NL1033562A1 - Tetrahydropyridoazepine-8-onen en verwante verbindingen voor de behandeling van schizofrenie. - Google Patents
Tetrahydropyridoazepine-8-onen en verwante verbindingen voor de behandeling van schizofrenie.Info
- Publication number
- NL1033562A1 NL1033562A1 NL1033562A NL1033562A NL1033562A1 NL 1033562 A1 NL1033562 A1 NL 1033562A1 NL 1033562 A NL1033562 A NL 1033562A NL 1033562 A NL1033562 A NL 1033562A NL 1033562 A1 NL1033562 A1 NL 1033562A1
- Authority
- NL
- Netherlands
- Prior art keywords
- tetrahydropyridoazepine
- schizophrenia
- ones
- treatment
- related compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66744705P | 2005-04-01 | 2005-04-01 | |
| US66744705 | 2005-04-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1033562A1 true NL1033562A1 (nl) | 2007-06-21 |
| NL1033562C2 NL1033562C2 (nl) | 2007-10-23 |
Family
ID=36763625
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1031489A NL1031489C2 (nl) | 2005-04-01 | 2006-03-31 | Tetrahydropyridoazepine-8-onen en verwante verbindingen voor de behandeling van schizofrenie. |
| NL1033562A NL1033562C2 (nl) | 2005-04-01 | 2007-03-20 | Tetrahydropyridoazepine-8-onen en verwante verbindingen voor de behandeling van schizofrenie. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1031489A NL1031489C2 (nl) | 2005-04-01 | 2006-03-31 | Tetrahydropyridoazepine-8-onen en verwante verbindingen voor de behandeling van schizofrenie. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20060234997A1 (nl) |
| EP (1) | EP1869041A1 (nl) |
| JP (1) | JP4109709B1 (nl) |
| KR (1) | KR20070112228A (nl) |
| CN (1) | CN101189237A (nl) |
| AP (1) | AP2007004160A0 (nl) |
| AR (1) | AR053835A1 (nl) |
| AU (1) | AU2006228426A1 (nl) |
| BR (1) | BRPI0607918A2 (nl) |
| CA (1) | CA2603049A1 (nl) |
| CR (1) | CR9407A (nl) |
| DO (1) | DOP2006000071A (nl) |
| EA (1) | EA200701856A1 (nl) |
| GT (1) | GT200600130A (nl) |
| IL (1) | IL185770A0 (nl) |
| MA (1) | MA29989B1 (nl) |
| MX (1) | MX2007012083A (nl) |
| NL (2) | NL1031489C2 (nl) |
| NO (1) | NO20075477L (nl) |
| PE (1) | PE20061196A1 (nl) |
| TN (1) | TNSN07366A1 (nl) |
| TW (1) | TW200714282A (nl) |
| UY (1) | UY29447A1 (nl) |
| WO (1) | WO2006103559A1 (nl) |
| ZA (1) | ZA200708033B (nl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007116265A1 (en) * | 2006-03-31 | 2007-10-18 | Pfizer Products Inc. | Process for making a tetrahydro-pyridoazepin-8-one compound |
| US8674790B2 (en) | 2009-12-28 | 2014-03-18 | Seiko Epson Corporation | Surface acoustic wave device, oscillator, module apparatus |
| WO2012003418A2 (en) | 2010-07-02 | 2012-01-05 | The University Of North Carolina At Chapel Hill | Functionally selective ligands of dopamine d2 receptors |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2017122116A1 (en) | 2016-01-15 | 2017-07-20 | Pfizer Inc. | 6,7,8,9-TETRAHYDRO-5H-PYRIDO[2,3-d]AZEPINE DOPAMINE D3 LIGANDS |
| CN109071504B (zh) | 2016-02-05 | 2022-03-08 | 戴纳立制药公司 | 受体相互作用蛋白激酶1的抑制剂 |
| HRP20220636T1 (hr) | 2016-12-09 | 2022-07-22 | Denali Therapeutics Inc. | Spojevi korisni kao inhibitori ripk1 |
| WO2022212538A1 (en) * | 2021-03-31 | 2022-10-06 | Blueprint Medicines Corporation | Diazepanone-fused pyrimidine compounds, compositions and medicinal applications thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2960178D1 (en) * | 1978-06-06 | 1981-04-09 | Hoechst Ag | New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation |
| JPS57193461A (en) * | 1981-05-22 | 1982-11-27 | Otsuka Pharmaceut Co Ltd | Benzazepine derivative |
| DK588486A (da) * | 1985-12-09 | 1987-06-10 | Otsuka Pharma Co Ltd | Anvendelse af en forbindelse til behandling af hypoxi |
| US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5350747A (en) * | 1989-07-07 | 1994-09-27 | Pfizer Inc | Heteroaryl piperazine antipsychotic agents |
| MX9201991A (es) * | 1991-05-02 | 1992-11-01 | Jonh Wyeth & Brother Limited | Derivados de piperazina y procedimiento para su preparacion. |
| US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
| FR2699918B1 (fr) * | 1992-12-30 | 1995-03-17 | Pf Medicament | Ligands sélectifs des récepteurs 5HY1D-5HT1B dérivés d'indole-pipérazine utiles comme médicaments. |
| US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| DE19747063A1 (de) * | 1997-10-24 | 1999-04-29 | Basf Ag | 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung |
| US7160888B2 (en) * | 2003-08-22 | 2007-01-09 | Warner Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia |
-
2006
- 2006-03-20 CN CNA2006800197403A patent/CN101189237A/zh active Pending
- 2006-03-20 AP AP2007004160A patent/AP2007004160A0/xx unknown
- 2006-03-20 MX MX2007012083A patent/MX2007012083A/es unknown
- 2006-03-20 BR BRPI0607918-0A patent/BRPI0607918A2/pt not_active Application Discontinuation
- 2006-03-20 WO PCT/IB2006/000900 patent/WO2006103559A1/en active Application Filing
- 2006-03-20 EA EA200701856A patent/EA200701856A1/ru unknown
- 2006-03-20 EP EP06727493A patent/EP1869041A1/en not_active Withdrawn
- 2006-03-20 AU AU2006228426A patent/AU2006228426A1/en not_active Abandoned
- 2006-03-20 JP JP2008503619A patent/JP4109709B1/ja not_active Expired - Fee Related
- 2006-03-20 KR KR1020077022373A patent/KR20070112228A/ko not_active Application Discontinuation
- 2006-03-20 CA CA002603049A patent/CA2603049A1/en not_active Abandoned
- 2006-03-28 DO DO2006000071A patent/DOP2006000071A/es unknown
- 2006-03-30 PE PE2006000353A patent/PE20061196A1/es not_active Application Discontinuation
- 2006-03-30 AR ARP060101253A patent/AR053835A1/es unknown
- 2006-03-30 UY UY29447A patent/UY29447A1/es not_active Application Discontinuation
- 2006-03-31 TW TW095111562A patent/TW200714282A/zh unknown
- 2006-03-31 NL NL1031489A patent/NL1031489C2/nl not_active IP Right Cessation
- 2006-03-31 US US11/395,931 patent/US20060234997A1/en not_active Abandoned
- 2006-03-31 GT GT200600130A patent/GT200600130A/es unknown
-
2007
- 2007-03-20 NL NL1033562A patent/NL1033562C2/nl not_active IP Right Cessation
- 2007-09-06 IL IL185770A patent/IL185770A0/en unknown
- 2007-09-18 ZA ZA200708033A patent/ZA200708033B/xx unknown
- 2007-09-28 TN TNP2007000366A patent/TNSN07366A1/fr unknown
- 2007-10-01 CR CR9407A patent/CR9407A/es not_active Application Discontinuation
- 2007-10-01 MA MA30264A patent/MA29989B1/fr unknown
- 2007-10-30 NO NO20075477A patent/NO20075477L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL1033562C2 (nl) | 2007-10-23 |
| UY29447A1 (es) | 2006-10-31 |
| IL185770A0 (en) | 2008-01-06 |
| ZA200708033B (en) | 2008-11-26 |
| PE20061196A1 (es) | 2006-12-16 |
| JP2008534574A (ja) | 2008-08-28 |
| GT200600130A (es) | 2007-02-14 |
| WO2006103559A1 (en) | 2006-10-05 |
| BRPI0607918A2 (pt) | 2009-10-20 |
| EA200701856A1 (ru) | 2008-02-28 |
| JP4109709B1 (ja) | 2008-07-02 |
| MX2007012083A (es) | 2007-11-20 |
| CA2603049A1 (en) | 2006-10-05 |
| EP1869041A1 (en) | 2007-12-26 |
| DOP2006000071A (es) | 2006-10-15 |
| NL1031489C2 (nl) | 2007-04-02 |
| CN101189237A (zh) | 2008-05-28 |
| NO20075477L (no) | 2007-12-13 |
| AP2007004160A0 (en) | 2007-10-31 |
| NL1031489A1 (nl) | 2006-10-03 |
| AR053835A1 (es) | 2007-05-23 |
| KR20070112228A (ko) | 2007-11-22 |
| TNSN07366A1 (fr) | 2008-12-31 |
| AU2006228426A1 (en) | 2006-10-05 |
| CR9407A (es) | 2008-01-29 |
| MA29989B1 (fr) | 2008-12-01 |
| US20060234997A1 (en) | 2006-10-19 |
| TW200714282A (en) | 2007-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AD1A | A request for search or an international type search has been filed | ||
| PD2A | A request for search or an international type search has been filed | ||
| VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20091001 |