MXPA01010760A - Wet wipes having skin health benefits - Google Patents
Wet wipes having skin health benefitsInfo
- Publication number
- MXPA01010760A MXPA01010760A MXPA/A/2001/010760A MXPA01010760A MXPA01010760A MX PA01010760 A MXPA01010760 A MX PA01010760A MX PA01010760 A MXPA01010760 A MX PA01010760A MX PA01010760 A MXPA01010760 A MX PA01010760A
- Authority
- MX
- Mexico
- Prior art keywords
- weight
- oil
- clause
- composition
- peg
- Prior art date
Links
- 230000036559 skin health Effects 0.000 title abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 138
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- 235000003702 sterols Nutrition 0.000 claims abstract description 67
- 150000003432 sterols Chemical class 0.000 claims abstract description 57
- 239000007764 o/w emulsion Substances 0.000 claims abstract description 33
- 239000004094 surface-active agent Substances 0.000 claims abstract description 33
- 235000019197 fats Nutrition 0.000 claims abstract description 30
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- 240000001624 Espostoa lanata Species 0.000 claims abstract description 4
- 230000001058 adult Effects 0.000 claims abstract description 4
- 238000004140 cleaning Methods 0.000 claims description 130
- 239000004744 fabric Substances 0.000 claims description 114
- 239000003921 oil Substances 0.000 claims description 107
- 210000003491 Skin Anatomy 0.000 claims description 99
- -1 cholesterol sterols Chemical class 0.000 claims description 70
- 239000010410 layer Substances 0.000 claims description 47
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 40
- 239000000463 material Substances 0.000 claims description 32
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- 239000004359 castor oil Substances 0.000 claims description 28
- 235000019438 castor oil Nutrition 0.000 claims description 28
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Chemical group CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 26
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- 239000004166 Lanolin Substances 0.000 claims description 25
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 16
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical group OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 16
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- PJHKBYALYHRYSK-UHFFFAOYSA-N triheptanoin Chemical compound CCCCCCC(=O)OCC(OC(=O)CCCCCC)COC(=O)CCCCCC PJHKBYALYHRYSK-UHFFFAOYSA-N 0.000 description 1
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Abstract
A skin health enhancing soft wet wipe or wipe-type product, such as a baby wipe, an adult wipe, hand wipe, a face wipe, a cosmetic wipe, a household wipe, an industrial wipe, a personal cleansing wipe, cotton balls, cotton tipped swabs, and the like, can be made by combining the wipe or wipe-type product with an oil-in-water emulsion composition comprising a natural fat or oil, sterol or sterol derivative, humectant, emulsifying surfactant, and water.
Description
WET CLEANING CLOTHES HAVING SKIN HEALTH BENEFITS
Field of the Invention
The present invention relates to wet cleaning cloths and cleaning cloth type products. More particularly, the present invention relates particularly to wet cleaning cloths and cleaning cloth-type products that can be used for a variety of purposes including cleaning, cosmetics removal, and sanitation comprising an emulsion composition solution of Oil in water that cleanses the surface of the skin and provides increased skin health benefits.
Background of the Invention
The stratum corneum is the outermost layer of the skin and is responsible for the regulation of water levels in the skin and works as a barrier against chemicals and other stressors found in the environment. The complex arrangement of lipids in the space between the cells of the stratum corneum is responsible for the establishment of a normal barrier function. The multi-layered structures of cholesterol, ceramides, and fatty acids, as well as some other minor lipids, provide the main barrier to the transport of hydrophilic substances in or through the skin. The link between barrier function and skin health can be seen through the inflammation of the skin that results from the extraction of lipids from the skin.
In addition to the information, the interrupted barrier function can result in a number of skin conditions, most notably, dry skin. Humidifiers that consist of humectants or occlusive chemicals are commonly used to treat dry skin.
Diaper dermatitis, in infants and adults, is a genre of skin conditions that, in large part, originates from a damaged barrier function. Skin barrier damage can result from a variety of factors, including: Increased skin hydration due to skin occlusion caused by diapers, enzymatic skin damage due to fecal and urinary enzymes, physical abrasion caused by diapers, wash cloths, and wet cleaning cloths, and the removal of lipids from the skin by a surfactant associated with bathing and cleaning.
Occlusion of the skin results in increased hydration of the skin due to blockage of evaporative water lost from the surface of the skin. The level of hydration of the skin wrapped in diapers can reach between five to ten times that of a skin without diapers. Frequent skin contact with diapers with urine can also help increase skin hydration. Increased skin hydration disrupts the organization of skin lipids in the stratum corneum. This interruption may increase the permeability of the skin allowing the penetration of irritants from the stool and urine inside the skin.
The results of the studies carried out on hairless mice reveal that fecal enzymes, specifically proteases and lipases, are the main irritants of the skin in a skin environment with diapers. Faecal proteases degrade stratum corneum proteins resulting in inflammatory reactions and in facilitating the penetration of low molecular weight irritants. It was observed that urine raises the pH of the skin thus facilitating the enzymatic action on the skin as well as causing inflammatory reactions in the skin.
The skin with diapers is typically cleaned by the application of cotton wash cloth or by means of disposable wet wipes. The effect on the skin of the wet cleaning cloths depends on the materials and the surfactant systems used for the cleaning cloths. The skin with diapers is usually cleaned several times a day with cleaning cloths using solutions containing surfactants. Surfactants are known to remove lipids from the stratum corneum or disrupt the lipid structure within the stratum corneum, thus decreasing the barrier function. The cleaning cloth and the cleaning cloth type product material can cause damage by physical abrasion to the skin and can lead to an increase in the transpidermal water loss, an indication of the diminished barrier function. Other cases from which the breakdown of skin barrier function results are frequent hand washing and contact dermatitis that originates from harsh surfactants and other chemical irritants.
Once the skin barrier has been compromised, a series of events can occur within the skin to synthesize and organize the lipids to restore the function of the barrier. The body naturally repairs defects in the function of the skin barrier by increasing the production of key lipids found in the skin, such as cholesterol, ceramides, and fatty acids, and key lipid synthesizing enzymes. Two known environmental conditions inhibit the natural skin barrier repair mechanisms in relation to a skin wrapped in diapers. The first condition is a pH of neutral skin, and the other condition is the occlusion of the skin. Chronic exposure to faeces and urine, as well as continued occlusion of the skin, therefore leads to the chronic interruption of the skin's barrier function.
Wet cleaning cloths are well-known commercial consumer products that have been available in many forms. Perhaps the most common form of wet cleaning cloths has been a moistened pile of leaves that have been packed in a plastic container. Wet cleaning wipes have been made from a variety of materials that have been moistened with a variety of mild and suitable surfactant based solutions. Such wet cleaning cloths have been used for baby wipes, hand wipes, household wipes, industrial wipes, body wipes and face wipes, and the like.
Typically, such conventional cleaning cloths have included a single layer of an essentially homogeneous material. For example, conventional wet wiping cloths have included a fabric of air-laid fibers that are mixed or evenly distributed throughout the fabric. Wipers have included polymeric fibers such as polyester, polyethylene and polypropylene and natural or synthetic fibers such as cellulosic fibers. Other conventional wet wiping cloths have included a woven fabric of polypropylene and cellulosic fibers wherein the fibers are uniformly mixed through the fabric.
However, other forms of the wet cleaning cloth or cleaning cloth type products include a cleaning cloth product having a nonwoven layered base sheet. The layered base sheet may include at least two layers placed in a front relationship with one another, wherein one of the layers includes fibers that are not included in the other layer. Such an arrangement can be where at least one of the layers includes polyethylene fibers and at least one of the layers includes polypropylene fibers. In alternate forms, the layers may include similar materials, but in different amounts. The different layers may be configured to provide different physical properties, such as the softness for the cleaning cloth product while another layer may be configured to provide other properties, such as strength, to the cleaning cloth product.
The balance of physical properties, such as softness, flexibility, strength, integrity and elasticity has not been fully optimized. The topical chemistry can be used to increase the properties of the delivered product of the wet cleaning cloths of the cleaning cloth type products. This has been particularly true for those users who want improved skin health or the ability to impart health benefits to the skin. The skin health benefits of the cleansing cloth product or the skin health benefits imparted by the cleansing cloth product may be perceived as being particularly important for cleansing wipes for the body which are intended for repeated contact with the skin. the skin of an adult to an infant.
Therefore, what is required in the art are products that help to maintain the skin's barrier function, particularly in the skin environment with diapers, such as a wet cleaning cloth product or cleaning cloth type that: a) deposit adequate chemicals on the skin to increase the skin barrier; b) minimize physical damage to the skin due to the cleaning cloth; c) leave the feeling of soft and docile skin; and d) provide a long-lasting benefit until the next cleaning event while effective cleansing is still provided while providing an increase in skin barrier.
Synthesis of the Invention
It has now been discovered that an improved cleaning cloth or wiper cloth product, used for a variety of purposes, including cleaning, cosmetics removal and sanitation, that increases the skin barrier can be made by applying, absorbing inside. or otherwise moistening the wet cleaning cloth or the cleaning cloth type product with an oil-in-water emulsion composition comprising a natural fat or oil, sterol or a sterol derivative, a humectant, emulsifying surfactants and surfactant combinations that They have a range of hydrophilic and lipophilic balance of around 7 to about 18 and water. The composition is also easily transferred from the wet cleansing diaper or from the cleansing cloth type sheet to the skin being contacted with the sheet to provide increased skin barrier benefits while providing a desired product purpose. .
Therefore, in one aspect, the invention relates to an oil-in-water emulsion composition comprising from about 0.1 percent by weight to about 30 percent by weight of natural fats or oils, from about 0.1. percent by weight to about 10 percent by weight of a sterol or a sterol derivative, from about 0.1 weight percent to about 99.5 weight percent of a humectant, and from about 0.5 to 0.5 weight percent; about 20 percent by weight of an emulsifying surfactant that has a range of hydrophilic and lipophilic balance of around to about 18, from about 45 to about 99.5 percent by weight of water and the pH of the adjusted emulsion at a pH of about 4 to about 7. The pH adjustments of the composition can be made using any acid or base known in the art. An example of an acid is malic acid. Optionally, the composition may contain from about 0 to about 30 percent by weight of petrolatum or mineral oil.
Detailed description of the invention
The present invention relates to wet cleaning cloths or cleaning cloth type products which have improved health benefits for the skin due to the oil-in-water emulsion composition. Wet cleaning cloths or wet cleaning cloth type products of the present invention can be used for baby wipes, adult wipes, hand wipes, face cleaning wipes, cosmetic wipes, wiping cloths household, industrial cleaning cloths, cleaning cloths for personal cleaning, cotton balls, and cotton-tipped scourers and the like.
An embodiment of the present invention is a wet cleaning bath or a cleaning cloth type product which improves the skin barrier and which has at least one layer and an oil-in-water emulsion composition. The composition of the oil-in-water emulsion may comprise from about 0.1 to about 30 weight percent of natural fats or oils, from about 0.1 to about 10 weight percent of sterol or sterol derivative , from from about 0.1 to about 30 percent by weight of humectant, from about 0.5 to about 20 percent by weight surfactant emulsifier having a hydrophilic and-lipophilic balance range of from about 7 to about of 18, and from about 45 to about 99.5 percent by weight of water.
The emulsion composition can have a pH ranging from about 4 to about 7. pH adjustments can be made using malic acid. The amount of the oil-in-water emulsion composition contained within each cleaning cloth or wiper-type product can vary from about 150 to about 600 percent by weight based on the product weight.
The water contained in the composition can be a mixture of water and alcohol. The preferred alcohols are ethanol, and isopropyl alcohol. The amount of alcohol in the water is up to about 70 percent by weight of the water and the alcohol solution. More preferably, the amount of alcohol in the water is from about 40 to about 60 percent by weight of the water and the alcohol solution.
The fat or natural oil used in the composition may include borage oil, avocado oil, or sunflower oil. The sterol or sterol derivative used in the composition may include soy sterol, avocado sterols or cholesterol. The humectant used in the composition may include glycerin, sorbitol, or propylene glycol. The emulsifying surfactant used in the composition may include glyceryl stearate SE, wax NF emulsifier, or propylene glycol oleate SE. The composition can further comprise from about 0.1 to about 30 percent by weight of petrolatum or mineral oil.
Another embodiment of the present invention is a method for making a cleaning cloth or cleaning cloth product comprising: (a) providing at least one single layer fabric of a nonwoven material; b) applying an oil-in-water emulsion composition comprising a fat or natural oil, a sterol or a sterol derivative, a humectant, and an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to about of 18, for non-woven material; c) cutting said fabric into individual sheets to provide products of a wet cleaning cloth or a cleaning cloth type. In some cases, the oil-in-water emulsion composition is absorbed into said product.
Another embodiment of the present invention is a nonwoven cleaning cloth type product that increases the skin barrier having an oil-in-water emulsion composition. The oil-in-water composition can comprise from about 0.1 to about 30 percent by weight of natural fats or oils, from about 0.1 to about 10 percent by weight of sterol or of a sterol derivative, of from about 0.1 to about 30 percent by weight of humectant, from about 0.5 to about 20 percent by weight of the emulsifying surfactant having a lipophilic hydrophilic balance range of from about 7 to about 18 and from from around 45 to about 99.5 percent by weight of water. The composition can have a pH ranging from about 4 to about 7. pH adjustments can be made using malic acid.
The water contained in the composition can be a mixture of water and alcohol. The preferred alcohols are ethanol and isopropyl alcohol. The amount of alcohol in the water is up to about 70 percent by weight of the water and the alcohol solution. More preferably, the amount of alcohol in the water is from about 40 to about 60 percent by weight of the water and the alcohol solution.
Another embodiment of the present invention is a method for making a nonwoven cleaning cloth type product comprising: (a) providing a nonwoven fabric;
(b) applying an oil-in-water emulsion composition comprising a fat or natural oil, a sterol or a sterol derivative, a humectant, and an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to around 18, to the non-woven material; (c) cutting said fabric into cleaning cloth type products of individual product size pieces or components for cleaning cloth type products. In some cases, the oil-in-water composition is absorbed in said product.
Another embodiment of the present invention is an oil-in-water emulsion composition comprising from about 0.1 to about 30 percent by weight of natural fats or oils, from about 0.1 to about 10 percent by weight of sterol or a sterol derivative, from about 0.1 to about 30 percent by weight of the humectant, from about 0.5 to about 40 percent by weight of the emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to about 18, and from about 45 about 99.5 percent by weight of water. The emulsion composition may also include from about 0 to about 30 percent by weight of petrolatum or mineral oil. The emulsion composition can have a pH ranging from about 4 to about 7. pH adjustments can be made using malic acid.
The water contained in the composition can be a mixture of water and alcohol. The preferred alcohols are ethanol and isopropyl alcohol. The amount of alcohol in the water up to about 70 percent by weight of the water and the alcohol solution. More preferably, the amount of alcohol in the water is from about 40 to about 60 percent of the water and the alcohol solution.
The natural fats or oils of the oil-in-water emulsion composition can be selected from the group consisting of avocado oil, apricot oil, babassu oil, borage oil, camellia oil, canola oil, castor oil, coconut oil, corn oil, cottonseed oil, evening primrose oil, hydrogenated cottonseed oil, hydrogenated palm kernel oil, beaten soy bean oil, prairie foam oil, oil palm kernel, phospholipids, rapeseed oil, palmitic acid, stearic acid, linoleic acid, stearyl alcohol, lauryl alcohol, myristyl alcohol, behenyl alcohol, rose hip oil, sunflower oil, soy bean oil, and mixtures of same. The amount of said fats or oils used in the composition can be from about 0.5 to about 10 percent by weight, and more preferably from about 1 to about 5 percent.
The sterol or sterol derivatives of the oil in water composition can be selected from the group consisting of cholesterol, cytosterol, stigmaterol, ergosterol, latherterol, soybean sterol, avocado sterols, cholesterol esters, sterol esters, avocadine, lanolin and mixtures thereof.
The amount of the emulsifying surfactants used in the oil-in-water emulsion composition may be more preferably from about 1 to about 15 weight percent. The amount of the humectant used in the emulsion composition can be more preferably from about 0.5 to about 20 percent by weight.
An incorporation of the composition comprises about 1 percent by weight of borage oil, about 0.8 percent by weight of soy sterol, about 5 percent glycerin, about 3 percent by weight of glyceryl stearate SE, and about 90.2 percent by weight of water. The emulsion composition can have a pH of about 5.5.
Another incorporation of the composition comprises about 1 percent by weight of borage oil, about 0.8 percent by weight of soy sterol, about 5 percent by weight of glycerin, about 3 percent by weight of glyceryl stearate SE, about 1 percent by weight of USP petrolatum, about 1 percent by weight of PROLIPID 141, and about 88.9 percent by weight of water. The emulsion composition may have a pH of about 5.5 (PROLIPID is commercially available from International Specialty Products, located in Wayne, New Jersey.) PROLIPID is generally described in United States Patent No. 5,849,315 issued to Rerek. , which was granted on December 15, 1998, which is incorporated herein by reference in which it is consistent with this.
Another embodiment of the composition comprises about 0.5 percent by weight of Avocadin, about 0.5 percent by weight of sterol esters, about 5 percent by weight of glycerin, about 1 percent by weight of glyceryl stearate in the form of PROLIPID 141, and about 92 percent by weight of water. The composition of the emulsion may have a pH of about 5.5.
Another embodiment of the composition comprises about 10 percent by weight of sunflower oil, about 1 percent by weight of cholesterol, about 3 percent by weight of glycerin, about 5 percent by weight of NF emulsifying wax, and about 81 percent by weight of water. The emulsion composition can have a pH of about 5.5.
Another incorporation of the composition comprises about 5 percent by weight of avocado oil, about 1 percent by weight of latherterol, about 1 percent by weight of sorbitol, about 5 percent by weight of propylene glycol oleate SE, and about 88 percent by weight of water. The emulsion composition can have a pH of about 5.5.
Another incorporation of the composition comprises about 10 percent by weight of palm kernel oil, about 1 percent by weight of latherterol, about 15 percent by weight of hydrogenated starch hydrolyzate, of about 15 percent by weight. weight of glyceryl stearate, about 5 percent by weight of petrolatum or mineral oil, and about 54 percent by weight of water. The emulsion composition can have a pH of about 5.5.
Another embodiment of the composition comprises about 10 weight percent lanolin, about 5 weight percent soy sterol, about 5 weight percent glycerin, about 10 weight percent NF emulsifying wax, about 5 percent by weight of petrolatum or mineral oil, and about 60 percent by weight of water. The composition can have a pH of about 5.5.
Another embodiment of the composition comprises about 15 percent by weight of cottonseed oil, about 15 percent by weight of sterol esters, about 10 percent by weight of propylene glycol, about 15 percent by weight of propylene glycol oleate SE, about 10 percent by weight of petrolatum or mineral oil and about 45 percent by weight of water. The composition of the emulsion may have a pH of about 5.5.
Another incorporation of the composition comprises about 30 weight percent afternoon primrose oil, about 5 weight percent cholesterol, about 5 weight percent sodium PCA, about 10 weight percent weight. propylene glycol oleate SE, and about 50 percent by weight of water. The emulsion composition can have a pH of about 5.5.
The amount of a natural oil or fat or a mixture of natural oils or fats in the composition of the oil in water emulsion can be from about 0.1 weight percent to about 30 weight percent, more specifically from from about 0.5 percent by weight to about 10 percent by weight, more specifically from about 1 percent by weight to about 5 percent by weight. As used herein, the phrase "natural fats or oils" is understood as including fats, oils, essential oils, fatty acids and mixtures thereof. As used herein, natural fats or oils include, but are not limited to, the following materials classified according to the CTFA designations:
Fats and Oils: Peach Nut Oil, Avocado Oil, Babassu Oil, Borage Oil, Butter, C12-C18 Acid Triglyceride, Camellia Oil, Canola Oil, Capric / Capric Triglyceride / Lauric, Capryl Triglyceride / Capric / Linoleic, Caprylic / capric / stearic, caprylic / capric, Carrot Oil, Oil cashew nut oil, castor oil, oil Cherry Stone, chia oil, cocoa butter, coconut oil, Oil Cod Liver , Germ Oil, Corn Oil, Corn Oil Cottonseed Triglyceride C10-C18, egg oil, epoxidized soybean oil, oil of evening primrose, Glyceryl Triacetyl Hydroxystearate, Glyceryl Triacetatil Ricin oleate, glycosphingolipids, Oil Grape Seed Oil, Hazelnut, Lipids Human Placenta, Safflower Oil Hybrid Seed Oil Sunflower Hybrid, hydrogenated Castor Oil, laurate hydrogenated Castor Oil, Coconut Oil hydrogenated Oil, hydrogenated cottonseed, Hydrogenated C12-C18 Triglycerides, Hydrogenated Fish Oil, Hydrogenated Butter, Hydrogenated Menhaden Oil, Hydrogenated Mink Oil, Hydro Orange Tosco Oil enado, Seed Oil Hydrogenated Palm Oil, Hydrogenated Palm Oil, Peanut Hydrogenated, shark liver oil Hydrogenated, hydrogenated soybean oil, hydrogenated tallow, Hydrogenated Vegetable Oil, Lard, lauric triglyceride / Palmitic / Oleic, Lanolin and Derivatives of Lanolin, Lesquerella Oil, Linseed Oil, Macadamia Nut Oil, Stroked Soybean Oil, Prairie Foam Seed Oil, Menhaden Oil, Mink Oil, Moringa Oil, Mortierella Oil, Patagonian Oil Animal Beef, Triglyceride Oleic / Linoleic, Triglyceride Oleic / palmitic / Lauric / Myristic / Linoleic, oleostearin, peel oil from olives, olive oil, Lipids omental oil Tosco of orange oil, palm kernel oil, palm oil , Peach Nut Oil, Peanut Oil, Penjawar Djambi Oil, Penadesma Butter, Phospholipids, Pistache Nut Oil, Placental Lipids, Seed Oil Colaza bran oil and rice oil, safflower oil, sesame oil, liver oil Cod, Shea Butter, soybean oil, sphingolipids, Oil Sunflower Seed Oil, Sweet Almond Oil, Resin, Sebo, Tribehenin, Tricaprin , Tricaprylin, Triheptanoin, Trihydroxymethoxystearin, Trihydroxystearin, Triisononanoin, Trisuriarin, Trilaurin, Trilinolein, Trinolenin, Trimiristin, Trioctanoin, Triolein, Tripalmitin, Tricebasin, Tristearin, Triundecanoin, Vegetable Oil, Walnut Oil, Bran and Wheat Lipids, Germ Oil Wheat, Zadoari oil, and the like, as well as mixtures thereof.
Fatty Acids: Arachidic Acid, Arachidonic Acid, Behenic Acid, Capric Acid, Caproic Acid, Capric Acid, Coconut Acid, Corn Acid, Cottonseed Acid, Hydrogenated Coconut Acid, Hydrogenated Menhaden Acid, Hydrogenated Tallow Acid, Hydroxystearic Acid, Isostearic Acid, Lauric Acid, Linoleic Acid, Linolenic Acid, Linseed Acid, Miristic Acid, Oleic Acid, Palmitic Acid, Palm Nugite Acid, Pelargonic Acid, Ricinoleic Acid, Soybean Acid, Stearic Acid, Oil Acid of Resin, Sebum Acid, Undecanoic Acid, Undecylenic Acid, Wheat Germ Acid and the like as well as mixtures thereof.
Fatty Alcohols: Behenyl Alcohol, Alcohols
C8-C11; C12-C13 Alcohols, C12-C15 Alcohols, C12-C16 Alcohols, C14-C15 Alcohols, Caprilic Alcohol, Cetearyl Alcohol, Cetyl Alcohol, Coconut Alcohol, Decyl Alcohol, Hydrogenated Tallow Alcohol, Lanolin Alcohol, Lauryl Alcohol, Miristyl Alcohol , Oleyl Alcohol, Palm Alcohol, Palm Pepita Alcohol, Stearyl Alcohol, Tallow Alcohol, Tridecyl Alcohol and the like as well as mixtures thereof.
Essential Oils: Anise Oil, Balsam Mint Oil, Basil Oil, Bee Balsam Oil, Bergamot Oil, Birch Oil, Bitter Almond Oil, Bitter Orange Oil, Calendula Oil, California Nut Oil , Caraway Oil, Cardamom Oil, Chamomile Oil, Cinnamon Oil, Wild Salvia Oil, Clove Oil, Cilantro Oil, Cypress Oil, Eucalyptus Oil, Fennel Oil, Gardenia Oil, Oil Geranium, Ginger Oil, Grapefruit Oil, Hyptis Oil, Indian Bush Oil, Jasmine Oil, Hemebro Oil, Kiwi Oil, Laurel Oil, Lavender Oil, Lemongrass Oil, Lemon Oil, Linden Oil, Ligature Oil, Orange Tangerine Oil, Matriacaria Oil, Musk Rose Oil, Nutmeg Oil, Olibanum, Orange Flower Oil, Orange Oil, Patchouli Oil, Penroyal Oil, Peppermint Oil, Oil of Pine, Pine Tar Oil, Rose Hip Oil, Rosemary Oil, Rose Oil, Rue Oil, Salvia Oil, Zambuco Oil, Sandalwood Oil, Sasafras Oil, White Spruce Oil, Mint Oil Green, Sweet Marjoram Oil, Sweet Violet Oil, Tar Oil, Tea Tree Oil, Thyme Oil, Wild Mint Oil, Yarrow Oil, Ylang Ylang Oil and the like, as well as mixtures thereof.
Preferred natural oils or fats include, but are not limited to, avocado oil, apricot oil, babassu oil, borage oil, camellia oil, canola oil, castor oil, coconut oil, corn oil, cottonseed oil, afternoon primrose oil, hydrogenated cottonseed oil, hydrogenated palm kernel oil, beaten soy bean oil, prairie foam oil, palm kernel oil, phospholipids, oil rapeseed, palmitic acid, stearic acid, linoleic acid, stearyl alcohol, lauryl alcohol, myristyl alcohol, behenyl alcohol, rose hip oil, sunflower oil, soy bean oil, and mixtures thereof.
The amount of a sterol or sterol derivative or of a mixture of sterols or sterols derivatives in the oil in water emulsion composition can be from about 0.1 weight percent to about 10 weight percent, more specifically from about 0.5 percent by weight to about 5 percent by weight, and even more specifically from about 0.8 percent by weight to about 3 percent by weight. As used herein, the suitable sterol or sterol derivative includes, but is not limited to the following materials: -teleles having a tail on position 17 that do not have polar groupsfor example, cholesterol, sitosterol, stigmaterol and ergosterol, as well as esters of lanosterol / cholesterol C10-C30, cholecalciferol, cholesteryl hydroxystearate, cholesteryl isostearate, cholesteryl stearate, 7-dihydrocholesterol, dihydrocol is toluene, dihydrocholesteryl octadecanoate, dihydrolanoesterol, dihydrolansteryl octyl decanoate, ergocalciferol, resin oil sterol, soy sterol acetate, latherterol, soy sterol, avocado sterols, sterol sterols, sterol esters, avocadine, lanolin, and the like, as well as mixtures thereof.
The amount of the emulsifying surfactant having a lipophilic hydrophilic balance range of about 7 to about 18 in the oil-in-water emulsion composition can be from about 0.5 to about 20 weight percent, more specifically, from from about 1 to about 15 percent by weight, and even more specifically from about 3 to about 10 percent by weight. Emulsifying surfactants are typically employed in cosmetic preparations to form multi-component emulsions. The immiscible phase, such as an oil, is dispersed as drops in the continuous phase, such as water. As used herein, suitable surfactants include, but are not limited to the following materials: PEG-6 Esters of Almond Oil, PEG-6 Esters of Apricot Bone Oil, Esters PEG-11 of Avocado Oil, Beheneth- 5, Beheneth-10, Beheneth-20, Glycol Ester of C18-C3S Acid, Ester PEG-8 Esteroyl Acid Calcium Lactylate, Glyceryl ACeite of Cañóla, Esters PEG-4 Capric / Carpyl Triglyceride, Beheneth-5, Beheneth- 10, Beheneth-20, Cetearyl Glycoside, Ceteh-1, Ceteth-2, Ceteth-3, Ceteth-4, Ceteth-5, Ceteth-6, Ceteth-10, Ceteth-12, Ceteth-15, Ceteth-16, Phosphate from Cetilo, Coleth-10, Coleth-20, Coleth-24, Coceth-3, Coceth-5, Coceth-8, Coceth-10, Corn Glycerides, PEG-6 Corn Oil Esters, PEG-8 Oil Esters of Corn, Cottonseed Glyceride, C9-C ?: L Pareth-3, C9-C ?: L Pareth-6, C9-Cn Pareth-8, Cn-C15 Pareth-3, Cn-C15 Pareth-5, Cn-C15 Pareth-7, C ^ -C ^ Pareth-9, Cu-C15 Pareth-12, C ^ -C ^ Pareth-15, CX-C15 Pareth-20, C ?: L-C21 Pareth-3 , C ^ -C ^ Pareth-10, C12-C13 Pareth-3, ci2_ i3 Pareth-7, C12-C13 Pareth-9, C12-C13 Pareth-15, C12-C15 Pareth-2, C12-C15 Pareth-3 , C12-C15 Pareth-4, C12-C15 Pareth-5, C12-C15 Pareth-7, C12-C15 Pareth-9, C12-C15 Pareth-11, C12-C15 Pareth-12, C14-C15 Pareth-7, C14-C15 Pareth-11, C14-C15 Pareth-13, C20-C40 Pareth-3, C20-C40 Pareth-10, C30-C50 Pareth-3, C30-C50 Pareth-10, C40-C60 Pareth-3, C40 -C60 Pareth-10, C12-C15 Pareth-2 Phosphate, DEA-Cetyl Phosphate, DEa-01eth-3 Phosphate, DEA-Oleth-10 Phosphate, Deceth-4, Deceth-6, Deceth-4 Phosphate, Deceth-6 Phosphate , Dextrin Palmitate, Decetearety-10 Phosphate, Dicetyl Phosphate, Diethylaminoethyl Cocoate, Diuethylaminoethyl PEG-5 Cocoate, Diethylaminoethyl PEG-5 Laurate, Diethylaminoethyl Stearate, Diglyceryl Caprilate, Dihydrocholeth-15, Dihydrocoleth-20, Dihydrocoleth-30, Dialaureth-4 Phosphate, Dilaureth-10 Phosphate, Dimethicone Copolyol Methyl Ether, Dimethyl Octinediol, Dinonoxynol-9 Citrate, Dinonoxynol-4 Phosphonate, Dioleth-8 Phosphate, Disodium Lauryl Phosphate, Disodium P EG-8 Glyceryl Caprilate / Caparate, Dodoxinol-5, Dodoxinol-6, Dodoxinol-7, Dodoxinol-9, Dodoxinol-12, NF Emulsifying Wax, Glicereth-20 Stearate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprilate, Glyceryl Caprilate / Caprate , Glyceryl Cocoate, Glyceryl Erucate, Glyceryl Hydrogenated Rosinate, Glyceryl Hidoxystearate, Glyceryl Isostearate, Glyceryl Lanolate, Glyceryl Laurate, Glyceryl Laurate / Oleate, Glyceryl Laurate SE, Glyceryl Linoleate, Glyceryl Linolenate, Glyceryl Montanato, Glyceryl Myristate, Glyceryl Oleate, Glyceryl Oleate SE, Glyceryl Palmitate / Stearate, Glyceryl Ricinoleate, Glyceryl Rosinate, Glyceryl / Sorbitol Oleate / Hydroxystearate, Glyceryl Stearate, Glyceryl Stearate SE, Glycol Stearate SE, Hydrogenated Cottonseed Glyceride, Laneth-5 Hydrogenated, Laneth-20 Hydrogenated, Glyceride Hydrogenated Butter, Hydrogenated Lecithin, Hydrogenated Palm Glyceride, Hydrogenated Palm / Palm Kernal Oil PEG-6 Esters, Hydrogenated Soy Glyceride, T alloweth-12 Hydrogenated, Talloweth-60 Hydrogenated Glycol Mirsityl, Hydrogenated Tallow Glyceride, Hydrogenated Vegetable Glyceride, Phosphate Hydrogenated Vegetable Glycerides, Hydroxymethyl Phosphate, Hydroxylated Lecithin, Isoceteareth-8 Stearate, Isosceteth-10, Isoceteth-20, Isoceteth-10 Stearate , Isodeceth-4, Isodeceth-5, Isodeceth-6, Isolaureth-3, Isolaureth-6, Isolaureth-10, Isosteareth-2, Isosteareth-3, Isosteareth-10, Isostearath-12, Isosteareth-20, Isosteareth-6 Carboxylic Acid, Isosteareth-11 Carboxylic Acid, Isosteareth-10 Stearate, Laneth-5, Laneth-10, Laneth-15, Laneth-16, Laneth-4 phosphate, Lanolin, Laureth-1, Laureth-2, Laureth-3, Laureth-4, Laureth-5, Laureth-6, Laureth-7, Laureth-8. , Laureth-9, Laureth-10, Laureth-11, Laureth-12, Laureth-13, Laureth-14, Laureth-15, Laureth-16, Laureth-3 Carboxylic Acid, Lauryl Phosphate, Lecithin, Manteran Laurate, Meroxapol 105, Meroxapol 108, Meroxapol 174, Meroxapol 251, Meroxapol 252, Meroxapol 311, Meroxapol 312, Esters PEG-13 of Mink Oil, Mireth-3, Mireth-5 Mireth-5, Mireth-10, Noneth-8, Nonoxilol-1, Nonoxynol-2, Nonoxynol-3, Nonoxynol-4, Nonoxynol-5, Nonoxynol-6, Nonoxynol-7, Nonoxynol-8, Nonoxynol-9, Nonoxynol-10, Nonocxinol-11, Nonoxin-12, Nonoxynol-13, Nonoxynol- 14, Nonoxynol-15, Nonoxynol-18, Nonoxynol-20, Nonoxynol-6 Phosphate, Nonoxynol -9 Phosphate, Nonoxynol-10 Phosphate, Nonyl Nonoxynol-5, Nonyl Nonoxynol-10, Nonyl Nonoxynol-7 Phosphate, Nonyl Nonoxynol-9 Phosphate, Nonyl Nonoxynol-10 Phosphate, Octoxyglyceryl Behenate, Octylglyceryl Palmitate, Octoxynol-1, Octoxynol-3 , Octoxynol-5, Octoxynol-7, Octoxynol-8, Octoxynol-9, Octoxynol-10, Octoxynil-11, Octoxynol-12, Octoxynil-13, Octoxynol-16, Octoxynol-20, Octoxynol-9 Carboxylic Acid, Octyldodeceth-16 , Octyldodeceth-20, Oleth-2, Oleth-3, Oleth-4, 01eth-5, Oleth-6, Oleth-7, Oleth-8, Oleth-9, Oleth-10, 01eth-12, Oleth-15, Oleth -16, Oleth-20, Oleth-2 Phosphate, Oleth-3 Phosphate, Oleth-4 Phosphate, Oleth-10 Phosphate, Oleth-20 Phosphate, PEG-6 Olive Oil Esters, PEG-10 Esters of Olive Oil, Palm Glyceride, PEG-6 Esters of Peanut Oil, PEG-20 Almond Glycerides, PEG-60 Almond Glycerides, PEG-11 Avocado Glycerides, PEG-6 Beeswax, PEG Beeswax - 8, Behenato PEG-8, Caprate PEG-8, Caprilato PEG-8, Caprato / Capril ato PEG-8, Capric / Capric Glycerides PEG-8, Capric / Capric Glycerides PEG-8, Castor Oil PEG-2, Castor Oil PEG-3, Castor Oil PEG-4, Castor Oil PEG-5, Oil of Castor Oil PEG-8, Castor Oil PEG-9, Castor Oil PEG-10, Castor Oil PEG-11, Castor Oil PEG-15, Castor Oil PEG-20, Castor Oil PEG-25, Oil Castor Oil PEG-30, Castor Oil PEG-33, Castor Oil PEG-35, Castor Oil PEG-36, Ester C12-C18 PEG-8, Cocamide PEG-3, Cocamide PEG-5, Cocamide PEG-6, Cocamide PEG-7, Cocamide PEG-11, Cocamine PEG-2, Cocamine PEG-3, Cocamine PEG-5, Cocamine PEG-10, Cocamine PEG-15, Cocamine PEG-20, Cocamine Oleate / Phosphate PEG-15, Glycerides of Butter of Cocoa PEG-75, Cocoato PEG-5, Cocoato PEG-8, Cocoato PEG-15, Esters of Coconut Oil PEG-10, Cocopolyamine PEG-15, Glycerides of Corn PEG-20, Glycerides of Corn PEG-60, Dicocoato PEG-8, Diisononanotate PEG-2, Diisostearate PEG-8, Dilaurate PEG-2, Dilaurate PEG-4, Dilaurat or PEG-6, Dilaurate PEG-8, Dilaurate PEG-12, Dilaurate PEG-20, Dilaurate PEG-32, Dioctanoate PEG-2, Dioleate PEG-4, Diolateate PEG-6, Dioleate PEG-8, Dioleate PEG-10, PEG-12 Dioleate, PEG-20 Dioleate, PEG-32 Dioleate, PEG-3 Dipalmitate, PEG-13 Diphenyloyl Propane, PEG-2 Distearate, PEG-3 Distearate, PEG-4 Distearate, PEG-6 Distearate, PEG-8 Distearate , PEG-9 Distearate, PEG-12 Distearate, PEG-20 Distearate, PEG-32 Distearate, PEG-8 Ditalate, PEG-12 Ditalate, PEG-8 Di / Triricinoleate, PEG-60 Latex Glyceride, Glyceryl Cocoate PEG-7, Glyceryl Dioleate PEG-12, Glyceryl Isostearate PEG-15, Glyceryl Isostearate PEG-20, Glyceryl Laurate PEG-12, Glyceryl Laurate PEG-20, Glyceryl Oleate PEG-10, Glyceryl Oleate PEG-15, Glyceryl Oleate PEG- 20, Glyceryl Ricinoleate PEG-15, Glyceryl Ricinoleate PEG-20, Glyceryl Sisquioleate PEG-5, Glyceryl Stearate PEG-5, Glyceryl Stearate PEG-10, Glyceryl Triisostearate PEG-5, Glyceryl Trioleate PEG-25, Hydrogenated Castor Oil PE G-5, PEG-16 Hydrogenated Castor Oil, PEG-20 Hydrogenated Castor Oil, PEG-25 Hydrogenated Castor Oil, PEG-30 Hydrogenated Castor Oil, PEG-35 Hydrogenated Castor Oil, PEG-40 Hydrogenated Castor Oil, PEG-8 Fish Glycerides, Hydrogenated Lanolin PEG-5, PEG-10 Hydrogenated Lanolin, PEG-20 Hydrogenated Lanolin, PEG-24 Hydrogenated Lanolin, PEG-20 Hydrogenated Palm Oil Glycerides, PEG-13 Hydrogenated Seal Amide, PEG-8 Hydrogenated Sebum Amina, PEG-10 Hydrogenated Sebum, PEG-15 Hydrogenated Tallow Amino, PEG-20 Hydrogenated Tallow Amina, PEG-15 Hydroxystearate, PEG-6 Isolauryl Thioether, PEG-8 Isolauryl Thioether, PEG-10 Isolauryl Thioether, PEG-6 Isopalmitate, Isostearate PEG-4, Isostearate PEG-6, Isostearate PEG-8, Isostearate PEG-10, Isostearate PEG-12, Acid of Jojoba PEG-15, Acid of Jojoba PEG-26, Acid of Jojoba PEG-40, Alcohol of Jojoba PEG - 15, Jojoba Alcohol PEG-26, PEG-5 Lanolate, PEG-10 Lanolate, PEG-20 Lanolate, PEG-5 Lanolin, PEG-10 Lanolin, PEG-Lanolin 20, Lanolin PEG-24, Lanolin PEG-27, Lanolin PEG-30, Lanolin PEG-40, Wax Lanolin PEG-75, Lauramide PEG-3, Lauramide PEG-5, Lauramide PEG-6, Laurato PEG-2, Laurato PEG-4, Laurato PEG-6, Laurato PEG-8, Laurato PEG-9, Laurato PEG-10, Laurato PEG-12, Laurato PEG-14, Laurato SE PEG-2, Tartarate / Laurato PEG-6, Linoleate PEG- 8, Linoleate PEG-8, Methyl Glucose Distearate PEG-20, Methyl Glucose Sesquicaprilat / Sesquicaprate PEG-20, Methyl Glucose Sesquilaurate PEG-20, Methyl Glucose Sesquistearate PEG-20, Glycerides Mink PEG-13, Myristate PEG-8, Myristate PEG-20, Octanoate PEG-4, Octanoate PEG-5, Octanoate PEG-13, Oleamide PEG-2, Oleamide PEG-4, Oleamide PEG-5, Oleamide PEG-6, Oleamide PEG-7, Oleamide PEG-9, Oleamine PEG-2, Oleamine PEG-5, Oleamide PEG-15, Oleate PEG-2, Oleate PEG-3, Oleate PEG-4, Oleate PEG-5, Oleate PEG-6, Oleate PEG-7, Oleate PEG-8, Oleate PEG-9, Oleate PEG-10, Oleate PEG-11, Oleate PEG-12, Oleate PEG-14, Oleate PEG-15, Oleate PEG-20, Oleate SE PEG-2, Glice Rites of Olive PEG-10, Palmitate PEG-6, Palmitate PEG-18, Palmitate PEG-20, Palm Pepita Glycerides PEG-12, Palm Pepita Glycerides PEG-45, Phytosterol PEG-25, Polyglyceryl-2 Laurato PEG -10, Gl iceri 1 / Sorbitol Hydroxystearate / Isostearate PEG-3 / PEG-2, Glyceryl Stearate PEG-20-PEG-10, Proline Linoleate PEG-4, Proline Linoleate PEG-4, Propylene Glycol Cocoate PEG-8, Colza Amide PEG-4, PEG-2 Ricinoleate, PEG-7 Ricinoleate, PEG-8 Ricinoleate, PEG-9 Ricinoleate, PEG-8 Sesquilaurate, PEG-8 Sesquioleate, PEG-6 Sorbitol Beeswax, Sorbitan Beeswax PEG-8 , Sorbitan Beeswax PEG-20, Sorbitol Diisostearate PEG-40, Sorbitol Isostearate PEG-5, Sorbitol Isostearate PEG-20, Sorbitol Oleate PEG-3, Sorbitol Oleate PEG-6, Sorbitol Petrolat PEG-40 , PEG-3 Sorbitol Stearate, PEG-6 Sorbitol Stearate, PEG-30 Sorbitol Tetraoleate, PEG-40 Sorbitol Tetraoleate, PEG-60 Sorbitol Tetraoleate, Sorbitol Tetrastearate n PEG-60, Sorbitan hexazol PEG-40, Sorbitan hexazollate PEG-50, Sorbitol Laurato Tetraoleate PEG-30, Soy Amines PEG-5, Soy Amines PEG-8, Soy Amines PEG-10, Amine Soy PEG-15, Soy Sterol PEG-5, Soy Sterol PEG-10, Soy Sterol PEG-16, Soy Sterol PEG-25, Estearated PEG-4, Stearamide PEG-5, Stearamide PEG-10, Stearamide PEG -15, Stearate PEG-2, Stearate PEG-3, Stearate PEG-4, Stearate PEG-5, Stearate PEG-6, Stearate PEG-7, Stearate PEG-8, Stearate PEG-9, Stearate PEG-10, Stearate PEG -12, Stearate PEG-14, Stearate PEG-18,
Stearate PEG-20, Stearate E PEG-2, Talate PEG-4, Talate PEG-5, Talate PEG-8, Talate PEG-10, Talate PEG-12, Talate PEG-16, Talate PEG-20, Amide of Sebum PEG -5, Sebo Amide PEG-8, PEG-20 Taloate, PEG-5 Tricapryl Citrate, PEG-5 Tricetyl Citrate, PEG-5 Tridecyl Citrate, PEG-5 Trilauryl Citrate, PEG-5 Trimiristyl Citrate, PEG-5 Triestearyl Citrate , PEG-6 Undecylenate, Pelargonic Acid, Poloxamer 101, Poloxamer 105, Poloxamer 122, Poloxamer 123, Poloxamer 124, Poloxamer 181, Poloxamer 185, Poloxamer 212, Poloxamer 215, Poloxamer 231, Poloxamer 282, Poloxamer 284, Poloxamer 331, Poloxamer 333 , Poloxamer 401, Poloxamer 402, Poloxamer 403, Poloxamer 407, Poloxamine 304, Poloxamine 304, Poloxamine 304, Poloxamine 504, Poloxamine 701, Poloxamine 702, Poloxamine 704, Poloxamine 707, Poloxamine 901, Poloxamine 904, Poloxamine 1101, Poloxamine 1102, Poloxamine 1104, Poloxamine 1301, Poloxamine 1302, Poloxamine 1304, Poloxamine 1307, Poloxamine 1501, Poloxam ina 1502, Poloxamine 1504, Polyglyceryl-3 Beeswax, Polyglyceryl-3 Cetyl Ether, Polyglyceryl-4-Cocoate, Polyglyceryl-10 Decalinoleate, Polyglyceryl-10 Decaleate, Polyglyceryl-10 Decasterate, Polyglyceryl-3 Decyltetradecanoe, Polyglyceryl-2-Diisosterate, Polyglyceryl -3 Diisostearate, Polyglyceryl-10 Diisostearate, Polyglyceryl-2 Diolate, Polyglyceryl-3 Diolebate, Polyglyceryl-6 Dioleate, Polyglyceryl-10 Dioleate, Polyglyceryl-3 Distearate, Polyglyceryl-6 Distearate, Polyglyceryl-10 Distearate, Polyglyceryl-10 Heptaolealto, Polyglyceryl -10 Heptaestearate, Polyglyceryl-6 Heaoleate, Polyglyceryl-3 Hydroxylauryl Ether, Polyglyceryl-2-Isostearate, Polyglyceryl-4-Isostearate, Polyglyceryl-6-Isostearate, Polyglyceryl-2-Lanolin Alcohol Ether, Polyglyceryl-10-Laurate, Polyglyceryl-4 Lauryl Ether, Polyglyceryl- 10 Myristate, Polyglyceryl-2 Oleate, Polyglyceryl-3 Oleate, Polyglyceryl-4 Oleate, Polyglyceryl-6 Oleate, Polyglyceryl-8 Oleate, Polyglyceryl-10 Oleate, Polyglyceryl-2 Oleyl E ster, Polyglyceryl-4 Oleyl Ether, Polyglyceryl-4-PEG-2 Cocoamide, Polyglyceryl-2-PEG-4 Stearate, polyglyceryl-6-pentaloate, polyglyceryl-10-pentaoleate, polyglyceryl-6-penta-stearate, polyglyceryl-10-penta-stearate, polyglyceryl-2 sesquiisostearate, polyglyceryl-2 sesquioleate, polyglyceryl-2 stearate, polyglyceryl-3 stearate, polyglyceryl-4 stearate, polyglyceryl-8 stearate, polyglyceryl-10 stearate, polyglyceryl-3 stearate SE, polyglyceryl-2-tetraisostearate, polyglyceryl-10-tetraoleate, polyglyceryl- 2-tetra-stearate, polyglyceryl-2-triisostearate, polyglyceryl-10-trioleate, polyglyceryl-6-tristearate, polysorbate 20, polysorbate 21, polysorbate 40, polysorbate 60, polysorbate 61, polysorbate 65, polysorbate 80, polysorbate 81, polysorbate 85, polysorbate 80 acetate, castorate potassium, potassium cetyl phosphate, potassium cocoate, potassium cornate, potassium laurate, potassium myristate, octaxinol-12 potassium phosphate, potassium oleate, potassium palmitate, ricinoleate tásico, potassium stearate, potassium talate, talo potassium, PPG-7-buteth-10, PPG-9-buteh-12, PPG-12-buteth-16, PPG-15-buteth-20, PPG-20-buteth-30 , PPG-24-buteth-27, PPG-26-buteth-26, PPG-28-buteth-35, PPG-25-butyl ether phosphate, PPG-2-ceteareth-9, PPG-4-ceteareth-12, PPG -10-ceteareth-20, PPG-4-ceteth-l, PPG-4-ceteth-5, PPG-4 -ceteth-10, PPG-4-ceteth-20, PPG-5-ceteth-20, PPG-8 -ceteth-l, PPG-8-ceteth-2, PPG-8-ceteth-5, PPG-8-ceteth-10, PPG-8-ceteth-20, PPG-5-ceteth-10 phosphate, PPG-10 cetil phosphate ether, PPG-6 pareth-11 C12-C? a, PPG-2-deceth-10, PPG-4-deceth-4, PPG-6-deceth-4, PPG-6-deceth-9, PPG-8 -deceth-6, PPG-6-decyltetradeceth-12, PPG-6-decyltetradeceth-20, PPG-6-decyltetradeceth-30, PPG-20-decyltetradeceth-10, PPG-24-glycereth-24, PPG-66-glycereth -12, PPG-10 glyceryl ether, PPG-27 glyceryl ether, PPG-55 glyceryl ether, PPG-2 isoceteth-20 acetate, PPG-2-isodeceth-4, PPG-2-isodeceth-6, PPG-2-isodeceth -9, PPG-2-isodeceth-12, PPG-3-isosteareth-9, PPG-4 jojoba acid, PPG-4 jojoba alcohol, PPG-10 jojoba alcohol, PPG-12 -laneth-50, PPG-3-laureth-9, PPG-4-laureth-2, PPG-4-laureth-5, PPG-4-laureth-7, PPG- 5-laureth-5, PPG-25-laureth-25, PPG-7 lauryl ether, PPG-3-mireth-3, PPG-3-mireth-ll, PPG-2-PEG-6 coconut oil ethers, lanolin PPG-12-PEG-50, lanolin oil PPG-12-PEG 65, lanolin oil PPG-40-PEG-60, polyglyceryl-2 ether PPG-8, propylene glycol capreth-4, propylene glycol caprylate, propylene glycol hydroxystearate, propylene glycol isodeceth -4, propylene glycol isodeceth-12, propylene glycol isostearate, propylene glycol laurate, propylene glycol linoleate, propylene glycol linolenate, propylene glycol myristate, propylene glycol oleate, propylene glycol oleate SE, propylene glycol oleth-5, propylene glycol ricinoleate, propylene glycol soyate, propylene glycol stearate, propylene glycol stearate SE, oleate raffinose , sunflower glyceride, sodium caproyl lactylate, sodium caprylate, caprileth-9 sodium carboxylate, sodium castorate, ceteh-13 sodium carboxylate, sulphate co sodium ceth, sodium cocoate, hydrogenated tallow sulfate / sodium coconut, dicenteareth-10 sodium phosphate, sodium isostearaoyl lactylate, sodium laurate, laureth-4 sodium phosphate, sodium lauryl lactylate, sodium laureth-2 sulfosuccinate / MEA, sodium myristate, sodium oleate sodium oleaoyl lactylate, sodium oleth-7 phosphate, sodium oleth-8 phosphate, sodium palmitate, sodium palm quernelate, sodium ricinoleate, sodium stearate, sodium steareth-4 phosphate, sodium stearoyl lactylate, sodium stearoyl sulfate, trideceth sulfate sodium, tridecyl sodium sulfate, sodium undecyl anate, sorbitan-6 srobitan hexaisostearate diisostearate, sorbitan dioleate, sorbitan distearate, sorbitan isostearate, sorbitan laurate, sorbitan oleate, sorbitan palmitate, sorbitan sesquiisostearate, sorbitan sesquioleate, sorbitan sesquisalate , sorbitan stearate, sorbitan triisostearate, sorbitan trioleate, sorbitan trioleate, sorbitan tristearate , soy acid, esteareth-2, esteareth-3, esteareth-4, esteareth-5, esteareth-6, esteareth-7, esteareth-10, esteareth-11, esteareth-13, esteareth-15, esteareth-16, esteareth -20, steareth-21, stearic acid, stearoyl lactylic acid, sucrose cocoate, sucrose quilaurate, sucrose distearate, sucrose laurate, sucrose myristate, sucrose oleate, sucrose palmitate, sucrose polylaurate, sucrose polyilinoleate, sucrose polyoleate, sucrose polystearate, sucrose ricinoleate, sucrose stearate, sunflower seed oil glyceride, resin oil acid, gallow acid, talloweth-6, tallow glyceride, TEA-isostearate, TEA-lauryl lactylate, TEA-myristate, TEA-olateate, TEA-palmitate, TEA-stearate, TEA-talate, TIPA-stearate, triceteareth-4-phosphate, triceth-5-phosphate, trideceth-2, trideceth-3, trideceth-6, trideceth-7, trideceth-9, trideceth-10, trideceth-11, trideceth-12, trideceth-15, trideceth-20, trideceth-3 phosphate, trideceth- 6 phosphite, triisostearin PEG-6 esters, trianeth-4 phosphate, trilaureth-4 phosphate, triolein PEG-6 esters, trioleth-8 phosphate, undecanoic acid, undeceth-5, undecylenet-6, vegetable glyceride phosphate and the like as well as mixtures thereof.
Preferred surfactants include, but are not limited to, emulsifying wax NF, glyceryl stearate, glyceryl stearate SE glycol stearate, glycol stearate SE, glycereth-20, stearate, glyceryl beheneate, glyceryl hydroxystearate, glyceryl laurate SE, glyceryl oleate, glyceryl oleate SE, propylene glycol oleate, propylene glycol oleate SE, propylene glycol stearate, propylene glycol stearate SE, sorbitan stearate, sorbitan trioleate and the like, as well as mixtures thereof.
The amount of humectant in the oil-in-water emulsion composition can be from about 0.1 to about 30% by weight, more specifically from about 0.5 to about 20% by weight, and even more specifically from about from 1 to around 10% by weight. Moisturizers are typically cosmetic ingredients used to increase the water content of the upper layers of the skin. This group of materials includes hydroscopic ingredients primarily. As used herein, humectants include, but are not limited to the following materials: acetamide MEA, aloe vera gel, arginma PCA, chitosan PCA, copper PCA, corn glycerides, dimethyl imidazolinone, fructose, glucamide, glucose, glutamate glucose, glucuronic acid, glutamic acid, glycereth-7, glycereth-12, glycereth-20, gl? cereth-26, glycerin, honey, hydrogenated honey, hydrogenated starch hydrolyzate, hydrolyzed corn starch, lactamide MEA, lactic acid, lactose licina PCA, mannitol, methyl gluceth-10, methyl gluceth-20 PCA, PEG-2 lactamide, PEG-10 propylene glycol, polyamino sugar condensate, potassium PCA, propylene glycol, propylene glycol citrate, saccharide hydrolyzate, saccharide isomer, sodium aspartate , sodium lactate, sodium PCA, sorbitol, TEA lactate, TEA-PCA, urea, xylitol and the like, as well as mixtures thereof.
The amount of oil-in-water emulsion composition can be from about 45 to about 99.5%, more specifically from about 60 to about 98% by weight, and even more specifically from about 75 to about 95. % by weight.
The amount of petrolatum or mineral oil that can be optionally used in the oil-in-water composition can be from about 0 to about 30% by weight, more specifically from about 0 to about 10% by weight, and even more specifically from about 0 to about 5% by weight.
The pH should be adjusted to approximately the pH of the skin with a suitable acid or base. The pH of the composition can be from about 4.0 to about 7.0, more specifically from about 5.0 to about 6.0 and more specifically from about 5.4 to about 5.6. In some product lines, such as certain facial cleansing wipes, it may be desirable to have a pH range of from about 2 to about 8.
In order to better increase benefits for consumers, additional ingredients can be used. The kinds of ingredients and their corresponding benefits include, without limitation: anti acne assets (a product used to reduce the number of acne spots, acne pimples, blackheads and whiteheads, antifoaming agents (reduce the tendency to foaming during the processing), antimicrobial assets, antifungal active, antiseptic assets, antioxidants (product integrity), antioxidants (to avoid oxidation of natural oils and other ingredients in the formula), astringent-cosmetics (induce a tightening or scorching sensation); astringent-drug (a drug product with spillage, discharge or bleeding checks when applied to the skin or mucous membrane and working by means of a coagulating protein); biological additives (increase the functioning or attraction of the consumer of the product by including vitamins), dyes (impart color to the product), deodorants (reduce or eliminate odor) unpleasant and protect against the formation of bad odor on the surfaces of the body); emollients (help maintain the smooth, smooth and supple appearance of the skin through its ability to remain on the surface of the skin or in the stratum corneum to act as lubricants, to reduce flaking, and improve the appearance of the skin ); foam formers (to keep the active ingredients on the skin by producing a continuous film on the skin with drying); fragrances (consumer attraction); natural moisturizing agents (NMF) and other skin moisturizing ingredients known in the art; condoms (prevent microbial contamination and growth); skin conditioning agents; skin exfoliating agents (ingredients that increase the rate of change of skin cells such as alpha hydroxy acids and betahydroxy acids); skin protectors (a drug product which protects the injured or exposed skin or the mucous membrane surface from harmful or annoying stimuli); absorbents (liquids used to dissolve the components found useful in cosmetics or drugs); sunscreens (ingredients that absorb at least 85% of the light in the ultraviolet range at wavelengths of 290 to 320 nanometers, but transmit ultraviolet light at wavelengths longer than 320 nanometers); and surfactants (as cleaning agents, solubilizing agents, suspending agents and wetting agents).
The wet wiping cloths of the present invention comprise a single layer or a layered base sheet containing a liquid. The liquid is typically any solution which can be absorbed into the base sheet of the wet cleaning cloth and can include any suitable components which provide the desired cleaning cloth properties. Typically, the components have included water, emollients, surfactants, fragrances, preservatives, chelating agents, pH buffers or combinations thereof as are well known to those skilled in the art. The liquid also contains certain medications and / or lotions. The emulsion composition of the present invention is more specifically designed to provide improved skin health benefits, such as increased barrier function and skin protection.
The amount of the oil-in-water emulsion composition of the present invention contained within each cleaning cloth may vary depending on the type of material used to provide the cleaning cloth or the cleaning cloth type product, the type of container being used. used to store the wet cleaning cloths, and the desired end use of the wet cleaning cloth. Generally, each cleaning cloth or cleaning cloth type product may contain from about 100 to about 600% by weight and desirably from about 250 to about 450% by weight of liquid based on the dry weight of the cleaning cloth to improve the cleanliness. In a particular aspect, the amount of liquid contained within the cleaning cloth is from about 300 to about 400% by weight and desirably from about 330% by weight based on the dry weight of the wet cleaning cloth. If the amount of liquid is less than the above identified ranges, the cleaning cloth can also be very dry and may not work properly. If the amount of liquid is greater than the ranges identified above, the cleaning cloth may be supersaturated and soaked and the liquid may stagnate at the bottom of the container.
Each wet cleaning cloth is generally rectangular in shape and can have any suitable width and bent lengths. For example, the cleaning cloth may have a split length of from about 2.0 to about 80.0 centimeters and desirably from about 10.0 to about 25.0 centimeters and an unfolded width of from about 2.0 to about 80.0 centimeters and desirably from from around 10.0 to around 25.0 centimeters. Typically, each individual wet cloth is arranged in a folded configuration and stacked on top of each other to provide a stack of wet cleaning cloths. Such bent configurations are well known to those of ordinary skill in the art and include the configurations bent in c, bent in z, bent in fourth and the like. The stack of folded wet cleaning wipes can be placed inside a container, such as a plastic tube to provide a package of wet wiping cloths for eventual sale to the consumer. Alternatively, the wet wiping cloths may include a strip of continuous material which has perforations between each wiping cloth and which can be arranged in a stack or rolled in a roll for the assortment.
However, the product of wet cleaning cloth or cloth type can assume a variety of shapes including but not limited to the generally circular, oval, square or irregularly shaped shape. The size of the type of cleaning cloth or wet cleaning cloth will also vary from the desired end use of the cleaning cloth.
The single or multi-layer base sheet materials of the wet cleaning cloth or cleaning cloth type product of the present invention can be varied to provide different physical properties. The different physical properties which a layer can be configured to provide by selecting the appropriate materials include the softness, elasticity, strength, flexibility, integrity, firmness, absorbency, liquid retention, thickness, resistance to breakage, surface texture, drop, touch, wetting, ability to transmission and the like and combinations thereof. The cleaning cloth may be configured to provide all the desired physical properties within a layer or be configured to provide only specific physical properties within the individual layers of a multi-layer cleaning cloth. For example, wet wiping cloths may include at least one layer of material that is configured to provide strength and elasticity to the wet cleaning cloth and at least one other layer which is configured to provide a soft and gentle wiping surface to the cloth. wet cleaner. Desirably, the wet cleaning cloths provide a smooth cleaning surface for contact with the skin.
The layer or layers of the wet cleaning cloth or the cleaning cloth type products can be made from a variety of materials including meltblown materials, coform materials, air laid materials, bonded and bonded woven materials, hydroentangled materials, materials spun-bonded and the like and may comprise synthetic or natural fibers. Examples of natural fibers suitable for use in the present invention include cellulosic fibers such as wood pulp fibers, cotton fibers, flax fibers, jute fibers, silk fibers and the like. Examples of the thermoplastic polymer fibers suitable for use with the present invention include polyolefins such as polypropylene and polyethylene, polyamides and polyesters such as polyethylene terephthalate. Alternate synthetic fibers which may be suitable include basic nylon and rayon fibers. The layer or layers of the wiping cloth or wet wipe type products may be woven or nonwoven materials. In addition, materials can be formed into balls, such as cotton balls or applied to delivery systems such as scouring applicators.
If a layer of the base sheet is a combination of polymeric and natural fibers, such as polypropylene and cellulosic fibers, the relative percentages of the polymer fibers and natural fibers in the layer can vary over a wide range depending on the characteristics desired of the wet cleaning cloths. For example, the layer may comprise from about 20 to about 95% by weight, desirably from about 20 to about 60% by weight, and more desirably from about 30 to about 40% by weight of polymer fibers based on the dry weight of the layer. Such a layer of natural and polymeric fibers can be manufactured by any method known to those skilled in the art.
Generally, it is desirable that such a layer be formed by a coform process for a more uniform distribution of the polymeric and natural fibers within the layer. Such coform layers are generally manufactured as described in U.S. Patent No. 4,100,324 issued to Anderson et al. On July 11, 1978; U.S. Patent No. 4,604,313 issued to MacFarland et al. on August 5, 1986 and U.S. Patent No. 5,359,624 issued September 27, 1994; all of which are incorporated herein by reference in the extent to which they are consistent therewith.
Typically, such coform layers comprise a matrix formed of melt-blown microfiber thermoplastic polymeric microfibers, such as, for example, polypropylene microfibers and cellulosic fibers, such as, for example, wood pulp fibers. A coform layer is formed by initially forming at least one primary air stream containing the synthetic or polymeric fibers and fusing the first stream with at least one secondary stream of natural or cellulosic fibers. The primary and secondary currents are fused under turbulent conditions to form an integrated stream that contains a homogeneous and complete distribution of the different fibers. The integrated air stream is directed to a forming surface to form the material layer with air. A multiplicity of these coform layers can be formed in succession to provide a fabric of multiple coform layers.
The different fibers in the different layers of the layered base sheet of the present invention, such as the polypropylene and polyethylene microfibers set forth above, typically may not be compatible with each other and may not bond to one another. However, the different fibers may become entangled with one another resulting in adequate securing between the layers. For example, in a layered base sheet containing a coform layer of polyethylene and cellulosic fibers and a coform layer of polypropylene and cellulosic fibers, the polyethylene and polypropylene fibers can become entangled with each other and the cellulosic fibers can bind at least partially to the cellulosic fibers which results in an assurance between the layers.
Such an interlayer and entanglement bond can be increased by means of thermomechanical processes wherein the layered base sheet is passed between a smooth anvil roller and a heated pattern roller. The pattern roller may have any highlighted pattern which provides the desired entanglement and interlayer bond. Desirably, the patterned roller defines a raised pattern which defines a plurality of bonding sites which define a bonding area of between about 4 and about 30% of the total roll area for improved interlayer fastening.
The base sheet for cloths or wet cleaning cloth type products can have a total basis weight of from about 25 to about 120 grams per square meter and desirably from about 40 to about 90 branches per square meter. Such base weight of the layered base sheet can also vary depending on the desired end use of the cleaning cloth or the wiper type products. For example, a base sheet suitable for cleaning the skin can define a basis weight of from about 60 to about 80 grams per square meter and desirably about 75 grams per square meter. In a particular embodiment wherein the base sheet includes the polypropylene coform layers and the cellulosic fibers and the polyethylene and cellulosic fibers, the base sheet in layers defines a basis weight of from about 60 to about 90 grams per meter square and desirably about 80 grams per square meter for improved smoothness and adequate strength.
In a particular embodiment, it is desired that the wet cleaning cloth of the present invention defines a strength sufficient to withstand the forces exerted by the user when the latter is moistened with the solution. For example, the base sheet for wet cleaning cloths or cleaning cloth type products can define a tensile strength of at least about 1.23 newtons per centimeter in the machine direction and at least about 0.70 newtons per centimeter in the direction transverse to the machine. Cleaning cloths or the type of cleaning cloth that has alternate ranges of tensile strength can also be effectively employed. As used herein, the term "machine direction" refers to the direction in which the materials are manufactured while the direction transverse to the machine refers to a direction which is perpendicular to the machine direction.
In a particular embodiment, wherein the base sheet includes the coform layers of polypropylene and cellulosic fibers and polyethylene and cellulosic fibers, the base sheet in layers defines a tensile strength of from about 1.31 to about 3.50 newtons per centimeter in the machine direction and from about 0.84 to about 1.40 newtons per centimeter in the direction of the cross machine and desirably from about 1.58 to about 1.93 newtons per centimeter in the machine direction and from about 0.93 to about 1.11 newtons per centimeter in the cross machine direction. In such a configuration, the coform layer which includes the polypropylene fibers provides the majority of the strength to the base sheet while the coform layer which includes the polyethylene fibers provides a smooth surface for contact with the wearer's skin. Thus, the tensile strength of such a layered base sheet is superior to the tensile strength of a single layer containing polyethylene fibers and which provides a smoother surface than a single layer containing polypropylene fibers.
And emplos
The following examples are presented to provide a more detailed understanding of the invention. The particular materials and parameters are exemplary and are not intended to limit the scope of the invention.
The following formulas are used in examples 1-4:
Formula 1 Percent by Weight Water amount sufic. to 100%
Glycerin 5% Glyceryl stearate SE 3% Borage oil 1% Aloe 0.3% Tocopherol acetate 0.3% pH adjuster suitable for pH 5.5
Formula 2 Percent by Weight Water amount sufic. to 100%
Glycerin 5% Glyceryl stearate SE 3% Borage oil 1% Aloe 0.1% Tocopherol acetate 0.1% PROLIPID 141, (International Specialty Products, Wayne, New Jersey) 1% Petrolatum 1% Soybean oil 0.8% pH adjuster suitable for pH of 5.5 Formula 3 Percent by Weight Water amount sufic. to 100;
Glycerin 5% Glyceryl stearate SE 3% Borage oil 1% Soybean oil 0.8% Aloe 0.3% Tocopherol acetate 0.3% Suitable pH adjuster at pH 5.5
Formula 4 Percent by Weight Water amount sufic. to 100%
Glycerin Glyceryl stearate SE 3% Borage oil 1% Soybean sterol 0.8% PROLIPID 141 (International Specialty Products, Wayne, New Jersey) 1% Aloe 0.3% Tocopherol acetate 0.3% pH adjuster suitable for pH 5.5
Formula 5 Percent by Weight Water amount sufic. to 100%
Lipomicron NSLE (Sederma, Le Perray- en-Yvelines, France) 5%
Formula 6 Percent by Weight Water amount sufic. to 100%
Glycerin 5% Sterol Esters 0.5% Petrolatum 1% Avocadin 0.5% PROLIPID 141 (International Specialty Products, Wayne, New Jersey) i s-
Formula 7 Percent by Weight Water amount sufic to 100%
Glycerin 3.3% Glyceryl stearate SE 1.98% Borage oil 0.66% Soybean sterol 0.53% PROLIPID 141 (International Specialty Products, Wayne, New Jersey) 0.66; Aloe 0.2% 0.2% tocopherol acetate pH adjuster suitable for pH 5.5 Example 1 Cleaner Cloth Enriched with Lipid Increase Skin Barrier against Skin Irritant, Fecal Enzyme and Trypsin
The EpiDermMARCA skin model (from Epi -200, from Mattek Corporation, of Ashland, Maryland), was used to evaluate the ability of cleansing lipid-enriched wipe formulas to increase the skin barrier against trypsin permeation (a skin irritant, fecal enzyme) and avoid an interleukin-la (IL-la) response which is a measure of inflammation.
The test formulas (15 microliters) were added to the surface of the EpiDermMARCA skin model and incubated for 30 minutes at 37 ° C, 5% C02 before dosing with the fecal enzyme, trypsin. The study was conducted using an Epi-200 assay medium devoid of hydrocortisone and a pH indicator that was prepared by the manufacturer. After 30 minutes, the underlying medium was removed and replaced with a fresh preheated medium followed by the application of 10 microliters of 200 μg / ml trypsin. The skin wells were incubated for 6 hours before the underlying medium was removed and stored for further analysis. The medium was assayed for the permeated trypsin content using a fluorescent substrate (Boc-Gin-Ala-Arg-AMC.HCl, from Bachem California, Inc., of Torrance, California) specific for trypsin-like activity. Also, the amount of IL-la in the medium was measured using the commercially available ELISA kits (Quantikine ^ 11 ^ Human IL-la Immunoassay, R &D Systems, of Minneapolis, Minnesota) specific for IL-la to assess the capacity of the formulas to avoid a proinflammatory response by the enzyme in comparison to the control without treatment.
Table 1.1: Irritation: Proinflammatory response (IL-la)
Table 1.2: Permeated Trypsin
Formulas 1 and 2 increased the skin barrier of the EpiDermMARCA skin model against trypsin and reduced the proinflammatory response as measured by IL-la after 6 hours compared to trypsin control.
The 2
Wet Cleaner Cloth Enriched with Lipid Promotes Barrier Repair as Measured by Loss of Transepidermal Aqua (TEWL)
All the studies were carried out in a room at controlled temperature and humidity (71 ° F + 5 ° F, 40 + 5% relative humidity).
2A. Twenty microliters of a moist cleaning cloth prototype formula were applied topically to the palmar forearm of 24 female panelists followed by abrasion with an emery cloth. Transepidermal water loss measurements were obtained using a Dermalab evaporimeter pre and post abrasion and 1.2 and 4 hours after the application of the formulas. The mean transepidermal water loss values are expressed in Table 2.1. Repeated ANOVA measurements were used to adjust for transepidermal water loss measurements.
Table 2.1: TEWL (q / m2 / hr) Results - Wet Cleaning Cloth Formulas
* Denotes significantly different than the untreated site.
All moist cleansing formulas enriched with lipid repaired the skin barrier compared to the untreated site in 1, 2 and 4 hours after the application of the formulas as measured by transepidermal water loss.
2B. The mean transepidermal water loss values following the same study design described above are expressed in Table 2.2. Transepidermal abrasion water loss values (baseline) were subtracted from all other readings as to correct for the underlying subject-to-subject differences. All statistical evaluations were made on these differences.
Table 2.2: TEWL (g / m / hr) Results - Wet Wiper Cloth Formulas
* Denotes significantly different than the untreated site. ** Denotes significantly different from formula 5.
Both formulas 5 and 6 repaired the skin barrier compared to the untreated site as measured by transepidermal water loss. In addition, formula 6 repaired the barrier significantly better than formula 5. Formula 5 contains lipmicron NSLE, a Sederma product (Le Perray-en-Yvelines, France) at the recommended level of use that is marketed as a product for the protection of the cutaneous barrier.
Example 3
Cleansing Cloth Formulas Enriched with Lipid Improve Skin Moisture as Measured by Conduct All studies were conducted in a room at controlled temperature and humidity (71 ° F + 5 ° F, 40 + 5% relative humidity) .
3A. Twenty microliters of wet cleaning cloth prototype were applied topically to the palmar forearm. The conduction measurements were obtained using the Skicon instrument before the application of the formulas 1, 2, 4 and 6 hours after the application. The average conduction values are expressed in Table 3.1. A comparison was applied in the direction of the pair for each period of time using the non-varied ANOVA.
Table 3.1: Driving-Wet Wiper Cloth Formulas
* Denotes significantly different than the untreated site.
All the wet cleaning cloth formulas significantly increased the wetting of the skin at 1, 2, 4 and 6 hours after the application of the formulas compared to the untreated site.
3B. The average conduction values following the same study design described above with the exception that a conduction measurement was not obtained at 6 hours after the application are expressed in Table 3.2. The preapplication conduction values (baseline) were subtracted from all other readings as to correct for the underlying subject-to-subject differences. All statistical evaluations were made on these differences.
Table 3.2: Driving - Wet Wiper Cloth Formulas
* Denotes significantly different than the untreated site.
Formula 6 significantly increased skin wetting at 1, 2 and 4 hours after the application of the formulas compared to the untreated site. Formula 5 failed to increase the wetting of the skin at any of the times tested. Formula 5 contains Lipomicron NSLE, a Sederma product (Le Perray-en-Yvelines, France) at the recommended level of use that is marketed as a product for the protection of the skin barrier.
Example 43
Repetitive Cleansing with Lipid Enriched Formulas on a Cleansing Cloth Base Sheet Leaves Skin in a Natural Healthy State by Not Damaging the Skin Barrier
All studies were conducted in a room at controlled temperature and humidity (71 ° F + 5 ° F, 40 + 5% relative humidity).
Cleansing cloths treated with the lipid-enriched formulas were repeatedly rubbed on the palmar forearm of 18 panelists in four cycles for a total of 60 times a day for a duration of 4 days. Transepidermal water loss measurements were taken using the Dermalab evaporimeter at the beginning and end of each day. The table given below shows the transepidermal water loss values at the beginning and at the completion of the study. Repeated ANOVA measurements were used to adjust for repeated transepidermal water loss measurements.
Table 4.1: TEWL Values (g / m2 / hour) At the Beginning and at the End of a Four Day Cleanup Cycle
Final Base Day 4 Media Media
Not treated 6.5 4.7 Formula 1 6.7 5.8 * Formula 3 6.6 5.1 * Formula 7 6.5 5.7 *
* Denotes not significantly different from the non-treated.
Cleansing cloths that are treated with lipid-enriched formulas leave the skin in a healthy and natural state by not damaging the skin barrier after a repetitive cleaning for the duration of 4 days.
Thus the examples representatively illustrate that the emulsion composition of the present invention can provide a wiping cloth or wet wiping type products that have improved health benefits for the skin as well as providing improved protection of the barrier function of the skin. the skin. Therefore, different aspects of the present invention can advantageously provide wet cleaning cloths or cleaning cloth type products, when compared to conventional wet cleaning cloths, which have health benefits for the skin and barrier function protection of the skin. improved skin Such wet cleaning cloths can be used for cleaning cloths for babies, cleaning cloths for adults, hand wipes, face cleaning cloths, cosmetic cleaning cloths, household cleaning cloths, industrial cleaning cloths and the like.
Although the invention has been described in detail with respect to specific aspects thereof, it will be appreciated by those skilled in the art, upon achieving an understanding of the foregoing, that alterations, variations and equivalents of these aspects can easily be conceived. Therefore, the scope of the present invention should be evaluated as that of the appended claims and any equivalents thereof.
Claims (55)
1. A product of the type of cleaning cloth or wet cleaning cloth that increases the skin barrier having at least one layer and an oil-in-water emulsion composition comprising: from about 0.1 to about 30% by weight of natural fats or oils; from about 0.1 to about 10% by weight of sterol or sterol derivative; from about 0.1 to about 30% by weight of humectant; from about 0.5 to about 20% by weight of an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to about 18; Y from about 45 to about 99.5% by weight of water.
2. The product, as claimed in clause 1, characterized in that said water is a mixture of alcohol and water.
3. The product, as claimed in clause 2, characterized in that said alcohol is less than about 70% by weight of said mixture of alcohol and water.
4. The product, as claimed in clause 1, characterized in that said emulsion composition has a pH ranging from about 4 to about 7.
5. The product, as claimed in clause 1, characterized in that the amount of said oil-in-water emulsion composition contained within each product of type of cleaning cloth or wet cleaning cloth is from about 150 to about 600% by weight based on the weight of said product.
6. The product, as claimed in clause 1, characterized in that the natural oil or fat is borage oil.
7. The product, as claimed in clause 1, characterized in that the natural oil or fat is avocado oil.
8. The product, as claimed in clause 1, characterized in that the natural oil or fat is sunflower oil.
9. The product, as claimed in clause 1, characterized in that the sterol or the sterol derivative is soy sterol.
10. The product, as claimed in clause 1, characterized in that the sterol or the sterol derivative is avocado sterol.
11. The product, as claimed in clause 1, characterized in that the sterol or the sterol derivative is cholesterol.
12. The product, as claimed in clause 1, characterized in that the humectant is glycerin.
13. The product, as claimed in clause 1, characterized in that the humectant is sorbitol.
14. The product, as claimed in clause 1, characterized in that the humectant is propylene glycol.
15. The product, as claimed in clause 1, characterized in that said emulsifying surfactant is glyceryl stearate SE.
16. The product, as claimed in clause 1, characterized in that said emulsifying surfactant is NF emulsifying wax.
17. The product, as claimed in clause 1, characterized in that said emulsifying surfactant is propylene glycol oleate SE.
18. The product, as claimed in clause 1, characterized in that said composition further comprises from about 0.1 to about 30% by weight of petrolatum or mineral oil.
19. A method for making a cleaning cloth or wet cleaning cloth product comprising: (a) providing at least one single layer fabric of a nonwoven material; (b) applying an oil-in-water emulsion composition comprising a natural fat or oil, a sterol or a sterol derivative, a humectant, and an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to around 18, to the non-woven material; (c) cutting said fabric into individual sheets to provide wet cleaning or wiping cloth products.
20. The method, as claimed in clause 19, characterized in that said oil-in-water emulsion composition is absorbed in said product.
21. An oil-in-water emulsion composition comprising from about 0.1 to about 30% by weight of natural fats or oils, from about 0.1 to about 10% by weight of sterol or sterol derivative, from about 0.1 to about 30% by weight of humectant, from about 0.5 to about 20% by weight of emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to about 18, and from around 45 to about 99.5% by weight of water.
22. The composition, as claimed in clause 21, characterized in that said water is a mixture of alcohol and water.
23. The composition, as claimed in clause 22, characterized in that said alcohol is less than about 70% by weight of said mixture of alcohol and water.
24. The composition, as claimed in clause 21, characterized in that said emulsion composition has a pH ranging from about 4 to about 7.
25. The composition, as claimed in clause 21, characterized in that said natural fats or oils are selected from the group consisting of avocado oil, apricot oil, babassu oil, borage oil, camellia oil, canola oil, castor oil, coconut oil, corn oil, cottonseed oil, afternoon primrose oil, hydrogenated cottonseed oil, hydrogenated palm kernel oil, beaten soy bean oil, foam oil prairie, palm kernel oil, phospholipids, rapeseed oil, palmitic acid, stearic acid, linoleic acid, stearyl alcohol, lauryl alcohol, myristyl alcohol, benenyl alcohol, rose hip oil, sunflower oil, soy bean oil and mixtures thereof.
26. The composition, as claimed in clause 21, characterized in that said sterol or sterol derivative is selected from the group consisting of cholesterol, cytosterol, esteem sterol, herbalterol, latherterol, soy sterol, avocado sterols, cholesterol sterols , esters of sterol, avocadine, lanolin and mixtures thereof.
27. The composition, as claimed in clause 21, characterized in that the amount of oils or fats is from about 0.5 to about 10% by weight.
28. The composition, as claimed in clause 21, characterized in that the amount of natural fats or oils is from about 1 to about 5%.
29. The composition, as claimed in clause 21, characterized in that it also comprises from about 0 to about 30% by weight of petrolatum or mineral oil.
30. The composition, as claimed in clause 21, characterized in that the amount of emulsifying surfactant is from about 1 to about 15% by weight.
31. The composition, as claimed in clause 21, characterized in that the amount of said humectant is from about 0.5 to about 20% by weight.
32. The composition, as claimed in clause 21, characterized in that it comprises about 1% by weight of borage oil, about 0.8% by weight of soy sterol, about 5% by weight of glycerin, about 3%. % by weight of glyceryl stearate SE, and about 90.2% of water.
33. The composition, as claimed in clause 32, characterized in that said emulsion composition has a pH of about 5.5.
34. The composition, as claimed in clause 21, characterized in that it comprises about 1% by weight of borage oil, about 0.8% by weight of soy sterol, about 5% by weight of glycerin, about 3%. % by weight of glyceryl stearate SE, about 1% by weight of USP petrolatum, about 1% by weight of PROLIPID 141 and about 88.9% by weight of water.
35. The composition, as claimed in clause 34, characterized in that the emulsion composition has a pH of about 5.5.
36. The composition, as claimed in clause 21, characterized in that it comprises about 0.5% by weight of avocadine, about 0.5% by weight of sterol esters, about 5% by weight of glycerin, about 1% by weight weight of glyceryl stearate in the form of PROLIPID 141 and about 92% by weight of water.
37. The composition, as claimed in clause 36, characterized in that said emulsion composition has a pH of about 5.5.
38. The composition, as claimed in clause 21, characterized in that it comprises about 10% by weight of sunflower oil, about 1% by weight of cholesterol, about 3% by weight of glycerin, about 5% by weight. Wax weight emulsifier NF, and about 81% by weight of water.
39. The composition, as claimed in clause 38, characterized in that said emulsion composition has a pH of about 5.5.
40. The composition, as claimed in clause 21, characterized in that it comprises about 5% by weight of avocado oil, about 1% by weight of latherterol, about 1% by weight of sorbitol, about 5% by weight. weight propylene glycol oleate SE, and about 88% by weight of water.
41. The composition, as claimed in clause 40, characterized in that said emulsion composition has a pH of about 5.5.
42. The composition, as claimed in clause 21, characterized in that it comprises about 10% by weight of palm kernel oil, about 1% by weight of latherterol, about 15% by weight of hydrogenated starch hydrolyzate, about 15% by weight of glyceryl stearate, about 5% by weight of mineral oil petrolatum and about 54% by weight of water.
43. The composition, as claimed in clause 42, characterized in that said emulsion composition has a pH of about 5.5.
44. The composition, as claimed in clause 21, characterized in that it comprises about 10% by weight of lanolin, about 5% by weight of soy sterol, about 5% by weight of glycerin, about 10% by weight. weight of emulsifying wax NF, around 5% by weight of petrolatum or mineral oil and about 60% by weight of water.
45. The composition, as claimed in clause 44, characterized in that said emulsion composition has a pH of about 5.5.
46. The composition, as claimed in clause 21, characterized in that it comprises about 15% by weight of cottonseed oil, about 15% by weight of sterol esters, about 10% by weight of propylene glycol, around of 15% by weight propylene glycol oleate SE, around 10% by weight of petrolatum or mineral oil and around 45% by weight of water.
47. The composition, as claimed in clause 46, characterized in that said emulsion composition has a pH of about 5.5.
48. The composition, as claimed in clause 21, characterized in that it comprises about 30% by weight of afternoon primrose oil, about 5% by weight of cholesterol, about 5% by weight of sodium PCA, around of 10% by weight propylene glycol oleate SE, and about 50% by weight of water.
49. The composition, as claimed in clause 48, characterized in that said emulsion composition has a pH of about 5.5.
50. A non-woven cleaning cloth type product that increases the skin barrier having an oil-in-water emulsion composition comprising: from about 0.1 to about 30% by weight of natural fats or oils; from about 0.1 to about 10% by weight of sterol or sterol derivative; from about 0.1 to about 30% by weight of humectant; from about 0.5 to about 20% by weight of an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to about 18; Y from about 45 to about 99.5% by weight of water.
51. The product, as claimed in clause 50, characterized in that said emulsion composition has a pH ranging from about 4 to about 7.
52. The product, as claimed in clause 50, characterized in that said water is a mixture of alcohol and water.
53. The product, as claimed in clause 52, characterized in that said alcohol is less than about 70% by weight of said mixture of alcohol and water.
54. A method for making a nonwoven cleaning cloth type product comprising: (a) providing a nonwoven fabric; (b) applying an oil-in-water emulsion composition comprising a natural fat or oil, a sterol or a sterol derivative, a humectant, and an emulsifying surfactant having a hydrophilic-lipophilic balance range of from about 7 to around 18, to the non-woven material; (c) Cutting said tea into cleansing cloth type products or components from individual product size pieces for cleaning cloth type products.
55. The method, as claimed in clause 54, characterized in that the oil-in-water emulsion composition is absorbed in the product or components of the wiper-type products. SUMMARY A product such as a cleaning cloth or a soft moist cleaning cloth that increases the health of the skin, such as a baby cleaning cloth, an adult cleaning cloth, a hand cleaning cloth, a face cleaning cloth, a cosmetic cleaning cloth, a household cleaning cloth, an industrial cleaning cloth, a cleaning cloth for personal cleaning, cotton balls, cotton-tipped scourers, and the like, can be made by combining the product of cloth wipe or cloth type cleaner with an oil-in-water emulsion composition comprising a natural oil or fat, a sterol or sterol derivative, a humectant, an emulsifying surfactant, and water.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60/130,804 | 1999-04-23 | ||
US09491898 | 2000-01-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01010760A true MXPA01010760A (en) | 2002-06-05 |
Family
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