MXPA01003003A - Inhaler - Google Patents

Inhaler

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Publication number
MXPA01003003A
MXPA01003003A MXPA/A/2001/003003A MXPA01003003A MXPA01003003A MX PA01003003 A MXPA01003003 A MX PA01003003A MX PA01003003 A MXPA01003003 A MX PA01003003A MX PA01003003 A MXPA01003003 A MX PA01003003A
Authority
MX
Mexico
Prior art keywords
release
elastic
securing
medicament
inhaler
Prior art date
Application number
MXPA/A/2001/003003A
Other languages
Spanish (es)
Inventor
Soren Christrup
Anders Geertjensen
Mikael Jorgensen
Hugo Dines Schmidt
Jorgen Rasmussen
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MXPA01003003A publication Critical patent/MXPA01003003A/en

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Abstract

An inhaler for delivering medicament by inhalation, comprising a housing for holding a canister of medicament having a body and a valve stem compressible together to actuate the canister to deliver a dose of medicament from the valve stem, an actuation mechanism for compressing the canister, a cannister re-set mechanism comprising a locking element for locking thecanister in a compressed state and a release member resiliently biassed by the actuation mechanism on compression of the canister to release the locking mechanism to allow reset of the canister. By provision of the locking element for locking the canister in a compressed state, it is possible to ensure re-set does not occur immediately. The release member subsequently releases the locking mechanism to allow re-set of the canister after a proper dose has been delivered. The cannister reset mechanism further comprises a damping element for damping movement of the release member to delay the action of the resilient biassing to release the locking element a predetermined period of time after actuation of the canister.

Description

INHALER TO SUPPLY A MEDICINE The present invention relates to an inhaler for delivering a medicament by means of inhalation, particularly but not exclusively to an inhaler operated by respiration. Inhalers are commonly used to supply a wide range of medications. Inhalers contain a can or can of medicine that is operated by compression to deliver a dose of medication through a mouthpiece. The inhaler can be provided with a drive mechanism for it to compress the can. This mechanism can be one that is triggered by breathing and that is arranged to trigger the can in response to inhalation at the mouthpiece. Typically, a breathing-powered inhaler includes a preload mechanism for loading an elastic loading member, with a driving force for compressing the can and a firing mechanism arranged to hold the elastic loading member against compression of the can and to release, ie release the elastic loading element at the time of inhalation. REF. DO NOT. 127949 Known cans or cans comprise a body having a protruding valve stem, and an internal metering or dosing chamber that receives a dose of the medicament stored in the body of the can. Compression of the valve stem within the body causes the medication in the metering or metering chamber to be supplied from the valve stem as a dose. The valve stem tilts or biases outward to restore the can or can after compression to deliver the next dose of medication. However, if the compression of the can or canister is released too quickly to thereby allow the restoration of the valve stem, then a full dose is not adequately supplied. The present invention aims to ensure the proper delivery of a full dose. According to the present invention there is provided an inhaler for delivering a medicament by inhalation, same comprising: a housing for containing a can or can of medicament having a body and a valve stem compressible together for driving the can or can for supply a dose of medication from the valve stem; a drive mechanism for compressing the can; a can restoration mechanism, which comprises a securing or securing element for securing the can in a compressed state, and a release member elastically inclined by the compression drive mechanism of the can, to thereby release the mechanism from insurance or assurance to allow the restoration of the can. By providing the insurance element to secure the can in a compressed state, it is possible to ensure that the reset does not occur immediately. The releasing member subsequently releases the insurance mechanism to thereby allow re-establishment of the can once an appropriate dose has been delivered. Preferably, the can restoration mechanism further comprises a damping element for damping the movement of the release member, in order to thereby retard the action of the elastic tilt to release the securing element, in a predetermined period of time once that the can is triggered The damping element may comprise a rotor placed in a viscous fluid and driven by the movement of the release member, which is advantageous because it (the damping element) has a minimum measurement for the desired degree of damping. Notwithstanding the above, it is also possible to contemplate other types of damping elements, an expandable foam or a sinuous path for example. Using a damping element to delay the release of the compressed can, it is possible to control the period in which the can is kept compressed. Typically, such period will range between 100 and 5000 milliseconds. It has been found that the use of a damping is advantageous, this being above a mechanical arrangement that has a time delay. A mechanical arrangement must be manufactured with tight tolerances to properly control the delay, and these tolerances tend to decrease their accuracy over time. On the contrary, a damping element can be easily controlled and does not lose its accuracy over time. Advantageously, the latch element is an articulated joint having a secured position to hold the can in a compression state, and the release member fits or fits with the articulated joint to break the articulated joint in a broken position to release the can. An articulated joint is particularly suitable because it can securely secure the can or can in a state of compression and still be easily narrable. The present invention can be suitably applied to a can, wherein the drive mechanism comprises: a preload mechanism for loading an elastic load member with a driving force using a load member coupled to the elastic load member and which can be moved from a first position, in which the elastic loading element relaxes or loosens to a second position in which the elastic loading element is loaded, the elastic loading element is arranged when it is loaded to skew or tipping the compression of the can, and a firing mechanism arranged to hold or hold the elastic loading member against the compression of the can, and to release the elastic loading element to thereby permit compression of the can. In this case, the insurance or securing element can be arranged to secure the load element in its second position to secure the can in its condition compressed after release of the trigger mechanism. Such a structure prevents the insurance or assurance mechanism from interfering with the operation of the drive mechanism to deliver a dose. Conveniently, the release member is biased or biased elastically by means of a spiral spring, which spirals encircle the load member. It is desirable that the preload mechanism also comprises a lever that fits or fits with the can, inclined by the elastic load element when it is loaded to compress the can, the trigger mechanism that fits with the can in turn fits or fits with the lever for holding and releasing the stored driving force, when the release member is biased or resiliently biased by a spring biasing element acting between the engagement of the can or can and the member and the release member. As the member that fits with the can itself compresses the can, this prevents movement of the release member before the can is understood and thereby reduces the possibility of premature reestablishment by the can or can .
BRIEF DESCRIPTION OF THE FIGURES To enable a better understanding, an inhaler representing the present invention is now described, by way of a non-limiting example, taking as reference the accompanying drawings, drawings in which: Figure 1 is a front view of the inhaler held by one hand; Figure 2 is a side view of the inhaler; Figure 2A is a view of the inhaler without the closure element fixed; Figure 3 is a side view of the inhaler with a portion of the lower housing being removed; Figure 4 is a side view with a portion of the upper housing of the inhaler with a can being removed; Figure 5 is a side view of an alternative form of collar for connecting the closure element to the can; Figure 6 is a cross-sectional view taken along line VI-VI in Figure 5; Figure 7 is a side view of the mounting arrangement of the can and drive mechanism; Figure 8 is a view of the rear and side of the drive mechanism; Figure 9 is a view of the opposite rear and side of Figure 8 of the drive mechanism; Figure 10 is a front view of the arrangement for loading the drive mechanism; Figure 11 is a side view of an alternative form of button arrangement for loading the drive mechanism; Figure 12 is a view of certain parts of the drive mechanism from the front and side; Figures 13 to 16 are schematic views of the drive mechanism illustrating the respective states over a complete cycle of operation; and Figure 17 is a view of the electronic timekeeper or timer circuit.
Figures 1 and 2 illustrate an inhaler 1 representing the present invention, showing respectively the front view of the inhaler 1 held in the hand of a user, and a side view of the inhaler. The inhaler has a housing 2, which comprises an upper housing portion 3, and a lower housing portion 4 which meet coupling.
The portions 3 and 4 of the upper and lower housings have external walls that are hollowed out to define a space in which a medicament can 5 is accommodated, and a driving mechanism 6 operable to drive the can or can 5 Give a dose of medicine. The upper housing portion 3 has the opposite side walls 7 joined by a front and flat wall 8, a curved rear wall 9 and a wall 10 of the upper part. The portion 3 of the lower housing has the opposite side walls 11 which fit or fit flush with the side walls 7 of the portion 3 of the upper housing, and a curved rear wall 12 which fits or adjusts flush with the rear wall 9. of the portion 3 of the upper housing. The rear walls 12 and 9 together form a curved surface that can be comfortably grasped in the palm of a user's hand as illustrated in Figure 1. A nozzle 13 exits from the portion 4 of the lower housing, and this is with the aid of a lid 14 hingedly mounted to the member 4 of the openable lower housing as illustrated in Figure 2.
The front part of the member 4 of the lower housing between the side walls 11 is open to define a vent on the external surface of the housing 2, adjacent to the nozzle 13 between the portions 3 and 4 of the upper and lower housings. The vent 15 is closed by a closing element 16 which fits or adjusts flush with the front wall 8 of the portion 3 of the upper housing to form part of the external wall of the housing 2. The upper and lower housing members are coupled by a coupling 17 which allows the lower housing member 4 to run or slide as illustrated in Figure 3. The can 5 fits or fits into the portion 3 of the upper housing, and can be slidably removed for its replacement as shown in Figure 4. The can 5 comprises a generally cylindrical body 18, and the stem 19 of a valve that can be compressed together to deliver a dose of medicament from the valve stem 19. The can is of a known type, which includes a metering or measuring chamber that captures a defined volume of medicament from body 18 of can 5, whose volume of medicament is it supplies as a metered dose from the valve stem 19 in compression of the valve stem 19 in relation to the body 18. The valve stem 19 tilts a little outwardly for restoration of the can 5 after compression, for Fill the measuring or dosing chamber like this. The stem 19 of the valve is received in a part or block 20 of the nozzle which is arranged to direct a dose of medicament supplied from the valve stem 19 of the inhaler 1 through the nozzle 13. The closure element 16 is connects to the can 5 by a collar 21 fixed around a neck portion 22 of the body 18 of the can. The collar 21 is permanently fixed to the closure element 16 and can be integral with it. The collar 21 is limited by the portion 22 embraced by the neck of the can 5, such that the closing element 16 is removed and replaced together with the can 5 as illustrated in Figure 4. The can 5 and the collar 21 has a small degree of relative movement along the axis of the can 5. This allows the actuation of the can by compression of the can body 18 towards the valve stem 19, when the rod 19 is fixed in relation to inhaler 1 in block 20 of the mouthpiece, and the collar 21 is also fixed by the closing element 16 which fits as part of the housing 2 of the inhaler 1. Figures 5 and 6 respectively illustrate a side view and cross-sectional view as well as an alternative collar 23 for connecting the closure 16 to the can 5. The collar 23 includes a cylindrical portion 24 held in the portion 22 embraced by the neck, of the body 18 of the can by the projection 25, formed this in the cylindrical portion 24 by a cut-out 26 in the form of U. The cylindrical portion 24 has an extension 27 that extends beyond the body 18 of the can to protect the valve stem 19. The extension 27 has a reduced diameter in relation to the rest of the cylindrical portion 24 of the collar 23. Both collars 21 and 23 are formed with a weak portion, constituted by two rupture lines 28 placed on the opposite sides of the collars 21 or 23 and arranged to be broken, preferably from the remainder of the collar 21 or 23 at the time of applying a force to separate the closing element 16 from the can 5. Once the rupture lines 28 have been broken or at least have been deformed to allow the removal of the can 5, it is impossible to connect the collar 21 or 23 to a different can. The external surface of the closure element 16 carries a sign indicating which type of medicament is contained in the can 5 to which the closure element 16 is connected. The indication can be printed information, a recorded or marked form or it can be the color of the closing element 16. An inlet opening 29 is formed in the portion 3 of the upper housing, in particular in its upper wall 10 and front wall 8. The external walls of the housing defined by the upper and lower portions 3 and 4, and the closure element 16 seal together to define a closed space constituting an air flow path extending from the nozzle 13 through the housing 2 to the inlet opening 29. Inhalation in the nozzle 13 pulls air from the opening inlet 29 to the air flow path around the can 5 and the drive mechanism 6 included in the housing 2. The drive mechanism 6 (described in more detail below) lante) has a trigger positioned in the portion 4 of the upper housing which, in response to a flow through the air flow path, triggers the drive mechanism 6 to drive the can 5.
If a can without a closure element connected to it were inserted into the housing 2, then the vent 15 would remain open as illustrated in Figure 2A. Accordingly, when a user inhales in the nozzle 13, the resistance to flow through the vent 15 will be much less than the flow resistance of the remainder of the air flow path above the vent 15 from the inlet opening. 29. In accordance with the foregoing, the vent 15 will vent most of the flow through the nozzle, thereby reducing flow in the remainder of the airflow path in the upper housing portion from beginning to end. . The placement of the vent 15 in the air flow path inside the housing 2 between the nozzle 13 and the trigger reduces the air flow through the trigger. The vent 15 is positioned and sized in such a way that the air flow in the trigger is reduced below the threshold needed to operate the trigger, and therefore prevents the operation of the drive mechanism 6. To assist in the assurance that the vent sufficiently vent the flow, the vent 15 is provided with a larger opening area and thereby a lower resistance to flow than the inlet opening 29. The vent 15 is dimensioned such that the drive mechanism is not operated in the flow through the nozzle 13 at a level that is above the maximum expected inhalation, for example in an inhalation of at least eight times a standard inhalation flow rate. The trigger mechanism for the drive mechanism 6 was designed taking into account the flow generated by a standard inhalation, selected by the designer. Figures 7 to 9 illustrate the drive mechanism 6 for driving the can 5 to deliver a dose of medicament. The elements illustrated in Figures 7 to 9 are accommodated in the housing 2, but these are illustrated separately for clarity purposes. The can 5 is held with its valve stem 19 in a nozzle block 20 'connected to the nozzle 13, both fixed relative to the portion 4 of the lower housing. A nozzle block 20 'has a structural shape slightly different from that of the nozzle block 20 illustrated in Figures 3 and 4 but this performs the same function. The body 18 of the can 5 is supported by a guide block 30, fixed to the portion 3 of the upper housing and having a curved inner surface that fits the cylindrical surface of the can body 18 to allow axial movement of the body 18 of the can within the housing 2. The actuating mechanism 6 operates to compress the body 18 of the can or can relative to the valve stem 19, held in the nozzle block 20 to deliver a dose of medicament. The structure of the drive mechanism 6 is as follows. The actuating mechanism 6 includes a preload mechanism for loading an elastic load element, in the form of a spiral loading spring 31. The preload mechanism includes a load member constituted by an arrow 32, surrounded by the spirals of the loading spring 31. The arrow extends, and can move in a direction parallel to the cylindrical axis 80 of the body 18 of the can or can. The arrow 32 of the load member has an enlarged head 33. As illustrated in Figure 1, the two buttons 34a and 34b, which constitute contact members to be manually depressed, are mounted opposite each other on the side walls. of the portion 3 of the upper housing, or on either of the two sides of the axis 80 of the can 5, fastened in the housing 2. The buttons 34 can be manually depressed in a direction substantially perpendicular to the axis 80 of the can 5, which makes them easy to grip and move by means of a finger and thumb, as can be seen in figure 1. The buttons 34 load the load member 32 and the loading spring 31 through the arrangement shown in Figure 10 comprising the two torsion springs 35a and 35b fixed inside the upper housing portion. The torsion springs 35a and 35b engage the enlarged head 33 of the load member 32 and one of the respective buttons 34 to convert the lateral force applied to the buttons 34, at a downward force, along the axis of the arrow 32 of the load member. In figure 11 there is illustrated an alternative means for converting the lateral force applied to the buttons 34. This means consists of a double articulated joint 36, fixed at its upper end 37 to the portion 3 of the upper housing, fixed at its lower end 38 at the enlarged head 33 of the load member 32, and fixed at its intermediate links 39a and 39b to the respective buttons 34a and 34b. The preload mechanism also includes a lever 40 that rotates relative to the housing, about a pivot or stump 41. The lever 40 has a flat portion 42 that fits the can, portion that contacts the the body 18 of the can adjacent the pivot or stump 41 with the pair of arms 43 and 44 extending from there. An arm 43 is engaged by the loading spring 31 in such a way that the loading spring 31, when it is loaded, compressively tilts the can through the lever 40 coupled to the can 5 by fitting the can with the portion 42. As the loading spring 31 moves further away from the pivot or stump 41 than the engagement of the portion 42 with the can, this provides a leverage between the charged driving force and the force applied to the can 5. The arm 43 it has a hole through which the arrow 32 of the loading member extends. The other arm 44 of the lever 43 has a similar hole through which an additional arrow 78 extends to prevent lateral movement of the lever 40. The drive mechanism further includes a trigger mechanism for holding the lever 40 against compression of the can under the inclination of the spring 31, and to release the lever 40 in response to inhalation in the nozzle. The trigger mechanism is constructed as follows. The firing mechanism comprises a first articulated joint 45 having two links or couplings 46 and 47 rotatably connected to each other by means of a pivot or center journal 50. The upper link 46 is pivotally connected to both arms 43 and 44 of the lever 40 by a pivot or stump 48. The lower link or link 47 is rotatably connected to the portion 3 of the upper housing by a pivot or stump 49. According to the above, the first articulated joint 45 has a secured position illustrated in Figures 7 to 9 in which it holds the lever 40 against the compression of the can 5. In the secured position of the first articulated joint 45, the pivot or central stump 50 is substantially aligned with the journals 48 and 49 at the ends of the links 46 and 47. As the first articulated joint 45 is connected to the lever in a position that is further away from the pivot or stump 41 then the can engages with the portion 42, this provides a leverage between the securing force provided by the first articulated joint and the force applied to the can 5. This leverage increases the securing and firing action of the firing mechanism. The firing mechanism further includes a second articulated joint 51 comprising two links or couplings 52 and 53 connected by a pivot or stump central 54. A link or coupling 57 of the second articulated joint 51 is rotatably connected to the portion 3 of the upper housing by a pivot or trunnion 55, and extends laterally such that this constitutes a moving vane. by an air flow on top of it. The firing vane 52 has a counterweight portion 79 (shown only in Figure 7) attached to the side opposite the pivot or trunnion 55 from the laterally extending surface. The counterweight swings the firing vane in such a way that its center of mass is placed on the axis of the pivot or stump 55. The other link or coupling 53 of the second articulated joint 51 extends from the firing palette 52 between the arms 43 , 44 of the lever 40 to the upper link or coupling 46 of the first articulated joint 45 where it is rotatably connected by a pivot or stump 56. Accordingly, the second articulated joint 51 has a secured position illustrated in FIG. 7 to 9. In the secured position of the second articulated joint, the central journal 54 is substantially aligned with the pins 55 and 56 and the ends of the links 52 and 53.
The drive mechanism 6 further includes a reset mechanism which is constructed as follows. The restoration mechanism employs a locking or securing element constituted by a third articulated joint 57 comprising a link or upper coupling 58 and a lower link or coupling 59 which are connected together in a rotatable manner by means of a pivot or central stump 60. The link or upper coupling 58 is rotatably connected to the portion 3 of the upper housing by the pivot or trunnion 49 in common with the first articulated joint 45. The lower link or coupling 59 is rotatably connected to the arrow 32 of the load member by means of a pivot or stump 61. The third articulated joint 57 has a secured position illustrated in Figures 7 and 9, in which it holds the arrow 32 of the load member in its loaded position as illustrated in Figure 7. In the secured or secured position of the third articulated joint 57, the central pivot or stub 60 is aligned with the pivots or stubs 48 and 61 at the The end of the links 58 and 59. The third articulated joint 57 also tilts or biases in its secured position by means of a tilt spring 67 connected to the portion 3 of the upper housing. Consequently, the The third articulated joint constitutes an insurance or securing element that holds the can in a compressed state by means of the spring 31 and the lever 40, after the complete movement of the lever 40 to compress the can 5. The restoration mechanism further includes a member of release 62, mounted to the arrow 32 of the load member, the latter having an opening through which the arrow 32 extends. The release member 62 can be moved relative to the arrow 32 between the limits defined by a pin or key 63 exiting from arrow 32 fitting into a rail 64 formed in release member 62. A time-keeping spring or time-keeper 65, whose coils surround arrow 32, is connected between arm 43 of lever 40 and member Release 62. The time-keeping spring or time-keeper 65 is in a relaxed state in Figure 7, and the tilting of the release member 62 is provided when the a loaded by the movement of the lever 40 to compress the can 5. A projection 66 extends from the release member 62 (as best seen in the partial view of figure 12) to fit the link or lower coupling 59 of the third articulated joint 57 when the release member 62 moves downwardly of the arrow 32. Such arrangement of the projection 56 with the third joint articulated 57 moves the articulated joint 57 against the inclination spring 67 to break or detach the third articulated joint 57 whereby the locking or securing effect of the third articulated joint 57 is released. The arrow 32 is tilted or directed upwards by the reset spring 68 acting between the arrow 32 and the portion 3 of the upper housing to move the arrow 32 upwardly once the third articulated joint 57 is broken. The downward movement by the release member 62 is damped by an element of damping 69 consisting of a stator 70 fixed to the portion 3 of the upper housing and a rotor 71 that can rotate through a viscous fluid provided between the rotor 71 and the stator 70. The rotor 71 is driven by a toothed rack 72 connected to the release member 62. The operation of the drive mechanism 6 will now be described with reference to figures 13 to 16 which illustrate the various parts of the drive mechanism 6, in a schematic form for easy understanding.
Figure 13 illustrates the neutral state, in which the arrow 32 of the load member is in its uppermost position, in such a way that the loading spring 31 relaxes. In this state, the first and second articulated joints 45 and 51 are both in their secured positions. The time-keeping spring or time-keeper 65 and the reset spring 68 are relaxed. Once the buttons 34 are depressed, the arrow 32 of the load member moves downward to a second position illustrated in Figure 14, loading the loading spring 31 whereby the lever 40 is tilted toward the understanding of the can 5. However, the first articulated joint 45 is in its secured position where it holds the lever 40 against the compression of the can 5. The first articulated joint 45 is held in its own position secured by means of the second articulated joint 51 that is in its secured position. The downward movement by the arrow 32 of the load member also loads the reset spring 68, and places the third articulated joint 57 in its secured position where it is held by the spring 67. In this loaded state illustrated in FIG. Figure 14, the inhaler 1 is charged and ready to deliver a dose of medication. The inhalation of the user in the nozzle 13 generates an air flow through the path for air flow, defined inside the housing 2 from the inner opening 29 to the nozzle 13. This air flow acts on the trigger palette 55, of the second articulated joint 51 causing it to move upwards due to the pressure drop created by the flow inside the housing 2, up to the position illustrated in figure 15, where the second articulated joint breaks or To stop. This breaks or separates the first articulated joint 45 in its broken position illustrated in Figure 15 which releases the lever 40 and allows it to compress the can 5 under the inclination of the loading spring 31. During compression of the cans, the arrow 32 remains secured in position by the third articulated joint 57. This causes the can to be held in its compressed state by the arrow 32 acting through the spring 31 and the lever 40, the spring force of the spring 31 greatly exceeding the inclination of the spring. internal restoration by the can 5.
However, the movement of the lever 40 loads the time-keeping spring or time-keeper 65 which accordingly tilts the release member 62 downwards. The movement of the release member 62 is delayed by the damping action of the damping element 69. The projection 66 of the release element 62 engages with the third joint 57, after a predetermined period of time after the actuation of the can 5. This time is determined by the resistance of the time-keeping spring or time-keeper 65, and by the damping properties of the damping element 69 and is at least 100 or 200 milliseconds, and up to 1000 or 5000 milliseconds to allow this way that the full dose of medicament is delivered from the can 5. Such a fit ruptures or separates the third articulated joint 57 in its broken or separated position as illustrated in Figure 16. Subsequently, the reset spring 68 moves the arrow 32 of the limb member. load up to the neutral position illustrated in figure 13. At the same time, arrow 32 lifts the liber member ation 62, itself still damped by the damper element 69 in such a way that the restoration movement is damped.
The release of the arrow 32 causes the spring 31 to raise the lever 40, which has two effects; in the first place, this allows the can to reestablish itself; secondly, this causes the first and second articulated joints 45 and 51 to be straightened, returning them to their secured position in the neutral position of the drive mechanism illustrated in Figure 13. The loading spring 31 and the time-keeping spring or time-keeper 65 are preloaded and do not work against the resetting movement, in such a manner that the reset spring 68 only has to overcome the friction and the weight of the component. Buttons 34a and 34b exit the inhaler when the drive is in its relaxed state as shown in FIG. 1, and are pressed to a position flush with the side walls 8 of the portion 3 of the upper housing. Accordingly, the distance between the ends of the buttons before being depressed is less than the maximum length of the inhaler 1 in the direction parallel to the axis 80 of the can 5, and less than the full length of the can 5 that includes body 18 and valve stem 19. In addition, the total distance over which the two buttons 34 move in relation to each other, is higher that the distance at which the body 18 and the stem 19 of the valve of the can 5 are relatively compressed. This is achieved by the leverage obtained by the loading spring 31 which engages the lever 40 at a point further away from the pivot or stump 41 than the can that engages with the portion 42. The actual flow recommended to properly deliver a medicament will depend on the form of operation of the medication, the position in which it must be deposited in the mouth, the lungs of the user and the manner of delivery in medicine. Some medications are inhaled like a fine vapor that is completely transported to the lungs, while others are inhaled like a jet of liquid deposited in the person's mouth. These different types of medicines require different types of inhalation, and therefore different inhalation flows and different actions by the user. It is possible to adapt each of a number of different inhalers to be used with a number of different types of medications, providing each inhaler with a ventilator with different configuration and providing different configurations of closure elements that match or conform to a single type of inhaler. . By example, a possible different configuration is illustrated by the dotted line in figure 1. Thus, the can with different closure elements configured differently, is intended to be used exclusively with the inhaler having a chord ventilated. The different configurations can prevent a closure element from being adapted in an inhaler, from the inhaler having a corresponding ventilation. Alternatively, the closure element may fail to close by closing the ventilator of an inhaler having a ventilator configured differently, so that the remaining aperture ventilates the flow sufficiently to prevent the operation of the firing mechanism. It is noted that in relation to this date, the best method known to the applicant to carry out the aforementioned invention, is that which is clear from the manufacture of the objects or products to which it refers.

Claims (9)

CLAIMS Having described the invention as above, the content of the following claims is claimed as property:
1. An inhaler for delivering a medicament by inhalation, characterized in that it comprises: a housing for holding a can or can of medicament having a body and a valve stem, which can be compressed together to operate the can so as to supply a dose of medication from the valve stem; a drive mechanism for compressing the can; a can restoration mechanism comprising a securing element for securing the can in a compressed state, and a release member elastically inclined by the driving mechanism on the compression of the can, to thereby release the securing mechanism to allow the restoration of the can.
2. An inhaler according to claim 1, characterized in that the mechanism that restores the can it comprises a damping element for damping the movement of the release member to retard the action of the elastic inclination, this in order to release the securing element in a predetermined period of time once the can is actuated.
3. An inhaler according to claim 2, characterized in that the damping element comprises a rotor placed in a viscous fluid and is driven by the movement of the release member.
4. An inhaler according to the claim 2 or 3, characterized in that the predetermined time period ranges between 100 and 5000 milliseconds. An inhaler according to one of the preceding claims, characterized in that the securing element is an articulated joint having a secured position for holding the can in a compressed state, and the release member engages with the articulated joint to break or separate the articulated joint in a broken or separated position in order to release the can. 6. An inhaler according to one of the preceding claims, characterized in that the driving mechanism comprises: a preloading mechanism for loading an elastic load element, with a driving force using a load member coupled to the elastic load member, and which can be moved from a first position where the elastic load element is relaxed, to a second position where the elastic loading element is loaded, the elastic loading element is arranged when it is loaded to tilt or bias the compression of the can; and a firing mechanism arranged to hold or hold the elastic loading member against compression of the can, and to release the elastic loading element to allow compression of the can. An inhaler according to claim 6, characterized in that the securing element is arranged to secure the loading member in its second position, to secure the can in its compressed state after release of the firing mechanism. 8. An inhaler according to claim 6 or 7, characterized in that the preload mechanism further comprises a member for fitting with the can, inclined by the elastic loading element when it is loaded in order to compress the can, mechanism of shot that fits with the member that fits with the can to maintain and release the stored driving force, wherein the release member is elastically inclined by an elastic tilting member acting between the member that engages the can and the canister member. release. 9. An inhaler according to the claim 8, characterized in that the member with which the can fits is a lever that can rotate, inclined by the elastic loading element in a position that moves further away from the pivot or stump of the lever than the portion of the lever that fits the can. SUMMARY OF THE INVENTION An inhaler for delivering a medicament by inhalation, same comprising a housing for holding a can or can of medicament having a body and a valve stem that can be compressed together to operate the can, in order to deliver a dose of medicament from the stem of the valve, a drive mechanism for compressing the can, a can reset mechanism, a mechanism comprising a securing element for securing the can in a compressed state, and a release member elastically inclined by the driving mechanism in the compression of the can to release the securing mechanism in order to allow the restoration of the can. By providing the securing element to secure the can in a compressed state, it is possible to ensure that the reset does not occur immediately. The releasing member subsequently releases the securing mechanism to allow re-establishment of the can after an adequate dose of medicament has been delivered. The restoration mechanism of the can also comprises a damping element for dampening the movement of the release member to retard the action of the elastic inclination, so as to release the securing element in a predetermined period of time after the actuation of the can.
MXPA/A/2001/003003A 1998-09-24 2001-03-22 Inhaler MXPA01003003A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PAPA199801207 1998-09-24

Publications (1)

Publication Number Publication Date
MXPA01003003A true MXPA01003003A (en) 2001-12-13

Family

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