NL143927B - Werkwijze voor de bereiding van benzodiazepineverbindingen. - Google Patents

Werkwijze voor de bereiding van benzodiazepineverbindingen.

Info

Publication number
NL143927B
NL143927B NL696908658A NL6908658A NL143927B NL 143927 B NL143927 B NL 143927B NL 696908658 A NL696908658 A NL 696908658A NL 6908658 A NL6908658 A NL 6908658A NL 143927 B NL143927 B NL 143927B
Authority
NL
Netherlands
Prior art keywords
preparation
benzodiazepine compounds
benzodiazepine
compounds
Prior art date
Application number
NL696908658A
Other languages
English (en)
Dutch (nl)
Other versions
NL6908658A (xx
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL6908658A publication Critical patent/NL6908658A/xx
Publication of NL143927B publication Critical patent/NL143927B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
    • D06P3/80—Inorganic fibres
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
    • D06P3/82—Textiles which contain different kinds of fibres
    • D06P3/854—Textiles which contain different kinds of fibres containing modified or unmodified fibres, i.e. containing the same type of fibres having different characteristics, e.g. twisted and not-twisted fibres

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL696908658A 1968-06-12 1969-06-06 Werkwijze voor de bereiding van benzodiazepineverbindingen. NL143927B (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73625068A 1968-06-12 1968-06-12
US80346169A 1969-02-28 1969-02-28

Publications (2)

Publication Number Publication Date
NL6908658A NL6908658A (xx) 1969-12-16
NL143927B true NL143927B (nl) 1974-11-15

Family

ID=27113017

Family Applications (3)

Application Number Title Priority Date Filing Date
NL696908658A NL143927B (nl) 1968-06-12 1969-06-06 Werkwijze voor de bereiding van benzodiazepineverbindingen.
NL6908866A NL6908866A (xx) 1968-06-12 1969-06-11
NL6908966A NL6908966A (xx) 1968-06-12 1969-06-12

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL6908866A NL6908866A (xx) 1968-06-12 1969-06-11
NL6908966A NL6908966A (xx) 1968-06-12 1969-06-12

Country Status (12)

Country Link
US (1) US3546212A (xx)
AT (2) AT289125B (xx)
BE (1) BE734376A (xx)
CA (1) CA950453A (xx)
CH (3) CH550185A (xx)
DE (1) DE1929910A1 (xx)
ES (1) ES368239A1 (xx)
FR (1) FR2010744A1 (xx)
GB (1) GB1239380A (xx)
IE (1) IE33286B1 (xx)
NL (3) NL143927B (xx)
SE (1) SE347510B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723414A (en) * 1970-02-13 1973-03-27 Schering Corp 1-polyfluoroalkyl benzodiazepines
US3896109A (en) * 1971-09-30 1975-07-22 Upjohn Co 2,3-dehydro-1h-1,4-benzodiazepines
US4083948A (en) * 1977-04-04 1978-04-11 Hoffmann-La Roche, Inc. Benzodiazepine radioimmunoassay using I125-label
SE7900456L (sv) * 1978-05-31 1979-07-20 Ferrosan As Bensodiazeptinkoncentrationsbestemning
DE3124013A1 (de) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3621551C1 (en) * 1986-06-27 1987-07-02 Eckard 5810 Witten De Feller Cutting tool for lathe - has carrier arm and screw cooperating to retain lower packer plate and upper cutting insert in tool
DE3836538A1 (de) * 1988-10-27 1990-05-03 Christian Rinke Verpackungsbehaelter, insbesondere flasche
GB8917222D0 (en) * 1989-07-27 1989-09-13 Schering Agrochemicals Ltd Herbicides
CA2147275A1 (en) * 1992-10-16 1994-04-28 Hirokazu Yamada Pyrimidine derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones

Also Published As

Publication number Publication date
US3546212A (en) 1970-12-08
AT289125B (de) 1971-04-13
AT299960B (de) 1972-07-10
BE734376A (xx) 1969-12-11
IE33286L (en) 1969-12-12
GB1239380A (xx) 1971-07-14
CA950453A (en) 1974-07-02
DE1929910A1 (de) 1970-01-02
NL6908866A (xx) 1969-12-22
IE33286B1 (en) 1974-05-15
ES368239A1 (es) 1971-06-16
CH523898A (de) 1972-06-15
FR2010744A1 (xx) 1970-02-20
NL6908966A (xx) 1969-12-16
NL6908658A (xx) 1969-12-16
CH550185A (de) 1974-06-14
SE347510B (xx) 1972-08-07
CH523267A (de) 1972-05-31

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Legal Events

Date Code Title Description
VJC Lapsed due to non-payment of the due maintenance fee for the patent or patent application
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: HOFFMANN