MXPA04003544A - Benzotriazepinas como ligandos del receptor de gastrina y colecistocinina. - Google Patents

Benzotriazepinas como ligandos del receptor de gastrina y colecistocinina.

Info

Publication number
MXPA04003544A
MXPA04003544A MXPA04003544A MXPA04003544A MXPA04003544A MX PA04003544 A MXPA04003544 A MX PA04003544A MX PA04003544 A MXPA04003544 A MX PA04003544A MX PA04003544 A MXPA04003544 A MX PA04003544A MX PA04003544 A MXPA04003544 A MX PA04003544A
Authority
MX
Mexico
Prior art keywords
gastrin
benzotriazepines
receptor ligands
cholecystokinin receptor
cholecystokinin
Prior art date
Application number
MXPA04003544A
Other languages
English (en)
Inventor
Trevor Wright Paul
Original Assignee
Black James Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0127262A external-priority patent/GB0127262D0/en
Priority claimed from GB0219051A external-priority patent/GB0219051D0/en
Application filed by Black James Foundation filed Critical Black James Foundation
Publication of MXPA04003544A publication Critical patent/MXPA04003544A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Esta invencion se relaciona con un compuesto de formula (I) en donde: W es N o N+ -O-; y R1 a R5 son como se definen en la descripcion, para uso para el tratamiento de trastornos relacionados con gastrina.
MXPA04003544A 2001-11-13 2002-11-12 Benzotriazepinas como ligandos del receptor de gastrina y colecistocinina. MXPA04003544A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0127262A GB0127262D0 (en) 2001-11-13 2001-11-13 Gastrin and cholecystokinin receptor ligands (VI)
GB0219051A GB0219051D0 (en) 2002-08-15 2002-08-15 Gastrin and cholecystokinin receptor ligands (V1-2)
PCT/GB2002/005121 WO2003041714A1 (en) 2001-11-13 2002-11-12 Benzotriazepines as gastrin and cholecystokinin receptor ligands

Publications (1)

Publication Number Publication Date
MXPA04003544A true MXPA04003544A (es) 2004-07-22

Family

ID=26246762

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003544A MXPA04003544A (es) 2001-11-13 2002-11-12 Benzotriazepinas como ligandos del receptor de gastrina y colecistocinina.

Country Status (20)

Country Link
US (1) US20060003993A1 (es)
EP (1) EP1443934B1 (es)
JP (1) JP2005513013A (es)
KR (1) KR20050044852A (es)
CN (1) CN100348196C (es)
AR (1) AR037359A1 (es)
AT (1) ATE293449T1 (es)
BR (1) BR0213317A (es)
CA (1) CA2466955A1 (es)
DE (1) DE60203818T2 (es)
ES (1) ES2240815T3 (es)
HU (1) HUP0402068A3 (es)
IL (1) IL161330A0 (es)
MX (1) MXPA04003544A (es)
NO (1) NO20042452L (es)
NZ (1) NZ532213A (es)
PL (1) PL369568A1 (es)
RU (1) RU2304438C2 (es)
TW (1) TW200303205A (es)
WO (1) WO2003041714A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004101533A1 (en) * 2003-05-12 2004-11-25 Janssen Pharmaceutica, N.V. 1, 3, 4-benzotriazepin-2-one salts and their use as cck receptor ligands
US20050043359A1 (en) * 2003-08-20 2005-02-24 The Procter & Gamble Company Kit for treatment of upper gastrointestinal tract conditions
WO2005074931A1 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag Pharmaceutical combinations comprising (s) -pantoprazole
GB0425196D0 (en) * 2004-11-15 2004-12-15 Black James Foundation Gastrin and cholecystokinin receptor ligands
ES2442865T3 (es) * 2005-09-16 2014-02-14 Janssen Pharmaceutica N.V. Procedimiento para la preparación de derivados de venzo[E][1,2,4]triazepina-2-ona
GB0610018D0 (en) * 2006-05-19 2006-06-28 James Black Foundation Benzotriazepinone derivatives
WO2007135417A1 (en) * 2006-05-19 2007-11-29 James Black Foundation Benzotriazepinone derivatives
US7863330B2 (en) 2006-06-14 2011-01-04 Rottapharm S.P.A. Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders
PL3071206T3 (pl) 2013-11-22 2022-01-17 CL BioSciences LLC Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie
GB201414116D0 (en) 2014-08-08 2014-09-24 Trio Medicines Ltd Benzodiazepine derivatives
GB201513979D0 (en) 2015-08-07 2015-09-23 Trio Medicines Ltd Synthesis of benzodiazepine derivatives
US11097031B2 (en) 2016-08-01 2021-08-24 The Procter & Gamble Company Phase-stable, sprayable freshening compositions comprising suspended particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176008A (en) * 1962-09-11 1965-03-30 American Home Prod 5-phenyl-benzotriazepin-2-one compounds and their production
US5091381A (en) * 1991-04-12 1992-02-25 Biomeasure, Inc. 2H-1,3,4-benzotriazepin-2-ones
AU3247593A (en) * 1991-12-20 1993-07-28 Warner-Lambert Company Therapeutic combinations useful in the treatment of gastroesophageal reflux disease
US5378838A (en) * 1993-01-13 1995-01-03 Merck & Co., Inc. Benzodiazepine cholecystokinin antagonists

Also Published As

Publication number Publication date
WO2003041714A1 (en) 2003-05-22
BR0213317A (pt) 2004-10-13
EP1443934B1 (en) 2005-04-20
CN1585643A (zh) 2005-02-23
US20060003993A1 (en) 2006-01-05
AU2002341218B2 (en) 2007-03-15
TW200303205A (en) 2003-09-01
RU2004117880A (ru) 2005-04-20
HUP0402068A2 (hu) 2005-02-28
DE60203818D1 (de) 2005-05-25
HUP0402068A3 (en) 2005-09-28
RU2304438C2 (ru) 2007-08-20
KR20050044852A (ko) 2005-05-13
AR037359A1 (es) 2004-11-03
IL161330A0 (en) 2004-09-27
ATE293449T1 (de) 2005-05-15
CN100348196C (zh) 2007-11-14
EP1443934A1 (en) 2004-08-11
CA2466955A1 (en) 2003-05-22
NO20042452L (no) 2004-08-12
JP2005513013A (ja) 2005-05-12
NZ532213A (en) 2006-12-22
PL369568A1 (en) 2005-05-02
DE60203818T2 (de) 2006-01-26
ES2240815T3 (es) 2005-10-16

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