MX9706876A - Pirazolo[3,4-d]pirimidin-4-onas 6-sustituidas y composiciones y metodo para su uso. - Google Patents

Pirazolo[3,4-d]pirimidin-4-onas 6-sustituidas y composiciones y metodo para su uso.

Info

Publication number
MX9706876A
MX9706876A MX9706876A MX9706876A MX9706876A MX 9706876 A MX9706876 A MX 9706876A MX 9706876 A MX9706876 A MX 9706876A MX 9706876 A MX9706876 A MX 9706876A MX 9706876 A MX9706876 A MX 9706876A
Authority
MX
Mexico
Prior art keywords
pyrimidin
methods
substituted pyrazolo
ones
compositions
Prior art date
Application number
MX9706876A
Other languages
English (en)
Other versions
MXPA97006876A (es
Inventor
Edward R Bacon
Sol J Daum
Baldev Singh
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of MX9706876A publication Critical patent/MX9706876A/es
Publication of MXPA97006876A publication Critical patent/MXPA97006876A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivados de pirazolo[3,4-d]pirimidin-4-ona 6-sustituida, composiciones farmacéuticas que los contienen y métodos para a) efectuar la inhibicion c-GMP-fosfodiesterasa, b) tratar la falla del corazon y/o hipertension, c) invertir o reducir la tolerancia inducida por nitrato y d) tratar la angina de pecho, enfermedad del corazon congestionado e infarto al miocardio utilizando los mismos.
MXPA/A/1997/006876A 1995-03-10 1997-09-09 Pirazolo[3,4-d]pirimidin-4-onas 6-sustituidas y composiciones y metodo para su uso MXPA97006876A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/402,268 US5656629A (en) 1995-03-10 1995-03-10 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof
US08402268 1995-03-10

Publications (2)

Publication Number Publication Date
MX9706876A true MX9706876A (es) 1998-06-28
MXPA97006876A MXPA97006876A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
NO974151D0 (no) 1997-09-09
HUP9801336A2 (hu) 1998-10-28
US5656629A (en) 1997-08-12
ZA961947B (en) 1996-10-07
NZ306035A (en) 1999-07-29
CA2211669A1 (en) 1996-09-19
JPH11501923A (ja) 1999-02-16
EP0813527A4 (en) 1998-09-09
WO1996028429A1 (en) 1996-09-19
AU708750B2 (en) 1999-08-12
NO974151L (no) 1997-11-04
CZ280597A3 (cs) 1998-04-15
AU5418896A (en) 1996-10-02
PL322380A1 (en) 1998-01-19
KR19980702891A (ko) 1998-08-05
US5977118A (en) 1999-11-02
EP0813527A1 (en) 1997-12-29
HUP9801336A3 (en) 2000-07-28

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