MX9702357A - Spray-dried microparticles as therapeutic vehicles. - Google Patents
Spray-dried microparticles as therapeutic vehicles.Info
- Publication number
- MX9702357A MX9702357A MX9702357A MX9702357A MX9702357A MX 9702357 A MX9702357 A MX 9702357A MX 9702357 A MX9702357 A MX 9702357A MX 9702357 A MX9702357 A MX 9702357A MX 9702357 A MX9702357 A MX 9702357A
- Authority
- MX
- Mexico
- Prior art keywords
- spray
- dried microparticles
- therapeutic
- agent
- therapeutic vehicles
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002195 soluble material Substances 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
Abstract
Microparticles of a water-soluble material, which are smooth and spherical, and at least 90 percent of which have a mass median particle size of 1 to 10 'mu'm, and which either carry a therapeutic or diagnostic agent or use such an agent as the water-soluble material, can successfully be used in dry powder inhalers to deliver the said agent.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94307126 | 1994-09-29 | ||
EP94307126.6 | 1994-09-29 | ||
PCT/GB1995/002279 WO1996009814A1 (en) | 1994-09-29 | 1995-09-26 | Spray-dried microparticles as therapeutic vehicles |
Publications (2)
Publication Number | Publication Date |
---|---|
MXPA97002357A MXPA97002357A (en) | 1997-06-01 |
MX9702357A true MX9702357A (en) | 1997-06-28 |
Family
ID=8217866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9702357A MX9702357A (en) | 1994-09-29 | 1995-09-26 | Spray-dried microparticles as therapeutic vehicles. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0783298A1 (en) |
JP (1) | JPH10506406A (en) |
KR (1) | KR970705979A (en) |
AU (1) | AU701440B2 (en) |
BR (1) | BR9509171A (en) |
CA (1) | CA2199954A1 (en) |
CZ (1) | CZ92497A3 (en) |
FI (1) | FI971332A (en) |
HU (1) | HUT77373A (en) |
MX (1) | MX9702357A (en) |
NO (1) | NO971438D0 (en) |
NZ (1) | NZ292980A (en) |
PL (1) | PL319600A1 (en) |
RU (1) | RU2147226C1 (en) |
WO (1) | WO1996009814A1 (en) |
ZA (1) | ZA958239B (en) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
US5955108A (en) * | 1994-12-16 | 1999-09-21 | Quadrant Healthcare (Uk) Limited | Cross-linked microparticles and their use as therapeutic vehicles |
GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
GB9606677D0 (en) * | 1996-03-29 | 1996-06-05 | Glaxo Wellcome Inc | Process and device |
GB9607035D0 (en) * | 1996-04-03 | 1996-06-05 | Andaris Ltd | Spray-dried microparticles as therapeutic vehicles |
GB9610341D0 (en) * | 1996-05-17 | 1996-07-24 | Andaris Ltd | Formulation for inhalation |
WO1997044015A1 (en) * | 1996-05-17 | 1997-11-27 | Andaris Limited | Microparticles and their use in wound therapy |
US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
USRE37053E1 (en) | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
US6254854B1 (en) | 1996-05-24 | 2001-07-03 | The Penn Research Foundation | Porous particles for deep lung delivery |
GB9615435D0 (en) * | 1996-07-23 | 1996-09-04 | Andaris Ltd | Spray-dried product and its therapeutic use |
WO1998017318A1 (en) * | 1996-10-19 | 1998-04-30 | Quadrant Healthcare (Uk) Limited | Use of hollow microcapsules in diagnosis and therapy |
GB9621825D0 (en) * | 1996-10-19 | 1996-12-11 | Andaris Ltd | Microparticles and their use as therapeutic vehicles |
AU5719798A (en) * | 1996-12-31 | 1998-07-31 | Inhale Therapeutic Systems, Inc. | Processes for spray drying aqueous suspensions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes |
EP1498115A1 (en) * | 1997-01-16 | 2005-01-19 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
PT954282E (en) * | 1997-01-16 | 2005-06-30 | Massachusetts Inst Technology | PREPARATION OF PARTICLES FOR INHALATION |
SE9700133D0 (en) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
ATE239447T1 (en) * | 1997-09-29 | 2003-05-15 | Inhale Therapeutic Syst | STABILIZED PREPARATIONS USABLE IN NEBULIZERS |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US6309623B1 (en) * | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
SE9704186D0 (en) | 1997-11-14 | 1997-11-14 | Astra Ab | New composition of matter |
GB9727102D0 (en) * | 1997-12-22 | 1998-02-25 | Andaris Ltd | Microparticles and their therapeutic use |
EP1056484A1 (en) * | 1998-02-20 | 2000-12-06 | Quadrant Healthcare (UK) Limited | Products comprising fibrinogen for use in therapy |
EP1273290A1 (en) * | 1998-06-24 | 2003-01-08 | Advanced Inhalation Research, Inc. | Large porous particles emitted from an inhaler |
ES2198922T3 (en) * | 1998-06-24 | 2004-02-01 | Advanced Inhalation Research, Inc. | LARGE POROUS PARTICLES ISSUED BY AN INHALER. |
AU772798B2 (en) * | 1999-04-21 | 2004-05-06 | 1355540 Ontario Inc. | Formulations for detecting asthma |
US6858199B1 (en) | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
MXPA02006079A (en) | 1999-12-20 | 2004-08-23 | Nicholas J Kerkhof | Process for producing nanometer particles by fluid bed spraydrying. |
US8771740B2 (en) * | 1999-12-20 | 2014-07-08 | Nicholas J. Kerkhof | Process for producing nanoparticles by spray drying |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
AU2001264789A1 (en) * | 2000-06-08 | 2001-12-17 | Eli Lilly And Company | Protein powder for pulmonary delivery |
ATE355849T1 (en) * | 2000-12-21 | 2007-03-15 | Nektar Therapeutics | STORAGE-Stable POWDER COMPOSITIONS WITH INTERLEUKIN-4 RECEPTOR |
GB0111420D0 (en) * | 2001-05-10 | 2001-07-04 | Biovector Solutions Ltd | Soluble polymer systems for drug delivery |
WO2003037303A1 (en) | 2001-11-01 | 2003-05-08 | Nektar Therapeutics | Spray drying methods and compositions thereof |
ATE508735T1 (en) | 2001-12-19 | 2011-05-15 | Novartis Ag | PULMONARY ADMINISTRATION OF AMINOGLYCOSIDES |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
EP1589901A4 (en) | 2002-12-20 | 2006-08-09 | Generipharm Inc | Intracutaneous injection |
AU2004251623B2 (en) | 2003-05-28 | 2010-03-18 | Novartis Ag | Spray drying of an alcoholic aqueous solution for the manufacture of a water-in-soluble active agentmicroparticle with a partial or complete amino acid and/or phospholipid coat |
EP1646445A4 (en) | 2003-07-18 | 2007-09-19 | Baxter Int | Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation |
DE10339197A1 (en) * | 2003-08-22 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried amorphous powder with low residual moisture and good storage stability |
US7723306B2 (en) | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
US8333995B2 (en) | 2004-05-12 | 2012-12-18 | Baxter International, Inc. | Protein microspheres having injectable properties at high concentrations |
JP2010505883A (en) | 2006-10-12 | 2010-02-25 | ザ ユニバーシティー オブ クイーンズランド | Compositions and methods for modulating immune responses |
EP2050437A1 (en) * | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
UA90013C2 (en) * | 2008-03-19 | 2010-03-25 | Давид Анатолійович Нога | Pharmaceutical composition containing insulin and process for the preparation thereof |
US11524058B2 (en) | 2008-09-29 | 2022-12-13 | The Corporation Of Mercer University | Oral dissolving films containing microencapsulated vaccines and methods of making same |
US10463608B2 (en) | 2008-09-29 | 2019-11-05 | The Corporation Of Mercer University | Microneedle-based transdermal delivery system and method of making same |
CA2738855A1 (en) | 2008-09-29 | 2010-04-01 | The Corporation Of Mercer University | Nanospheres encapsulating bioactive material and method for formulation of nanospheres |
US10004790B2 (en) | 2008-09-29 | 2018-06-26 | The Corporation Of Mercer University | Nanospheres encapsulating bioactive material and method for formulation of nanospheres |
US9827205B2 (en) | 2008-12-12 | 2017-11-28 | Mallinckrodt Pharma Ip Trading D.A.C. | Dry powder fibrin sealant |
EP2216054A1 (en) | 2009-02-06 | 2010-08-11 | ProFibrix BV | Biodegradable extravascular support |
ES2593584T3 (en) * | 2009-05-28 | 2016-12-09 | Profibrix Bv | Dry powder fibrin sealant |
GB0909136D0 (en) | 2009-05-28 | 2009-07-01 | Profibrix Bv | Dry powder composition |
GB0909131D0 (en) | 2009-05-28 | 2009-07-01 | Quadrant Drug Delivery Ltd | Dry powder fibrin sealant |
WO2011005756A1 (en) | 2009-07-06 | 2011-01-13 | Puretech Ventures, Llc | Delivery of agents targeted to microbiota niches |
KR20120125465A (en) | 2010-01-08 | 2012-11-15 | 프로피브릭스 비.브이. | Dry powder fibrin sealant |
WO2012012460A1 (en) | 2010-07-19 | 2012-01-26 | Xeris Pharmaceuticals, Inc. | Stable glucagon formulations for the treatment of hypoglycemia |
AU2011325857A1 (en) | 2010-11-01 | 2013-05-02 | University Of Technology, Sydney | Immune-modulating agents and uses therefor |
EP3225235B1 (en) | 2011-03-10 | 2020-12-16 | Xeris Pharmaceuticals, Inc. | Stable peptide formulations for parenteral injection |
CN105853348B (en) | 2011-03-10 | 2019-08-30 | Xeris药物公司 | Parenteral injection stablizing solution |
RU2013155713A (en) | 2011-07-06 | 2015-08-20 | Профибрикс Бв | COMPOSITIONS FOR TREATMENT OF THE RAS |
KR102007057B1 (en) | 2011-10-31 | 2019-08-02 | 엑스에리스 파머수티클스, 인크. | Formulations for the treatment of diabetes |
EP2836204B1 (en) | 2012-04-13 | 2020-07-08 | GlaxoSmithKline Intellectual Property Development Limited | Aggregate particles |
US10350314B2 (en) * | 2012-06-26 | 2019-07-16 | Ge Healthcare As | Preparation of composition comprising gas microbubbles |
US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
US9597339B2 (en) | 2013-02-01 | 2017-03-21 | Glialogix, Inc. | Compositions and methods for the treatment of neurodegenerative and other diseases |
WO2014124096A1 (en) | 2013-02-06 | 2014-08-14 | Perosphere Inc. | Stable glucagon formulations |
US9018162B2 (en) | 2013-02-06 | 2015-04-28 | Xeris Pharmaceuticals, Inc. | Methods for rapidly treating severe hypoglycemia |
WO2015054280A1 (en) | 2013-10-08 | 2015-04-16 | Lam Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
EP4218742A1 (en) | 2014-04-04 | 2023-08-02 | AI Therapeutics, Inc. | An inhalable rapamycin formulation for treating age-related conditions |
WO2015179918A1 (en) | 2014-05-27 | 2015-12-03 | The University Of Queensland | Modulation of cellular stress |
EP3185932A1 (en) | 2014-08-06 | 2017-07-05 | Xeris Pharmaceuticals, Inc. | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
KR20170095807A (en) | 2014-10-07 | 2017-08-23 | 램 테라퓨틱스, 인코포레이티드 | An inhalable rapamycin formulation for the treatment of pulmonary hypertension |
WO2016196976A1 (en) | 2015-06-04 | 2016-12-08 | Xeris Pharmaceuticals, Inc. | Glucagon delivery apparatuses and related methods |
US9649364B2 (en) | 2015-09-25 | 2017-05-16 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic formulations in aprotic polar solvents |
EP3307295A1 (en) | 2015-06-10 | 2018-04-18 | Xeris Pharmaceuticals, Inc. | Use of low dose glucagon |
US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
WO2017062463A1 (en) | 2015-10-05 | 2017-04-13 | The Corporation Of Mercer University | Nanospheres encapsulating bioactive material and method for formulation of nanospheres |
US11628208B2 (en) | 2015-10-05 | 2023-04-18 | The Corporation Of Mercer University | System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins |
TW201818933A (en) | 2016-10-21 | 2018-06-01 | 美商吉利亞洛吉克斯公司 | Compositions and methods for the treatment of neurodegenerative and other diseases |
JP7299166B2 (en) | 2017-06-02 | 2023-06-27 | ゼリス ファーマシューティカルズ インコーポレイテッド | Precipitation-resistant small molecule drug formulation |
WO2021090214A2 (en) * | 2019-11-04 | 2021-05-14 | Alesco S.R.L. | Sucrosomial® berberine, its compositions and their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2115065C (en) * | 1992-06-12 | 2000-10-03 | Kiyoyuki Sakon | Ultrafine particle powder for inhalation and method for production thereof |
CA2115444C (en) * | 1992-06-12 | 2000-10-03 | Yuji Makino | Preparation for intratracheobronchial administration |
-
1995
- 1995-09-26 MX MX9702357A patent/MX9702357A/en unknown
- 1995-09-26 RU RU97106769A patent/RU2147226C1/en not_active IP Right Cessation
- 1995-09-26 KR KR1019970702043A patent/KR970705979A/en not_active Application Discontinuation
- 1995-09-26 CA CA002199954A patent/CA2199954A1/en not_active Abandoned
- 1995-09-26 CZ CZ97924A patent/CZ92497A3/en unknown
- 1995-09-26 EP EP95932122A patent/EP0783298A1/en not_active Ceased
- 1995-09-26 PL PL95319600A patent/PL319600A1/en unknown
- 1995-09-26 NZ NZ292980A patent/NZ292980A/en not_active IP Right Cessation
- 1995-09-26 BR BR9509171A patent/BR9509171A/en not_active Application Discontinuation
- 1995-09-26 AU AU35302/95A patent/AU701440B2/en not_active Ceased
- 1995-09-26 HU HU9702161A patent/HUT77373A/en unknown
- 1995-09-26 JP JP8511495A patent/JPH10506406A/en not_active Ceased
- 1995-09-26 WO PCT/GB1995/002279 patent/WO1996009814A1/en not_active Application Discontinuation
- 1995-09-29 ZA ZA958239A patent/ZA958239B/en unknown
-
1997
- 1997-03-26 NO NO971438A patent/NO971438D0/en not_active Application Discontinuation
- 1997-04-01 FI FI971332A patent/FI971332A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUT77373A (en) | 1998-03-30 |
KR970705979A (en) | 1997-11-03 |
AU701440B2 (en) | 1999-01-28 |
CZ92497A3 (en) | 1997-08-13 |
BR9509171A (en) | 1997-09-16 |
EP0783298A1 (en) | 1997-07-16 |
ZA958239B (en) | 1996-09-30 |
PL319600A1 (en) | 1997-08-18 |
CA2199954A1 (en) | 1996-04-04 |
NZ292980A (en) | 1999-02-25 |
WO1996009814A1 (en) | 1996-04-04 |
AU3530295A (en) | 1996-04-19 |
JPH10506406A (en) | 1998-06-23 |
RU2147226C1 (en) | 2000-04-10 |
FI971332A0 (en) | 1997-04-01 |
NO971438L (en) | 1997-03-26 |
FI971332A (en) | 1997-04-01 |
NO971438D0 (en) | 1997-03-26 |
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