MY150861A - Neutron activated 153sm labelled microspheres - Google Patents

Neutron activated 153sm labelled microspheres

Info

Publication number
MY150861A
MY150861A MYPI2012700480A MY150861A MY 150861 A MY150861 A MY 150861A MY PI2012700480 A MYPI2012700480 A MY PI2012700480A MY 150861 A MY150861 A MY 150861A
Authority
MY
Malaysia
Prior art keywords
microspheres
labelled
neutron activated
labelled microspheres
neutron
Prior art date
Application number
Inventor
Basri Johan Jeet Abdullah
Yeong Chai Hong
Chung Lip Yong
Ng Kwan Hoong
Original Assignee
Univ Malaya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Malaya filed Critical Univ Malaya
Priority to MYPI2012700480 priority Critical patent/MY150861A/en
Priority to PCT/MY2013/000147 priority patent/WO2014030993A1/en
Publication of MY150861A publication Critical patent/MY150861A/en

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00—Radioactive sources
    • G21G4/04—Radioactive sources other than neutron sources
    • G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • A61K51/1251—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/06—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by neutron irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to a method of preparation of 153Sm labelled microspheres, comprising the steps of incorporating a 152Sm compound into insoluble ion-exchange resin or glass beads and subsequently performing neutron activation of the incorporated samarium microspheres. It further includes radioactive microspheres containing 153SmCl3 or a hydrate thereof and the clinical use of such radiolabelled microspheres.
MYPI2012700480 2012-07-18 2012-07-18 Neutron activated 153sm labelled microspheres MY150861A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MYPI2012700480 MY150861A (en) 2012-07-18 2012-07-18 Neutron activated 153sm labelled microspheres
PCT/MY2013/000147 WO2014030993A1 (en) 2012-07-18 2013-08-16 Neutron activated 153sm labelled microspheres

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2012700480 MY150861A (en) 2012-07-18 2012-07-18 Neutron activated 153sm labelled microspheres

Publications (1)

Publication Number Publication Date
MY150861A true MY150861A (en) 2014-03-06

Family

ID=49162192

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2012700480 MY150861A (en) 2012-07-18 2012-07-18 Neutron activated 153sm labelled microspheres

Country Status (2)

Country Link
MY (1) MY150861A (en)
WO (1) WO2014030993A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2859971C (en) * 2011-12-21 2020-08-04 Isotherapeutics Group, Llc Radioactive compositions and methods for their therapeutic use
EP3645058A4 (en) * 2017-06-28 2021-05-12 The Regents of The University of California Composite embolization beads

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
WO1994026755A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes, a process for their preparation, and their conjugates, for use as radiopharmaceuticals
KR20100135312A (en) * 2008-04-24 2010-12-24 디 오스트레일리언 내셔널 유니버시티 Methods for radiolabelling synthetic polymers

Also Published As

Publication number Publication date
WO2014030993A1 (en) 2014-02-27

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