NL187629C - Werkwijze voor de bereiding van een farmacologisch preparaat alsmede werkwijze voor de bereiding van daarbij toe te passen fenylmethylsulfinylverbindingen. - Google Patents

Werkwijze voor de bereiding van een farmacologisch preparaat alsmede werkwijze voor de bereiding van daarbij toe te passen fenylmethylsulfinylverbindingen.

Info

Publication number: NL187629C
Authority: NL; Netherlands
Prior art keywords: preparation; compounds used; pharmacological; used therefor; phenyl methyl
Prior art date: 1975-10-02

Application number

NLAANVRAGE7610929,A

Other languages

English (en)

Other versions

NL187629B (nl

NL7610929A (nl

Original Assignee

Lafon Labor

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-02

Filing date

1976-10-01

Publication date

1991-12-02

1976-10-01 Application filed by Lafon Labor filed Critical Lafon Labor

1977-04-05 Publication of NL7610929A publication Critical patent/NL7610929A/nl

1991-07-01 Publication of NL187629B publication Critical patent/NL187629B/nl

1991-12-02 Application granted granted Critical

1991-12-02 Publication of NL187629C publication Critical patent/NL187629C/nl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Electronic Switches (AREA)

NLAANVRAGE7610929,A 1975-10-02 1976-10-01 Werkwijze voor de bereiding van een farmacologisch preparaat alsmede werkwijze voor de bereiding van daarbij toe te passen fenylmethylsulfinylverbindingen. NL187629C (nl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB40419/75A GB1520812A (en)	1975-10-02	1975-10-02	Benzhydrylsulphinyl derivatives

Publications (3)

Publication Number	Publication Date
NL7610929A NL7610929A (nl)	1977-04-05
NL187629B NL187629B (nl)	1991-07-01
NL187629C true NL187629C (nl)	1991-12-02

Family

ID=10414819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7610929,A NL187629C (nl)	1975-10-02	1976-10-01	Werkwijze voor de bereiding van een farmacologisch preparaat alsmede werkwijze voor de bereiding van daarbij toe te passen fenylmethylsulfinylverbindingen.

Country Status (29)

Country	Link
US (1)	US4066686A (nl)
JP (1)	JPS6045186B2 (nl)
AT (1)	AT347426B (nl)
AU (1)	AU511619B2 (nl)
BE (1)	BE846880A (nl)
CH (1)	CH614934A5 (nl)
CS (1)	CS200195B2 (nl)
DE (1)	DE2642511C2 (nl)
DK (1)	DK151009C (nl)
ES (1)	ES452063A1 (nl)
FI (1)	FI63220C (nl)
FR (1)	FR2326181A1 (nl)
GB (1)	GB1520812A (nl)
GE (1)	GEP19960242B (nl)
HU (1)	HU175109B (nl)
IE (1)	IE43553B1 (nl)
IL (1)	IL50599A (nl)
LU (1)	LU75909A1 (nl)
NL (1)	NL187629C (nl)
NO (1)	NO143219C (nl)
NZ (1)	NZ182207A (nl)
OA (1)	OA05444A (nl)
PH (1)	PH12533A (nl)
PL (1)	PL105506B1 (nl)
PT (1)	PT65648B (nl)
SE (1)	SE431088B (nl)
SU (1)	SU651693A3 (nl)
YU (1)	YU40464B (nl)
ZA (1)	ZA765830B (nl)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1106403A (en) *	1977-04-29	1981-08-04	Victor Lafon	Process for preparing (3,4-dichlorophenyl-sulphinyl)- acetamidoxime and its addition salts
FR2528041A1 (fr) *	1982-06-04	1983-12-09	Lafon Labor	Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique
FR2528040A1 (fr) *	1982-06-04	1983-12-09	Lafon Labor	Benzhydrylsulfinylethylamines, procede de preparation et utilisation en therapeutique
GB8320943D0 (en) *	1983-08-03	1983-09-07	Lilly Industries Ltd	Organic compounds
FR2561646B1 (fr) *	1984-03-23	1987-10-09	Lafon Labor	Derives d'acide (a-(alkylaminomethyl)-benzyl)-thioacetique, procede de preparation et utilisation en therapeutique
FR2569186B1 (fr) *	1984-08-20	1986-09-05	Lafon Labor	Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique
DE3604050A1 (de) *	1986-02-08	1987-08-13	Boehringer Mannheim Gmbh	Thioether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
FR2606015B1 (fr) *	1986-08-13	1989-05-19	Lafon Labor	Derives du benzhydrylthiomethane, leurs procedes de preparation et leurs applications en therapeutique
JPH02162176A (ja) *	1988-12-14	1990-06-21	Sanyo Electric Co Ltd	ライトの取付装置
FR2663225B1 (fr) *	1990-06-14	1994-11-04	Lafon Labor	Nouvelle utilisation du modafinil.
FR2708201B1 (fr) *	1993-06-30	1995-10-20	Lafon Labor	Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5571825A (en) *	1995-03-31	1996-11-05	Warner-Lambert Company	Method of selectively inhibiting prostaglandin G/H synthase-2
US6172057B1 (en)	1997-02-27	2001-01-09	American Cyanamid Company	N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
YU40999A (sh) *	1997-02-27	2002-06-19	American Cyanamid Company	N-hidroksi-2-(alkil,aril ili heteroaril sulfanil,sulfinil ili sulfonil)-3-supstituisani alkil,aril ili heteroarilamidi, kao inhibitori za matrične metaloproteinaze
US6670358B2 (en) *	2000-05-16	2003-12-30	Cephalon, Inc.	Substituted thioacetamides
US6492396B2 (en) *	2000-05-16	2002-12-10	Cephalon, Inc.	Substituted thioacetamides
US6875893B2 (en) *	2002-05-23	2005-04-05	Cephalon, Inc.	Preparations of a sulfinyl acetamide
US6992219B2 (en) *	2002-08-09	2006-01-31	Cephalon France	Modafinil polymorphic forms
EP1437345A1 (en) *	2003-01-13	2004-07-14	Organisation de Synthese Mondiale Orsymonde	Novel method for preparing methyl 2-diphenylmethylsulfinylacetate
CA2514900A1 (en)	2003-01-31	2004-09-10	Alembic Limited	Process for the preparation of 2-[(diphenylmethyl) thio] acetamide
US7244865B2 (en) *	2003-02-24	2007-07-17	Mallinckrodt Inc.	Process for preparing benzhydrylthioacetamide
ITMI20031298A1 (it) *	2003-06-26	2004-12-27	Erregierre Spa	Processo di preparazione di modafinil forma polimorfa(i).
WO2005046854A2 (en) *	2003-09-12	2005-05-26	Sun Pharmaceutical Industries Limited	A process for the preparation of diphenylmethylsulfinyl derivatives
EP1586560A1 (en) *	2004-04-13	2005-10-19	Cephalon, Inc.	Thio-substituted arylmethanesulfinyl derivatives
US7449481B2 (en) *	2004-04-13	2008-11-11	Cephalon, Inc.	Thio-substituted biaryl-methanesulfinyl derivatives
US7314875B2 (en) *	2004-04-13	2008-01-01	Cephalon, Inc.	Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US7119214B2 (en) *	2004-04-13	2006-10-10	Cephalon France	Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US7297817B2 (en) *	2004-04-13	2007-11-20	Cephalon France	Thio-substituted arylmethanesulfinyl derivatives
MX2009000391A (es) *	2006-07-12	2009-06-30	Elan Pharma Int Ltd	Formulación de modafinilo en forma de nano-partículas.
US20100010092A1 (en) *	2006-12-19	2010-01-14	Arless Ltd.	Use of modafinil to treat restless leg syndrome
USD681056S1 (en) *	2012-09-09	2013-04-30	Apple Inc.	Electronic device
WO2014138518A2 (en)	2013-03-08	2014-09-12	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
CN104610108B (zh) *	2015-01-27	2016-03-30	潍坊医学院	一种中枢神经***药物阿屈非尼中间体化合物的合成方法
US11365195B2 (en)	2017-11-13	2022-06-21	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Atypical inhibitors of monoamine transporters; method of making; and use thereof
KR102126389B1 (ko)	2018-09-14	2020-06-25	셀라이온바이오메드 주식회사	벤즈히드릴티오 아세트아미드 화합물을 유효성분으로 포함하는 간 질환의 예방 또는 치료용 조성물
KR102277739B1 (ko)	2019-12-11	2021-07-15	셀라이온바이오메드 주식회사	벤즈히드릴 티오 아세트아미드 화합물을 유효성분으로 포함하는 섬유화 질환의 치료용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2394597A (en) *	1942-07-09	1946-02-12	Eastman Kodak Co	Preparation of organic dhsocyanates
NL6406688A (nl) *	1964-06-05	1965-12-06

1975
- 1975-10-02 GB GB40419/75A patent/GB1520812A/en not_active Expired
1976
- 1976-09-13 CH CH1159776A patent/CH614934A5/xx not_active IP Right Cessation
- 1976-09-22 DE DE2642511A patent/DE2642511C2/de not_active Expired
- 1976-09-24 PH PH18944A patent/PH12533A/en unknown
- 1976-09-27 PT PT65648A patent/PT65648B/pt unknown
- 1976-09-27 IE IE2135/76A patent/IE43553B1/en not_active IP Right Cessation
- 1976-09-28 FR FR7629137A patent/FR2326181A1/fr active Granted
- 1976-09-28 ZA ZA765830A patent/ZA765830B/xx unknown
- 1976-09-29 AT AT720876A patent/AT347426B/de not_active IP Right Cessation
- 1976-09-29 DK DK437576A patent/DK151009C/da not_active IP Right Cessation
- 1976-09-29 OA OA55945A patent/OA05444A/xx unknown
- 1976-09-30 LU LU75909A patent/LU75909A1/xx unknown
- 1976-09-30 US US05/728,054 patent/US4066686A/en not_active Expired - Lifetime
- 1976-10-01 YU YU2414/76A patent/YU40464B/xx unknown
- 1976-10-01 ES ES452063A patent/ES452063A1/es not_active Expired
- 1976-10-01 NO NO763372A patent/NO143219C/no unknown
- 1976-10-01 NL NLAANVRAGE7610929,A patent/NL187629C/nl not_active IP Right Cessation
- 1976-10-01 CS CS766356A patent/CS200195B2/cs unknown
- 1976-10-01 SE SE7610940A patent/SE431088B/xx not_active IP Right Cessation
- 1976-10-01 NZ NZ182207A patent/NZ182207A/xx unknown
- 1976-10-01 IL IL50599A patent/IL50599A/xx unknown
- 1976-10-01 SU SU762404903A patent/SU651693A3/ru active
- 1976-10-01 FI FI762810A patent/FI63220C/fi not_active IP Right Cessation
- 1976-10-01 HU HU76LA894A patent/HU175109B/hu unknown
- 1976-10-01 BE BE171191A patent/BE846880A/xx not_active IP Right Cessation
- 1976-10-01 PL PL1976192811A patent/PL105506B1/pl unknown
- 1976-10-02 JP JP51118908A patent/JPS6045186B2/ja not_active Expired
1978
- 1978-09-29 AU AU18188/76A patent/AU511619B2/en not_active Expired
1992
- 1992-12-09 GE GEAP1992402A patent/GEP19960242B/en unknown

Also Published As

Publication number	Publication date
FR2326181A1 (fr)	1977-04-29
NZ182207A (en)	1978-03-06
NL187629B (nl)	1991-07-01
PT65648A (pt)	1976-10-01
FI63220B (fi)	1983-01-31
GEP19960242B (en)	1996-06-01
CH614934A5 (nl)	1979-12-28
ATA720876A (de)	1978-05-15
JPS5246058A (en)	1977-04-12
SE431088B (sv)	1984-01-16
AU511619B2 (en)	1980-08-28
NL7610929A (nl)	1977-04-05
DK151009B (da)	1987-10-12
FI762810A (nl)	1977-04-03
HU175109B (hu)	1980-05-28
BE846880A (fr)	1977-04-01
IL50599A (en)	1980-09-16
ZA765830B (en)	1977-09-28
DE2642511C2 (de)	1986-07-31
CS200195B2 (cs)	1980-08-29
NO143219C (no)	1981-01-07
YU241476A (en)	1982-02-28
AU1818876A (en)	1978-04-06
PT65648B (fr)	1978-04-07
ES452063A1 (es)	1977-10-01
LU75909A1 (nl)	1977-05-11
NO763372L (nl)	1977-04-05
IE43553B1 (en)	1981-03-25
YU40464B (en)	1986-02-28
IL50599A0 (en)	1976-12-31
SU651693A3 (ru)	1979-03-05
US4066686A (en)	1978-01-03
GB1520812A (en)	1978-08-09
DK151009C (da)	1988-02-29
AT347426B (de)	1978-12-27
PL105506B1 (pl)	1979-10-31
OA05444A (fr)	1981-03-31
FR2326181B1 (nl)	1980-08-08
DK437576A (da)	1977-04-03
IE43553L (en)	1977-04-02
FI63220C (fi)	1983-05-10
DE2642511A1 (de)	1977-04-14
JPS6045186B2 (ja)	1985-10-08
NO143219B (no)	1980-09-22
PH12533A (en)	1979-05-17
SE7610940L (sv)	1977-04-03

Legal Events

Date	Code	Title	Description
1983-10-03	BA	A request for search or an international-type search has been filed
1984-01-02	BB	A search report has been drawn up
1984-03-01	BC	A request for examination has been filed
1985-01-01	A85	Still pending on 85-01-01
1996-12-02	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 961001

Publication	Publication Date	Title
NL187629C (nl)	1991-12-02	Werkwijze voor de bereiding van een farmacologisch preparaat alsmede werkwijze voor de bereiding van daarbij toe te passen fenylmethylsulfinylverbindingen.
NL7608368A (nl)	1977-02-01	Werkwijze voor de bereiding van een bekledings- samenstelling.
NL187064C (nl)	1991-05-16	Werkwijze voor de bereiding van hydroxybenzaldehyden.
NL7709076A (nl)	1978-05-30	Werkwijze voor de bereiding van een vlam-vertra- gende samenstelling.
NL172962B (nl)	1983-06-16	Werkwijze voor de bereiding van polyesteramiden.
NL182476C (nl)	1988-03-16	Werkwijze voor de bereiding van een 4-halogeen-beta-pyron.
NL7601114A (nl)	1976-08-09	Werkwijze voor de bereiding van een farmaceutisch preparaat.
NL7708162A (nl)	1978-01-31	Werkwijze voor de bereiding van een farmaceu- tisch preparaat.
NL7712996A (nl)	1978-05-30	Werkwijze voor de bereiding van een farmaceu- tisch preparaat.
NL184952C (nl)	1989-12-18	Werkwijze voor de bereiding van cyclohexanonoxim.
NL7500820A (nl)	1976-07-27	Werkwijze voor het bereiden van een versnapering.
NL7614190A (nl)	1977-07-07	Werkwijze voor de bereiding van een farmaceutisch preparaat.
NL7601423A (nl)	1976-08-17	Werkwijze voor de bereiding van een farmaceu- tisch preparaat.
NL7601001A (nl)	1976-08-06	Werkwijze voor de bereiding van alkylchloor- aromatische verbindingen.
NL7603671A (nl)	1976-11-25	Werkwijze voor de bereiding van een deodorans en een dergelijk deodorans.
NL7604926A (nl)	1976-11-16	Werkwijze voor de bereiding van een fungicide.
NL188353C (nl)	1992-06-01	Werkwijze voor de bereiding van een fosfoleen-1-chalcogenide.
NL7700424A (nl)	1977-08-08	Werkwijze voor de bereiding van een farmaceu- tisch preparaat.
NL7613527A (nl)	1977-06-07	Werkwijze voor de bereiding van n-methylureum- verbindingen.
NL7607581A (nl)	1977-01-11	Werkwijze voor de bereiding van polyenen.
NL181575C (nl)	1987-09-16	Werkwijze voor de bereiding van o-derivaten van p-isopropenylfenol.
NL7713691A (nl)	1978-06-26	Een loogvrije werkwijze voor de bereiding van monochloordiamino-s-triazinen.
NL7611958A (nl)	1977-05-03	Werkwijze voor de bereiding van een bindmiddel voor waterrijke moffellakken.
NL7611998A (nl)	1977-05-03	Werkwijze voor de bereiding van een fungicide- preparaat.
NL7609066A (nl)	1977-02-22	Werkwijze voor de bereiding van een bactericide preparaat.