NL190268C - METHOD FOR PREPARING A BLOOD CLOTTING PROMOTING PREPARATION BASED ON HUMANE PROTEINS. - Google Patents

METHOD FOR PREPARING A BLOOD CLOTTING PROMOTING PREPARATION BASED ON HUMANE PROTEINS.

Info

Publication number
NL190268C
NL190268C NLAANVRAGE8103329,A NL8103329A NL190268C NL 190268 C NL190268 C NL 190268C NL 8103329 A NL8103329 A NL 8103329A NL 190268 C NL190268 C NL 190268C
Authority
NL
Netherlands
Prior art keywords
proteins
humane
preparing
preparation based
blood clotting
Prior art date
Application number
NLAANVRAGE8103329,A
Other languages
Dutch (nl)
Other versions
NL8103329A (en
NL190268B (en
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of NL8103329A publication Critical patent/NL8103329A/en
Publication of NL190268B publication Critical patent/NL190268B/en
Application granted granted Critical
Publication of NL190268C publication Critical patent/NL190268C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

In a method of producing a blood-coagulation-promoting preparation based on human proteins and having a content of coagulation factors II, VII, IX and X and factor-VIII-inhibitor-bypassing-activity (FEIBA), human plasma is treated with sulphated high-polymer carbohydrates and/or with basic ion exchangers, the protein mixture with generated FEIB-activity is adsorbed on the ion exchanger, and the preparation is gained by elution and concentration.
NLAANVRAGE8103329,A 1980-07-22 1981-07-13 METHOD FOR PREPARING A BLOOD CLOTTING PROMOTING PREPARATION BASED ON HUMANE PROTEINS. NL190268C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT378180 1980-07-22
AT0378180A ATA378180A (en) 1980-07-22 1980-07-22 METHOD FOR PRODUCING A NEW HUMAN PROTEIN-BASED PREPARATION PROCESSING BLOOD

Publications (3)

Publication Number Publication Date
NL8103329A NL8103329A (en) 1982-02-16
NL190268B NL190268B (en) 1993-08-02
NL190268C true NL190268C (en) 1994-01-03

Family

ID=3555339

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE8103329,A NL190268C (en) 1980-07-22 1981-07-13 METHOD FOR PREPARING A BLOOD CLOTTING PROMOTING PREPARATION BASED ON HUMANE PROTEINS.

Country Status (17)

Country Link
US (1) US4395396A (en)
AR (1) AR227194A1 (en)
AT (2) ATA378180A (en)
BE (1) BE889640A (en)
CH (1) CH646061A5 (en)
DE (1) DE3127318A1 (en)
DK (1) DK155500C (en)
ES (1) ES504000A0 (en)
FI (1) FI77048C (en)
FR (1) FR2487199A1 (en)
GB (1) GB2080312B (en)
HU (1) HU188298B (en)
IT (1) IT1142032B (en)
LU (1) LU83499A1 (en)
NL (1) NL190268C (en)
NO (1) NO157245C (en)
SE (1) SE460174B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE36457T1 (en) * 1983-05-02 1988-09-15 Immuno Ag METHOD OF INACTIVATING REPRODUCTIVE pathogens.
AT379510B (en) * 1983-05-20 1986-01-27 Immuno Ag METHOD FOR PRODUCING A FACTOR VIII (AHF) CONTAINING PRAEPARATION
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
AT389815B (en) * 1984-03-09 1990-02-12 Immuno Ag METHOD FOR INACTIVATING VARIABLE FILTERABLE DISEASERS IN BLOOD PRODUCTS
US4710381A (en) * 1984-05-22 1987-12-01 The Blood Center Of Southeastern Wisconsin Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
US5149787A (en) * 1984-05-22 1992-09-22 The Blood Center Research Foundation Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
FR2622108B1 (en) * 1987-10-23 1990-03-02 Lille Transfusion Sanguine PREPARATION OF PROCONVERTINE CONCENTRATES (FACTOR VII), ANTIHEMOPHILIC FACTOR B (FACTOR IX) AND OTHER PLASMA PROTEINS, AND THEIR THERAPEUTIC USE
ES2045167T5 (en) * 1987-10-23 1996-07-01 Centre Regional De Transfusion PREPARATION OF HUMAN FACTOR IX CONCENTRATE OF HIGH PURITY AND OTHER PLASMA PROTEINS.
DE3843126C3 (en) * 1988-12-22 1994-10-06 Octapharma Ag Process for the production of a high-purity thrombin concentrate
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
AT395597B (en) * 1991-01-25 1993-01-25 Immuno Ag REAGENT FOR DETERMINING FACTOR VIII ACTIVITY
RU2142806C1 (en) 1991-03-01 1999-12-20 Сентеон Л.Л.С. Method of purification and storage of, aqueous solution of purified factor ix, composition containing factor ix, and method of treatment
AT398079B (en) * 1991-11-04 1994-09-26 Immuno Ag PREPARATION WITH THROMBINE ACTIVITY AND METHOD FOR THEIR PRODUCTION
IT1262899B (en) * 1992-03-27 1996-07-22 Sclavo Spa PROCESS FOR THE INSULATION OF FACTOR IX, FACTOR X AND FACTOR II HIGHLY PURIFIED FROM THE PROTROMBINIC COMPLEX OR HUMAN PLASMA
FR2711371B1 (en) * 1993-10-18 1995-12-29 Aetsrn Process for the preparation of an inhibitory inter-alpha-trypsin concentrate for therapeutic use and concentrate obtained.
DE4416166C2 (en) * 1994-05-06 1997-11-20 Immuno Ag Stable preparation for the treatment of blood clotting disorders
DE19531637A1 (en) * 1995-08-28 1997-03-06 Immuno Ag Pharmaceutical composition for the treatment of blood coagulation disorders, method for the production thereof and their use
DE59712322D1 (en) * 1996-03-20 2005-06-30 Baxter Ag Pharmaceutical preparation for the treatment of blood clotting disorders
PT973544E (en) 1997-04-08 2001-12-28 Baxter Ag PREPARATION OF IMMUNOTOLERANT PROTROMBIN COMPLEX
AT405608B (en) * 1997-04-08 1999-10-25 Immuno Ag METHOD FOR INACTIVATING PATHOGENS, ESPECIALLY VIRUSES, IN A BIOLOGICAL MATERIAL
AT405485B (en) * 1997-05-28 1999-08-25 Immuno Ag A PHARMACEUTICAL PREPARATION CONTAINING THE VWF PROPEPTIDE
AT407484B (en) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag MEDICINES FOR PROMOTING Wound Healing
AT411997B (en) 1999-09-14 2004-08-26 Baxter Ag FACTOR IX / FACTOR IXA ACTIVATING ANTIBODIES AND ANTIBODY DERIVATIVES
EP1416946B1 (en) 2000-11-07 2017-12-20 CryoLife, Inc. Expandable foam-like biomaterials and methods
EP1523327A1 (en) * 2002-07-23 2005-04-20 Bio-Products & Bio-Engineering Aktiengesellschaft Pharmaceutical active ingredient preparations and medicaments that contain thrombin or have a thrombin-generating capacity
EP1528930B1 (en) * 2002-07-23 2009-04-15 Bio & Bio Licensing SA Pharmaceutically active substance preparations and drugs that are capable of generating thrombin and/or that contain thrombin
US7297336B2 (en) 2003-09-12 2007-11-20 Baxter International Inc. Factor IXa specific antibodies displaying factor VIIIa like activity
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
RU2648517C1 (en) * 2017-06-23 2018-03-26 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) Method for obtaining a liophilized preparation of an activated protrombin complex having viii-shunting activity factor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492108A1 (en) 1964-05-04 1969-10-02 Rohm & Haas Procedure for removing viruses from blood during collection or transfer
DE2262520B2 (en) * 1972-12-20 1979-10-11 Cutter Laboratories Inc., Berkeley, Calif. (V.St.A.) Process for the production of a lyophilized, storable concentrate from human plasma
US4170590A (en) * 1974-12-14 1979-10-09 Biotest-Serum-Institut Gmbh Ion exchanger treatment of citrate-stabilized plasma
JPS52125609A (en) 1976-04-09 1977-10-21 Green Cross Corp:The Purification of agglutination factor viii
AT350726B (en) * 1976-08-30 1979-06-11 Immuno Ag PROCESS FOR THE PRODUCTION OF A BLOOD CLOTIFYING PREPARATION FROM HUMAN BLOOD PLASMA
US4081432A (en) 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers
US4286056A (en) * 1980-01-28 1981-08-25 Baxter Travenol Laboratories, Inc. Method for making therapeutic enzyme compositions
JPH0686385B2 (en) * 1980-01-28 1994-11-02 バクスタ−、インタ−ナショナル、インコ−ポレイテッド Active prothrombin complex composition and method for producing the same
US4287180A (en) * 1980-01-28 1981-09-01 Baxter Travenol Laboratories, Inc. Method for treating blood clotting factor inhibitors
US4364861A (en) * 1980-05-27 1982-12-21 Cutter Laboratories, Inc. Blood-coagulation-promoting products and methods of preparing them

Also Published As

Publication number Publication date
DE3127318A1 (en) 1982-04-15
DE3127318C2 (en) 1988-07-28
BE889640A (en) 1981-11-03
NL8103329A (en) 1982-02-16
DK155500B (en) 1989-04-17
FI77048B (en) 1988-09-30
FR2487199A1 (en) 1982-01-29
ES8203610A1 (en) 1982-04-16
IT8123070A0 (en) 1981-07-22
FI812295L (en) 1982-01-23
GB2080312B (en) 1983-12-21
ES504000A0 (en) 1982-04-16
SE8103759L (en) 1982-01-23
HU188298B (en) 1986-03-28
AR227194A1 (en) 1982-09-30
GB2080312A (en) 1982-02-03
NL190268B (en) 1993-08-02
DK318581A (en) 1982-01-23
CH646061A5 (en) 1984-11-15
NO812500L (en) 1982-01-25
DK155500C (en) 1989-08-07
FI77048C (en) 1989-01-10
FR2487199B1 (en) 1984-11-16
US4395396A (en) 1983-07-26
AT368883B (en) 1982-11-25
NO157245B (en) 1987-11-09
IT1142032B (en) 1986-10-08
SE460174B (en) 1989-09-18
ATA378180A (en) 1982-04-15
LU83499A1 (en) 1981-10-29
NO157245C (en) 1988-02-24

Similar Documents

Publication Publication Date Title
NL190268C (en) METHOD FOR PREPARING A BLOOD CLOTTING PROMOTING PREPARATION BASED ON HUMANE PROTEINS.
DE3379644D1 (en) Adsorbent and process for preparing the same
ATE287210T1 (en) TREATMENT OF RED BLOOD CELL SOLUTIONS WITH ANTIVIRAL ACTIVE INGREDIENTS
EP0180452A3 (en) Three-phase irradiation blood-treatment process
AU7770581A (en) Hepatitis-safe blood-clotting factors
AT362534B (en) METHOD FOR PRODUCING GLYCOSYLATED HAEMOGLOBIN IN BLOOD AND REAGENTS FOR CARRYING OUT THE METHOD
SE8902565L (en) PREPARED FOR PREPARATION OF A PRIOR IMPLANT DEDICATED BODY
ATE17262T1 (en) PROCEDURE FOR THE QUANTITATIVE DETERMINATION OF COAGAGING FACTOR XII IN HUMAN PLASMA.
ATE12318T1 (en) METHOD AND REAGENT FOR THE DETERMINATION OF GLYCOSILATED HAEMOGLOBIN.
DK292090D0 (en) PROCEDURE FOR PREPARING AN ANTHITHROMBINE III CONCENTRATE
PT79117B (en) METHOD FOR PASTEURIZING HUMAN PLASMA
ATE76751T1 (en) PROCEDURE FOR ISOLATION OF BLOOD COAGULATION FACTOR IX.
ATE105086T1 (en) DIAGNOSTIC MEANS AND METHOD FOR DETERMINING APOLIPOPROTEIN B.
HU904183D0 (en) Process and reagent for determination of haemoglobine
EP0317085A3 (en) Processed red blood cells and process for producing the same
ATE55059T1 (en) PROCEDURE FOR INACTIVATING INTOLERABLE SUBSTANCES.
ATE2049T1 (en) MEANS OF THERAPY OF IMMUNOCOMPLEX DISEASES.
DK56386A (en) REAGENTS FOR HOMAGGLUNITATION TO DETERMINE ANTIBODIES AGAINST BACTERIAL TOXINES, PROCEDURE FOR PREPARING THE REAGENT, AND ITS USE
ATE124706T1 (en) METHOD FOR ISOLATION OF BASAL MEMBRANE PROTEINS FROM HUMAN AND ANIMAL TISSUES.
GB906860A (en) Improvements relating to blood coagulation test reagents
JPS5726625A (en) Sustained release type composite material entrapping medical enzyme and its preparation
JPS5543123A (en) Preparation of highly active heparin
ATE80306T1 (en) MEANS FOR IMPROVING ABSORPTION OF PROTEINS.
ES2137878A1 (en) Procedure for obtaining a virus attenuated human plasma for therapeutic use.
RU94009653A (en) Method for correcting metabolic processes in cell

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
AK Correction of former applications already laid open

Free format text: SHOULD BE DELETED IN PAT.BUL.11 OF 830601,PAGE 1022

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: IMMUNO AKTIENGESELLSCHAFT

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 20010713