MXPA04005196A - Metodos para la purificacion de levofloxacina. - Google Patents

Metodos para la purificacion de levofloxacina.

Info

Publication number
MXPA04005196A
MXPA04005196A MXPA04005196A MXPA04005196A MXPA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A MX PA04005196 A MXPA04005196 A MX PA04005196A
Authority
MX
Mexico
Prior art keywords
levofloxacin
process according
solvent
purified
acetonitrile
Prior art date
Application number
MXPA04005196A
Other languages
English (en)
Spanish (es)
Inventor
Gershon Noemi
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of MXPA04005196A publication Critical patent/MXPA04005196A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
MXPA04005196A 2001-11-29 2002-11-27 Metodos para la purificacion de levofloxacina. MXPA04005196A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof
PCT/US2002/038182 WO2003045329A2 (en) 2001-11-29 2002-11-27 Methods for the purification of levofloxacin

Publications (1)

Publication Number Publication Date
MXPA04005196A true MXPA04005196A (es) 2005-11-23

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04005196A MXPA04005196A (es) 2001-11-29 2002-11-27 Metodos para la purificacion de levofloxacina.

Country Status (13)

Country Link
EP (1) EP1460997A4 (is)
JP (3) JP2005527484A (is)
CN (1) CN1596256A (is)
AU (1) AU2002365416A1 (is)
CA (1) CA2466860A1 (is)
HR (1) HRP20040546A2 (is)
HU (1) HUP0500285A3 (is)
IL (1) IL162172A0 (is)
IS (1) IS7288A (is)
MX (1) MXPA04005196A (is)
NO (1) NO20042731L (is)
PL (1) PL374558A1 (is)
WO (1) WO2003045329A2 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1992629A1 (en) 2001-10-03 2008-11-19 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and forms thereof
CN1735620A (zh) * 2002-12-16 2006-02-15 兰贝克赛实验室有限公司 纯的左氧氟沙星半水合物和它的制备方法
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
JP2006273718A (ja) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd レボフロキサシン・１／２水和物の製法
CN1321121C (zh) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 左氧氟沙星制备及后处理方法
US7964723B2 (en) 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (zh) * 2011-01-28 2012-06-27 山东省药品检验所 左氧氟沙星-n-氧化物的制备方法
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (zh) * 2015-12-15 2016-08-03 浙江海洋学院 一种检测海水中氧氟沙星对映体的方法
CN108218892A (zh) * 2018-03-16 2018-06-29 乐山职业技术学院 一种左氧氟沙星的纯化方法
CN114507242B (zh) * 2022-01-26 2023-05-19 上虞京新药业有限公司 高光学纯度左氧氟沙星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO166131C (no) * 1985-06-20 1991-06-05 Daiichi Seiyaku Co Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (is) * 1990-03-01 1993-06-21 Daiichi Co Ltd
CA2125287A1 (en) * 1992-10-07 1994-04-14 Juan Carlos Carretero Gonzalvez Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
EP1992629A1 (en) * 2001-10-03 2008-11-19 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and forms thereof

Also Published As

Publication number Publication date
IS7288A (is) 2004-06-21
NO20042731L (no) 2004-06-29
JP2006219496A (ja) 2006-08-24
HUP0500285A2 (hu) 2005-06-28
EP1460997A4 (en) 2005-06-15
HUP0500285A3 (en) 2009-03-30
CA2466860A1 (en) 2003-06-05
IL162172A0 (en) 2005-11-20
JP2008007517A (ja) 2008-01-17
PL374558A1 (en) 2005-10-31
WO2003045329A2 (en) 2003-06-05
WO2003045329A3 (en) 2004-02-19
AU2002365416A1 (en) 2003-06-10
CN1596256A (zh) 2005-03-16
HRP20040546A2 (en) 2004-10-31
JP2005527484A (ja) 2005-09-15
EP1460997A2 (en) 2004-09-29

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