NL188544B - Reagens voor immunochemische analysemethoden, uitgevoerd in aanwezigheid van een waterige vloeistof. - Google Patents
Reagens voor immunochemische analysemethoden, uitgevoerd in aanwezigheid van een waterige vloeistof.Info
- Publication number
- NL188544B NL188544B NLAANVRAGE7802451,A NL7802451A NL188544B NL 188544 B NL188544 B NL 188544B NL 7802451 A NL7802451 A NL 7802451A NL 188544 B NL188544 B NL 188544B
- Authority
- NL
- Netherlands
- Prior art keywords
- reagent
- carried out
- aqueous liquid
- analysis methods
- methods carried
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 230000000984 immunochemical effect Effects 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7702464A SE427505B (sv) | 1977-03-04 | 1977-03-04 | Reagens till anvendning vid immunkemiska bestemningsmetoder |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7802451A NL7802451A (nl) | 1978-09-06 |
NL188544B true NL188544B (nl) | 1992-02-17 |
NL188544C NL188544C (nl) | 1993-09-16 |
Family
ID=20330625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NLAANVRAGE7802451,A NL188544C (nl) | 1977-03-04 | 1978-03-06 | Reagens voor immunochemische analysemethoden, uitgevoerd in aanwezigheid van een waterige vloeistof. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4232119A (nl) |
JP (1) | JPS53130423A (nl) |
DE (1) | DE2808476C2 (nl) |
FR (1) | FR2382695A1 (nl) |
GB (1) | GB1597754A (nl) |
NL (1) | NL188544C (nl) |
SE (1) | SE427505B (nl) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2432713A1 (fr) * | 1978-08-02 | 1980-02-29 | Inst Nat Sante Rech Med | Application de la d5,3-ceto steroide isomerase dans les dosages immunoenzymatiques |
JPS55136261A (en) * | 1979-04-12 | 1980-10-23 | Toyo Jozo Co Ltd | Novel compound and kit comprising it |
FR2470773B1 (nl) * | 1979-11-28 | 1983-01-28 | Pasteur Institut | |
US4318981A (en) * | 1980-04-24 | 1982-03-09 | Miles Laboratories, Inc. | Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label |
SE8003732L (sv) * | 1980-05-19 | 1981-11-20 | Pharmacia Diagnostics Ab | Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner |
US4486540A (en) * | 1980-07-18 | 1984-12-04 | Science Research Center, Inc. | Identification of reagins in the blood serum of allergen sensitized vertebrates |
US4696907A (en) * | 1980-07-18 | 1987-09-29 | Science Research Center, Inc. | Identification of reagins in the blood serum of allergen sensitized vertebrates |
SE8102193L (sv) * | 1981-04-06 | 1982-10-07 | Pharmacia Ab | Terapeutiskt aktiv organisk forening och dess anvendning |
SE8102194L (sv) * | 1981-04-06 | 1982-10-07 | Pharmacia Ab | Terapeutiskt aktiv organisk forening och farmaceutisk beredning innehallande denna |
US4481298A (en) * | 1981-04-13 | 1984-11-06 | Amf Incorporated | Pre-precipitated double antibody immunoassay method |
NL8102178A (nl) * | 1981-05-02 | 1982-12-01 | Stichting Centraal Lab | Werkwijze voor het aantonen van tegen bepaalde antigenen gerichte antistoffen, alsmede inrichting en reagentia voor het uitvoeren van deze werkwijze. |
FR2523445A1 (fr) * | 1982-03-17 | 1983-09-23 | Sanofi Sa | Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues |
US4614712A (en) * | 1983-02-25 | 1986-09-30 | The Upjohn Company | Immunoassays with luciferase labeled ligands or receptors |
SE8302758L (sv) * | 1983-05-17 | 1984-11-18 | Pharmacia Ab | Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening |
US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
GB8334499D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Derivatives |
GB8400653D0 (en) * | 1984-01-11 | 1984-02-15 | Beecham Group Plc | Conjugates |
US4665022A (en) * | 1984-02-17 | 1987-05-12 | The Regents Of The University Of California | Bioluminescent assay reagent and method |
WO1986005098A1 (en) * | 1985-03-04 | 1986-09-12 | Dana-Farber Cancer Institute, Inc. | Immunotoxin and method of making |
US4888415A (en) * | 1985-03-04 | 1989-12-19 | Dana-Farber Cancer Institute, Inc. | Gelonin immunotoxin |
US4863875A (en) * | 1985-08-26 | 1989-09-05 | Gia Research Company, L.P. | Dye labelled antibodies as reagents for use in immunoassay systems |
FR2586813B1 (fr) * | 1985-08-30 | 1989-05-12 | Inst Nat Sante Rech Med | Supports proteiques modifies aptes a immobiliser de facon reversible des anticorps ou des substances immunologiquement actives, et leurs applications au dosage et a la purification d'antigenes ou similaires. |
US4780421A (en) * | 1986-04-03 | 1988-10-25 | Sclavo Inc. | Cleavable labels for use in binding assays |
US4959306A (en) * | 1986-11-28 | 1990-09-25 | Sclavo, Inc. | Labeling design for a binding assay reagent |
US4975532A (en) * | 1986-11-28 | 1990-12-04 | Sclavo, Inc. | Method to derivatize dextran |
WO1988007200A1 (en) * | 1987-03-19 | 1988-09-22 | Perry, Robert, Edward | Monoclonal antibody conjugation |
US5171563A (en) * | 1988-09-30 | 1992-12-15 | Neorx Corporation | Cleavable linkers for the reduction of non-target organ retention of immunoconjugates |
GB8927365D0 (en) * | 1989-12-04 | 1990-01-31 | Ici Plc | Reagent |
US5324650A (en) * | 1990-03-20 | 1994-06-28 | E. I. Du Pont De Nemours And Company | Situ process for production of conjugates |
US6274325B1 (en) * | 1990-06-25 | 2001-08-14 | Boehringer Mannheim Gmbh | Method for carrying out a homogeneous-immunoassay based on agglutination |
US5191066A (en) * | 1990-12-07 | 1993-03-02 | Abbott Laboratories | Site-specific conjugation of immunoglobulins and detectable labels |
US5331109A (en) * | 1992-04-06 | 1994-07-19 | Biosite Diagnostics Incorporated | Phencyclidine derivatives and protein and polypeptide phencyclidine derivative conjugates and labels |
US5470997A (en) * | 1992-04-06 | 1995-11-28 | Biosite Diagnostics Incorporated | Amphetamine derivatives and protein and polypeptide amphetamine derivative conjugates and labels |
DE69325096T2 (de) * | 1992-04-06 | 1999-09-30 | Biosite Diagnostics Inc., San Diego | Morphinderivate sowie deren konjugate und labels mit proteinen und polypeptiden |
US6037455A (en) * | 1992-11-09 | 2000-03-14 | Biosite Diagnostics Incorporated | Propoxyphene derivatives and protein and polypeptide propoxyphene derivative conjugates and labels |
US5536820A (en) * | 1993-02-26 | 1996-07-16 | E. I. Du Pont De Nemours And Company | Avidin-binding azo reagents |
US5736624A (en) * | 1994-12-02 | 1998-04-07 | Abbott Laboratories | Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
AU2002319613A1 (en) * | 2001-07-19 | 2003-03-03 | Signet Laboratories, Inc. | Human tissue specific drug screening procedure |
AU2003256803B2 (en) * | 2003-01-24 | 2009-09-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target activated microtransfer |
US7695752B2 (en) * | 2003-01-24 | 2010-04-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target activated microtransfer |
US20040180054A1 (en) * | 2003-03-13 | 2004-09-16 | Hanmi Pharm. Co., Ltd. | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
US20050176108A1 (en) * | 2003-03-13 | 2005-08-11 | Young-Min Kim | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
CA2606018A1 (en) * | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc. | Nanoparticle conjugates |
EP1877101B1 (en) | 2005-04-28 | 2016-11-16 | Ventana Medical Systems, Inc. | Enzymes conjugated to antibodies via a peg heterobifuctional linker |
US7957466B2 (en) * | 2005-09-16 | 2011-06-07 | Sony Corporation | Adaptive area of influence filter for moving object boundaries |
EP1951316B1 (en) * | 2005-11-23 | 2015-08-19 | Ventana Medical Systems, Inc. | Molecular conjugate |
US8460878B2 (en) | 2006-02-21 | 2013-06-11 | The Trustees Of Tufts College | Methods and arrays for detecting cells and cellular components in small defined volumes |
US11237171B2 (en) | 2006-02-21 | 2022-02-01 | Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of target analyte concentration in solution |
JP5503540B2 (ja) | 2007-08-30 | 2014-05-28 | トラスティーズ・オブ・タフツ・カレッジ | 溶液中の分析物濃度を決定する方法 |
US20100075439A1 (en) * | 2008-09-23 | 2010-03-25 | Quanterix Corporation | Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification |
US20100075862A1 (en) * | 2008-09-23 | 2010-03-25 | Quanterix Corporation | High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample |
US8222047B2 (en) | 2008-09-23 | 2012-07-17 | Quanterix Corporation | Ultra-sensitive detection of molecules on single molecule arrays |
US9910040B2 (en) * | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
EP2504702A4 (en) * | 2009-11-24 | 2014-12-17 | Argos Inc | DEVICES FOR DETECTING ANALYTES |
US9733242B2 (en) | 2012-10-07 | 2017-08-15 | Sevident, Inc. | Devices for capturing analyte |
ES2544635T3 (es) | 2010-03-01 | 2015-09-02 | Quanterix Corporation | Métodos para extender el rango dinámico en ensayos para la detección de moléculas o partículas |
US8415171B2 (en) | 2010-03-01 | 2013-04-09 | Quanterix Corporation | Methods and systems for extending dynamic range in assays for the detection of molecules or particles |
US9678068B2 (en) | 2010-03-01 | 2017-06-13 | Quanterix Corporation | Ultra-sensitive detection of molecules using dual detection methods |
US8236574B2 (en) | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
EP2619588B1 (en) * | 2010-09-23 | 2019-08-07 | Biocept, Inc. | Methods and reagents for signal amplification |
US9952237B2 (en) | 2011-01-28 | 2018-04-24 | Quanterix Corporation | Systems, devices, and methods for ultra-sensitive detection of molecules or particles |
WO2012142301A2 (en) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury |
US9932626B2 (en) | 2013-01-15 | 2018-04-03 | Quanterix Corporation | Detection of DNA or RNA using single molecule arrays and other techniques |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4004979A (en) * | 1968-03-29 | 1977-01-25 | Agence Nationale De Valorisation De La Recherche (Anvar) | Preparation of active proteins cross-linked to inactive proteins |
US3652761A (en) * | 1969-09-04 | 1972-03-28 | Corning Glass Works | Immunochemical composites and antigen or antibody purification therewith |
SE420733B (sv) * | 1974-05-30 | 1981-10-26 | Exploaterings Ab Tbf | Gelprodukt, innehallande tiosulfatgrupper samt sett for framstellning derav |
US4002532A (en) * | 1974-10-21 | 1977-01-11 | Weltman Joel K | Enzyme conjugates |
-
1977
- 1977-03-04 SE SE7702464A patent/SE427505B/xx not_active IP Right Cessation
-
1978
- 1978-02-28 DE DE2808476A patent/DE2808476C2/de not_active Expired
- 1978-03-02 US US05/882,545 patent/US4232119A/en not_active Expired - Lifetime
- 1978-03-03 FR FR7806163A patent/FR2382695A1/fr active Granted
- 1978-03-03 GB GB8451/78A patent/GB1597754A/en not_active Expired
- 1978-03-04 JP JP2406478A patent/JPS53130423A/ja active Granted
- 1978-03-06 NL NLAANVRAGE7802451,A patent/NL188544C/nl not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE2808476A1 (de) | 1978-09-07 |
FR2382695B1 (nl) | 1984-07-13 |
JPS6145775B2 (nl) | 1986-10-09 |
SE7702464L (sv) | 1978-09-05 |
SE427505B (sv) | 1983-04-11 |
JPS53130423A (en) | 1978-11-14 |
DE2808476C2 (de) | 1986-11-06 |
NL7802451A (nl) | 1978-09-06 |
NL188544C (nl) | 1993-09-16 |
FR2382695A1 (fr) | 1978-09-29 |
GB1597754A (en) | 1981-09-09 |
US4232119A (en) | 1980-11-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
R1B | Notice of opposition during period of laying open | ||
NP1 | Patent granted (not automatically) | ||
V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19971001 |