NL7307815A - Bredinine - antiviral agent and immunosuppressant - Google Patents
Bredinine - antiviral agent and immunosuppressantInfo
- Publication number
- NL7307815A NL7307815A NL7307815A NL7307815A NL7307815A NL 7307815 A NL7307815 A NL 7307815A NL 7307815 A NL7307815 A NL 7307815A NL 7307815 A NL7307815 A NL 7307815A NL 7307815 A NL7307815 A NL 7307815A
- Authority
- NL
- Netherlands
- Prior art keywords
- bredinine
- antiviral agent
- pref
- immunosuppressant
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The compound of formula (I) is new: (I), called bredinine, is an immunosuppressive and antiviral agent of low toxicity. It also has weak anti-microbial activity (e.g. against Candida albicans) and antitumour activity. (I) is obtd. by culturing Eupenicillium brefeldianum NRRL 5734 most pref. under submerged, aerobic conditions. The nutrient medium is conventional, temp. is 26-30 degrees C and cultivation time typically 40-70 hrs. (I) is pref. recovered from the liquid phase by absorption on a strong basic ion-exchange resin, elution with acid and opt. further purification by treatment with Sephadex DEAE A-25.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL737307815A NL154781B (en) | 1973-06-05 | 1973-06-05 | PROCEDURE FOR THE PREPARATION OF A COMPOUND WITH AN EFFICACY AGAINST VIRUS AND FOR THE PREPARATION OF A MEDICINAL PRODUCT. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL737307815A NL154781B (en) | 1973-06-05 | 1973-06-05 | PROCEDURE FOR THE PREPARATION OF A COMPOUND WITH AN EFFICACY AGAINST VIRUS AND FOR THE PREPARATION OF A MEDICINAL PRODUCT. |
Publications (2)
Publication Number | Publication Date |
---|---|
NL7307815A true NL7307815A (en) | 1974-12-09 |
NL154781B NL154781B (en) | 1977-10-17 |
Family
ID=19819015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL737307815A NL154781B (en) | 1973-06-05 | 1973-06-05 | PROCEDURE FOR THE PREPARATION OF A COMPOUND WITH AN EFFICACY AGAINST VIRUS AND FOR THE PREPARATION OF A MEDICINAL PRODUCT. |
Country Status (1)
Country | Link |
---|---|
NL (1) | NL154781B (en) |
-
1973
- 1973-06-05 NL NL737307815A patent/NL154781B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NL154781B (en) | 1977-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SNR | Assignments of patents or rights arising from examined patent applications |
Owner name: ASAHI KASEI KOGYO KABUSHIKI KAISHA |
|
NL80 | Abbreviated name of patent owner mentioned of already nullified patent |
Owner name: TOYO JOZO |
|
V4 | Lapsed because of reaching the maximum lifetime of a patent |