MXPA00007634A - Nuevos compuestos de triazol (4,5-d) pirimidina. - Google Patents

Nuevos compuestos de triazol (4,5-d) pirimidina.

Info

Publication number
MXPA00007634A
MXPA00007634A MXPA00007634A MXPA00007634A MXPA00007634A MX PA00007634 A MXPA00007634 A MX PA00007634A MX PA00007634 A MXPA00007634 A MX PA00007634A MX PA00007634 A MXPA00007634 A MX PA00007634A MX PA00007634 A MXPA00007634 A MX PA00007634A
Authority
MX
Mexico
Prior art keywords
novel triazolo
triazolo
novel
Prior art date
Application number
MXPA00007634A
Other languages
English (en)
Inventor
Brian Springthorpe
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800458A external-priority patent/SE9800458D0/xx
Priority claimed from SE9803669A external-priority patent/SE9803669D0/xx
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of MXPA00007634A publication Critical patent/MXPA00007634A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
MXPA00007634A 1998-02-17 1999-02-05 Nuevos compuestos de triazol (4,5-d) pirimidina. MXPA00007634A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9800458A SE9800458D0 (sv) 1998-02-17 1998-02-17 Novel compounds
SE9803669A SE9803669D0 (sv) 1998-10-26 1998-10-26 Novel compounds
PCT/SE1999/000154 WO1999041254A1 (en) 1998-02-17 1999-02-05 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS

Publications (1)

Publication Number Publication Date
MXPA00007634A true MXPA00007634A (es) 2003-09-10

Family

ID=26663214

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA00007634A MXPA00007634A (es) 1998-02-17 1999-02-05 Nuevos compuestos de triazol (4,5-d) pirimidina.

Country Status (21)

Country Link
US (1) US6369064B1 (es)
EP (1) EP1056749B1 (es)
JP (1) JP2002503663A (es)
KR (1) KR20010078696A (es)
CN (1) CN1291193A (es)
AR (1) AR015515A1 (es)
AT (1) ATE232866T1 (es)
AU (1) AU2650099A (es)
BR (1) BR9907934A (es)
CA (1) CA2316264A1 (es)
DE (1) DE69905451T2 (es)
HU (1) HUP0100328A3 (es)
ID (1) ID27127A (es)
IL (1) IL137812A0 (es)
MX (1) MXPA00007634A (es)
NO (1) NO20004089L (es)
NZ (1) NZ505250A (es)
PL (1) PL342430A1 (es)
SK (1) SK12242000A3 (es)
TR (1) TR200002380T2 (es)
WO (1) WO1999041254A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702773D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9904129D0 (sv) * 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
GB0013488D0 (en) 2000-06-02 2000-07-26 Astrazeneca Ab Chemical compound
TWI290549B (en) * 2000-06-02 2007-12-01 Astrazeneca Ab Process for the preparation of cyclopropyl carboxylic acid ester and derivatives
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
GB0219746D0 (en) * 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
US7504497B2 (en) 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7335648B2 (en) 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
US7368438B2 (en) 2003-10-21 2008-05-06 Inspire Pharmaceuticals, Inc. Non-nucleotide compositions and method for inhibiting platelet aggregation
US7749981B2 (en) * 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
US7932376B2 (en) 2005-05-05 2011-04-26 Inspire Pharmaceuticals, Inc. Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation
WO2007020935A1 (ja) * 2005-08-17 2007-02-22 Ono Pharmaceutical Co., Ltd. P2y12受容体および/またはp2y14受容体ブロッカーを含有してなる疼痛治療剤
US7566722B2 (en) * 2006-10-31 2009-07-28 Janssen Pharmaceutica, N.V. Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists
ES2558843T3 (es) * 2008-09-09 2016-02-09 Astrazeneca Ab Procedimiento para preparar [1S-[1-alfa,2-alfa,3-beta(1S*,2R*),5-beta]]-3-[7-[2-(3,4-difluorofenil)-ciclopropilamino]-5-(propiltio)-3H-1,2,3-triazolo[4,5-d]pirimidin-3-il]-5-(2-hidroxietoxi)ciclopentano-1,2-diol y a sus productos intermedios
WO2015027431A1 (en) 2013-08-29 2015-03-05 Merck Sharp & Dohme Corp. 2,2-difluorodioxolo a2a receptor antagonists
WO2015162630A1 (en) * 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
US9840481B2 (en) 2016-03-22 2017-12-12 Merck Sharp & Dohme Corp. Allosteric modulators of nicotinic acetylcholine receptors
CN111116592A (zh) * 2019-11-27 2020-05-08 杭州沧海帆医药科技有限公司 嘧啶并三氮唑类化合物及其医药用途
CN112876485A (zh) * 2021-01-25 2021-06-01 郭丽伟 一种用于治疗子宫平滑肌高频率强直性收缩相关疾病的化合物
WO2023091768A1 (en) * 2021-11-22 2023-05-25 Purdue Research Foundation Cell-potent bisubstrate inhibitors for nicotinamide n-methyltransferase (nnmt) and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742064A (en) 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
GB8826205D0 (en) 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
EP0840740B1 (en) * 1995-07-11 2002-05-02 AstraZeneca AB New inhibitors of platelet aggregation
WO1998028300A1 (en) 1996-12-20 1998-07-02 Astra Pharmaceuticals Ltd. Triazolo[4,5-d]pyrimidinyl derivatives and their use as medicaments
SE9702774D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9702772D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
DE69905451D1 (de) 2003-03-27
JP2002503663A (ja) 2002-02-05
NZ505250A (en) 2002-10-25
ATE232866T1 (de) 2003-03-15
NO20004089L (no) 2000-10-16
NO20004089D0 (no) 2000-08-16
EP1056749B1 (en) 2003-02-19
WO1999041254A1 (en) 1999-08-19
CN1291193A (zh) 2001-04-11
HUP0100328A3 (en) 2003-04-28
HUP0100328A2 (hu) 2001-09-28
EP1056749A1 (en) 2000-12-06
TR200002380T2 (tr) 2001-03-21
AR015515A1 (es) 2001-05-02
AU2650099A (en) 1999-08-30
DE69905451T2 (de) 2003-11-20
BR9907934A (pt) 2000-10-24
CA2316264A1 (en) 1999-08-19
PL342430A1 (en) 2001-06-04
KR20010078696A (ko) 2001-08-21
IL137812A0 (en) 2001-10-31
US6369064B1 (en) 2002-04-09
SK12242000A3 (sk) 2001-03-12
ID27127A (id) 2001-03-01

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