NL151693B - PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH A BRONCHOSPASMOLYTIC ACTION CONTAINING A DERIVATIVE OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL AND OBTAINED UNDER APPLICATION OF THIS METHOD OF THE BRONCHOSPASMOLYTIC METHOD OF THE PREPARED METHOD A MEDICINAL 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL DERIVATIVE, USED AS AN ACTIVE INGREDIENT IN SUCH MEDICINAL PRODUCT. - Google Patents

PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH A BRONCHOSPASMOLYTIC ACTION CONTAINING A DERIVATIVE OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL AND OBTAINED UNDER APPLICATION OF THIS METHOD OF THE BRONCHOSPASMOLYTIC METHOD OF THE PREPARED METHOD A MEDICINAL 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL DERIVATIVE, USED AS AN ACTIVE INGREDIENT IN SUCH MEDICINAL PRODUCT.

Info

Publication number: NL151693B
Authority: NL; Netherlands
Prior art keywords: dihydroxyphenyl; amino; derivative; ethanol; bronchospasmolytic
Prior art date: 1966-10-19

Application number

NL676714191A

Other languages

Dutch (nl)

Other versions

NL6714191A (en

Original Assignee

Draco Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-10-19

Filing date

1967-10-19

Publication date

1976-12-15

1967-10-19 Application filed by Draco Ab filed Critical Draco Ab

1968-04-22 Publication of NL6714191A publication Critical patent/NL6714191A/xx

1976-12-15 Publication of NL151693B publication Critical patent/NL151693B/en

Links

238000000034 method Methods 0.000 title 3
VZVBXISLBQEWKU-UHFFFAOYSA-N 5-(2-amino-1-hydroxyethyl)benzene-1,3-diol Chemical class NCC(O)C1=CC(O)=CC(O)=C1 VZVBXISLBQEWKU-UHFFFAOYSA-N 0.000 title 2
230000000572 bronchospasmolytic effect Effects 0.000 title 2
229940126601 medicinal product Drugs 0.000 title 2
239000004480 active ingredient Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NL676714191A 1966-10-19 1967-10-19 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH A BRONCHOSPASMOLYTIC ACTION CONTAINING A DERIVATIVE OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL AND OBTAINED UNDER APPLICATION OF THIS METHOD OF THE BRONCHOSPASMOLYTIC METHOD OF THE PREPARED METHOD A MEDICINAL 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL DERIVATIVE, USED AS AN ACTIVE INGREDIENT IN SUCH MEDICINAL PRODUCT. NL151693B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE14182/66A SE335359B (en)	1966-10-19	1966-10-19

Publications (2)

Publication Number	Publication Date
NL6714191A NL6714191A (en)	1968-04-22
NL151693B true NL151693B (en)	1976-12-15

Family

ID=20298669

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NL676714191A NL151693B (en)	1966-10-19	1967-10-19	PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH A BRONCHOSPASMOLYTIC ACTION CONTAINING A DERIVATIVE OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL AND OBTAINED UNDER APPLICATION OF THIS METHOD OF THE BRONCHOSPASMOLYTIC METHOD OF THE PREPARED METHOD A MEDICINAL 2-AMINO-1- (3,5-DIHYDROXYPHENYL) ETHANOL DERIVATIVE, USED AS AN ACTIVE INGREDIENT IN SUCH MEDICINAL PRODUCT.
NL7513854A NL7513854A (en)	1966-10-19	1975-11-27	METHOD OF PREPARATION OF A MEDICINAL PRODUCT WITH BRONCHOSPASMOLYTIC ACTION CONTAINING ONE OR SOME DERIVATIVES OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL AND THE USE OF THIS METHODS OF METHODS-BRONCHOSPASMOLYTIC ACTION AND PROCEDURE FOR PREPARING NOSPICID 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL DERIVATIVES.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NL7513854A NL7513854A (en)	1966-10-19	1975-11-27	METHOD OF PREPARATION OF A MEDICINAL PRODUCT WITH BRONCHOSPASMOLYTIC ACTION CONTAINING ONE OR SOME DERIVATIVES OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL AND THE USE OF THIS METHODS OF METHODS-BRONCHOSPASMOLYTIC ACTION AND PROCEDURE FOR PREPARING NOSPICID 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL DERIVATIVES.

Country Status (13)

Country	Link
AT (4)	AT288356B (en)
BE (1)	BE704932A (en)
CH (1)	CH510625A (en)
DE (2)	DE1643296C3 (en)
DK (2)	DK128491B (en)
ES (5)	ES346131A1 (en)
FI (1)	FI50786C (en)
FR (1)	FR8011M (en)
GB (1)	GB1199630A (en)
IT (1)	IT8048168A0 (en)
NL (2)	NL151693B (en)
NO (1)	NO120686B (en)
SE (1)	SE335359B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4138581A (en)	1969-04-01	1979-02-06	Sterling Drugs Inc.	3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
CY1273A (en)	1980-07-09	1985-03-08	Draco Ab	1-(dihydroxyphenyl)-2-amino-ethanol derivatives;preparation,compositions and intermediates
EP0046144B1 (en) *	1980-07-09	1984-04-11	Aktiebolaget Draco	Therapeutically active derivatives of phenylethanol amines
US4853381A (en) *	1984-04-17	1989-08-01	Glaxo Group Limited	Ethanolamine compounds
US4581225A (en) *	1984-04-25	1986-04-08	Eli Lilly And Company	Sustained release intranasal formulation and method of use thereof
EP0213108A3 (en) *	1985-06-26	1987-07-15	Kurt Dr. Burghart	Pharmaceutical preparation containing an antihypotonic as the active agent
WO2013081565A1 (en)	2011-11-21	2013-06-06	Mahmut Bilgic	Pharmaceutical compositions comprising roflumilast and terbutaline
WO2014108449A1 (en)	2013-01-08	2014-07-17	Atrogi Ab	A screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018182546A1 (en)	2017-03-27	2018-10-04	İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi	Stabilized pharmaceutical syrup composition comprising terbutaline sulphate and ambroxol hydrochloride
GB201714736D0 (en)	2017-09-13	2017-10-25	Atrogi Ab	New compounds and uses
GB201714740D0 (en)	2017-09-13	2017-10-25	Atrogi Ab	New compounds and uses
GB201714734D0 (en)	2017-09-13	2017-10-25	Atrogi Ab	New compounds and uses
GB201714745D0 (en)	2017-09-13	2017-10-25	Atrogi Ab	New compounds and uses
CN110057932B (en) *	2019-04-22	2022-03-15	上海旭东海普药业有限公司	Method for analyzing terbutaline sulfate related substances by high performance liquid chromatography
CN111440078A (en) *	2020-04-26	2020-07-24	梯尔希（南京）药物研发有限公司	Preparation method of terbutaline derivative
CN113264839B (en) *	2021-04-27	2022-08-30	苏州弘森药业股份有限公司	Method for preparing levo-terbutaline by using chiral prosthetic group
GB202205895D0 (en)	2022-04-22	2022-06-08	Atrogi Ab	New medical uses

1966
- 1966-10-19 SE SE14182/66A patent/SE335359B/xx unknown
1967
- 1967-10-10 AT AT941969A patent/AT288356B/en not_active IP Right Cessation
- 1967-10-10 AT AT915967A patent/AT286964B/en not_active IP Right Cessation
- 1967-10-10 AT AT09420/69A patent/AT287678B/en active
- 1967-10-10 AT AT09421/69A patent/AT287679B/en active
- 1967-10-11 BE BE704932D patent/BE704932A/xx not_active IP Right Cessation
- 1967-10-12 CH CH1425567A patent/CH510625A/en not_active IP Right Cessation
- 1967-10-16 ES ES346131A patent/ES346131A1/en not_active Expired
- 1967-10-17 DE DE1643296A patent/DE1643296C3/en not_active Expired
- 1967-10-17 FR FR124741A patent/FR8011M/fr not_active Expired
- 1967-10-17 DE DE1793759A patent/DE1793759C3/en not_active Expired
- 1967-10-18 NO NO170180A patent/NO120686B/no unknown
- 1967-10-18 DK DK518567AA patent/DK128491B/en unknown
- 1967-10-18 GB GB47505/67A patent/GB1199630A/en not_active Expired
- 1967-10-19 FI FI672811A patent/FI50786C/en active
- 1967-10-19 NL NL676714191A patent/NL151693B/en not_active IP Right Cessation
1968
- 1968-12-14 ES ES361433A patent/ES361433A1/en not_active Expired
- 1968-12-14 ES ES361429A patent/ES361429A1/en not_active Expired
- 1968-12-14 ES ES361431A patent/ES361431A1/en not_active Expired
- 1968-12-14 ES ES361432A patent/ES361432A1/en not_active Expired
1975
- 1975-11-27 NL NL7513854A patent/NL7513854A/en unknown
1976
- 1976-10-18 DK DK468876A patent/DK468876A/en unknown
1980
- 1980-03-14 IT IT8048168A patent/IT8048168A0/en unknown

Also Published As

Publication number	Publication date
AT287679B (en)	1971-02-10
ES361433A1 (en)	1970-11-01
SE335359B (en)	1971-05-24
FI50786B (en)	1976-03-31
AT286964B (en)	1971-01-11
ES361431A1 (en)	1970-11-01
DE1793759A1 (en)	1973-08-16
DE1643296A1 (en)	1971-09-30
NL7513854A (en)	1976-03-31
GB1199630A (en)	1970-07-22
ES361429A1 (en)	1970-11-01
CH510625A (en)	1971-07-31
DK128491B (en)	1974-05-13
ES361432A1 (en)	1970-11-01
DE1793759C3 (en)	1979-01-11
FI50786C (en)	1976-07-12
NO120686B (en)	1970-11-23
DE1643296C3 (en)	1974-06-12
NL6714191A (en)	1968-04-22
DK468876A (en)	1976-10-18
AT287678B (en)	1971-02-10
AT288356B (en)	1971-03-10
DE1793759B2 (en)	1978-05-11
IT8048168A0 (en)	1980-03-14
DE1643296B2 (en)	1973-10-25
BE704932A (en)	1968-02-15
ES346131A1 (en)	1969-05-16
FR8011M (en)	1970-07-27

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Legal Events

Date	Code	Title	Description
1987-10-31	NL80	Information provided on patent owner name for an already discontinued patent	Owner name: DRACO
1987-12-16	V4	Discontinued because of reaching the maximum lifetime of a patent