-thienylmethyl n-pyridyl propylamines, leur preparation et leur application en therapeutique
FR2558160B1 (fr) * 1984-01-18 1986-05-30 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino)-n-pyrimidinyl ou -pyrazinyl propylamines, leur preparation et leur application en therapeutique
FR2558159B1 (fr) * 1984-01-18 1986-06-13 Cerm Cent Europ Rech Mauvernay 3-alkoxy 2-(n-pyrrolidino)-n-pyridyl-n-arylmethyl-propylamines, leur preparation et leur application en therapeutique
DE3726632A1 (de) * 1987-08-11 1989-05-18 Boehringer Mannheim Gmbh 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3726633A1 (de) * 1987-08-11 1989-02-23 Boehringer Mannheim Gmbh Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
JP2678758B2 (ja) * 1988-02-16 1997-11-17 興和株式会社 新規なプロパン誘導体
WO2016098128A1 (en) * 2014-12-16 2016-06-23 Council Of Scientific & Industrial Research Process for the preparation of bepridil

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795735A (fr) * 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay Nouvelles ethylenediamines substituees a activite cardiovasculaire

Also Published As

Publication number Publication date
NL189258B (nl) 1992-09-16
PT67556B (fr) 1979-06-18
IL53816A0 (en) 1978-04-30
FR2378024A1 (fr) 1978-08-18
NL189258C (nl) 1993-02-16
CH628889A5 (en) 1982-03-31
GB1595031A (en) 1981-08-05
JPS5429493B2 (nl) 1979-09-25
BE863214A (fr) 1978-07-24
PT67556A (fr) 1978-02-01
AU516479B2 (en) 1981-06-04
JPS5392764A (en) 1978-08-15
ZA78426B (en) 1979-01-31
DE2802864A1 (de) 1978-07-27
AU3266078A (en) 1979-08-02
ES466237A1 (es) 1978-10-16
DE2802864C2 (de) 1982-12-09
FR2378024B1 (nl) 1979-05-11

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

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