MXPA03010737A - Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion. - Google Patents

Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion.

Info

Publication number
MXPA03010737A
MXPA03010737A MXPA03010737A MXPA03010737A MXPA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A
Authority
MX
Mexico
Prior art keywords
depression
octanes
azabicyclo
aryl
treatment
Prior art date
Application number
MXPA03010737A
Other languages
English (en)
Inventor
Adam Matthew Gilbert
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA03010737A publication Critical patent/MXPA03010737A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invencion se refiere a compuestos de la formula (I), donde A, X, n, Ar1 y Ar2 estan definidas como en esta solicitud. Los compuestos pueden emplearse para tratar depresion. La invencion incluye tambien formulaciones conteniendo estos compuestos y procedimientos para preparar y usar compuestos inventivos.
MXPA03010737A 2001-05-25 2002-05-20 Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion. MXPA03010737A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29356301P 2001-05-25 2001-05-25
PCT/US2002/016008 WO2002096906A1 (en) 2001-05-25 2002-05-20 Aryl-8-azabicyclo[3.2.1]octanes for the treatment of depression

Publications (1)

Publication Number Publication Date
MXPA03010737A true MXPA03010737A (es) 2004-03-02

Family

ID=23129588

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03010737A MXPA03010737A (es) 2001-05-25 2002-05-20 Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion.

Country Status (14)

Country Link
US (1) US6632824B2 (es)
EP (1) EP1390364B1 (es)
JP (1) JP2004533459A (es)
CN (1) CN100408575C (es)
AR (1) AR035898A1 (es)
AT (1) ATE277924T1 (es)
BR (1) BR0209995A (es)
CA (1) CA2446532A1 (es)
DE (1) DE60201440T2 (es)
DK (1) DK1390364T3 (es)
ES (1) ES2227468T3 (es)
MX (1) MXPA03010737A (es)
TW (1) TW589312B (es)
WO (1) WO2002096906A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7873566B1 (en) 2001-11-20 2011-01-18 First Data Corporation Systems and methods for selectively accessing or using financial account data for subsequent risk determination
US20030130919A1 (en) * 2001-11-20 2003-07-10 Randy Templeton Systems and methods for selectively accessing financial account information
US7668776B1 (en) 2002-01-07 2010-02-23 First Data Corporation Systems and methods for selective use of risk models to predict financial risk
US7653590B1 (en) 2002-01-14 2010-01-26 First Data Corporation System and method for overturning of risk evaluation performed by risk model to control financial risk
EP1496058A1 (en) * 2003-07-09 2005-01-12 Boehringer Ingelheim Pharma GmbH & Co.KG Novel N-(heterobicycloalkanes)-substituted Indoles or heteroderivatives thereof
DE602006013828D1 (en) 2005-07-27 2010-06-02 Hoffmann La Roche 4-aryloxy-chinolin-derivate als 5-ht6-modulatoren
CN111217747B (zh) * 2020-03-17 2022-02-22 济南韶远医药技术有限公司 一种扑疟喹啉的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340936A (en) * 1991-02-04 1994-08-23 Hoechst-Roussel Pharmaceuticals Inc. 8-azabicyclo[3.2.1]octane methanone and corresponding oximes
US5789402A (en) 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5627196A (en) 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US6100275A (en) 1995-10-13 2000-08-08 Neurosearch A/S 8-azabicyclo[3.2.1.]oct-2-ene derivatives, their preparation and use
BR9611300A (pt) 1995-11-02 1999-06-15 Neurosearch As Derivados de tropano em fusão suas preparações e uso
US5912256A (en) 1996-06-20 1999-06-15 Eli Lilly And Company Compounds having effects on serotonin-related systems
AU4819099A (en) 1998-06-19 2000-01-05 Eli Lilly And Company Inhibition of serotonin reuptake
GB9815317D0 (en) * 1998-07-15 1998-09-16 Merck Sharp & Dohme Therapeutic agents
US6432976B1 (en) * 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
WO2001046187A1 (en) * 1999-12-20 2001-06-28 Eli Lilly And Company Azabicyclo[3.2.1]octane derivatives

Also Published As

Publication number Publication date
TW589312B (en) 2004-06-01
CA2446532A1 (en) 2002-12-05
JP2004533459A (ja) 2004-11-04
AR035898A1 (es) 2004-07-21
CN100408575C (zh) 2008-08-06
DE60201440D1 (de) 2004-11-04
ES2227468T3 (es) 2005-04-01
EP1390364A1 (en) 2004-02-25
US6632824B2 (en) 2003-10-14
BR0209995A (pt) 2004-04-06
US20030032645A1 (en) 2003-02-13
DE60201440T2 (de) 2006-02-23
DK1390364T3 (da) 2004-12-20
EP1390364B1 (en) 2004-09-29
CN1509287A (zh) 2004-06-30
WO2002096906A1 (en) 2002-12-05
ATE277924T1 (de) 2004-10-15

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