MXPA04005196A - Metodos para la purificacion de levofloxacina. - Google Patents
Metodos para la purificacion de levofloxacina.Info
- Publication number
- MXPA04005196A MXPA04005196A MXPA04005196A MXPA04005196A MXPA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A
- Authority
- MX
- Mexico
- Prior art keywords
- levofloxacin
- process according
- solvent
- purified
- acetonitrile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33431601P | 2001-11-29 | 2001-11-29 | |
US35493902P | 2002-02-11 | 2002-02-11 | |
US26296502A | 2002-10-03 | 2002-10-03 | |
US10/263,192 US7629458B2 (en) | 2001-10-03 | 2002-10-03 | Preparation of levofloxacin and hemihydrate thereof |
PCT/US2002/038182 WO2003045329A2 (en) | 2001-11-29 | 2002-11-27 | Methods for the purification of levofloxacin |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04005196A true MXPA04005196A (es) | 2005-11-23 |
Family
ID=31892240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04005196A MXPA04005196A (es) | 2001-11-29 | 2002-11-27 | Metodos para la purificacion de levofloxacina. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1460997A4 (is) |
JP (3) | JP2005527484A (is) |
CN (1) | CN1596256A (is) |
AU (1) | AU2002365416A1 (is) |
CA (1) | CA2466860A1 (is) |
HR (1) | HRP20040546A2 (is) |
HU (1) | HUP0500285A3 (is) |
IL (1) | IL162172A0 (is) |
IS (1) | IS7288A (is) |
MX (1) | MXPA04005196A (is) |
NO (1) | NO20042731L (is) |
PL (1) | PL374558A1 (is) |
WO (1) | WO2003045329A2 (is) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1992629A1 (en) | 2001-10-03 | 2008-11-19 | Teva Pharmaceutical Industries Ltd. | Preparation of levofloxacin and forms thereof |
CN1735620A (zh) * | 2002-12-16 | 2006-02-15 | 兰贝克赛实验室有限公司 | 纯的左氧氟沙星半水合物和它的制备方法 |
KR100704641B1 (ko) * | 2004-07-21 | 2007-04-06 | 주식회사유한양행 | 고순도의 레보플록사신 제조방법 |
JP2006273718A (ja) * | 2005-03-28 | 2006-10-12 | Shiono Chemical Co Ltd | レボフロキサシン・1/2水和物の製法 |
CN1321121C (zh) * | 2005-04-21 | 2007-06-13 | 浙江医药股份有限公司新昌制药厂 | 左氧氟沙星制备及后处理方法 |
US7964723B2 (en) | 2008-08-02 | 2011-06-21 | Apeloa-Kangyu | And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate |
CN102070650B (zh) * | 2011-01-28 | 2012-06-27 | 山东省药品检验所 | 左氧氟沙星-n-氧化物的制备方法 |
US20120251685A1 (en) * | 2011-04-04 | 2012-10-04 | Martek Biosciences Corporation | Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same |
CN105823851A (zh) * | 2015-12-15 | 2016-08-03 | 浙江海洋学院 | 一种检测海水中氧氟沙星对映体的方法 |
CN108218892A (zh) * | 2018-03-16 | 2018-06-29 | 乐山职业技术学院 | 一种左氧氟沙星的纯化方法 |
CN114507242B (zh) * | 2022-01-26 | 2023-05-19 | 上虞京新药业有限公司 | 高光学纯度左氧氟沙星的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO166131C (no) * | 1985-06-20 | 1991-06-05 | Daiichi Seiyaku Co | Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser. |
US5237060A (en) * | 1985-12-10 | 1993-08-17 | Bayer Aktiengesellschaft | Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids |
TW208013B (is) * | 1990-03-01 | 1993-06-21 | Daiichi Co Ltd | |
CA2125287A1 (en) * | 1992-10-07 | 1994-04-14 | Juan Carlos Carretero Gonzalvez | Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives |
KR0125115B1 (ko) * | 1994-03-22 | 1997-12-05 | 김은영 | (-)피페라진 벤즈옥사진 유도체의 제조방법 |
KR100309871B1 (ko) * | 1999-02-24 | 2001-10-29 | 윤종용 | (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법 |
EP1992629A1 (en) * | 2001-10-03 | 2008-11-19 | Teva Pharmaceutical Industries Ltd. | Preparation of levofloxacin and forms thereof |
-
2002
- 2002-11-27 IL IL16217202A patent/IL162172A0/xx unknown
- 2002-11-27 CN CNA028236440A patent/CN1596256A/zh active Pending
- 2002-11-27 PL PL02374558A patent/PL374558A1/xx not_active Application Discontinuation
- 2002-11-27 MX MXPA04005196A patent/MXPA04005196A/es not_active Application Discontinuation
- 2002-11-27 EP EP02791339A patent/EP1460997A4/en not_active Withdrawn
- 2002-11-27 CA CA002466860A patent/CA2466860A1/en not_active Abandoned
- 2002-11-27 HU HU0500285A patent/HUP0500285A3/hu unknown
- 2002-11-27 JP JP2003546834A patent/JP2005527484A/ja active Pending
- 2002-11-27 AU AU2002365416A patent/AU2002365416A1/en not_active Abandoned
- 2002-11-27 WO PCT/US2002/038182 patent/WO2003045329A2/en active Application Filing
-
2004
- 2004-05-27 IS IS7288A patent/IS7288A/is unknown
- 2004-06-15 HR HR20040546A patent/HRP20040546A2/hr not_active Application Discontinuation
- 2004-06-29 NO NO20042731A patent/NO20042731L/no not_active Application Discontinuation
-
2006
- 2006-05-01 JP JP2006127862A patent/JP2006219496A/ja not_active Withdrawn
-
2007
- 2007-08-22 JP JP2007216178A patent/JP2008007517A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IS7288A (is) | 2004-06-21 |
NO20042731L (no) | 2004-06-29 |
JP2006219496A (ja) | 2006-08-24 |
HUP0500285A2 (hu) | 2005-06-28 |
EP1460997A4 (en) | 2005-06-15 |
HUP0500285A3 (en) | 2009-03-30 |
CA2466860A1 (en) | 2003-06-05 |
IL162172A0 (en) | 2005-11-20 |
JP2008007517A (ja) | 2008-01-17 |
PL374558A1 (en) | 2005-10-31 |
WO2003045329A2 (en) | 2003-06-05 |
WO2003045329A3 (en) | 2004-02-19 |
AU2002365416A1 (en) | 2003-06-10 |
CN1596256A (zh) | 2005-03-16 |
HRP20040546A2 (en) | 2004-10-31 |
JP2005527484A (ja) | 2005-09-15 |
EP1460997A2 (en) | 2004-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |