NL7705630A - N-acyl gesubstitueerde benzamiden en werkwijzen voor hun bereiding en toepassing. - Google Patents
N-acyl gesubstitueerde benzamiden en werkwijzen voor hun bereiding en toepassing.Info
- Publication number
- NL7705630A NL7705630A NL7705630A NL7705630A NL7705630A NL 7705630 A NL7705630 A NL 7705630A NL 7705630 A NL7705630 A NL 7705630A NL 7705630 A NL7705630 A NL 7705630A NL 7705630 A NL7705630 A NL 7705630A
- Authority
- NL
- Netherlands
- Prior art keywords
- substituated
- benzamides
- acyl
- preparation
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2623228A DE2623228C3 (de) | 1976-05-24 | 1976-05-24 | N-Acyl-substituierte Benzamide, Verfahren zu ihrer Herstellung und Arzneimittel, enthaltend solche Benzamide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL7705630A true NL7705630A (nl) | 1977-11-28 |
| NL187437B NL187437B (nl) | 1991-05-01 |
| NL187437C NL187437C (nl) | 1991-10-01 |
Family
ID=5978871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7705630,A NL187437C (nl) | 1976-05-24 | 1977-05-23 | Werkwijze voor het bereiden van een farmaceutisch preparaat met anti-inflammatoire werking en werkwijze voor daarvoor geschikte n-acyl-4-amino-5-chloor-n-((2-diethylamino)ethyl)-2-methoxybenzamideverbindingen. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4146637A (nl) |
| AT (1) | AT348990B (nl) |
| BE (1) | BE854683A (nl) |
| CA (1) | CA1091247A (nl) |
| CH (1) | CH633259A5 (nl) |
| DE (1) | DE2623228C3 (nl) |
| FR (1) | FR2352791A1 (nl) |
| GB (1) | GB1555723A (nl) |
| NL (1) | NL187437C (nl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2730174C2 (de) * | 1977-07-04 | 1981-12-10 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Aminobenzoesäurederivate und Arzneimittel enthaltend solche Aminobenzoesäurederivate |
| US4251263A (en) * | 1979-09-04 | 1981-02-17 | Stauffer Chemical Company | N-substituted, 2-phenoxynicotinamide compounds and the herbicidal use thereof |
| ZA86171B (en) * | 1985-01-16 | 1986-08-27 | Hoffmann La Roche | Polycyclic salts |
| US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| US6100299A (en) * | 1996-03-08 | 2000-08-08 | Oxigene, Inc. | N-acetyl 3-chloroprocainamide, acid addition salts thereof, and methods of use |
| JP3933244B2 (ja) * | 1997-04-04 | 2007-06-20 | 株式会社資生堂 | アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤 |
| SE9901875D0 (sv) * | 1999-05-25 | 1999-05-25 | Astra Pharma Prod | Novel compounds |
| AU2001239725A1 (en) * | 2000-01-13 | 2001-07-24 | Tularik, Inc. | Antibacterial agents |
| WO2003087045A1 (en) * | 2002-04-09 | 2003-10-23 | 7Tm Pharma A/S | Novel methoxybenzamide compounds for use in mch receptor related disorders |
| US7351719B2 (en) * | 2002-10-31 | 2008-04-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds |
| WO2004048319A1 (en) * | 2002-11-25 | 2004-06-10 | 7Tm Pharma A/S | Novel benzamide compounds for use in mch receptor related disorders |
| US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
| US20090221703A1 (en) * | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| CA2664335C (en) * | 2006-09-20 | 2014-12-02 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
| KR101853971B1 (ko) | 2007-06-04 | 2018-05-02 | 테크필즈 인크 | 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도 |
| US8455514B2 (en) * | 2008-01-17 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-and 7-amino isoquinoline compounds and methods for making and using the same |
| US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
| BRPI0922263B1 (pt) | 2008-12-04 | 2021-08-31 | Chongxi Yu | Composição de alta penetração de um fármaco principal, e seus usos |
| ES2553827T3 (es) | 2009-05-01 | 2015-12-14 | Aerie Pharmaceuticals, Inc. | Inhibidores de mecanismo doble para el tratamiento de enfermedad |
| CN109528721B (zh) | 2013-03-15 | 2021-10-01 | 爱瑞制药公司 | 联合治疗 |
| EP3101006A1 (en) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Ror gamma (rory) modulators |
| JP6832946B2 (ja) | 2015-11-17 | 2021-02-24 | アエリエ ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤およびその中間体の調製方法 |
| US9643927B1 (en) | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
| EP3506890A1 (en) | 2016-08-31 | 2019-07-10 | Aerie Pharmaceuticals, Inc. | Ophthalmic compositions |
| SG11201908179UA (en) | 2017-03-31 | 2019-10-30 | Aerie Pharmaceuticals Inc | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
| CN111065383A (zh) | 2017-07-11 | 2020-04-24 | 沃泰克斯药物股份有限公司 | 用作钠通道调节剂的羧酰胺 |
| WO2020056345A1 (en) | 2018-09-14 | 2020-03-19 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR8120M (nl) * | 1968-12-26 | 1970-08-03 | ||
| US3898278A (en) * | 1973-04-02 | 1975-08-05 | Menarini Sas | Substituted N-phenylbenzamides |
| GB1438612A (en) * | 1974-02-08 | 1976-06-09 | Biorex Laboratories Ltd | Glycyrrhetinic acid derivatives |
-
1976
- 1976-05-24 DE DE2623228A patent/DE2623228C3/de not_active Expired
-
1977
- 1977-05-09 CH CH575477A patent/CH633259A5/de not_active IP Right Cessation
- 1977-05-16 AT AT348877A patent/AT348990B/de not_active IP Right Cessation
- 1977-05-16 BE BE177612A patent/BE854683A/xx not_active IP Right Cessation
- 1977-05-20 GB GB21342/77A patent/GB1555723A/en not_active Expired
- 1977-05-23 US US05/799,166 patent/US4146637A/en not_active Expired - Lifetime
- 1977-05-23 NL NLAANVRAGE7705630,A patent/NL187437C/nl not_active IP Right Cessation
- 1977-05-23 FR FR7715663A patent/FR2352791A1/fr active Granted
- 1977-05-24 CA CA278,971A patent/CA1091247A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4146637A (en) | 1979-03-27 |
| CA1091247A (en) | 1980-12-09 |
| DE2623228C3 (de) | 1981-09-10 |
| ATA348877A (de) | 1978-08-15 |
| NL187437C (nl) | 1991-10-01 |
| AT348990B (de) | 1979-03-12 |
| CH633259A5 (de) | 1982-11-30 |
| BE854683A (fr) | 1977-11-16 |
| DE2623228B2 (nl) | 1979-06-21 |
| FR2352791B1 (nl) | 1979-03-09 |
| FR2352791A1 (fr) | 1977-12-23 |
| DE2623228A1 (de) | 1977-12-01 |
| GB1555723A (en) | 1979-11-14 |
| NL187437B (nl) | 1991-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| V1 | Lapsed because of non-payment of the annual fee |