MXPA05002955A - Test strip and method for determining ldl cholesterol concentration from whole blood. - Google Patents
Test strip and method for determining ldl cholesterol concentration from whole blood.Info
- Publication number
- MXPA05002955A MXPA05002955A MXPA05002955A MXPA05002955A MXPA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A
- Authority
- MX
- Mexico
- Prior art keywords
- concentration
- test strip
- ldl cholesterol
- whole blood
- panel
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
- G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A dry phase test strip (20) and method are provided for determining the concentration of LDL in whole blood or plasma. The inventive test strip (20) includes one stack (92) or panel that measures concentration of total cholesterol and another stack (94) or panel that measures concentration of the sum total of HDL, VLDL and chylomicrons ("non-LDLs"). The difference between the values just noted is equal to the concentration of LDL cholesterol. Dry phase test strips (20) of the present invention function at room temperature and all test results are produced from pseudo-endpoint reflectance measurements such that the test method need not be timed. Also disclosed is the capability for an improved lipid panel that provides concentration in a blood sample of HDL, total cholesterol and LDL cholesterol without relying upon the Friedewald equation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41120902P | 2002-09-16 | 2002-09-16 | |
PCT/US2003/029102 WO2004025265A2 (en) | 2002-09-16 | 2003-09-16 | Test strip and method for determining ldl cholesterol concentration from whole blood |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05002955A true MXPA05002955A (en) | 2005-10-18 |
Family
ID=31994248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05002955A MXPA05002955A (en) | 2002-09-16 | 2003-09-16 | Test strip and method for determining ldl cholesterol concentration from whole blood. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1540353A4 (en) |
AU (1) | AU2003272453A1 (en) |
CA (1) | CA2499058A1 (en) |
MX (1) | MXPA05002955A (en) |
WO (1) | WO2004025265A2 (en) |
ZA (1) | ZA200502214B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10204606C1 (en) | 2002-01-18 | 2003-10-16 | Cholestech Corp | Device and method for high density lipoproteins |
EP1357383B1 (en) | 2002-04-09 | 2005-11-09 | Cholestech Corporation | High-density lipoprotein assay device and method |
US7772007B2 (en) | 2004-04-02 | 2010-08-10 | Cholestech Corporation | Assay device for direct measurement of LDL cholesterol |
US7824879B2 (en) | 2007-01-09 | 2010-11-02 | Cholestech Corporation | Device and method for measuring LDL-associated cholesterol |
CN101657546B (en) * | 2007-09-05 | 2013-01-02 | 爱科来株式会社 | Method of measuring low density lipoprotein (LDL) cholesterol and test piece for measuring ldl cholesterol |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5132086A (en) * | 1990-02-06 | 1992-07-21 | Chemtrak Corporation | Non-instrumented cholesterol assay |
US5135716A (en) * | 1989-07-12 | 1992-08-04 | Kingston Diagnostics, L.P. | Direct measurement of HDL cholesterol via dry chemistry strips |
US5460974A (en) * | 1992-10-13 | 1995-10-24 | Miles Inc. | Method of assaying whole blood for HDL cholesterol |
JP3193634B2 (en) * | 1996-05-29 | 2001-07-30 | 第一化学薬品株式会社 | LDL cholesterol determination method |
JP3441993B2 (en) * | 1999-01-27 | 2003-09-02 | 松下電器産業株式会社 | Cholesterol sensor |
US6524864B2 (en) * | 2000-12-28 | 2003-02-25 | Aurora L. Fernandez Decastro | Test strip for simultaneous detection of a plurality of analytes |
-
2003
- 2003-09-16 MX MXPA05002955A patent/MXPA05002955A/en not_active Application Discontinuation
- 2003-09-16 CA CA002499058A patent/CA2499058A1/en not_active Abandoned
- 2003-09-16 EP EP03754634A patent/EP1540353A4/en not_active Withdrawn
- 2003-09-16 WO PCT/US2003/029102 patent/WO2004025265A2/en not_active Application Discontinuation
- 2003-09-16 AU AU2003272453A patent/AU2003272453A1/en not_active Abandoned
-
2005
- 2005-03-16 ZA ZA200502214A patent/ZA200502214B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2003272453A1 (en) | 2004-04-30 |
WO2004025265A3 (en) | 2004-07-01 |
ZA200502214B (en) | 2006-05-31 |
EP1540353A4 (en) | 2007-01-24 |
EP1540353A2 (en) | 2005-06-15 |
CA2499058A1 (en) | 2004-03-25 |
WO2004025265A2 (en) | 2004-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |