MXPA03000914A - Sintesis de (r)-3-(4 -bromobencil) -1-(3, 5-diclorofenil) -5-yodo-3 -metil-1-h -imidazo[1, 2-a]imidazol -2-ona. - Google Patents
Sintesis de (r)-3-(4 -bromobencil) -1-(3, 5-diclorofenil) -5-yodo-3 -metil-1-h -imidazo[1, 2-a]imidazol -2-ona.Info
- Publication number
- MXPA03000914A MXPA03000914A MXPA03000914A MXPA03000914A MXPA03000914A MX PA03000914 A MXPA03000914 A MX PA03000914A MX PA03000914 A MXPA03000914 A MX PA03000914A MX PA03000914 A MXPA03000914 A MX PA03000914A MX PA03000914 A MXPA03000914 A MX PA03000914A
- Authority
- MX
- Mexico
- Prior art keywords
- synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22416600P | 2000-08-09 | 2000-08-09 | |
PCT/US2001/023996 WO2002012243A2 (en) | 2000-08-09 | 2001-07-31 | SYNTHESIS OF (R)-3-(4-BROMOBENZYL)-1-(3,5-DICHLOROPHENYL)-5-IODO-3-METHYL-1-H-IMIDAZO[1,2-a]IMIDAZOL-2-ONE |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03000914A true MXPA03000914A (es) | 2003-10-06 |
Family
ID=22839546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03000914A MXPA03000914A (es) | 2000-08-09 | 2001-07-31 | Sintesis de (r)-3-(4 -bromobencil) -1-(3, 5-diclorofenil) -5-yodo-3 -metil-1-h -imidazo[1, 2-a]imidazol -2-ona. |
Country Status (6)
Country | Link |
---|---|
US (5) | US6414161B1 (es) |
EP (1) | EP1309595A2 (es) |
JP (1) | JP2004505978A (es) |
CA (1) | CA2416906A1 (es) |
MX (1) | MXPA03000914A (es) |
WO (1) | WO2002012243A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2434558A1 (en) * | 2001-01-26 | 2002-08-01 | Dmitry Zuev | Imidazolyl derivatives as corticotropin releasing factor inhibitors |
US6844360B2 (en) * | 2002-10-30 | 2005-01-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide |
US7700603B2 (en) | 2003-12-15 | 2010-04-20 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
US7592348B2 (en) | 2003-12-15 | 2009-09-22 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
BRPI0513807A (pt) * | 2004-07-27 | 2008-05-13 | Boehringer Ingelheim Pharma | sìntese de amidas do ácido 6, 7 - diidro - 5h - imidazo [1, 2-a] imidazol - 3 - sulfÈnico |
US7091231B2 (en) * | 2004-12-10 | 2006-08-15 | Allergan, Inc. | 12-Aryl prostaglandin analogs |
TW201004961A (en) | 2005-06-14 | 2010-02-01 | Schering Corp | Aspartyl protease inhibitors |
CA2636455A1 (en) * | 2006-01-20 | 2007-07-26 | Boehringer Ingelheim International Gmbh | Process for the preparation of 6,7-dihydro-5h-imidazo[1,2-a]imidazole-3-sulfonic acid amides and intermediates used therein |
US20070244737A1 (en) * | 2006-04-13 | 2007-10-18 | Melvin Herrin | Automatic golf player matching and scheduling system |
US8168641B2 (en) | 2006-06-12 | 2012-05-01 | Schering Corporation | Aspartyl protease inhibitors |
EP2064191B1 (en) | 2006-12-12 | 2014-06-25 | Merck Sharp & Dohme Corp. | Aspartyl protease inhibitors |
JP5384733B2 (ja) | 2009-06-02 | 2014-01-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 6,7−ジヒドロ−5H−イミダゾ[1,2−a]イミダゾール−3−カルボン酸アミドの誘導体 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2827617A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Sohn Ingelheim | Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
JPS55124763A (en) * | 1979-03-19 | 1980-09-26 | Ishihara Sangyo Kaisha Ltd | 5-trifluoromethyl-2-pyridone derivative |
US5484802A (en) * | 1995-03-29 | 1996-01-16 | Patel; Bomi P. | Fungicidal α-(dioxoimidazolidine)acetanilide compounds |
NZ337698A (en) * | 1997-04-04 | 2001-07-27 | Pfizer Prod Inc | Nicotinamide derivatives for selective inhibition of phosphodiesterase type 4 (PDE4) and the production of tumour necrosis factor (TNF) useful for the treatment of respiratory, rheumatoid and allergic diseases |
UY25842A1 (es) * | 1998-12-16 | 2001-04-30 | Smithkline Beecham Corp | Antagonistas de receptores de il-8 |
US6492408B1 (en) * | 1999-07-21 | 2002-12-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammatory disease |
US6525046B1 (en) * | 2000-01-18 | 2003-02-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Aromatic heterocyclic compounds as antiinflammatory agents |
-
2001
- 2001-07-31 WO PCT/US2001/023996 patent/WO2002012243A2/en active Application Filing
- 2001-07-31 JP JP2002518218A patent/JP2004505978A/ja active Pending
- 2001-07-31 US US09/918,915 patent/US6414161B1/en not_active Expired - Lifetime
- 2001-07-31 EP EP01957358A patent/EP1309595A2/en not_active Withdrawn
- 2001-07-31 CA CA002416906A patent/CA2416906A1/en not_active Abandoned
- 2001-07-31 MX MXPA03000914A patent/MXPA03000914A/es active IP Right Grant
-
2002
- 2002-02-15 US US10/077,043 patent/US6437148B1/en not_active Expired - Lifetime
- 2002-02-15 US US10/077,044 patent/US6458986B1/en not_active Expired - Lifetime
- 2002-02-15 US US10/077,045 patent/US6441183B1/en not_active Expired - Lifetime
- 2002-02-15 US US10/076,829 patent/US6433183B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2416906A1 (en) | 2002-02-14 |
US6437148B1 (en) | 2002-08-20 |
US20020082441A1 (en) | 2002-06-27 |
JP2004505978A (ja) | 2004-02-26 |
US6433183B1 (en) | 2002-08-13 |
US6414161B1 (en) | 2002-07-02 |
US20020028949A1 (en) | 2002-03-07 |
US20020072615A1 (en) | 2002-06-13 |
WO2002012243A3 (en) | 2002-06-20 |
US20020072610A1 (en) | 2002-06-13 |
WO2002012243A2 (en) | 2002-02-14 |
US20020087009A1 (en) | 2002-07-04 |
US6458986B1 (en) | 2002-10-01 |
EP1309595A2 (en) | 2003-05-14 |
US6441183B1 (en) | 2002-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |