MXPA03004334A - Receptor novedoso acoplado a proteina g humana, hgprbmy11, expresado altamente en corazon y variantes del mismo. - Google Patents
Receptor novedoso acoplado a proteina g humana, hgprbmy11, expresado altamente en corazon y variantes del mismo.Info
- Publication number
- MXPA03004334A MXPA03004334A MXPA03004334A MXPA03004334A MXPA03004334A MX PA03004334 A MXPA03004334 A MX PA03004334A MX PA03004334 A MXPA03004334 A MX PA03004334A MX PA03004334 A MXPA03004334 A MX PA03004334A MX PA03004334 A MXPA03004334 A MX PA03004334A
- Authority
- MX
- Mexico
- Prior art keywords
- hgprbmy11
- polypeptides
- variants
- heart
- human
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4719—G-proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La presente invencion proporciona polinucleotidos novedosos que codifican a los polipeptidos HGPRBMY11, fragmentos, y homologos de los mismos. La presente invencion tambien proporciona polinucleotidos que codifican variantes del polipeptido HGPRBMY11, HGPRBMY11v1 y HGPRBMY11v2. Tambien se proporcionan vectores, celulas hospedadoras, anticuerpos y metodos sinteticos y recombinantes para producir los polipeptidos. La invencion se refiere ademas a metodos terapeuticos y de diagnostico para aplicar estos polipeptidos novedosos HGPRBMY11, HGPRBMY11v1, y/o HGPRBMY11v2 al diagnostico, tratamiento, y/o prevencion de diversas enfermedades y/o trastornos relacionados con estos polipeptidos, particularmente enfermedades y/o trastornos cardiovasculares. La invencion se refiere ademas a metodos de separacion por exclusion para identificar agonistas y antagonistas de los polinucleotidos y polipeptidos de la presente invencion.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24961300P | 2000-11-17 | 2000-11-17 | |
US25761100P | 2000-12-21 | 2000-12-21 | |
US30581801P | 2001-07-16 | 2001-07-16 | |
PCT/US2001/044019 WO2002086123A2 (en) | 2000-11-17 | 2001-11-16 | A human g-protein coupled receptor, hgprbmy11, expressed highly in heart and variants thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03004334A true MXPA03004334A (es) | 2004-05-04 |
Family
ID=27400227
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03004334A MXPA03004334A (es) | 2000-11-17 | 2001-11-16 | Receptor novedoso acoplado a proteina g humana, hgprbmy11, expresado altamente en corazon y variantes del mismo. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20030153063A1 (es) |
EP (1) | EP1349928A2 (es) |
JP (1) | JP2005504510A (es) |
CA (1) | CA2429351A1 (es) |
IL (1) | IL155569A0 (es) |
MX (1) | MXPA03004334A (es) |
WO (1) | WO2002086123A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220002357A1 (en) * | 2018-12-04 | 2022-01-06 | The University Of North Carolina At Chapel Hill | G protein-coupled receptor screening systems |
CN113999873B (zh) * | 2021-12-31 | 2022-05-20 | 北京市疾病预防控制中心 | 一种基因修饰的非人动物的构建方法及其应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999005274A1 (en) * | 1997-07-23 | 1999-02-04 | Smithkline Beecham Corporation | Method of identifying novel g-protein receptors and their functions |
-
2001
- 2001-11-16 US US09/991,225 patent/US20030153063A1/en not_active Abandoned
- 2001-11-16 JP JP2002583637A patent/JP2005504510A/ja active Pending
- 2001-11-16 IL IL15556901A patent/IL155569A0/xx unknown
- 2001-11-16 MX MXPA03004334A patent/MXPA03004334A/es not_active Application Discontinuation
- 2001-11-16 WO PCT/US2001/044019 patent/WO2002086123A2/en not_active Application Discontinuation
- 2001-11-16 EP EP01273748A patent/EP1349928A2/en not_active Withdrawn
- 2001-11-16 CA CA002429351A patent/CA2429351A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1349928A2 (en) | 2003-10-08 |
JP2005504510A (ja) | 2005-02-17 |
WO2002086123A2 (en) | 2002-10-31 |
IL155569A0 (en) | 2003-11-23 |
US20030153063A1 (en) | 2003-08-14 |
CA2429351A1 (en) | 2002-10-31 |
WO2002086123A3 (en) | 2003-07-31 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |