MXPA03001468A - Polipeptidos de claudia. - Google Patents

Polipeptidos de claudia.

Info

Publication number
MXPA03001468A
MXPA03001468A MXPA03001468A MXPA03001468A MXPA03001468A MX PA03001468 A MXPA03001468 A MX PA03001468A MX PA03001468 A MXPA03001468 A MX PA03001468A MX PA03001468 A MXPA03001468 A MX PA03001468A MX PA03001468 A MXPA03001468 A MX PA03001468A
Authority
MX
Mexico
Prior art keywords
claudin
methods
claudin polypeptides
polypeptides
treat
Prior art date
Application number
MXPA03001468A
Other languages
English (en)
Inventor
Adel Youakim
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of MXPA03001468A publication Critical patent/MXPA03001468A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Esta invencion se refiere a nuevos miembros de la familia de polipeptido de Claudina de humano, a metodos para elaborar tales polipeptidos, y a metodos para utilizarse en el tratamiento de condiciones asociadas con Claudina y para identificar compuestos que alteran las actividades del polipeptido de Claudina.
MXPA03001468A 2000-08-15 2001-08-15 Polipeptidos de claudia. MXPA03001468A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22551300P 2000-08-15 2000-08-15
US22579400P 2000-08-15 2000-08-15
PCT/US2001/025662 WO2002014499A2 (en) 2000-08-15 2001-08-15 Claudin polypeptides

Publications (1)

Publication Number Publication Date
MXPA03001468A true MXPA03001468A (es) 2004-05-04

Family

ID=26919667

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03001468A MXPA03001468A (es) 2000-08-15 2001-08-15 Polipeptidos de claudia.

Country Status (10)

Country Link
US (1) US20080254506A1 (es)
EP (1) EP1311663B1 (es)
JP (1) JP2004519215A (es)
AT (1) ATE363531T1 (es)
AU (2) AU2001284977B2 (es)
CA (1) CA2418725A1 (es)
DE (1) DE60128701T2 (es)
ES (1) ES2284678T3 (es)
MX (1) MXPA03001468A (es)
WO (1) WO2002014499A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833839A1 (fr) * 2001-12-21 2003-06-27 Rytek Methodes et compositions pour le traitement de pathologies respiratoires
FR2833840B1 (fr) * 2001-12-21 2010-06-18 Rytek Methodes et compositions pour le traitement de pathologies respiratoires
US7452877B2 (en) 2002-03-15 2008-11-18 Rytek Methods for treating digestive functional pathologies
FR2837103B1 (fr) * 2002-03-15 2004-07-09 Rytek Compositions pour le traitement de pathologies fonctionelles digestives
FR2844201A1 (fr) * 2002-09-06 2004-03-12 Rytek Compositions pour le traitement de pathologies fonctionnelles digestives
EP1509540A4 (en) 2002-05-20 2005-10-26 Immunex Corp CLAUDIN POLYPEPTIDES, POLYNUCLEOTIDES AND METHODS OF MAKING AND USING SAME
FR2844713A1 (fr) * 2002-09-25 2004-03-26 Exonhit Therapeutics Sa Nouvelle cible de l'angiogenese et utilisations
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE102004023187A1 (de) * 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
FR2879100B1 (fr) 2004-12-09 2007-07-06 Lionel Bueno Compositions pour le traitement des pathologies oculaires de surface et de la retine
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
CA2702180A1 (en) 2007-10-12 2009-04-16 Peter Humphries Method for opening tight junctions
JP5234666B2 (ja) * 2009-12-11 2013-07-10 国立大学法人大阪大学 乾癬の判定のための測定方法
WO2013174404A1 (en) 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
RU2678127C2 (ru) 2012-11-13 2019-01-23 Бионтех Аг Агенты для лечения экспрессирующих клаудин раковых заболеваний
WO2014127785A1 (en) 2013-02-20 2014-08-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014146672A1 (en) 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2016138245A2 (en) 2015-02-27 2016-09-01 The Regents Of The University Of Michigan Claudin-1 peptide reagents and methods
US10738079B2 (en) 2017-04-14 2020-08-11 Emory University Compositions and methods for managing respiratory conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2299226A1 (en) * 1997-08-06 1999-02-18 Millennium Biotherapeutics, Inc. Tango-71, tango-73, tango-74, tango-76, and tango-83 nucleic acid molecules and polypeptides
AU766279B2 (en) * 1998-10-06 2003-10-16 Curagen Corporation Novel secreted proteins and polynucleotides encoding them
EP1127119A1 (en) * 1998-11-03 2001-08-29 Adherex Technologies, Inc. Compounds and methods for modulating claudin-mediated functions
US20040033493A1 (en) * 2001-01-31 2004-02-19 Tchernev Velizar T. Proteins and nucleic acids encoding same

Also Published As

Publication number Publication date
EP1311663A2 (en) 2003-05-21
DE60128701D1 (en) 2007-07-12
CA2418725A1 (en) 2002-02-21
US20080254506A1 (en) 2008-10-16
DE60128701T2 (de) 2008-02-07
WO2002014499A2 (en) 2002-02-21
EP1311663B1 (en) 2007-05-30
ATE363531T1 (de) 2007-06-15
WO2002014499A9 (en) 2002-04-18
WO2002014499A3 (en) 2002-10-31
JP2004519215A (ja) 2004-07-02
ES2284678T3 (es) 2007-11-16
AU2001284977B2 (en) 2005-11-24
AU8497701A (en) 2002-02-25

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Legal Events

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