NL190662C - alfa-Halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat. - Google Patents

alfa-Halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat.

Info

Publication number
NL190662C
NL190662C NL7807453A NL7807453A NL190662C NL 190662 C NL190662 C NL 190662C NL 7807453 A NL7807453 A NL 7807453A NL 7807453 A NL7807453 A NL 7807453A NL 190662 C NL190662 C NL 190662C
Authority
NL
Netherlands
Prior art keywords
alpha
halo
methyl
amino acid
pharmaceutical composition
Prior art date
Application number
NL7807453A
Other languages
English (en)
Other versions
NL7807453A (nl
NL190662B (nl
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of NL7807453A publication Critical patent/NL7807453A/nl
Publication of NL190662B publication Critical patent/NL190662B/nl
Application granted granted Critical
Publication of NL190662C publication Critical patent/NL190662C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
NL7807453A 1977-07-11 1978-07-11 alfa-Halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat. NL190662C (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81476577A 1977-07-11 1977-07-11
US2875879A 1979-04-10 1979-04-10
US2875779A 1979-04-10 1979-04-10

Publications (3)

Publication Number Publication Date
NL7807453A NL7807453A (nl) 1979-01-15
NL190662B NL190662B (nl) 1994-01-17
NL190662C true NL190662C (nl) 1994-06-16

Family

ID=27363337

Family Applications (2)

Application Number Title Priority Date Filing Date
NL7807453A NL190662C (nl) 1977-07-11 1978-07-11 alfa-Halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat.
NL950027C NL950027I2 (nl) 1977-07-11 1995-11-17 Alfa-halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat die dit bevat.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL950027C NL950027I2 (nl) 1977-07-11 1995-11-17 Alfa-halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat die dit bevat.

Country Status (9)

Country Link
JP (1) JPS5419913A (nl)
AU (1) AU522660B2 (nl)
BE (3) BE868882A (nl)
CA (1) CA1091661A (nl)
CH (1) CH642055A5 (nl)
DE (1) DE2828739A1 (nl)
FR (1) FR2430418A1 (nl)
GB (1) GB2001960B (nl)
NL (2) NL190662C (nl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399151A (en) 1980-06-16 1983-08-16 Merrell Dow Pharmaceuticals Inc. Method of inhibiting the growth of protozoa
ZA813953B (en) * 1980-06-16 1982-06-30 Merrell Dow Pharma Method of inhibiting the growth of protozoa
JPS5791958A (en) * 1980-08-23 1982-06-08 Merrell Toraude & Co Fluorinated pentene diamine derivative
GB2083030B (en) * 1980-08-23 1984-03-07 Merrell Toraude & Co Fluorinated pentene diamine derivatives
US4437873A (en) 1981-03-23 1984-03-20 Merrell Dow Pharmaceuticals Inc. Method of inhibiting algae
US4446151A (en) * 1981-08-19 1984-05-01 Merrell Toraude Et Compagnie Decarboxylase-inhibiting fluorinated pentane diamine derivatives
US4423073A (en) 1981-08-19 1983-12-27 Merrell Toraude Et Compagnie Fluorinated diaminopentene derivatives
US4435425A (en) 1982-04-09 1984-03-06 Merrell Toraude Et Compagnie Fluorinated diaminobutane derivatives
JPS62148462A (ja) * 1985-12-19 1987-07-02 メレルダウフア−マス−テイカルズ インコ−ポレ−テツド 原生動物の生長を抑制する新規な方法
ATE77367T1 (de) * 1988-02-05 1992-07-15 Merrell Dow Pharma 5-substituierte ornithin-derivate.
CA1319123C (en) * 1988-08-31 1993-06-15 Andrew T. Au Method for the production of (-) 2-substituted-ornithines
US6187296B1 (en) 1998-01-23 2001-02-13 The Board Of Regents Of The University Of Oklahoma Lysine decarboxylase inhibitors for the prevention and treatment of periodontal disease
US6103220A (en) * 1998-01-23 2000-08-15 Levine; Martin Lysine decarboxylase inhibitors for the prevention and treatment of periodontal disease
US7015349B2 (en) 2003-03-26 2006-03-21 The Gillette Company Reduction of hair growth
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ187377A (en) * 1977-06-01 1981-05-15 Merck & Co Inc A-amino-a-substituted alkyl-a-fluoromethylacetic acids

Also Published As

Publication number Publication date
BE868882A (fr) 1978-11-03
CH642055A5 (de) 1984-03-30
AU522660B2 (en) 1982-06-17
GB2001960A (en) 1979-02-14
BE881208A (fr) 1980-05-16
JPH0122259B2 (nl) 1989-04-25
NL7807453A (nl) 1979-01-15
FR2430418A1 (fr) 1980-02-01
FR2430418B1 (nl) 1984-07-13
DE2828739A1 (de) 1979-02-01
CA1091661A (en) 1980-12-16
BE881209A (fr) 1980-05-16
JPS5419913A (en) 1979-02-15
AU3732778A (en) 1980-01-03
NL190662B (nl) 1994-01-17
NL950027I1 (nl) 1996-02-01
NL950027I2 (nl) 1997-06-02
GB2001960B (en) 1982-02-24

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
U Licences registered with regard to patents granted
AC1 Application for a supplementary protection certificate

Free format text: 0950027, 951117

TNT Modifications of names of proprietors of patents or applicants of examined patent applications

Owner name: MARION MERRELL ET COMPAGNIE;MARION MERRELL DOW ET

KC1 Grant of a supplementary protection certificate

Free format text: 950027, 19980711, EXPIRES: 20030710

V4 Lapsed because of reaching the maximum lifetime of a patent

Free format text: 980711