MXPA02006617A - Dihidrobenzopiranos, dihidrobenzotiopiranos, y tetrahidroquinolinas para el tratamiento de desordenes mediados por cox-2. - Google Patents

Dihidrobenzopiranos, dihidrobenzotiopiranos, y tetrahidroquinolinas para el tratamiento de desordenes mediados por cox-2.

Info

Publication number
MXPA02006617A
MXPA02006617A MXPA02006617A MXPA02006617A MXPA02006617A MX PA02006617 A MXPA02006617 A MX PA02006617A MX PA02006617 A MXPA02006617 A MX PA02006617A MX PA02006617 A MXPA02006617 A MX PA02006617A MX PA02006617 A MXPA02006617 A MX PA02006617A
Authority
MX
Mexico
Prior art keywords
dihydrobenzothiopyrans
dihydrobenzopyrans
tetrahydroquinolines
disorders
treatment
Prior art date
Application number
MXPA02006617A
Other languages
English (en)
Inventor
Donald J Rogier Jr
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22635573&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA02006617(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MXPA02006617A publication Critical patent/MXPA02006617A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Abstract

Se describe una clase de dihidrobenzopiranos, dihidrobenzotiopiranos, tetrahidroquinolinas, tetrahidronaftalenos, y analogos de los mismos, para el uso en el tratamiento de desordenes mediados por la ciclooxigenasa-2. Los compuestos de interes particular son definidos por la formula (I) en donde X, A1, A2, A3, A4, R , R????, R1 y R2 son como se describen en la especificacion.
MXPA02006617A 2000-01-03 2000-12-19 Dihidrobenzopiranos, dihidrobenzotiopiranos, y tetrahidroquinolinas para el tratamiento de desordenes mediados por cox-2. MXPA02006617A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17428100P 2000-01-03 2000-01-03
PCT/US2000/034525 WO2001049675A1 (en) 2000-01-03 2000-12-19 Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders

Publications (1)

Publication Number Publication Date
MXPA02006617A true MXPA02006617A (es) 2004-09-10

Family

ID=22635573

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02006617A MXPA02006617A (es) 2000-01-03 2000-12-19 Dihidrobenzopiranos, dihidrobenzotiopiranos, y tetrahidroquinolinas para el tratamiento de desordenes mediados por cox-2.

Country Status (16)

Country Link
US (2) US6822102B2 (es)
EP (1) EP1274700B1 (es)
JP (1) JP2003519221A (es)
AR (1) AR026784A1 (es)
AT (1) ATE282604T1 (es)
AU (1) AU2584001A (es)
CA (1) CA2395795A1 (es)
DE (1) DE60016047T2 (es)
EC (1) ECSP013867A (es)
ES (1) ES2231301T3 (es)
MX (1) MXPA02006617A (es)
PE (1) PE20010995A1 (es)
PT (1) PT1274700E (es)
TW (1) TWI227234B (es)
WO (1) WO2001049675A1 (es)
ZA (1) ZA200205098B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100594A1 (en) * 2001-08-10 2003-05-29 Pharmacia Corporation Carbonic anhydrase inhibitor
AU2003277285B2 (en) 2002-10-04 2007-12-13 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7504508B2 (en) 2002-10-04 2009-03-17 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
CA2424009A1 (en) 2003-03-28 2004-09-28 Ibm Canada Limited - Ibm Canada Limitee Context-sensitive attributes
GB0407908D0 (en) * 2004-04-07 2004-05-12 Univ York Ionic liquids
TW200603792A (en) * 2004-04-23 2006-02-01 Pharmacia & Upjohn Co Llc Monotherapy for the treatment of psoriasis with cyclooxygenase-2 selective inhibitors
US7122700B2 (en) 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
WO2006040672A1 (en) * 2004-10-12 2006-04-20 Pharmacia & Upjohn Company Llc Substituted cyclopropyl chromene compounds for use in the treatment and prevention of inflammation related conditions
KR20070114762A (ko) 2005-02-24 2007-12-04 밀레니엄 파머슈티컬스 인코퍼레이티드 염증 질환 치료를 위한 ｐｇｄ2 수용체 길항제
US7999107B2 (en) 2007-01-31 2011-08-16 Merck Sharp & Dohme Corp. Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
MX2013000537A (es) 2010-07-14 2013-01-29 Novartis Ag Compuestos heterociclicos agonistas del receptor ip.
EP2802589B1 (en) 2012-01-13 2016-01-06 Novartis AG Fused pyrroles as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100343832B1 (ko) * 1996-08-27 2002-07-20 시오노기세이야쿠가부시키가이샤 크로멘-3-카르복실산 유도체
DE19638484A1 (de) * 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation

Also Published As

Publication number Publication date
US20050010050A1 (en) 2005-01-13
PT1274700E (pt) 2005-02-28
JP2003519221A (ja) 2003-06-17
DE60016047T2 (de) 2005-11-03
EP1274700B1 (en) 2004-11-17
ATE282604T1 (de) 2004-12-15
ZA200205098B (en) 2004-03-31
DE60016047D1 (de) 2004-12-23
EP1274700A1 (en) 2003-01-15
PE20010995A1 (es) 2001-09-21
ES2231301T3 (es) 2005-05-16
CA2395795A1 (en) 2001-07-12
US6822102B2 (en) 2004-11-23
US20030232844A1 (en) 2003-12-18
WO2001049675A1 (en) 2001-07-12
ECSP013867A (es) 2002-09-27
AR026784A1 (es) 2003-02-26
AU2584001A (en) 2001-07-16
TWI227234B (en) 2005-02-01

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