MX9801680A - Derivado de fenil pirimidina opticamente activo como agente analgesico. - Google Patents

Derivado de fenil pirimidina opticamente activo como agente analgesico.

Info

Publication number
MX9801680A
MX9801680A MX9801680A MX9801680A MX9801680A MX 9801680 A MX9801680 A MX 9801680A MX 9801680 A MX9801680 A MX 9801680A MX 9801680 A MX9801680 A MX 9801680A MX 9801680 A MX9801680 A MX 9801680A
Authority
MX
Mexico
Prior art keywords
optically active
analgesic agent
pyrimidine derivative
phenyl pyrimidine
active phenyl
Prior art date
Application number
MX9801680A
Other languages
English (en)
Other versions
MXPA98001680A (es
Inventor
Malcolm Stuart Nobbs
Sandra Jane Rodgers
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MX9801680A publication Critical patent/MX9801680A/es
Publication of MXPA98001680A publication Critical patent/MXPA98001680A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion se refiere a una pirimina de la formula (I): y a las sales de adicion ácida de la misma aceptables farmacéuticamente, que son utiles como analgésicos, como anticonvulsivos o en el tratamiento del síndrome del intestino irritable o del desorden bipolar.
MXPA/A/1998/001680A 1995-09-05 1998-03-02 Derivado de fenil pirimidina opticamente activo como agente analgesico MXPA98001680A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9518027.9 1995-09-05
GBGB9518027.9A GB9518027D0 (en) 1995-09-05 1995-09-05 Pharmacologically active compound
PCT/EP1996/003856 WO1997009317A2 (en) 1995-09-05 1996-09-03 Optically active phenyl pyrimidine derivative as analgesic agent

Publications (2)

Publication Number Publication Date
MX9801680A true MX9801680A (es) 1998-05-31
MXPA98001680A MXPA98001680A (es) 1998-10-23

Family

ID=

Also Published As

Publication number Publication date
US6124308A (en) 2000-09-26
AP640A (en) 1998-04-14
BG102342A (en) 1998-09-30
AU6986596A (en) 1997-03-27
ID17274A (id) 1997-12-18
AP9600857A0 (en) 1996-10-31
HUP9901260A2 (hu) 1999-09-28
SK28598A3 (en) 1998-09-09
CN1200729A (zh) 1998-12-02
NO980923D0 (no) 1998-03-04
CO4750651A1 (es) 1999-03-31
HUP9901260A3 (en) 2001-04-28
ZA967466B (en) 1998-04-06
WO1997009317A2 (en) 1997-03-13
PL325329A1 (en) 1998-07-20
AR004192A1 (es) 1998-11-04
NZ318390A (en) 1999-02-25
BR9610388A (pt) 1999-07-06
TR199800386T1 (xx) 1998-05-21
EP0879230B1 (en) 2001-07-25
GB9518027D0 (en) 1995-11-08
IL123414A0 (en) 1998-09-24
AU710091B2 (en) 1999-09-16
HRP960399A2 (en) 1998-04-30
TW367326B (en) 1999-08-21
ATE203523T1 (de) 2001-08-15
CA2230362A1 (en) 1997-03-13
EA000695B1 (ru) 2000-02-28
DE69614150T2 (de) 2001-11-22
JPH11512108A (ja) 1999-10-19
DE69614150D1 (de) 2001-08-30
YU49796A (sh) 1999-07-28
ES2160834T3 (es) 2001-11-16
CZ65598A3 (cs) 1998-07-15
BG65102B1 (bg) 2007-02-28
IS4673A (is) 1998-02-23
NO980923L (no) 1998-05-04
EP0879230A2 (en) 1998-11-25
WO1997009317A3 (en) 1997-04-03
KR19990044397A (ko) 1999-06-25
EA199800189A1 (ru) 1998-10-29

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