NL300387I1 - Antilichaam tegen menselijke interleukine-6-receptor - Google Patents

Antilichaam tegen menselijke interleukine-6-receptor

Info

Publication number
NL300387I1
NL300387I1 NL300387C NL300387C NL300387I1 NL 300387 I1 NL300387 I1 NL 300387I1 NL 300387 C NL300387 C NL 300387C NL 300387 C NL300387 C NL 300387C NL 300387 I1 NL300387 I1 NL 300387I1
Authority
NL
Netherlands
Prior art keywords
receptor
human interleukin
antibody
antibodies
competitive
Prior art date
Application number
NL300387C
Other languages
English (en)
Original Assignee
Kishimoto T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kishimoto T filed Critical Kishimoto T
Publication of NL300387I1 publication Critical patent/NL300387I1/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NL300387C 1989-07-20 2009-04-27 Antilichaam tegen menselijke interleukine-6-receptor NL300387I1 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18601689 1989-07-20

Publications (1)

Publication Number Publication Date
NL300387I1 true NL300387I1 (nl) 2009-07-01

Family

ID=16180912

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300387C NL300387I1 (nl) 1989-07-20 2009-04-27 Antilichaam tegen menselijke interleukine-6-receptor

Country Status (10)

Country Link
EP (1) EP0409607B1 (nl)
JP (1) JP2998976B2 (nl)
KR (1) KR100214759B1 (nl)
AT (1) ATE144713T1 (nl)
CA (1) CA2021594C (nl)
DE (2) DE69029015T2 (nl)
ES (1) ES2093017T3 (nl)
HK (1) HK49497A (nl)
NL (1) NL300387I1 (nl)
SG (1) SG42954A1 (nl)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05236966A (ja) * 1991-04-25 1993-09-17 Chugai Pharmaceut Co Ltd ヒトインターロイキン−6レセプターに対するマウスモノクローナル抗体の可変領域をコードするdna
AU668349B2 (en) * 1991-04-25 1996-05-02 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human interleukin 6 receptor
FR2694767B1 (fr) * 1992-08-13 1994-10-21 Innotherapie Lab Sa Anticorps monoclonaux anti-IL6R, et leurs applications.
WO1995009873A1 (en) * 1993-10-06 1995-04-13 Board Of Regents, The University Of Texas System A monoclonal anti-human il-6 receptor antibody
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor
US5856098A (en) * 1994-09-14 1999-01-05 Progenitor, Inc. Detection of a leptin receptor variant
US6355237B1 (en) 1994-09-14 2002-03-12 Progenitor, Inc. Methods for using the obese gene and its gene product to stimulate hematopoietic development
US5763211A (en) * 1994-09-14 1998-06-09 Progenitor, Inc. Isolated nucleic acid encoding Hu-B1.219, a novel human hematopoietin
US5912123A (en) * 1994-09-14 1999-06-15 Progenitor, Inc. Detection of the leptin receptor in reproductive organs and methods for regulating reproductive biology
US6451523B1 (en) 1994-09-14 2002-09-17 Interneuron Pharmaceuticals, Inc. Detection of a leptin receptor variant and methods for regulating obesity
ES2384222T3 (es) * 1994-10-07 2012-07-02 Chugai Seiyaku Kabushiki Kaisha Inhibición del crecimiento anómalo de células sinoviales utilizando un antagonista de IL-6 como principio activo
WO1996012503A1 (fr) * 1994-10-21 1996-05-02 Chugai Seiyaku Kabushiki Kaisha Remede contre des maladies provoquees par la production d'il-6
JP3458512B2 (ja) * 1995-02-23 2003-10-20 東ソー株式会社 骨密度の変動推定方法又は骨そしょう症の診断方法及びこれに用いる試薬キット
AU1833197A (en) * 1996-01-18 1997-08-11 Progenitor, Inc. Detection of a leptin receptor variant and methods for regulating obesity
JP3471195B2 (ja) 1996-06-27 2003-11-25 中外製薬株式会社 ナイトロジェンマスタード系抗癌剤と組合わせて使用するための骨髄腫治療剤
ES2477996T3 (es) 2000-08-11 2014-07-18 Chugai Seiyaku Kabushiki Kaisha Preparaciones estabilizadas que contienen un anticuerpo
EP1334731B1 (en) 2000-10-25 2008-02-27 Chugai Seiyaku Kabushiki Kaisha Preventives or remedies for psoriasis containing as the active ingredient il-6 antagonist
UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
SI1690550T1 (sl) 2003-10-17 2012-12-31 Chugai Seiyaku Kabushiki Kaisha Terapevtska sredstva za mezoteliom
RU2450830C2 (ru) 2005-10-21 2012-05-20 Чугаи Сейяку Кабусики Кайся Средства для лечения кардиопатии
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
KR20080084818A (ko) 2005-11-25 2008-09-19 각고호우징 게이오기주크 전립선암 치료제
CA2637917C (en) 2006-01-27 2015-11-24 Keio University Therapeutic agents for diseases involving choroidal neovascularization
JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
US8080248B2 (en) 2006-06-02 2011-12-20 Regeneron Pharmaceuticals, Inc. Method of treating rheumatoid arthritis with an IL-6R antibody
CN102585002A (zh) 2006-06-02 2012-07-18 瑞泽恩制药公司 人il-6受体的高亲和力抗体
AU2007285695B2 (en) * 2006-08-18 2012-05-24 Ablynx N.V. Amino acid sequences directed against IL-6R and polypeptides comprising the same for the treatment of diseases and disorders associated with IL-6-mediated signalling
CN101528778A (zh) * 2006-08-18 2009-09-09 埃博灵克斯股份有限公司 用于治疗与il-6-介导的信号传导相关的疾病和病症的针对il-6r的氨基酸序列以及包括其的多肽
CA2672386A1 (en) * 2006-12-13 2008-06-19 Ablynx N.V. Polypeptides specific for complexes involved in receptor-mediated signaling, such as the il-6/il-6 receptor complex
EP2174667B1 (en) 2007-07-26 2017-01-04 Osaka University Agent for treatment of ophthalmia containing interleukin-6 receptor inhibitor as active ingredient
US8529895B2 (en) 2007-10-02 2013-09-10 Chugai Seiyaku Kabushiki Kaisha Method for suppressing the development of graft-versus-host-disease by administering interleukin 6 receptor antibodies
EP2297202B1 (en) 2008-05-13 2016-01-13 NovImmune SA Anti-il-6/il-6r antibodies and methods of use thereof
EP2305306B1 (en) 2008-06-05 2016-02-10 National Cancer Center Neuroinvasion inhibitor
WO2010115995A2 (en) 2009-04-10 2010-10-14 Ablynx Nv Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
EP2417163B1 (en) 2009-04-10 2019-02-27 Ablynx N.V. Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
WO2011013786A1 (ja) 2009-07-31 2011-02-03 Maeda Shin 癌の転移抑制剤
PL2493922T3 (pl) 2009-10-26 2017-07-31 F.Hoffmann-La Roche Ag Sposób wytwarzania glikozylowanych immunoglobulin
JO3417B1 (ar) 2010-01-08 2019-10-20 Regeneron Pharma الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
EP2578231B1 (en) 2010-05-28 2022-10-26 Chugai Seiyaku Kabushiki Kaisha Antitumor t cell response enhancer
WO2013041722A1 (en) 2011-09-23 2013-03-28 Ablynx Nv Prolonged inhibition of interleukin-6 mediated signaling
TWI589299B (zh) 2011-10-11 2017-07-01 再生元醫藥公司 用於治療類風濕性關節炎之組成物及其使用方法
EP3009518B1 (en) 2013-06-11 2020-08-12 National Center of Neurology and Psychiatry Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (rrms) patient, and method for determining applicability of novel therapy
BR112015032960B1 (pt) 2013-07-04 2021-01-05 F. Hoffmann-La Roche Ag imunoensaio suprimido por interferência para detectar anticorpos anti-fármaco em amostras de soro
DE202014010499U1 (de) 2013-12-17 2015-10-20 Kymab Limited Targeting von humaner PCSK9 zur Cholesterinbehandlung
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US10118967B2 (en) 2014-10-21 2018-11-06 Ablynx N.V. Methods for treating rheumatoid arthritis by administering IL-6 receptor antibodies
WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法
US20210363238A1 (en) 2018-01-31 2021-11-25 Motokazu Kato Therapeutic agent for asthma containing il-6 inhibitor
CN114206442A (zh) 2019-01-31 2022-03-18 赛诺菲生物技术公司 用于治疗幼年特发性关节炎的抗il-6受体抗体
US11897951B2 (en) 2020-12-18 2024-02-13 Ablynx N.V. Polypeptides comprising immunoglobulin single variable domains targeting IL-6 and TNF-α

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2598666B2 (ja) * 1987-10-19 1997-04-09 忠三 岸本 抗ヒトbcdfモノクローナル抗体
CA1341152C (en) * 1988-01-22 2000-12-12 Tadamitsu Kishimoto Receptor protein for human b cell stimulatory factor-2

Also Published As

Publication number Publication date
EP0409607A3 (en) 1991-06-12
JP2998976B2 (ja) 2000-01-17
EP0409607B1 (en) 1996-10-30
DE69029015D1 (de) 1996-12-05
HK49497A (en) 1997-04-25
ES2093017T3 (es) 1996-12-16
JPH03139293A (ja) 1991-06-13
SG42954A1 (en) 1997-10-17
DE69029015T2 (de) 1998-01-22
ATE144713T1 (de) 1996-11-15
EP0409607A2 (en) 1991-01-23
CA2021594C (en) 2002-01-08
KR100214759B1 (ko) 1999-08-02
DE122009000023I1 (de) 2009-08-06
CA2021594A1 (en) 1991-01-21
DE122009000023I2 (de) 2010-12-16

Similar Documents

Publication Publication Date Title
NL300387I1 (nl) Antilichaam tegen menselijke interleukine-6-receptor
DK666389A (da) Monoklonalt antistof
NO980030D0 (no) Monoklonale antistoffer som binder CD40-L
DE68914244D1 (de) Monoklonaler Antikörper.
KR900702007A (ko) T세포 항원 수용체의 지어부위와 반응하는 단클론항체
EP0597829A4 (en) NEW MONOCLONAL ANTIBODY DRESSES AGAINST A NEW ANTIGEN ASSOCIATED WITH HUMAN TUMORS.
DE3885355D1 (de) Monoklonale Antikörper.
ES2058490T3 (es) Metodo de reducir respuestas de inmunoglobulina e.
DK188185A (da) Monoklonalt antistof
NO177311C (no) Anti-fucosylceramid monoklonalt antistoff
DK717888A (da) Monoklonale antistoffer
DE3850993D1 (de) Monoklonaler Antikörper spezifisch gegen humane Pankreas-Phospholipase-A2.
DK69690A (da) Humane anti-rh(d) monoklonale antistoffer
DK474189A (da) Monoklonalt antistof
DK69590D0 (da) Humane anti-rh(d) monoklonale antistoffer
NO873488L (no) Monoklonale antistoffer.
DK329789D0 (da) Monoklonalt antistof
DK134487A (da) Monoklonalt antistof med affinitet for humant interleukin-2
NO890116L (no) Monoklonale antistoffer.
DK413389A (da) Monoklonale antistoffer
DE69023717D1 (de) Monoklonaler Antikörper.
DE68916088D1 (de) Anti-CPBII-monoklonaler Antikörper.
DK220688D0 (da) Monoklonalt antistof
DE69026453D1 (de) Antirhodopsiner monoklonaler Antikörper and seine Verwendung
DK594189D0 (da) Anti-hcg-antistoffer