MX9707596A - Benzamidas, el uso de las mismas, composiciones que las contienen, para el tratamiento del transtorno neurodegenerativo, y procedimiento para la preparacion del mismo. - Google Patents
Benzamidas, el uso de las mismas, composiciones que las contienen, para el tratamiento del transtorno neurodegenerativo, y procedimiento para la preparacion del mismo.Info
- Publication number
- MX9707596A MX9707596A MX9707596A MX9707596A MX9707596A MX 9707596 A MX9707596 A MX 9707596A MX 9707596 A MX9707596 A MX 9707596A MX 9707596 A MX9707596 A MX 9707596A MX 9707596 A MX9707596 A MX 9707596A
- Authority
- MX
- Mexico
- Prior art keywords
- benzamides
- neurodegenerative disorder
- disorder treatment
- disclosed
- nhcoch3
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se describen composiciones farmacéuticas que contienen como ingredientes activo un compuesto de la formula (I): en donde R' es un alquilo saturado de 3 a 5 átomos de carbono, cada R es independientemente -NO2, 0 -NH2, o -NHCOCH3, y n es 1 o 2, algunos de estos compuestos siendo nuevos; un procedimiento para su preparacion, así como su uso en la fabricacion de medicamentos para tratar condiciones caracterizadas por pérdida progresiva de la funcion del sistema nervioso central tales como enfermedad de Parkinson y enfermedad de Alzheimer.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41567795A | 1995-04-03 | 1995-04-03 | |
US08/415,847 US5643965A (en) | 1995-04-03 | 1995-04-03 | Aminobenzamide compounds for the treatment of neurodegenerative disorders |
US08/415,694 US5658953A (en) | 1995-04-03 | 1995-04-03 | Pharmaceutical compositions of acetamidobenzamide compounds for neurodegenerative disorders |
US08/415,248 US5659082A (en) | 1995-04-03 | 1995-04-03 | Nitro- and aminobenzamide compounds for neurodegenerative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9707596A true MX9707596A (es) | 1998-06-30 |
Family
ID=27503636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9707596A MX9707596A (es) | 1995-04-03 | 1997-10-02 | Benzamidas, el uso de las mismas, composiciones que las contienen, para el tratamiento del transtorno neurodegenerativo, y procedimiento para la preparacion del mismo. |
Country Status (39)
Country | Link |
---|---|
EP (1) | EP0819113B1 (es) |
JP (1) | JP3479658B2 (es) |
KR (1) | KR100429120B1 (es) |
CN (1) | CN1073552C (es) |
AR (1) | AR002978A1 (es) |
AT (1) | ATE202552T1 (es) |
AU (1) | AU721045B2 (es) |
BG (1) | BG63384B1 (es) |
CA (1) | CA2215166A1 (es) |
CO (1) | CO4700431A1 (es) |
CZ (1) | CZ295852B6 (es) |
DE (1) | DE69613567T2 (es) |
DK (1) | DK0819113T3 (es) |
DZ (1) | DZ2012A1 (es) |
EA (1) | EA002031B1 (es) |
EE (1) | EE03437B1 (es) |
ES (1) | ES2160240T3 (es) |
GR (1) | GR3036466T3 (es) |
HK (1) | HK1016964A1 (es) |
HR (1) | HRP960156B1 (es) |
HU (1) | HUP9801759A3 (es) |
IL (1) | IL117629A (es) |
IS (1) | IS1919B (es) |
MA (1) | MA23837A1 (es) |
MX (1) | MX9707596A (es) |
MY (1) | MY121206A (es) |
NO (1) | NO318441B1 (es) |
NZ (1) | NZ306204A (es) |
PL (1) | PL184121B1 (es) |
PT (1) | PT819113E (es) |
RO (1) | RO116190B1 (es) |
SA (1) | SA96160739B1 (es) |
SI (1) | SI0819113T1 (es) |
SK (1) | SK282900B6 (es) |
TN (1) | TNSN96051A1 (es) |
TR (1) | TR199701114T1 (es) |
TW (1) | TW381073B (es) |
WO (1) | WO1996031462A1 (es) |
YU (1) | YU21096A (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU720578B2 (en) * | 1996-04-17 | 2000-06-08 | Centaur Pharmaceuticals, Inc. | Benzamide treatment of dementia associated with AIDS virus (HIV-1) infection |
AU9646298A (en) | 1997-10-27 | 1999-05-17 | Sumitomo Pharmaceuticals Company, Limited | Amide derivatives |
US6271265B1 (en) | 1998-05-19 | 2001-08-07 | Centaur Pharmaceuticals, Inc. | Amide therapeutics for the treatment of inflammatory bowel disease |
AU4184499A (en) * | 1998-05-19 | 1999-12-06 | Renovis, Inc. | Benzamide therapeutics for the treatment of inflammatory bowel disease |
WO2000064430A1 (fr) * | 1999-04-23 | 2000-11-02 | Sumitomo Pharmaceuticals Co., Ltd. | Inhibiteurs de l'apoptose |
CN101817761B (zh) * | 2010-01-29 | 2014-06-25 | 浙江大学 | 苯甲酸酯类衍生物及制备方法和应用 |
US9206125B2 (en) | 2010-02-10 | 2015-12-08 | Public University Corporation Yokohama City University | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) |
WO2014155184A1 (en) * | 2013-03-28 | 2014-10-02 | Rhenovia Pharma | Treatment for parkinson's disease |
CN115594603A (zh) * | 2022-10-09 | 2023-01-13 | 湖北师范大学(Cn) | 微通道反应器制备n-叔丁基-4-氨基苯甲酰胺的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1069882B (it) * | 1975-12-22 | 1985-03-25 | Mallinckrodt Inc | 3 5 bis acilammino benzammidi particolarmente utili come agenti di contrasto per raffi x e procedimento per la loro preparazione |
JPS5721320A (en) * | 1980-07-11 | 1982-02-04 | Chugai Pharmaceut Co Ltd | Blood sugar level depressing agent |
JPS5867657A (ja) * | 1981-10-15 | 1983-04-22 | Chugai Pharmaceut Co Ltd | ペンズアミド誘導体 |
US5472983A (en) * | 1994-04-14 | 1995-12-05 | Centaur Pharmaceuticals, Inc. | Benzamide-containing pharmaceutical compositions |
-
1996
- 1996-03-24 IL IL11762996A patent/IL117629A/xx active IP Right Grant
- 1996-03-27 DZ DZ960053A patent/DZ2012A1/fr active
- 1996-03-28 TW TW085103754A patent/TW381073B/zh active
- 1996-03-28 AR AR10196396A patent/AR002978A1/es unknown
- 1996-04-01 MA MA24193A patent/MA23837A1/fr unknown
- 1996-04-02 YU YU21096A patent/YU21096A/sh unknown
- 1996-04-02 CO CO96016205A patent/CO4700431A1/es unknown
- 1996-04-03 TN TNTNSN96051A patent/TNSN96051A1/fr unknown
- 1996-04-03 HU HU9801759A patent/HUP9801759A3/hu unknown
- 1996-04-03 JP JP53043896A patent/JP3479658B2/ja not_active Expired - Fee Related
- 1996-04-03 HR HR960156A patent/HRP960156B1/xx not_active IP Right Cessation
- 1996-04-03 CZ CZ19973098A patent/CZ295852B6/cs not_active IP Right Cessation
- 1996-04-03 DK DK96911550T patent/DK0819113T3/da active
- 1996-04-03 MY MYPI96001225A patent/MY121206A/en unknown
- 1996-04-03 EE EE9700235A patent/EE03437B1/xx not_active IP Right Cessation
- 1996-04-03 PT PT96911550T patent/PT819113E/pt unknown
- 1996-04-03 PL PL96322625A patent/PL184121B1/pl not_active IP Right Cessation
- 1996-04-03 SI SI9630313T patent/SI0819113T1/xx unknown
- 1996-04-03 RO RO97-01826A patent/RO116190B1/ro unknown
- 1996-04-03 SK SK1325-97A patent/SK282900B6/sk unknown
- 1996-04-03 NZ NZ306204A patent/NZ306204A/xx unknown
- 1996-04-03 EA EA199700287A patent/EA002031B1/ru not_active IP Right Cessation
- 1996-04-03 TR TR97/01114T patent/TR199701114T1/xx unknown
- 1996-04-03 AT AT96911550T patent/ATE202552T1/de not_active IP Right Cessation
- 1996-04-03 CN CN96193000A patent/CN1073552C/zh not_active Expired - Fee Related
- 1996-04-03 WO PCT/US1996/004538 patent/WO1996031462A1/en active IP Right Grant
- 1996-04-03 EP EP96911550A patent/EP0819113B1/en not_active Expired - Lifetime
- 1996-04-03 DE DE69613567T patent/DE69613567T2/de not_active Expired - Fee Related
- 1996-04-03 KR KR1019970706966A patent/KR100429120B1/ko not_active IP Right Cessation
- 1996-04-03 ES ES96911550T patent/ES2160240T3/es not_active Expired - Lifetime
- 1996-04-03 CA CA002215166A patent/CA2215166A1/en not_active Abandoned
- 1996-04-03 AU AU54404/96A patent/AU721045B2/en not_active Ceased
- 1996-04-15 SA SA96160739A patent/SA96160739B1/ar unknown
-
1997
- 1997-09-25 IS IS4569A patent/IS1919B/is unknown
- 1997-09-29 BG BG101929A patent/BG63384B1/bg unknown
- 1997-10-02 MX MX9707596A patent/MX9707596A/es not_active IP Right Cessation
- 1997-10-02 NO NO19974569A patent/NO318441B1/no unknown
-
1998
- 1998-11-18 HK HK98112098A patent/HK1016964A1/xx not_active IP Right Cessation
-
2001
- 2001-08-30 GR GR20010401321T patent/GR3036466T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
PD | Change of proprietorship |
Owner name: RENOVIS, INC. |
|
MM | Annulment or lapse due to non-payment of fees |