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Publication of MY165097ApublicationCriticalpatent/MY165097A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
THE INVENTION RELATES TO A COMBINATION WHICH COMPRISES: (A) COMPOUND A ((R)-3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANENITRILE) OF FORMULA (A): OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF; AND (B) COMPOUND B (N-HYDROXY-3-[4-[[[2-(2-METHYL-1H-INDOL-3-YL)-ETHYL]-AMINO]METHYL]PHENYL]-2E-2-PROPENAMIDE) OF FORMULA (B): OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF; FOR SIMULTANEOUS, CONCURRENT, SEPARATE OR SEQUENTIAL USE, ESPECIALLY FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES. THE INVENTION ALSO RELATES TO PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH A COMBINATION AND TO A METHOD OF TREATING PROLIFERATIVE DISEASES, IN A MAMMAL, PARTICULARLY A HUMAN, WITH SUCH A COMBINATION. THE PRESENT INVENTION FURTHER ALSO RELATES TO A COMMERCIAL PACKAGE OR PRODUCT COMPRISING SUCH A COMBINATION.
MYPI2013004204A2011-06-142012-06-13Combination of panobinostat and ruxolitinib in the treatment of cancer such as a myeloproliferative neoplasm
MY165097A
(en)
N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy.
Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquin oline derivatives, pharmaceutical compositions containing them, and their use in therapy.