NL7307100A - 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride - Google Patents

1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride

Info

Publication number
NL7307100A
NL7307100A NL7307100A NL7307100A NL7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A
Authority
NL
Netherlands
Prior art keywords
dimethoxy
acetic acid
benzyloxybenzoyl
dimethylpyrogallol
sulphurylchloride
Prior art date
Application number
NL7307100A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to NL7307100A priority Critical patent/NL7307100A/en
Priority to JP4705574A priority patent/JPS5014653A/ja
Priority to FI128674A priority patent/FI128674A/fi
Publication of NL7307100A publication Critical patent/NL7307100A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cpds. of formula (I) are new: (where R = -CH(Cl)COOR" when R' = benzyl; or -CH2Cl when R' = H; R" = alkyl). (I) are intermediates in the preparation of pharmaceutically-active compounds. A soln. of 72 ml. sulphuryl chloride in 250 ml. acetic acid is added over 1 hour to a soln. of 272 g. methyl alpha-(3,5-dimethoxy-4-benzyloxybenzoyl)acetate in 510 ml. acetic acid. After stirring for 1/4 hour, 340 ml. conc. HCl are added and refluxed for 1 hour. Working up gives 164 g. of omega-chloro-3,5-dimethoxy-4-hydroxyacetophenone, m.pt. 148-150 degrees C.
NL7307100A 1973-05-22 1973-05-22 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride NL7307100A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
NL7307100A NL7307100A (en) 1973-05-22 1973-05-22 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride
JP4705574A JPS5014653A (en) 1973-05-22 1974-04-24
FI128674A FI128674A (en) 1973-05-22 1974-04-25

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7307100A NL7307100A (en) 1973-05-22 1973-05-22 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride

Publications (1)

Publication Number Publication Date
NL7307100A true NL7307100A (en) 1974-11-26

Family

ID=19818913

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7307100A NL7307100A (en) 1973-05-22 1973-05-22 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride

Country Status (3)

Country Link
JP (1) JPS5014653A (en)
FI (1) FI128674A (en)
NL (1) NL7307100A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59189200A (en) * 1983-04-11 1984-10-26 株式会社日本触媒 Method of cleaning substance surface
CZ20033394A3 (en) 2001-06-12 2005-03-16 Wellstat Therapeutics Corporation Compounds for treating metabolic disorders and process of their preparation

Also Published As

Publication number Publication date
FI128674A (en) 1974-11-23
JPS5014653A (en) 1975-02-15

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Legal Events

Date Code Title Description
BV The patent application has lapsed