MX9709690A - Microdispersiones continuas de fluoroquimicos para el suministro de agentes farmaceuticos. - Google Patents

Microdispersiones continuas de fluoroquimicos para el suministro de agentes farmaceuticos.

Info

Publication number
MX9709690A
MX9709690A MX9709690A MX9709690A MX9709690A MX 9709690 A MX9709690 A MX 9709690A MX 9709690 A MX9709690 A MX 9709690A MX 9709690 A MX9709690 A MX 9709690A MX 9709690 A MX9709690 A MX 9709690A
Authority
MX
Mexico
Prior art keywords
pharmaceutical
pharmaceutical composition
delivery
pharmaceutical agents
microdispersion
Prior art date
Application number
MX9709690A
Other languages
English (en)
Other versions
MXPA97009690A (es
Inventor
Leo A Trevino
Luis A Dellamary
Thomas E Tarara
Jeffry G Weers
Helen M Ranney
Original Assignee
Alliance Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alliance Pharma filed Critical Alliance Pharma
Publication of MX9709690A publication Critical patent/MX9709690A/es
Publication of MXPA97009690A publication Critical patent/MXPA97009690A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un método para preparar una microdispersion farmacéutica que exhiba biodisponibilidad mejorada, que incluye las siguientes etapas: proporcionar una composicion farmacéutica termodinámicamente estable que comprende al menos un agente farmacéutico incorporado en un portador líquido fisiologicamente aceptable, el portador líquido comprende uno o más solventes lipofílicos, tales como fluoroquímicos, y de preferencia al menos un co-solvente no fluorado, y combinar una composicion farmacéutica estable con una cantidad de al menos un diluyente miscible suficiente para iniciar la separacion de fase del agente farmacéutico a partir de la composicion farmacéutica, en donde se forma una microdispersion de la composicion farmacéutica. También se revelan composiciones farmacéuticas microdispersas, y herramientas para formar dichas composiciones.
MXPA/A/1997/009690A 1995-06-07 1997-12-05 Microdispersiones continuas de fluoroquimicos para el suministro de agentes farmaceuticos MXPA97009690A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08482176 1995-06-07
US08/482,176 US5667809A (en) 1995-06-07 1995-06-07 Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents

Publications (2)

Publication Number Publication Date
MX9709690A true MX9709690A (es) 1998-03-29
MXPA97009690A MXPA97009690A (es) 1998-10-15

Family

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Also Published As

Publication number Publication date
NO975320D0 (no) 1997-11-19
KR100454377B1 (ko) 2005-08-04
EP0831770A1 (en) 1998-04-01
CN1192135A (zh) 1998-09-02
AU6049496A (en) 1996-12-30
PL323829A1 (en) 1998-04-27
GR3034657T3 (en) 2001-01-31
AU721759B2 (en) 2000-07-13
JPH11506783A (ja) 1999-06-15
DK0831770T3 (da) 2000-12-18
EP0831770B1 (en) 2000-08-16
KR19990022587A (ko) 1999-03-25
CA2222081A1 (en) 1996-12-19
US5667809A (en) 1997-09-16
WO1996040053A1 (en) 1996-12-19
NO975320L (no) 1998-01-27
ES2150674T3 (es) 2000-12-01
ATE195415T1 (de) 2000-09-15
HUP9900872A2 (hu) 1999-08-30
IL122241A0 (en) 1998-04-05
PT831770E (pt) 2000-11-30
DE69609834D1 (de) 2000-09-21
DE69609834T2 (de) 2000-12-21

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