MXPA03008186A - Anti-thrombotic carboxylic acid amides, the production thereof and use of the same as medicaments. - Google Patents
Anti-thrombotic carboxylic acid amides, the production thereof and use of the same as medicaments.Info
- Publication number
- MXPA03008186A MXPA03008186A MXPA03008186A MXPA03008186A MXPA03008186A MX PA03008186 A MXPA03008186 A MX PA03008186A MX PA03008186 A MXPA03008186 A MX PA03008186A MX PA03008186 A MXPA03008186 A MX PA03008186A MX PA03008186 A MXPA03008186 A MX PA03008186A
- Authority
- MX
- Mexico
- Prior art keywords
- thrombotic
- medicaments
- production
- carboxylic acid
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10111842A DE10111842A1 (en) | 2001-03-13 | 2001-03-13 | Antithrombotic carboxylic acid amides, their preparation and their use as pharmaceuticals |
PCT/EP2002/002615 WO2002072558A1 (en) | 2001-03-13 | 2002-03-09 | Anti-thrombotic carboxylic acid amides, the production thereof and use of the same as medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03008186A true MXPA03008186A (en) | 2004-01-29 |
Family
ID=7677159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03008186A MXPA03008186A (en) | 2001-03-13 | 2002-03-09 | Anti-thrombotic carboxylic acid amides, the production thereof and use of the same as medicaments. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1370540A1 (en) |
JP (1) | JP2004529905A (en) |
CA (1) | CA2439231A1 (en) |
DE (1) | DE10111842A1 (en) |
MX (1) | MXPA03008186A (en) |
UY (1) | UY27202A1 (en) |
WO (1) | WO2002072558A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20040804A1 (en) | 2002-12-19 | 2004-12-31 | Boehringer Ingelheim Pharma | CARBOXAMID DERIVATIVES AS INHIBITORS OF THE Xa FACTOR |
KR101036391B1 (en) * | 2003-03-13 | 2011-05-23 | 이데미쓰 고산 가부시키가이샤 | Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same |
BRPI0414541B8 (en) | 2003-09-17 | 2021-05-25 | Janssen Pharmaceutica Nv | fused heterocyclic compounds having serotonin receptor modulating activity, method of preparing intermediate compounds |
US7371743B2 (en) | 2004-02-28 | 2008-05-13 | Boehringer Ingelheim International Gmbh | Carboxylic acid amides, the preparation thereof and their use as medicaments |
DE102004027821A1 (en) * | 2004-06-08 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Benzimidazoles, process for their preparation and their use as medicaments |
RU2007112688A (en) * | 2004-09-06 | 2008-10-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | 4-AMINOMETHYLBENZAMINE DERIVATIVES AND THEIR APPLICATION AS INHIBITORS OF FACTOR VIIA |
EP1928461B1 (en) * | 2005-08-04 | 2012-01-04 | Janssen Pharmaceutica NV | Pyrimidine compounds as serotonin receptor modulators |
US7598255B2 (en) | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
TW201444798A (en) | 2013-02-28 | 2014-12-01 | 必治妥美雅史谷比公司 | Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors |
US9828345B2 (en) | 2013-02-28 | 2017-11-28 | Bristol-Myers Squibb Company | Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors |
WO2020153414A1 (en) | 2019-01-24 | 2020-07-30 | 武田薬品工業株式会社 | Heterocyclic compound and use thereof |
JP2021050161A (en) | 2019-09-25 | 2021-04-01 | 武田薬品工業株式会社 | Heterocyclic compound and use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1078917A4 (en) * | 1998-02-17 | 2002-11-06 | Ono Pharmaceutical Co | Amidino derivatives and drugs containing the same as the active ingredient |
DE19912690A1 (en) * | 1999-03-20 | 2000-09-21 | Boehringer Ingelheim Pharma | New benzimidazolyl amidine or nitrile compounds, useful as thrombin inhibitors or antithrombotic agents, for treating deep leg vein thrombosis |
DE19929787A1 (en) * | 1999-06-29 | 2001-01-04 | Bayer Ag | New 4- (2-oxodihydrooxadiazinylphenyl) amides and their use |
DE19937494A1 (en) * | 1999-08-07 | 2001-02-08 | Boehringer Ingelheim Pharma | New carboxylic acid amides are Factor Xa and serine protease inhibitors, useful for the treatment and prevention of thrombotic disorders, tumors and fibrin-dependent inflammation |
-
2001
- 2001-03-13 DE DE10111842A patent/DE10111842A1/en not_active Withdrawn
-
2002
- 2002-03-09 CA CA002439231A patent/CA2439231A1/en not_active Abandoned
- 2002-03-09 MX MXPA03008186A patent/MXPA03008186A/en not_active Application Discontinuation
- 2002-03-09 EP EP02732472A patent/EP1370540A1/en not_active Withdrawn
- 2002-03-09 JP JP2002571474A patent/JP2004529905A/en active Pending
- 2002-03-09 WO PCT/EP2002/002615 patent/WO2002072558A1/en not_active Application Discontinuation
- 2002-03-11 UY UY27202A patent/UY27202A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1370540A1 (en) | 2003-12-17 |
CA2439231A1 (en) | 2002-09-19 |
UY27202A1 (en) | 2002-10-31 |
DE10111842A1 (en) | 2002-09-19 |
WO2002072558A1 (en) | 2002-09-19 |
JP2004529905A (en) | 2004-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |